|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 666 for Tcf3

<< First    < Previous  |  Next >    Last >>
0.045s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6929 | TCF3
Type: gene
Organism: human
•
•
•
•
•
Gene
100101779 | tcf3
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
171046 | Tcf3
Type: gene
Organism: rat
•
•
•
•
•
Gene
485079 | TCF3
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
468650 | TCF3
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
530616 | TCF3
Type: gene
Organism: cattle
•
•
•
•
•
Gene
395146 | TCF3
Type: gene
Organism: chicken
•
•
•
•
•
Gene
721325 | TCF3
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:98510 | Tcf3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Gene
29844 | TFPT
Type: gene
Organism: human
•
•
•
•
•
Publication
24909826 | J:276270
 
First Author: Miao Q
Year: 2014
Journal: Nat Commun
Title: Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2.
Volume: 5
Pages: 4088
•
•
•
•
•
Publication
19718027 | J:155012
First Author: Nguyen H
Year: 2009
Journal: Nat Genet
Title: Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.
Volume: 41
Issue: 10
Pages: 1068-75
•
•
•
•
•
Publication
25038042 | J:213957
First Author: Howard JM
Year: 2014
Journal: Development
Title: Tcf3 expression marks both stem and progenitor cells in multiple epithelia.
Volume: 141
Issue: 16
Pages: 3143-52
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7339285
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7387101
Age: embryonic day 14.5
Image: 6A Tcf3 - E14.5
Note: Expression is seen in basal progenitor cells.
Specimen Label: 6A Tcf3 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7339285
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7387101
Age: embryonic day 16.5
Image: 6A Tcf3 - E16.5
Note: Expression is seen in basal progenitor cells.
Specimen Label: 6A Tcf3 - E16.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7339285
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7387101
Age: embryonic day 18.5
Image: 6A Tcf3 - E18.5
Note: Expression is seen in basal progenitor cells.
Specimen Label: 6A Tcf3 - E18.5
Detected: true
Specimen Num: 5
•
•
•
•
•
Publication
21685894 | J:174449
First Author: Yi F
Year: 2011
Journal: Nat Cell Biol
Title: Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal.
Volume: 13
Issue: 7
Pages: 762-70
•
•
•
•
•
Protein
A1A550
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
•
•
•
•
•
Protein
A1A549
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: false
•
•
•
•
•
Publication
23658527 | J:197133
First Author: Atlasi Y
Year: 2013
Journal: PLoS Genet
Title: Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.
Volume: 9
Issue: 5
Pages: e1003424
•
•
•
•
•
Publication
24832538 | J:216337
First Author: Kuwahara A
Year: 2014
Journal: PLoS One
Title: Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development.
Volume: 9
Issue: 5
Pages: e94408
•
•
•
•
•
Publication
22270545 | J:320729
First Author: Solberg N
Year: 2012
Journal: Mol Cell Biochem
Title: Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites.
Volume: 365
Issue: 1-2
Pages: 53-63
•
•
•
•
•
Publication
37684687 | J:340405
First Author: Talley MJ
Year: 2023
Journal: Neural Dev
Title: Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon.
Volume: 18
Issue: 1
Pages: 5
•
•
•
•
•
Protein
Q3TPB1
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
•
•
•
•
•
Protein
Q3U1J1
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RQ56
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RPD5
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
•
•
•
•
•
Protein
F8WIZ9
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
•
•
•
•
•
Publication
21685889 | J:174453
First Author: Wray J
Year: 2011
Journal: Nat Cell Biol
Title: Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
Volume: 13
Issue: 7
Pages: 838-45
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7576988
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7577013
Age: embryonic day 13.5
Image: 6F
Note: The expression pattern of Tcf4 and Tcf3 were mutually exclusive.
Specimen Label: 6F
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
11700047 | J:72901
First Author: Brambillasca F
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Promoter analysis of TFPT (FB1), a molecular partner of TCF3 (E2A) in childhood acute lymphoblastic leukemia.
Volume: 288
Issue: 5
Pages: 1250-7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7576988
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7577013
Age: embryonic day 13.5
Image: 6E
Note: The expression pattern of Tcf4 and Tcf3 were mutually exclusive. An expansion in the expression domain was seen, compared with the control.
Specimen Label: 6E
Detected: true
Specimen Num: 1
•
•
•
•
•
Gene
85423 | Tfpt
Type: gene
Organism: rat
•
•
•
•
•
Gene
611475 | TFPT
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
506610 | TFPT
Type: gene
Organism: cattle
•
•
•
•
•
Gene
796934 | tfpt
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
720296 | TFPT
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
107969803 | TFPT
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
108697743 | LOC108697743
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Publication
17018284 | J:116057
First Author: Nguyen H
Year: 2006
Journal: Cell
Title: Tcf3 governs stem cell features and represses cell fate determination in skin.
Volume: 127
Issue: 1
Pages: 171-83
•
•
•
•
•
Publication
10330184 | J:55022
First Author: Smith KS
Year: 1999
Journal: Mol Cell Biol
Title: Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice.
Volume: 19
Issue: 6
Pages: 4443-51
•
•
•
•
•
Publication
19181846 | J:144955
First Author: Semerad CL
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors.
Volume: 106
Issue: 6
Pages: 1930-5
•
•
•
•
•
Publication
15104122 | J:88032
First Author: Zhuang Y
Year: 2004
Journal: Mol Immunol
Title: Regulation of E2A gene expression in B-lymphocyte development.
Volume: 40
Issue: 16
Pages: 1165-77
•
•
•
•
•
Publication
20062079 | J:160392
First Author: Yamasaki N
Year: 2010
Journal: Oncogene
Title: Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.
Volume: 29
Issue: 13
Pages: 1963-75
•
•
•
•
•
Publication
21730189 | J:174356
First Author: Lluis F
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications.
Volume: 108
Issue: 29
Pages: 11912-7
•
•
•
•
•
Publication
28211472 | J:244024
 
First Author: Fukuda R
Year: 2017
Journal: Nat Commun
Title: Proteolysis regulates cardiomyocyte maturation and tissue integration.
Volume: 8
Pages: 14495
•
•
•
•
•
Publication
35401501 | J:323196
 
First Author: Veiga DFT
Year: 2022
Journal: Front Immunol
Title: Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia.
Volume: 13
Pages: 867443
•
•
•
•
•
Publication
11937548 | J:75746
First Author: Pan L
Year: 2002
Journal: J Immunol
Title: An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.
Volume: 168
Issue: 8
Pages: 3923-32
•
•
•
•
•
Publication
21857655 | J:176462
First Author: Miyazaki M
Year: 2011
Journal: Nat Immunol
Title: The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.
Volume: 12
Issue: 10
Pages: 992-1001
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: TCF3 fusion partner homolog
Type: chain
End: 259
•
•
•
•
•
Publication
36330928 | J:331303
 
First Author: Kantzer CG
Year: 2022
Journal: Development
Title: ID1 and CEBPA coordinate epidermal progenitor cell differentiation.
Volume: 149
Issue: 22
•
•
•
•
•
Protein Coding Gene
MGI:1916964 | Tfpt
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
30705426 | J:299678
First Author: Li H
Year: 2019
Journal: Mol Psychiatry
Title: Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.
Volume: 24
Issue: 8
Pages: 1235-1246
•
•
•
•
•
Publication
20725507 | J:311994
   
First Author: Livnat I
Year: 2010
Journal: Front Cell Neurosci
Title: PAF-AH Catalytic Subunits Modulate the Wnt Pathway in Developing GABAergic Neurons.
Volume: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7641686
Assay Type: RNA in situ
Annotation Date: 2024-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7641888
Age: embryonic day 12.0
Note: Expression was detected in the rostral tip of the telencephalon (the location of the developing olfactory bulb), prior to the arrival of cells from the rostral migratory stream.
Specimen Label: S1 Tcf3
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7641686
Assay Type: RNA in situ
Annotation Date: 2024-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:7641888
Age: embryonic day 11.0
Note: Expression was detected in the rostral tip of the telencephalon (the location of the developing olfactory bulb), prior to the arrival of cells from the rostral migratory stream.
Specimen Label: S2 Tcf3
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
28514688 | J:258946
First Author: Miyazaki M
Year: 2017
Journal: Immunity
Title: The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.
Volume: 46
Issue: 5
Pages: 818-834.e4
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0015585 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0017503 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0017481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0017442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0017443 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0017266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_98510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0017897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0016833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0017238 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0017344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0017338 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0017415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0017364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0017938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0016614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0016893 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0030998 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0016403 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
8112613 | J:17006
First Author: Kajimoto Y
Year: 1994
Journal: Gene
Title: Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1.
Volume: 139
Issue: 2
Pages: 247-9
•
•
•
•
•
Publication
7875598 | J:23303
First Author: Watada H
Year: 1995
Journal: Gene
Title: Ubiquitous, but variable, expression of two alternatively spliced mRNAs encoding mouse homologues of transcription factors E47 and E12.
Volume: 153
Issue: 2
Pages: 255-9
•
•
•
•
•
Publication
14697510 | J:87915
 
First Author: Hata K
Year: 2004
Journal: Gene
Title: Genomic organization and characterization of the promoter for the E2A gene.
Volume: 325
Pages: 53-61
•
•
•
•
•
Publication
18195039 | J:132669
First Author: Nie L
Year: 2008
Journal: Mol Cell Biol
Title: Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals.
Volume: 28
Issue: 6
Pages: 2078-90
•
•
•
•
•
Publication
22354994 | J:183781
First Author: Teachenor R
Year: 2012
Journal: Mol Cell Biol
Title: Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.
Volume: 32
Issue: 9
Pages: 1671-82
•
•
•
•
•
Publication
19752184 | J:153423
First Author: Beck K
Year: 2009
Journal: J Exp Med
Title: Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.
Volume: 206
Issue: 10
Pages: 2271-84
•
•
•
•
•
Publication
15027899 | J:88415
First Author: Pan L
Year: 2004
Journal: Immunology
Title: Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes.
Volume: 111
Issue: 2
Pages: 147-54
•
•
•
•
•
Publication
38155245 | J:345789
First Author: Parriott G
Year: 2024
Journal: Leukemia
Title: Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL.
Volume: 38
Issue: 3
Pages: 491-501
•
•
•
•
•
Publication
30659202 | J:270745
First Author: Hemmer MC
Year: 2019
Journal: Nat Commun
Title: E47 modulates hepatic glucocorticoid action.
Volume: 10
Issue: 1
Pages: 306
•
•
•
•
•
Publication
24470503 | J:209822
First Author: Hauser J
Year: 2014
Journal: J Immunol
Title: Allelic exclusion of IgH through inhibition of E2A in a VDJ recombination complex.
Volume: 192
Issue: 5
Pages: 2460-70
•
•
•
•
•
Publication
9584174 | J:47671
First Author: Zhuang Y
Year: 1998
Journal: Mol Cell Biol
Title: Functional replacement of the mouse E2A gene with a human HEB cDNA.
Volume: 18
Issue: 6
Pages: 3340-9
•
•
•
•
•
Publication
22581853 | J:188878
First Author: Verma-Gaur J
Year: 2012
Journal: J Immunol
Title: Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A.
Volume: 188
Issue: 12
Pages: 6175-83
•
•
•
•
•
Publication
1465450 | J:79163
First Author: Zhuang Y
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis.
Volume: 89
Issue: 24
Pages: 12132-6
•
•
•
•
•
Publication
11224524 | J:118964
First Author: Kee BL
Year: 2001
Journal: Nat Immunol
Title: Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta.
Volume: 2
Issue: 3
Pages: 242-7
•
•
•
•
•
Publication
9892611 | J:52939
First Author: Bain G
Year: 1999
Journal: J Exp Med
Title: Positive and negative regulation of V(D)J recombination by the E2A proteins.
Volume: 189
Issue: 2
Pages: 289-300
•
•
•
•
•
Publication
9234734 | J:41658
First Author: Bain G
Year: 1997
Journal: Mol Cell Biol
Title: E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas.
Volume: 17
Issue: 8
Pages: 4782-91
•
•
•
•
•
Publication
9047236 | J:38711
First Author: Bain G
Year: 1997
Journal: Immunity
Title: Both E12 and E47 allow commitment to the B cell lineage.
Volume: 6
Issue: 2
Pages: 145-54
•
•
•
•
•
Publication
18093539 | J:129170
First Author: Agata Y
Year: 2007
Journal: Immunity
Title: Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47.
Volume: 27
Issue: 6
Pages: 871-84
•
•
•
•
•
Publication
18674933 | J:140043
First Author: Dias S
Year: 2008
Journal: Immunity
Title: E2A proteins promote development of lymphoid-primed multipotent progenitors.
Volume: 29
Issue: 2
Pages: 217-27
•
•
•
•
•
Publication
18941177 | J:140750
First Author: Yang Q
Year: 2008
Journal: J Immunol
Title: E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Volume: 181
Issue: 9
Pages: 5885-94
•
•
•
•
•
Publication
21273306 | J:170504
First Author: Yang Q
Year: 2011
Journal: Blood
Title: E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction.
Volume: 117
Issue: 13
Pages: 3529-38
•
•
•
•
•
Publication
19822014 | J:154788
 
First Author: Jones ME
Year: 2009
Journal: BMC Dev Biol
Title: A tamoxifen inducible knock-in allele for investigation of E2A function.
Volume: 9
Pages: 51
•
•
•
•
•
Publication
23752615 | J:204823
First Author: Zhang P
Year: 2013
Journal: J Immunol
Title: Notch-regulated periphery B cell differentiation involves suppression of E protein function.
Volume: 191
Issue: 2
Pages: 726-36
•
•
•
•
•
Publication
21828274 | J:211239
First Author: Yoon SJ
Year: 2011
Journal: Genes Dev
Title: HEB and E2A function as SMAD/FOXH1 cofactors.
Volume: 25
Issue: 15
Pages: 1654-61
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom