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Search results 1 to 100 out of 796 for Tcf7

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0.022s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Transcription factor 7 (Tcf7), also referred to by the symbol Tcf1, is a transcriptional activator involved in T-cell lymphocyte differentiation []. It is necessary for the survival of CD4+ CD8+ immature thymocytes []. Tcf7 has multiple isoforms, and there is functional differences between these isoforms [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 334  
Fragment?: false
Publication
First Author: Van de Wetering M
Year: 1996
Journal: Mol Cell Biol
Title: Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties.
Volume: 16
Issue: 3
Pages: 745-52
Publication
First Author: Ioannidis V
Year: 2001
Journal: Nat Immunol
Title: The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.
Volume: 2
Issue: 8
Pages: 691-7
Publication
First Author: Okamura RM
Year: 1998
Journal: Immunity
Title: Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1.
Volume: 8
Issue: 1
Pages: 11-20
Publication
First Author: Huls G
Year: 2013
Journal: Leukemia
Title: Loss of Tcf7 diminishes hematopoietic stem/progenitor cell function.
Volume: 27
Issue: 7
Pages: 1613-4
Publication
First Author: Mayer K
Year: 1995
Journal: Biochim Biophys Acta
Title: The human high mobility group (HMG)-box transcription factor TCF-1: novel isoforms due to alternative splicing and usage of a new exon IXA.
Volume: 1263
Issue: 2
Pages: 169-72
Protein
Organism: Mus musculus
Length: 192  
Fragment?: true
Protein
Organism: Mus musculus
Length: 419  
Fragment?: false
Protein
Organism: Mus musculus
Length: 303  
Fragment?: false
Protein
Organism: Mus musculus
Length: 419  
Fragment?: false
Publication      
First Author: Li Q
Year: 2018
Journal: Mol Cell Biol
Title: TCF7/TCF1 feedback controls osteocalcin signaling in brown adipocytes independent of canonical WNT/β-catenin pathway.
Publication
First Author: Ladle BH
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation.
Volume: 113
Issue: 38
Pages: 10631-6
Publication
First Author: Barra MM
Year: 2015
Journal: PLoS One
Title: Premature expression of Foxp3 in double-negative thymocytes.
Volume: 10
Issue: 5
Pages: e0127038
Publication
First Author: Gautam S
Year: 2019
Journal: Nat Immunol
Title: The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.
Volume: 20
Issue: 3
Pages: 337-349
Publication
First Author: Choi YS
Year: 2015
Journal: Nat Immunol
Title: LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.
Volume: 16
Issue: 9
Pages: 980-90
Publication
First Author: Yu S
Year: 2012
Journal: Immunity
Title: The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.
Volume: 37
Issue: 5
Pages: 813-26
Publication
First Author: Yang Q
Year: 2013
Journal: Immunity
Title: T cell factor 1 is required for group 2 innate lymphoid cell generation.
Volume: 38
Issue: 4
Pages: 694-704
Publication
First Author: Kim MV
Year: 2013
Journal: Immunity
Title: The transcription factor Foxo1 controls central-memory CD8+ T cell responses to infection.
Volume: 39
Issue: 2
Pages: 286-97
Publication
First Author: Shan Q
Year: 2017
Journal: Nat Immunol
Title: The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.
Volume: 18
Issue: 8
Pages: 931-939
Publication
First Author: Kaur K
Year: 2015
Journal: Diabetes
Title: Elevated Hepatic miR-22-3p Expression Impairs Gluconeogenesis by Silencing the Wnt-Responsive Transcription Factor Tcf7.
Volume: 64
Issue: 11
Pages: 3659-69
Publication
First Author: Herzig Y
Year: 2017
Journal: Nat Immunol
Title: Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Volume: 18
Issue: 2
Pages: 161-172
Publication
First Author: Xu L
Year: 2017
Journal: Immunity
Title: The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells.
Volume: 47
Issue: 3
Pages: 538-551.e5
Publication
First Author: Donnarumma T
Year: 2016
Journal: Cell Rep
Title: Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.
Volume: 17
Issue: 6
Pages: 1571-1583
Publication
First Author: Campbell JE
Year: 2016
Journal: Nat Med
Title: TCF1 links GIPR signaling to the control of beta cell function and survival.
Volume: 22
Issue: 1
Pages: 84-90
Publication
First Author: Railo A
Year: 2009
Journal: Exp Cell Res
Title: Genomic response to Wnt signalling is highly context-dependent--evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets.
Volume: 315
Issue: 16
Pages: 2690-704
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Oosterwegel M
Year: 1991
Journal: J Exp Med
Title: Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.
Volume: 173
Issue: 5
Pages: 1133-42
Publication  
First Author: Wang Y
Year: 2019
Journal: Front Immunol
Title: The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection.
Volume: 10
Pages: 169
Publication
First Author: Im SJ
Year: 2016
Journal: Nature
Title: Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Volume: 537
Issue: 7620
Pages: 417-421
Publication
First Author: Xu Z
Year: 2017
Journal: J Immunol
Title: Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.
Volume: 198
Issue: 9
Pages: 3404-3409
Publication
First Author: Gullicksrud JA
Year: 2017
Journal: J Immunol
Title: Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection.
Volume: 199
Issue: 3
Pages: 911-919
Publication
First Author: Verbeek S
Year: 1995
Journal: Nature
Title: An HMG-box-containing T-cell factor required for thymocyte differentiation.
Volume: 374
Issue: 6517
Pages: 70-4
Publication
First Author: Jeannet G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory.
Volume: 107
Issue: 21
Pages: 9777-82
Publication
First Author: van Loosdregt J
Year: 2013
Journal: Immunity
Title: Canonical Wnt signaling negatively modulates regulatory T cell function.
Volume: 39
Issue: 2
Pages: 298-310
Publication
First Author: Zhou X
Year: 2010
Journal: Immunity
Title: Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1.
Volume: 33
Issue: 2
Pages: 229-40
Publication
First Author: Siddiqui I
Year: 2019
Journal: Immunity
Title: Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Volume: 50
Issue: 1
Pages: 195-211.e10
Publication
First Author: Utzschneider DT
Year: 2016
Journal: Immunity
Title: T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections.
Volume: 45
Issue: 2
Pages: 415-27
Publication
First Author: Yu Q
Year: 2011
Journal: J Immunol
Title: T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis.
Volume: 186
Issue: 7
Pages: 3946-52
Publication
First Author: Yu S
Year: 2013
Journal: Blood
Title: TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes.
Volume: 121
Issue: 19
Pages: 4008-9
Publication
First Author: Held W
Year: 1999
Journal: Immunity
Title: Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1.
Volume: 11
Issue: 4
Pages: 433-42
Publication
First Author: Johnson JL
Year: 2018
Journal: Immunity
Title: Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells.
Volume: 48
Issue: 2
Pages: 243-257.e10
Publication
First Author: Ma J
Year: 2011
Journal: PLoS One
Title: Critical role of TCF-1 in repression of the IL-17 gene.
Volume: 6
Issue: 9
Pages: e24768
Publication
First Author: Schilham MW
Year: 1998
Journal: J Immunol
Title: Critical involvement of Tcf-1 in expansion of thymocytes.
Volume: 161
Issue: 8
Pages: 3984-91
Publication
First Author: Ioannidis V
Year: 2003
Journal: J Immunol
Title: Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1.
Volume: 171
Issue: 2
Pages: 769-75
Publication
First Author: Ohteki T
Year: 1996
Journal: Eur J Immunol
Title: Selectively impaired development of intestinal T cell receptor gamma delta+ cells and liver CD4+ NK1+ T cell receptor alpha beta+ cells in T cell factor-1-deficient mice.
Volume: 26
Issue: 2
Pages: 351-5
Publication
First Author: Tiemessen MM
Year: 2012
Journal: PLoS Biol
Title: The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas.
Volume: 10
Issue: 11
Pages: e1001430
Publication
First Author: van de Wetering M
Year: 1992
Journal: J Biol Chem
Title: The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.
Volume: 267
Issue: 12
Pages: 8530-6
Publication
First Author: Park MW
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of the DNA binding by the TCF-1 binding RNA aptamer.
Volume: 330
Issue: 1
Pages: 11-7
Publication
First Author: Cho S
Year: 2017
Journal: J Immunol
Title: A Novel miR-24-TCF1 Axis in Modulating Effector T Cell Responses.
Volume: 198
Issue: 10
Pages: 3919-3926
Publication
First Author: Chen Z
Year: 2019
Journal: Immunity
Title: TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Volume: 51
Issue: 5
Pages: 840-855.e5
GXD Expression        
Probe: MGI:3053715
Assay Type: RT-PCR
Annotation Date: 2004-10-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3053724
Age: postnatal adult
Specimen Num: 7
GXD Expression      
Probe: MGI:3693537
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693793
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:3693537
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693793
Age: embryonic day 14.5
Specimen Num: 2
GXD Expression      
Probe: MGI:3813331
Assay Type: RT-PCR
Annotation Date: 2008-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738219
Stage: TS19
Assay Id: MGI:3813340
Age: embryonic day 11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3813331
Assay Type: RT-PCR
Annotation Date: 2008-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738220
Stage: TS20
Assay Id: MGI:3813340
Age: embryonic day 12.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3813331
Assay Type: RT-PCR
Annotation Date: 2008-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738222
Stage: TS22
Assay Id: MGI:3813340
Age: embryonic day 14.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816948
Age: embryonic day 4.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816948
Age: embryonic day 1.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5296248
Assay Type: Northern blot
Annotation Date: 2011-11-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5296249
Age: postnatal day 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816948
Age: embryonic day 2.0
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3708323
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:3708354
Age: embryonic day 13.5
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3708323
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:3708354
Age: embryonic day 16.5
Image: 5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816948
Age: embryonic day 2.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816948
Age: embryonic day 3.0
Detected: true
Specimen Num: 5
GXD Expression        
Probe: MGI:3053715
Assay Type: RT-PCR
Annotation Date: 2004-10-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3053724
Age: postnatal adult
Specimen Num: 6
GXD Expression    
Probe: MGI:6161233
Assay Type: Western blot
Annotation Date: 2018-06-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1685327
Stage: TS27
Assay Id: MGI:6161245
Age: postnatal day 1
Image: 7
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816948
Age: embryonic day 3.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816948
Age: embryonic day 4.5
Detected: true
Specimen Num: 7
GXD Expression        
Probe: MGI:3053715
Assay Type: RT-PCR
Annotation Date: 2004-10-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876826
Stage: TS26
Assay Id: MGI:3053724
Age: embryonic day 18.5
Specimen Num: 5
GXD Expression    
Probe: MGI:6161233
Assay Type: Western blot
Annotation Date: 2018-06-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:6161245
Age: postnatal day 1
Image: 7
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3816144
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816948
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845710
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4849174
Age: embryonic day 9.5
Note: Staining is present in the mandibular arch.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845710
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4849174
Age: embryonic day 10.5
Note: Staining is present in the mandibular arch.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:17403
Assay Type: RNA in situ
Annotation Date: 2011-11-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5296031
Age: embryonic day 9.5
Image: 4A
Note: It is likely expression occurs in neural crest-derived cells.
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:17403
Assay Type: RNA in situ
Annotation Date: 2011-11-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5296031
Age: embryonic day 10.5
Image: 5C
Note: It is likely expression occurs in neural crest-derived cells.
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3724584
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421244
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5001372
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2918123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541927
Age: embryonic day 15.5
Image: GUDMAP:13657
Detected: true
Specimen Num: 1