|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 58 out of 58 for Tchhl1

0.021s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Trichohyalin-like protein 1 (TCHHL1) is a member of the fused-type S100 protein family. It contains an N-terminal E-hand domain, one trans-membrane domain and a nuclear localization signal. Its function is not clear. It is expressed in the basal layer of the normal epidermis and may be associated with the proliferation of keratinocytes [].The fused-type S100 protein family is a group of calcium binding S100-related proteins. The 'fused' gene family includes multifunctional epidermal differentiation proteins - profilaggrin, trichohyalin, repetin [], hornerin, and cornulin; functionally these proteins are associated with keratin intermediate filaments and partially crosslinked to the cell envelope. These 'fused' gene proteins contain N-terminal sequence with two Ca-binding EF-hands motif, which may be associated with calcium signalling in epidermal cells and autoprocessing in a calcium-dependent manner. In contrast to S100 proteins, 'fused' gene family proteins contain an extraordinary high number of almost perfect peptide repeats with regular array of polar and charged residues similar to many known cell envelope proteins [].
Protein
Organism: Mus musculus
Length: 638  
Fragment?: false
Publication
First Author: Huber M
Year: 2005
Journal: J Invest Dermatol
Title: Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
Volume: 124
Issue: 5
Pages: 998-1007
Publication
First Author: Wheeler LC
Year: 2016
Journal: PLoS One
Title: Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.
Volume: 11
Issue: 10
Pages: e0164740
Publication
First Author: Yamakoshi T
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Trichohyalin-like 1 protein, a member of fused S100 proteins, is expressed in normal and pathologic human skin.
Volume: 432
Issue: 1
Pages: 66-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6331246
Assay Type: RT-PCR
Annotation Date: 2019-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6331312
Age: embryonic day 17.5
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6331246
Assay Type: RT-PCR
Annotation Date: 2019-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6331325
Age: embryonic day 17.5
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6331246
Assay Type: RT-PCR
Annotation Date: 2019-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6331325
Age: embryonic day 17.5
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6331246
Assay Type: RT-PCR
Annotation Date: 2019-07-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6331361
Age: embryonic day 17.5
Image: S1
Detected: true
Specimen Num: 1
Publication
First Author: Wurm S
Year: 2015
Journal: Genes Dev
Title: Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2.
Volume: 29
Issue: 2
Pages: 144-56
Publication
First Author: Ravasi T
Year: 2004
Journal: Genomics
Title: Probing the S100 protein family through genomic and functional analysis.
Volume: 84
Issue: 1
Pages: 10-22
Publication
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database