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Search results 1 to 81 out of 81 for Tcim

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Hits by Strain

Type Details Score
Gene
56892 | TCIM
Type: gene
Organism: human
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Gene
100145578 | tcim
Type: gene
Organism: frog, western clawed
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Gene
607623 | TCIM
Type: gene
Organism: dog, domestic
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Gene
464136 | TCIM
Type: gene
Organism: chimpanzee
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Gene
684871 | Tcim
Type: gene
Organism: rat
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Gene
617047 | TCIM
Type: gene
Organism: cattle
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Gene
702517 | TCIM
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR039580 | Tcim
Type: Family
Description: Transcriptional and immune response regulator (Tcim; also known as C8orf4 or TC1) is a regulator implicated in cancer and inflammation []. It is highly expressed in several tumours and implicated in tumorigenesis. It plays a role in the mitogen-activated MAPK2/3 signaling pathway, and positively regulates G1-to-S-phase transition of the cell cycle []. It negatively regulates the self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling [].
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Protein Coding Gene
MGI:1916318 | Tcim
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25985737 | -
 
First Author: Zhu P
Year: 2015
Journal: Nat Commun
Title: C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.
Volume: 6
Pages: 7122
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Protein
Q9D915
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: false
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Publication
19684084 | -
First Author: Kim J
Year: 2009
Journal: J Immunol
Title: TC1(C8orf4) is a novel endothelial inflammatory regulator enhancing NF-kappaB activity.
Volume: 183
Issue: 6
Pages: 3996-4002
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Publication
18959821 | -
First Author: Wang YD
Year: 2008
Journal: BMB Rep
Title: TC1 (C8orf4) is involved in ERK1/2 pathway-regulated G(1)- to S-phase transition.
Volume: 41
Issue: 10
Pages: 733-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0030911 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033374 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033159 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916318 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021381 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032030 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
24937306 | J:217318
First Author: Jung Y
Year: 2014
Journal: PLoS One
Title: TC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesis.
Volume: 9
Issue: 6
Pages: e100311
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Publication
25558895 | J:235928
First Author: Heise I
Year: 2015
Journal: Genes Brain Behav
Title: Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome.
Volume: 14
Issue: 2
Pages: 209-16
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_08
Specimen Label: euxassay_002675_08
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_09
Specimen Label: euxassay_002675_09
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_10
Specimen Label: euxassay_002675_10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_11
Specimen Label: euxassay_002675_11
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_12
Specimen Label: euxassay_002675_12
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_14
Specimen Label: euxassay_002675_14
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_15
Specimen Label: euxassay_002675_15
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_16
Specimen Label: euxassay_002675_16
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_17
Specimen Label: euxassay_002675_17
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1792123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_08
Specimen Label: euxassay_002675_08
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1792123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_19
Specimen Label: euxassay_002675_19
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1792123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_20
Specimen Label: euxassay_002675_20
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3595822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548618
Age: embryonic day 14.5
Specimen Label: ED6a 1810011O10Rik nasal epithelium
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_08
Specimen Label: euxassay_002675_08
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822636
Age: embryonic day 14.5
Image: euxassay_002675_19
Specimen Label: euxassay_002675_19
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:1056839
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754722
Stage: TS22
Assay Id: MGI:7548618
Age: embryonic day 14.5
Specimen Label: ED6a 1810011O10Rik
Detected: false
Specimen Num: 1
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Publication
25391964 | J:217538
First Author: Lui JH
Year: 2014
Journal: Nature
Title: Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.
Volume: 515
Issue: 7526
Pages: 264-8
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Publication
30240734 | J:330740
 
First Author: Narayanan R
Year: 2018
Journal: iScience
Title: Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex.
Volume: 4
Pages: 109-126
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Publication
23375831 | J:237827
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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