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Search results 1 to 95 out of 95 for Tctn1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
79600 | TCTN1
Type: gene
Organism: human
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Gene
100145811 | tctn1
Type: gene
Organism: frog, western clawed
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Gene
736949 | TCTN1
Type: gene
Organism: chimpanzee
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Gene
304486 | Tctn1
Type: gene
Organism: rat
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Gene
510513 | TCTN1
Type: gene
Organism: cattle
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Gene
100686623 | TCTN1
Type: gene
Organism: dog, domestic
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Gene
416870 | TCTN1
Type: gene
Organism: chicken
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Gene
100007222 | tctn1
Type: gene
Organism: zebrafish
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Gene
711207 | TCTN1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3603820 | Tctn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
37704658 | J:357564
First Author: Truong HM
Year: 2023
Journal: Nat Commun
Title: The tectonic complex regulates membrane protein composition in the photoreceptor cilium.
Volume: 14
Issue: 1
Pages: 5671
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Publication
16357211 | J:103820
First Author: Reiter JF
Year: 2006
Journal: Genes Dev
Title: Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.
Volume: 20
Issue: 1
Pages: 22-7
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Publication
21725307 | J:176174
First Author: Garcia-Gonzalo FR
Year: 2011
Journal: Nat Genet
Title: A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Volume: 43
Issue: 8
Pages: 776-84
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Publication
26540106 | J:231702
First Author: Yee LE
Year: 2015
Journal: PLoS Genet
Title: Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.
Volume: 11
Issue: 11
Pages: e1005627
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Protein Coding Gene
MGP_CAROLIEiJ_G0027700 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3603820 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029858 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029845 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024280 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028698 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:4461893
Assay Type: RT-PCR
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4461939
Age: embryonic day 11.5
Image: 1
Specimen Label: +/+ Tect
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4461893
Assay Type: RT-PCR
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4461939
Age: embryonic day 11.5
Image: 1
Specimen Label: -/+ Tect
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4461893
Assay Type: RT-PCR
Annotation Date: 2010-07-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4461939
Age: embryonic day 11.5
Image: 1
Specimen Label: -/- Tect
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F section
Specimen Label: 1F section
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F whole mount
Specimen Label: 1F whole mount
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:4461940
Age: embryonic day 7.5
Image: 1D
Note: Expression was detected in the ventral node.
Specimen Label: 1D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:4461940
Age: embryonic day 8.0
Image: 1E
Note: Expression was detected in the ventral epithelium of the node.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607510
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:4461940
Age: embryonic day 6.5
Image: S3B Shh+/+
Specimen Label: S3B Shh+/+
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607510
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:4461940
Age: embryonic day 6.5
Image: S3B Shh-/-
Note: Expression was detected in the node as in wild type.
Specimen Label: S3B Shh-/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4462052
Assay Type: RNA in situ
Annotation Date: 2010-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4462053
Age: embryonic day 9.5
Image: S3C wild type
Specimen Label: S3C wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4462052
Assay Type: RNA in situ
Annotation Date: 2010-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4462053
Age: embryonic day 9.5
Image: S3C Ptch-/-
Specimen Label: S3C Ptch-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F whole mount
Specimen Label: 1F whole mount
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F section
Specimen Label: 1F section
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F whole mount
Specimen Label: 1F whole mount
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F section
Specimen Label: 1F section
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F whole mount
Specimen Label: 1F whole mount
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F section
Specimen Label: 1F section
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F whole mount
Specimen Label: 1F whole mount
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4461940
Age: embryonic day 9.5
Image: 1F section
Specimen Label: 1F section
Detected: true
Specimen Num: 4
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Publication
29725084 | J:284292
First Author: Wang B
Year: 2018
Journal: Cell Death Dis
Title: Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.
Volume: 9
Issue: 5
Pages: 520
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Publication
22179047 | J:178978
First Author: Chih B
Year: 2011
Journal: Nat Cell Biol
Title: A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Volume: 14
Issue: 1
Pages: 61-72
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Publication
26982032 | J:231293
First Author: Li C
Year: 2016
Journal: PLoS Biol
Title: MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone.
Volume: 14
Issue: 3
Pages: e1002416
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Publication
26305592 | J:239783
First Author: Garcia-Gonzalo FR
Year: 2015
Journal: Dev Cell
Title: Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
Volume: 34
Issue: 4
Pages: 400-409
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Publication
21565611 | J:173396
First Author: Sang L
Year: 2011
Journal: Cell
Title: Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.
Volume: 145
Issue: 4
Pages: 513-28
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Publication
28106071 | J:255082
 
First Author: Kurogi S
Year: 2017
Journal: Sci Rep
Title: Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Volume: 7
Pages: 40692
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Allele
Tctn3<tm2(Tctn1)Blnw> | MGI:6343518
Name: tectonic family member 3; targeted mutation 2, Baolin Wang
Allele Type: Targeted
Attribute String: Epitope tag, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tctn3/Tctn3
Background: involves: 129S6/SvEvTac * C57BL/6 * SW
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110982 | Joubert syndrome 13
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Publication
28800946 | J:249241
First Author: Wang C
Year: 2017
Journal: Dev Biol
Title: Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.
Volume: 430
Issue: 1
Pages: 156-165
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Protein
Q9D8A8
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
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Publication
22883145 | -
First Author: Thomas S
Year: 2012
Journal: Am J Hum Genet
Title: TCTN3 mutations cause Mohr-Majewski syndrome.
Volume: 91
Issue: 2
Pages: 372-8
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Protein Domain
IPR040354 | Tectonic
Type: Family
Description: The tectonic-like complex (also known as the B9 complex) is localized at the transition zone of primary cilia and acts as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. The complex is required for hedgehog signalling transduction []. Components of this complex are included in this entry, including tectonic-1 (TCTN1), tectonic-2 (TCTN2) and tectonic-3 (TCTN3). TCTN1 acts as an activation and inhibitor of Hedgehog-mediated patterning of the neural tube []. Mutations in the TCTN3 gene cause Mohr-Majewski syndrome, characterized by abnormalities in the oral cavity, face, and digits [].
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Protein
Q8R2Q6
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Protein
Q2MV57
Organism: Mus musculus/domesticus
Length: 700  
Fragment?: false
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Protein
Q8BZ64
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
A0A0R4J1W4
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
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Protein
B2RUD3
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
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Protein
D6RDQ2
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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