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Search results 1 to 100 out of 2110 for Tek

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Souma T
Year: 2016
Journal: J Clin Invest
Title: Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
Volume: 126
Issue: 7
Pages: 2575-87
Publication
First Author: Puri MC
Year: 1999
Journal: Development
Title: Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.
Volume: 126
Issue: 20
Pages: 4569-80
Publication
First Author: Hamaguchi I
Year: 1999
Journal: Blood
Title: In vitro hematopoietic and endothelial cell development from cells expressing TEK receptor in murine aorta-gonad-mesonephros region.
Volume: 93
Issue: 5
Pages: 1549-56
Publication
First Author: Leu NA
Year: 2009
Journal: PLoS One
Title: Conditional Tek promoter-driven deletion of arginyltransferase in the germ line causes defects in gametogenesis and early embryonic lethality in mice.
Volume: 4
Issue: 11
Pages: e7734
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191457
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tek
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191457
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tek
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191457
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tek
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191457
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tek
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191457
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tek
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191457
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tek
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6184976
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191457
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tek
Detected: true
Specimen Num: 7
Publication
First Author: Dumont DJ
Year: 1994
Journal: Genes Dev
Title: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.
Volume: 8
Issue: 16
Pages: 1897-909
Publication
First Author: Iwama A
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.
Volume: 195
Issue: 1
Pages: 301-9
Publication
First Author: Kugathasan L
Year: 2009
Journal: J Exp Med
Title: The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice.
Volume: 206
Issue: 10
Pages: 2221-34
Publication
First Author: Liepinsh DJ
Year: 2009
Journal: Eur J Immunol
Title: Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus.
Volume: 39
Issue: 10
Pages: 2906-15
Publication
First Author: Higgins SJ
Year: 2018
Journal: J Clin Invest
Title: Tie2 protects the vasculature against thrombus formation in systemic inflammation.
Volume: 128
Issue: 4
Pages: 1471-1484
Publication  
First Author: Zhao Y
Year: 2020
Journal: Front Cell Dev Biol
Title: Stimulating Factors and Origins of Precursor Cells in Traumatic Heterotopic Ossification Around the Temporomandibular Joint in Mice.
Volume: 8
Pages: 445
GXD Expression  
Probe: MGI:17747
Assay Type: RNA in situ
Annotation Date: 1999-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620115
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1343765
Age: embryonic day 9.5
Note: The distribution of tek in arterial walls was similar to that of CD44 mRNA. Single dispersed cells expressing tek mRNA were not detected.
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:17747
Assay Type: RNA in situ
Annotation Date: 1999-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620117
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1343765
Age: embryonic day 10.5
Note: The distribution of tek in arterial walls was similar to that of CD44 mRNA. Single dispersed cells expressing tek mRNA were not detected.
Specimen Label: Not shown
Detected: true
Specimen Num: 2
Publication
First Author: Jones N
Year: 2001
Journal: EMBO Rep
Title: Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function.
Volume: 2
Issue: 5
Pages: 438-45
Publication
First Author: Lekas M
Year: 2012
Journal: PLoS One
Title: Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2.
Volume: 7
Issue: 9
Pages: e43568
Publication
First Author: Zhu Z
Year: 2020
Journal: J Invest Dermatol
Title: Aryl Hydrocarbon Receptor in Cutaneous Vascular Endothelial Cells Restricts Psoriasis Development by Negatively Regulating Neutrophil Recruitment.
Volume: 140
Issue: 6
Pages: 1233-1243.e9
Publication    
First Author: Thomson BR
Year: 2019
Journal: Elife
Title: Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.
Volume: 8
Publication
First Author: Pei W
Year: 2017
Journal: Nature
Title: Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Volume: 548
Issue: 7668
Pages: 456-460
Publication
First Author: Chen L
Year: 2016
Journal: Cancer Res
Title: Tie2 Expression on Macrophages Is Required for Blood Vessel Reconstruction and Tumor Relapse after Chemotherapy.
Volume: 76
Issue: 23
Pages: 6828-6838
Publication  
First Author: Zhang B
Year: 2020
Journal: Exp Eye Res
Title: Essential contribution of macrophage Tie2 signal mediated autophagy in laser-induced choroidal neovascularization.
Volume: 193
Pages: 107972
Publication
First Author: Michael IP
Year: 2017
Journal: BMC Cancer
Title: Angiopoietin-1 deficiency increases tumor metastasis in mice.
Volume: 17
Issue: 1
Pages: 539
Publication
First Author: Busch K
Year: 2015
Journal: Nature
Title: Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.
Volume: 518
Issue: 7540
Pages: 542-6
Publication
First Author: Voskas D
Year: 2008
Journal: J Leukoc Biol
Title: An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice.
Volume: 84
Issue: 1
Pages: 59-67
Publication
First Author: Voskas D
Year: 2005
Journal: Am J Pathol
Title: A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice.
Volume: 166
Issue: 3
Pages: 843-55
Publication
First Author: Kabala PA
Year: 2020
Journal: Rheumatology (Oxford)
Title: Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients.
Volume: 59
Issue: 2
Pages: 426-438
Publication
First Author: Ghosh CC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.
Volume: 109
Issue: 25
Pages: 10024-9
Publication
First Author: Wang W
Year: 2022
Journal: Adv Sci (Weinh)
Title: Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
Volume: 9
Issue: 18
Pages: e2105208
Publication
First Author: Dumont DJ
Year: 1993
Journal: Oncogene
Title: The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.
Volume: 8
Issue: 5
Pages: 1293-301
Publication
First Author: Jakab M
Year: 2022
Journal: Cancer Res
Title: Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy.
Volume: 82
Issue: 7
Pages: 1353-1364
Publication
First Author: Fan T
Year: 2022
Journal: Commun Biol
Title: Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction.
Volume: 5
Issue: 1
Pages: 81
Publication
First Author: Schlaeger TM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.
Volume: 94
Issue: 7
Pages: 3058-63
Publication
First Author: Schnürch H
Year: 1993
Journal: Development
Title: Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage.
Volume: 119
Issue: 3
Pages: 957-68
Publication
First Author: Takakura N
Year: 1998
Journal: Immunity
Title: Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis.
Volume: 9
Issue: 5
Pages: 677-86
Publication
First Author: Tang Y
Year: 2010
Journal: Genesis
Title: The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells.
Volume: 48
Issue: 9
Pages: 563-7
Publication
First Author: Wolfram JA
Year: 2009
Journal: Am J Pathol
Title: Keratinocyte but not endothelial cell-specific overexpression of Tie2 leads to the development of psoriasis.
Volume: 174
Issue: 4
Pages: 1443-58
Publication
First Author: Braun LJ
Year: 2020
Journal: Blood
Title: Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2.
Volume: 136
Issue: 5
Pages: 627-639
Publication  
First Author: Teichert M
Year: 2017
Journal: Nat Commun
Title: Pericyte-expressed Tie2 controls angiogenesis and vessel maturation.
Volume: 8
Pages: 16106
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Horita K
Year: 1992
Journal: Biochem Biophys Res Commun
Title: A novel tyrosine kinase, hyk, expressed in murine embryonic stem cells.
Volume: 189
Issue: 3
Pages: 1747-53
Publication
First Author: Welford AF
Year: 2011
Journal: J Clin Invest
Title: TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice.
Volume: 121
Issue: 5
Pages: 1969-73
Publication  
First Author: Fadel BM
Year: 1998
Journal: Biochem J
Title: Functional analysis of the endothelial cell-specific Tie2/Tek promoter identifies unique protein-binding elements.
Volume: 330 ( Pt 1)
Pages: 335-43
Publication
First Author: Fadel BM
Year: 1999
Journal: J Biol Chem
Title: Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene.
Volume: 274
Issue: 29
Pages: 20376-83
Publication
First Author: Hamaguchi I
Year: 2006
Journal: Blood
Title: Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival.
Volume: 107
Issue: 3
Pages: 1207-13
Publication  
First Author: Peters KG
Year: 2004
Journal: Recent Prog Horm Res
Title: Functional significance of Tie2 signaling in the adult vasculature.
Volume: 59
Pages: 51-71
Publication
First Author: Boscolo E
Year: 2015
Journal: J Clin Invest
Title: Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.
Volume: 125
Issue: 9
Pages: 3491-504
Publication
First Author: Brickler TR
Year: 2018
Journal: J Neurosci
Title: Angiopoietin/Tie2 Axis Regulates the Age-at-Injury Cerebrovascular Response to Traumatic Brain Injury.
Volume: 38
Issue: 45
Pages: 9618-9634
Publication
First Author: Rasmussen AL
Year: 2014
Journal: Science
Title: Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.
Volume: 346
Issue: 6212
Pages: 987-91
Publication
First Author: Jongman RM
Year: 2019
Journal: Shock
Title: Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way.
Volume: 51
Issue: 6
Pages: 757-769
Publication
First Author: Ghosh CC
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Gene control of tyrosine kinase TIE2 and vascular manifestations of infections.
Volume: 113
Issue: 9
Pages: 2472-7
GXD Expression    
Probe: MGI:1303386
Assay Type: RT-PCR
Annotation Date: 1998-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1314623
Age: embryonic day 9.5
Image: 6
Specimen Label: Tie-2 +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1303386
Assay Type: RT-PCR
Annotation Date: 1998-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1314623
Age: embryonic day 9.5
Image: 6
Specimen Label: Tie-2 -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1329002
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1329058
Age: embryonic day 8.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1329002
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1329058
Age: embryonic day 8.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1329002
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1329058
Age: embryonic day 8.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Yolk sacs +/+ (RT+)
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Yolk sacs +/- (RT+)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Yolk sacs -/- (RT+)
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Embryos +/+ (RT+)
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Embryos +/- (RT+)
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1334605
Assay Type: RT-PCR
Annotation Date: 1999-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1334627
Age: embryonic day 9.5
Image: 2
Specimen Label: Embryos -/- (RT+)
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1929294
Assay Type: RT-PCR
Annotation Date: 2001-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1929453
Age: embryonic day 8.5
Image: 6
Specimen Label: +/- Tie2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1929294
Assay Type: RT-PCR
Annotation Date: 2001-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1929453
Age: embryonic day 8.5
Image: 6
Specimen Label: -/- Tie2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2651726
Assay Type: Western blot
Annotation Date: 2003-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:2651727
Age: embryonic day 10.0-11.0
Specimen Label: E heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1329002
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652236
Age: embryonic day 11.5
Specimen Label: +/- 20
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1329002
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652236
Age: embryonic day 11.5
Specimen Label: +/- 25
Detected: true
Specimen Num: 2