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Search results 1 to 100 out of 470 for Tet2

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Deplus R
Year: 2013
Journal: EMBO J
Title: TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
Volume: 32
Issue: 5
Pages: 645-55
Publication
First Author: Moran-Crusio K
Year: 2011
Journal: Cancer Cell
Title: Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Volume: 20
Issue: 1
Pages: 11-24
Publication
First Author: Chen Q
Year: 2013
Journal: Nature
Title: TET2 promotes histone O-GlcNAcylation during gene transcription.
Volume: 493
Issue: 7433
Pages: 561-4
Publication
First Author: Li Z
Year: 2011
Journal: Blood
Title: Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.
Volume: 118
Issue: 17
Pages: 4509-18
Publication
First Author: Dawlaty MM
Year: 2013
Journal: Dev Cell
Title: Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Volume: 24
Issue: 3
Pages: 310-23
Publication
First Author: Carrillo-Jimenez A
Year: 2019
Journal: Cell Rep
Title: TET2 Regulates the Neuroinflammatory Response in Microglia.
Volume: 29
Issue: 3
Pages: 697-713.e8
Publication
First Author: Carty SA
Year: 2018
Journal: J Immunol
Title: The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation.
Volume: 200
Issue: 1
Pages: 82-91
Publication  
First Author: Pan F
Year: 2017
Journal: Nat Commun
Title: Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Volume: 8
Pages: 15102
Publication
First Author: Shide K
Year: 2012
Journal: Leukemia
Title: TET2 is essential for survival and hematopoietic stem cell homeostasis.
Volume: 26
Issue: 10
Pages: 2216-23
Publication
First Author: Shen Q
Year: 2018
Journal: Nature
Title: Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation.
Volume: 554
Issue: 7690
Pages: 123-127
Publication
First Author: Kim MR
Year: 2020
Journal: Nat Commun
Title: TET2 directs mammary luminal cell differentiation and endocrine response.
Volume: 11
Issue: 1
Pages: 4642
Publication  
First Author: Inokura K
Year: 2017
Journal: Exp Hematol
Title: Impact of TET2 deficiency on iron metabolism in erythroblasts.
Volume: 49
Pages: 56-67.e5
Publication
First Author: Cimmino L
Year: 2017
Journal: Cell
Title: Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Volume: 170
Issue: 6
Pages: 1079-1095.e20
Publication
First Author: Costa Y
Year: 2013
Journal: Nature
Title: NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.
Volume: 495
Issue: 7441
Pages: 370-4
Publication
First Author: Fuster JJ
Year: 2017
Journal: Science
Title: Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.
Volume: 355
Issue: 6327
Pages: 842-847
Publication
First Author: Montagner S
Year: 2016
Journal: Cell Rep
Title: TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.
Volume: 15
Issue: 7
Pages: 1566-1579
Publication
First Author: Bejar R
Year: 2014
Journal: Blood
Title: TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
Volume: 124
Issue: 17
Pages: 2705-12
Publication
First Author: Wiehle L
Year: 2015
Journal: Mol Cell Biol
Title: Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.
Volume: 36
Issue: 3
Pages: 452-61
Publication
First Author: Ko M
Year: 2013
Journal: Nature
Title: Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Volume: 497
Issue: 7447
Pages: 122-6
Publication
First Author: Yue X
Year: 2019
Journal: Nat Commun
Title: Loss of TET2 and TET3 in regulatory T cells unleashes effector function.
Volume: 10
Issue: 1
Pages: 2011
Publication
First Author: Gontier G
Year: 2018
Journal: Cell Rep
Title: Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain.
Volume: 22
Issue: 8
Pages: 1974-1981
Publication
First Author: Kallin EM
Year: 2012
Journal: Mol Cell
Title: Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells.
Volume: 48
Issue: 2
Pages: 266-76
Publication  
First Author: Kunimoto H
Year: 2012
Journal: Sci Rep
Title: Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells.
Volume: 2
Pages: 273
Publication
First Author: Hon GC
Year: 2014
Journal: Mol Cell
Title: 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Volume: 56
Issue: 2
Pages: 286-97
Publication
First Author: Ito K
Year: 2019
Journal: Cell Rep
Title: Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis.
Volume: 28
Issue: 10
Pages: 2480-2490.e4
Publication
First Author: Zhang X
Year: 2016
Journal: Nat Genet
Title: DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
Volume: 48
Issue: 9
Pages: 1014-23
Publication
First Author: Zhang Q
Year: 2015
Journal: Nature
Title: Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
Volume: 525
Issue: 7569
Pages: 389-393
Publication  
First Author: Muto H
Year: 2014
Journal: Blood Cancer J
Title: Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice.
Volume: 4
Pages: e264
Publication
First Author: Zhao Z
Year: 2015
Journal: Cell Rep
Title: Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Volume: 13
Issue: 8
Pages: 1692-704
Publication
First Author: Huang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.
Volume: 111
Issue: 4
Pages: 1361-6
Publication
First Author: Sun J
Year: 2018
Journal: Cell Stem Cell
Title: SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function.
Volume: 23
Issue: 3
Pages: 355-369.e9
Publication
First Author: Wang Y
Year: 2015
Journal: Mol Cell
Title: WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Volume: 57
Issue: 4
Pages: 662-73
Publication
First Author: Koh KP
Year: 2011
Journal: Cell Stem Cell
Title: Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Volume: 8
Issue: 2
Pages: 200-13
Publication
First Author: Piccolo FM
Year: 2013
Journal: Mol Cell
Title: Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Volume: 49
Issue: 6
Pages: 1023-33
Publication
First Author: Tanaka S
Year: 2020
Journal: Nat Immunol
Title: Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.
Volume: 21
Issue: 8
Pages: 950-961
Publication
First Author: Pan W
Year: 2017
Journal: Immunity
Title: The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.
Volume: 47
Issue: 2
Pages: 284-297.e5
Publication
First Author: Kunimoto H
Year: 2018
Journal: Cancer Cell
Title: Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.
Volume: 33
Issue: 1
Pages: 44-59.e8
Publication    
First Author: Lio CW
Year: 2016
Journal: Elife
Title: Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.
Volume: 5
Publication
First Author: Quivoron C
Year: 2011
Journal: Cancer Cell
Title: TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Volume: 20
Issue: 1
Pages: 25-38
Publication
First Author: Dominguez PM
Year: 2018
Journal: Cancer Discov
Title: TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Volume: 8
Issue: 12
Pages: 1632-1653
Publication
First Author: Cai Z
Year: 2018
Journal: Cell Stem Cell
Title: Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Volume: 23
Issue: 6
Pages: 833-849.e5
Publication
First Author: Yang R
Year: 2018
Journal: Nat Commun
Title: Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.
Volume: 9
Issue: 1
Pages: 2143
Publication
First Author: Ichiyama K
Year: 2015
Journal: Immunity
Title: The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells.
Volume: 42
Issue: 4
Pages: 613-26
Publication
First Author: Jiang S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Dual mechanisms of posttranscriptional regulation of Tet2 by Let-7 microRNA in macrophages.
Volume: 116
Issue: 25
Pages: 12416-12421
Publication
First Author: Muto T
Year: 2013
Journal: J Exp Med
Title: Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.
Volume: 210
Issue: 12
Pages: 2627-39
Publication
First Author: Okashita N
Year: 2019
Journal: Sci Rep
Title: TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression.
Volume: 9
Issue: 1
Pages: 13462
Publication
First Author: Nair VS
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells.
Volume: 450
Issue: 1
Pages: 918-24
Publication
First Author: Rasmussen KD
Year: 2015
Journal: Genes Dev
Title: Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.
Volume: 29
Issue: 9
Pages: 910-22
Publication
First Author: Li L
Year: 2020
Journal: Hum Mol Genet
Title: Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Volume: 29
Issue: 11
Pages: 1833-1852
Publication
First Author: De Vita S
Year: 2014
Journal: PLoS One
Title: Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis.
Volume: 9
Issue: 5
Pages: e96209
Publication
First Author: Scourzic L
Year: 2016
Journal: Leukemia
Title: DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Volume: 30
Issue: 6
Pages: 1388-98
Publication
First Author: Chen E
Year: 2015
Journal: Blood
Title: Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms.
Volume: 125
Issue: 2
Pages: 327-35
Publication
First Author: Ko M
Year: 2010
Journal: Nature
Title: Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Volume: 468
Issue: 7325
Pages: 839-43
Publication
First Author: Hasegawa N
Year: 2017
Journal: Leukemia
Title: Impact of combinatorial dysfunctions of Tet2 and Ezh2 on the epigenome in the pathogenesis of myelodysplastic syndrome.
Volume: 31
Issue: 4
Pages: 861-871
Publication
First Author: Zhao Z
Year: 2016
Journal: Leukemia
Title: The catalytic activity of TET2 is essential for its myeloid malignancy-suppressive function in hematopoietic stem/progenitor cells.
Volume: 30
Issue: 8
Pages: 1784-1788
Publication
First Author: Ito S
Year: 2011
Journal: Science
Title: Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Volume: 333
Issue: 6047
Pages: 1300-3
Publication
First Author: Vella P
Year: 2013
Journal: Mol Cell
Title: Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.
Volume: 49
Issue: 4
Pages: 645-56
Publication
First Author: Ito S
Year: 2010
Journal: Nature
Title: Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Volume: 466
Issue: 7310
Pages: 1129-33
Publication
First Author: He YF
Year: 2011
Journal: Science
Title: Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Volume: 333
Issue: 6047
Pages: 1303-7
Publication
First Author: Tahiliani M
Year: 2009
Journal: Science
Title: Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Volume: 324
Issue: 5929
Pages: 930-5
Publication
First Author: Luchsinger LL
Year: 2019
Journal: Cell Stem Cell
Title: Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro.
Volume: 25
Issue: 2
Pages: 225-240.e7
Publication
First Author: Fuster JJ
Year: 2020
Journal: Cell Rep
Title: TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity.
Volume: 33
Issue: 4
Pages: 108326
Publication
First Author: Obeng EA
Year: 2016
Journal: Cancer Cell
Title: Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.
Volume: 30
Issue: 3
Pages: 404-417
Publication
First Author: Ko M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice.
Volume: 108
Issue: 35
Pages: 14566-71
Publication
First Author: Jing CB
Year: 2020
Journal: Leukemia
Title: Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors.
Volume: 34
Issue: 11
Pages: 2992-3006
Publication  
First Author: Zeng H
Year: 2019
Journal: Cancer Lett
Title: Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies.
Volume: 467
Pages: 1-8
Publication
First Author: Shih AH
Year: 2015
Journal: Cancer Cell
Title: Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Volume: 27
Issue: 4
Pages: 502-15
Publication
First Author: Cortes JR
Year: 2018
Journal: Cancer Cell
Title: RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.
Volume: 33
Issue: 2
Pages: 259-273.e7
Publication
First Author: Viaud M
Year: 2020
Journal: Cell Rep
Title: ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Volume: 30
Issue: 10
Pages: 3397-3410.e5
Publication
First Author: Sardina JL
Year: 2018
Journal: Cell Stem Cell
Title: Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Volume: 23
Issue: 5
Pages: 727-741.e9
Publication
First Author: Cheng Y
Year: 2018
Journal: Cell Rep
Title: Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.
Volume: 25
Issue: 11
Pages: 3194-3203.e4
Publication
First Author: Zhang H
Year: 2019
Journal: Nat Commun
Title: Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.
Volume: 10
Issue: 1
Pages: 244
Publication  
First Author: Balasubramani A
Year: 2015
Journal: Nat Commun
Title: Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.
Volume: 6
Pages: 7307
Publication  
First Author: Li X
Year: 2017
Journal: Nat Commun
Title: Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis.
Volume: 8
Pages: 15903
Publication
First Author: Xue JH
Year: 2016
Journal: J Biol Chem
Title: Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation.
Volume: 291
Issue: 2
Pages: 731-8
Publication
First Author: Cai Z
Year: 2020
Journal: Cell Rep
Title: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Volume: 31
Issue: 12
Pages: 107816
Publication
First Author: Tsagaratou A
Year: 2017
Journal: Nat Immunol
Title: TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.
Volume: 18
Issue: 1
Pages: 45-53
Publication
First Author: Kubota S
Year: 2019
Journal: Nat Commun
Title: Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Volume: 10
Issue: 1
Pages: 1653
Publication
First Author: Wang H
Year: 2013
Journal: Cell
Title: One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Volume: 153
Issue: 4
Pages: 910-8
Publication
First Author: Yang J
Year: 2016
Journal: Cell Rep
Title: Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs.
Volume: 15
Issue: 8
Pages: 1809-21
Publication
First Author: Ravichandran M
Year: 2019
Journal: Cell Rep
Title: Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.
Volume: 28
Issue: 8
Pages: 1993-2003.e5
Publication
First Author: Inoue S
Year: 2016
Journal: Cancer Cell
Title: Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
Volume: 30
Issue: 2
Pages: 337-348
Publication
First Author: Khoueiry R
Year: 2017
Journal: Nat Genet
Title: Lineage-specific functions of TET1 in the postimplantation mouse embryo.
Volume: 49
Issue: 7
Pages: 1061-1072
Publication
First Author: Fang S
Year: 2019
Journal: Nat Commun
Title: Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development.
Volume: 10
Issue: 1
Pages: 4297
Publication
First Author: Meisel M
Year: 2018
Journal: Nature
Title: Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Volume: 557
Issue: 7706
Pages: 580-584
Publication
First Author: Mouly E
Year: 2018
Journal: Blood Adv
Title: B-cell tumor development in Tet2-deficient mice.
Volume: 2
Issue: 6
Pages: 703-714
Publication
First Author: Wang Q
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A mosaic analysis system with Cre or Tomato expression in the mouse.
Volume: 117
Issue: 45
Pages: 28212-28220
Publication
First Author: Tara S
Year: 2018
Journal: Blood
Title: Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.
Volume: 132
Issue: 23
Pages: 2470-2483
Publication
First Author: Yang R
Year: 2015
Journal: Immunity
Title: Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.
Volume: 43
Issue: 2
Pages: 251-63
Publication
First Author: Nakatsukasa H
Year: 2019
Journal: Int Immunol
Title: Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.
Volume: 31
Issue: 5
Pages: 335-347
Publication
First Author: Kunimoto H
Year: 2017
Journal: Blood
Title: Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells.
Volume: 129
Issue: 13
Pages: 1779-1790
Publication
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
Publication
First Author: Chen H
Year: 2014
Journal: Nucleic Acids Res
Title: Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.
Volume: 42
Issue: 3
Pages: 1563-74
Publication
First Author: Joshi SR
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Volume: 318
Issue: 4
Pages: L773-L786
Publication
First Author: Bonvin E
Year: 2019
Journal: Cancer Res
Title: TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
Volume: 79
Issue: 3
Pages: 482-494