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Search results 1 to 100 out of 519 for Tfam

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Type Details Score
Gene
7019 | TFAM
Type: gene
Organism: human
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Gene
510059 | TFAM
Type: gene
Organism: cattle
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Gene
373888 | TFAM
Type: gene
Organism: chicken
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Gene
571106 | tfam
Type: gene
Organism: zebrafish
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Gene
701368 | TFAM
Type: gene
Organism: macaque, rhesus
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Gene
100135718 | tfam
Type: gene
Organism: frog, western clawed
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Gene
83474 | Tfam
Type: gene
Organism: rat
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Gene
488989 | TFAM
Type: gene
Organism: dog, domestic
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Gene
466079 | TFAM
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:107810 | Tfam
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33760663 | J:316342
First Author: Ghazal N
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: Mitochondrial functional resilience after TFAM ablation in the adult heart.
Volume: 320
Issue: 6
Pages: C929-C942
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Publication
11668394 | J:71895
First Author: Rantanen A
Year: 2001
Journal: Mamm Genome
Title: Downregulation of Tfam and mtDNA copy number during mammalian spermatogenesis.
Volume: 12
Issue: 10
Pages: 787-92
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GXD Expression
GXD Expression
   
Probe: MGI:7447504
Assay Type: RNA in situ
Annotation Date: 2023-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1910424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7448495
Age: embryonic day 16.5
Note: Expression not described.
Specimen Label: 2b Tfam CTL
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7447504
Assay Type: RNA in situ
Annotation Date: 2023-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1910424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7448495
Age: embryonic day 16.5
Note: Expression not described.
Specimen Label: 2b Tfam cKO
Specimen Num: 2
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Publication
36049540 | J:329338
     
First Author: Zhang J
Year: 2022
Journal: J Invest Dermatol
Title: TFAM Deficiency‒Mediated Mitochondrial Disorder Affects Langerhans Cell Maintenance and Function.
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Publication
30553768 | J:277612
 
First Author: Theilen NT
Year: 2019
Journal: Arch Biochem Biophys
Title: TFAM overexpression diminishes skeletal muscle atrophy after hindlimb suspension in mice.
Volume: 666
Pages: 138-147
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Publication
34462320 | J:312991
 
First Author: Bonekamp NA
Year: 2021
Journal: Life Sci Alliance
Title: High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.
Volume: 4
Issue: 11
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Publication
23168219 | J:194082
First Author: Vernochet C
Year: 2012
Journal: Cell Metab
Title: Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.
Volume: 16
Issue: 6
Pages: 765-76
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Publication
26305956 | J:226810
First Author: Kukat C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Volume: 112
Issue: 36
Pages: 11288-93
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Publication
17581862 | J:128294
First Author: Kaufman BA
Year: 2007
Journal: Mol Biol Cell
Title: The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.
Volume: 18
Issue: 9
Pages: 3225-36
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Publication
29684311 | J:263836
First Author: Srivillibhuthur M
Year: 2018
Journal: Dev Biol
Title: TFAM is required for maturation of the fetal and adult intestinal epithelium.
Volume: 439
Issue: 2
Pages: 92-101
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Publication
32971400 | J:297799
 
First Author: Dai XG
Year: 2020
Journal: Mol Immunol
Title: The interaction between C/EBPβ and TFAM promotes acute kidney injury via regulating NLRP3 inflammasome-mediated pyroptosis.
Volume: 127
Pages: 136-145
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Publication
35947192 | J:334015
First Author: Yoshioka H
Year: 2022
Journal: J Bone Miner Metab
Title: Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures.
Volume: 40
Issue: 5
Pages: 839-852
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191459
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tfam
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191459
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tfam
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191459
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tfam
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191459
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tfam
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191459
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tfam
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191459
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tfam
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6185022
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191459
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tfam
Detected: true
Specimen Num: 7
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HT Experiment
GSE98579 | RNAseq for Tfam knock under NKX2.5 promoter
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11171100 | J:67897
First Author: Goto A
Year: 2001
Journal: Biochem J
Title: Drosophila mitochondrial transcription factor A (d-TFAM) is dispensable for the transcription of mitochondrial DNA in Kc167 cells.
Volume: 354
Issue: Pt 2
Pages: 243-8
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Publication
30949583 | J:283036
First Author: Filograna R
Year: 2019
Journal: Sci Adv
Title: Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse.
Volume: 5
Issue: 4
Pages: eaav9824
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Publication
9916807 | J:51964
First Author: Wang J
Year: 1999
Journal: Nat Genet
Title: Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.
Volume: 21
Issue: 1
Pages: 133-7
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Publication
26374844 | J:226485
First Author: Gineste C
Year: 2015
Journal: Hum Mol Genet
Title: Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.
Volume: 24
Issue: 23
Pages: 6580-7
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Publication
37872380 | J:342034
First Author: Olkhova EA
Year: 2023
Journal: Commun Biol
Title: A novel mouse model of mitochondrial disease exhibits juvenile-onset severe neurological impairment due to parvalbumin cell mitochondrial dysfunction.
Volume: 6
Issue: 1
Pages: 1078
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Publication
34294718 | J:321203
First Author: Fu Z
Year: 2021
Journal: Nat Commun
Title: Mitochondrial transcription factor A in RORÎłt+ lymphocytes regulate small intestine homeostasis and metabolism.
Volume: 12
Issue: 1
Pages: 4462
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Publication
34320035 | J:308318
First Author: Kuroda R
Year: 2021
Journal: PLoS One
Title: Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo.
Volume: 16
Issue: 7
Pages: e0255355
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Publication
28962857 | J:253735
 
First Author: Sommakia S
Year: 2017
Journal: J Mol Cell Cardiol
Title: Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium.
Volume: 113
Pages: 22-32
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Publication
25005176 | J:217570
First Author: Vernochet C
Year: 2014
Journal: FASEB J
Title: Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications.
Volume: 28
Issue: 10
Pages: 4408-19
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Publication
25642965 | J:220373
First Author: West AP
Year: 2015
Journal: Nature
Title: Mitochondrial DNA stress primes the antiviral innate immune response.
Volume: 520
Issue: 7548
Pages: 553-7
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Publication
15016765 | J:90369
First Author: Ekstrand MI
Year: 2004
Journal: Hum Mol Genet
Title: Mitochondrial transcription factor A regulates mtDNA copy number in mammals.
Volume: 13
Issue: 9
Pages: 935-44
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Publication
20566479 | J:302965
First Author: Freyer C
Year: 2010
Journal: Nucleic Acids Res
Title: Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription.
Volume: 38
Issue: 19
Pages: 6577-88
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Publication
15757973 | J:97995
First Author: Tavi P
Year: 2005
Journal: Hum Mol Genet
Title: Abnormal Ca(2+) release and catecholamine-induced arrhythmias in mitochondrial cardiomyopathy.
Volume: 14
Issue: 8
Pages: 1069-76
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Publication
16043643 | J:117495
First Author: Ikeuchi M
Year: 2005
Journal: Circulation
Title: Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction.
Volume: 112
Issue: 5
Pages: 683-90
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Publication
25944881 | J:225852
First Author: Chandrasekaran K
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy.
Volume: 309
Issue: 2
Pages: E132-41
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Publication
26545237 | J:244838
First Author: Brown TA
Year: 2015
Journal: PLoS One
Title: Mitochondrial Transcription Factor A (TFAM) Binds to RNA Containing 4-Way Junctions and Mitochondrial tRNA.
Volume: 10
Issue: 11
Pages: e0142436
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Publication
27068470 | J:235179
First Author: Hamanaka RB
Year: 2016
Journal: Cell Rep
Title: The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.
Volume: 15
Issue: 3
Pages: 451-459
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Publication
9500544 | J:46387
First Author: Larsson NG
Year: 1998
Journal: Nat Genet
Title: Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
Volume: 18
Issue: 3
Pages: 231-6
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Publication
12206900 | J:311494
First Author: Silva JP
Year: 2002
Journal: Biochim Biophys Acta
Title: Manipulation of mitochondrial DNA gene expression in the mouse.
Volume: 1555
Issue: 1-3
Pages: 106-10
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Publication
22482729 | J:184460
First Author: Garedew A
Year: 2012
Journal: Cell Metab
Title: Mitochondrial dynamics, biogenesis, and function are coordinated with the cell cycle by APC/C CDH1.
Volume: 15
Issue: 4
Pages: 466-79
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Publication
18945718 | J:144636
First Author: Aydin J
Year: 2009
Journal: Hum Mol Genet
Title: Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy.
Volume: 18
Issue: 2
Pages: 278-88
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Publication
34312668 | J:309556
 
First Author: Del Rey MJ
Year: 2021
Journal: Dis Model Mech
Title: TFAM-deficient mouse skin fibroblasts - an ex vivo model of mitochondrial dysfunction.
Volume: 14
Issue: 8
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Publication
35165165 | J:322723
First Author: Gao X
Year: 2022
Journal: J Immunol
Title: TFAM-Dependent Mitochondrial Metabolism Is Required for Alveolar Macrophage Maintenance and Homeostasis.
Volume: 208
Issue: 6
Pages: 1456-1466
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Publication
34378772 | J:309759
 
First Author: Chatel B
Year: 2021
Journal: Dis Model Mech
Title: Impaired aerobic capacity and premature fatigue preceding muscle weakness in the skeletal muscle Tfam-knockout mouse model.
Volume: 14
Issue: 9
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Publication
31269437 | J:281871
First Author: Fu Z
Year: 2019
Journal: Cell Rep
Title: Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Volume: 28
Issue: 1
Pages: 159-171.e4
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Publication
28504707 | J:249680
First Author: Liu X
Year: 2017
Journal: Nat Cell Biol
Title: Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation.
Volume: 19
Issue: 6
Pages: 626-638
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Publication
20130269 | J:161982
First Author: Wai T
Year: 2010
Journal: Biol Reprod
Title: The role of mitochondrial DNA copy number in mammalian fertility.
Volume: 83
Issue: 1
Pages: 52-62
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Publication
10737799 | J:61372
First Author: Li H
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy.
Volume: 97
Issue: 7
Pages: 3467-72
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Publication
20002202 | J:170052
First Author: Galter D
Year: 2010
Journal: Genes Brain Behav
Title: MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease.
Volume: 9
Issue: 2
Pages: 173-81
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Publication
31226324 | J:302843
 
First Author: Lai JH
Year: 2019
Journal: Brain Res
Title: Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease.
Volume: 1720
Pages: 146301
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Publication
17003040 | J:117614
First Author: Duvezin-Caubet S
Year: 2006
Journal: J Biol Chem
Title: Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology.
Volume: 281
Issue: 49
Pages: 37972-9
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Publication
30659235 | J:302839
First Author: Wen YA
Year: 2019
Journal: Cell Death Differ
Title: The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer.
Volume: 26
Issue: 10
Pages: 1955-1969
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Publication
36738738 | J:334954
First Author: Wculek SK
Year: 2023
Journal: Immunity
Title: Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis.
Volume: 56
Issue: 3
Pages: 516-530.e9
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Publication
22056359 | J:180188
First Author: Woo DK
Year: 2012
Journal: Am J Pathol
Title: Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.
Volume: 180
Issue: 1
Pages: 24-31
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Publication
37095377 | J:337624
First Author: Yazicioglu YF
Year: 2023
Journal: Nat Immunol
Title: Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis.
Volume: 24
Issue: 6
Pages: 991-1006
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Publication
28595911 | J:302938
 
First Author: Langley MR
Year: 2018
Journal: Neurotoxicology
Title: Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.
Volume: 64
Pages: 240-255
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Publication
23690562 | J:212139
First Author: Saleem A
Year: 2013
Journal: J Physiol
Title: Acute exercise induces tumour suppressor protein p53 translocation to the mitochondria and promotes a p53-Tfam-mitochondrial DNA complex in skeletal muscle.
Volume: 591
Issue: 14
Pages: 3625-36
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Publication
30226866 | J:266199
First Author: Huang S
Year: 2018
Journal: PLoS Biol
Title: Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.
Volume: 16
Issue: 9
Pages: e2005233
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Publication
23386745 | J:213840
First Author: Hamanaka RB
Year: 2013
Journal: Sci Signal
Title: Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development.
Volume: 6
Issue: 261
Pages: ra8
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Publication
33264655 | J:305495
 
First Author: Chen M
Year: 2021
Journal: Exp Eye Res
Title: An efficient inducible RPE-Selective cre transgenic mouse line.
Volume: 202
Pages: 108370
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Publication
33709773 | J:320865
First Author: Oller J
Year: 2021
Journal: Circulation
Title: Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.
Volume: 143
Issue: 21
Pages: 2091-2109
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Publication
11259653 | J:125471
First Author: Wang J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression.
Volume: 98
Issue: 7
Pages: 4038-43
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Publication
29021295 | J:290535
First Author: Zhang D
Year: 2018
Journal: Circ Res
Title: Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation.
Volume: 122
Issue: 1
Pages: 74-87
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Publication
16202542 | J:103542
 
First Author: D'Errico I
Year: 2005
Journal: Gene
Title: History of the Tfam gene in primates.
Volume: 362
Pages: 125-32
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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Publication
35293971 | J:331835
First Author: Salazar-Petres E
Year: 2022
Journal: Biol Reprod
Title: Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice†.
Volume: 106
Issue: 6
Pages: 1292-1311
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Protein Coding Gene
MGP_CAROLIEiJ_G0015427 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017279 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017075 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030843 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016240 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8673128 | J:33733
First Author: Larsson NG
Year: 1996
Journal: Nat Genet
Title: A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein.
Volume: 13
Issue: 3
Pages: 296-302
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Publication
28111078 | J:256033
First Author: Beckervordersandforth R
Year: 2017
Journal: Neuron
Title: Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.
Volume: 93
Issue: 3
Pages: 560-573.e6
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Publication
32439659 | J:290821
First Author: DesdĂ­n-MicĂł G
Year: 2020
Journal: Science
Title: T cells with dysfunctional mitochondria induce multimorbidity and premature senescence.
Volume: 368
Issue: 6497
Pages: 1371-1376
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Publication
28867657 | J:259380
First Author: Weiland D
Year: 2018
Journal: J Invest Dermatol
Title: Imbalance of Mitochondrial Respiratory Chain Complexes in the Epidermis Induces Severe Skin Inflammation.
Volume: 138
Issue: 1
Pages: 132-140
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