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Search results 1 to 83 out of 83 for Tfb1m

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
51106 | TFB1M
Type: gene
Organism: human
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Gene
549248 | tfb1m
Type: gene
Organism: frog, western clawed
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Gene
112204084 | TFB1M
Type: gene
Organism: chimpanzee
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Gene
308140 | Tfb1m
Type: gene
Organism: rat
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Gene
476253 | TFB1M
Type: gene
Organism: dog, domestic
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Gene
533438 | TFB1M
Type: gene
Organism: cattle
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Gene
428608 | TFB1M
Type: gene
Organism: chicken
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Gene
767802 | tfb1m
Type: gene
Organism: zebrafish
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Gene
701830 | TFB1M
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2146851 | Tfb1m
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24916378 | J:214733
First Author: Sharoyko VV
Year: 2014
Journal: Hum Mol Genet
Title: Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.
Volume: 23
Issue: 21
Pages: 5733-49
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Publication
21195351 | J:303121
First Author: Koeck T
Year: 2011
Journal: Cell Metab
Title: A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
Volume: 13
Issue: 1
Pages: 80-91
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Publication
26464487 | J:226981
First Author: Lee S
Year: 2015
Journal: Hum Mol Genet
Title: Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing.
Volume: 24
Issue: 25
Pages: 7286-94
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Publication
23804760 | J:354322
First Author: Guja KE
Year: 2013
Journal: Nucleic Acids Res
Title: Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1.
Volume: 41
Issue: 16
Pages: 7947-59
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Publication
19356719 | J:148166
First Author: Metodiev MD
Year: 2009
Journal: Cell Metab
Title: Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome.
Volume: 9
Issue: 4
Pages: 386-97
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Publication
12532263 | J:81452
First Author: Rantanen A
Year: 2003
Journal: Mamm Genome
Title: Characterization of the mouse genes for mitochondrial transcription factors B1 and B2.
Volume: 14
Issue: 1
Pages: 1-6
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Protein Coding Gene
MGP_CAROLIEiJ_G0021018 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023036 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022831 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2146851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022908 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022095 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023336 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021923 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:3654357
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3654434
Age: embryonic day 1.5
Image: 4
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3654357
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3654434
Age: embryonic day 2.5
Image: 4
Specimen Label: 8-cell
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3654357
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3654434
Age: embryonic day 3.0
Image: 4
Specimen Label: Mor
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3654357
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3654434
Age: embryonic day 3.5
Image: 4
Specimen Label: Blasto
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3654357
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3654434
Age: postnatal
Image: 4
Specimen Label: Oocyte
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7738601
Assay Type: RT-PCR
Annotation Date: 2024-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7750806
Age: postnatal week 4
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7738601
Assay Type: RT-PCR
Annotation Date: 2024-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7750806
Age: postnatal week 4
Specimen Label: Chd4
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7738601
Assay Type: RT-PCR
Annotation Date: 2024-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7750843
Age: postnatal week 4
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7738601
Assay Type: RT-PCR
Annotation Date: 2024-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7750843
Age: postnatal week 4
Specimen Label: Chd4
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:905305
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516943
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
15895466 | J:99438
First Author: Thundathil J
Year: 2005
Journal: Mol Reprod Dev
Title: Molecular control of mitochondrial function in preimplantation mouse embryos.
Volume: 71
Issue: 4
Pages: 405-13
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Publication
35081489 | J:319888
 
First Author: Son JS
Year: 2022
Journal: EBioMedicine
Title: Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Volume: 76
Pages: 103842
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Publication
27166947 | J:235368
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
12068295 | -
First Author: Falkenberg M
Year: 2002
Journal: Nat Genet
Title: Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.
Volume: 31
Issue: 3
Pages: 289-94
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Publication
19417006 | -
First Author: Cotney J
Year: 2009
Journal: Hum Mol Genet
Title: Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness.
Volume: 18
Issue: 14
Pages: 2670-82
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Publication
16533820 | -
First Author: Shutt TE
Year: 2006
Journal: Mol Biol Evol
Title: Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont.
Volume: 23
Issue: 6
Pages: 1169-79
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Protein Domain
IPR016861 | TFB2M
Type: Family
Description: rRNA methyltransferase-related mitochondrial transcription factors B1 (TFB1M) and B2 (TFB2M) perform unique, yet cooperative functions. In addition to being mitochondrial transcription factors, they can dimethylate two adjacent adenines in a stem-loop structure close to the 3' end of the small subunit rRNA, a modification that is highly conserved in nature [, ]. The primary function of TFB2 is mtDNA transcription and maintenance, which is independent of its rRNA methyltransferase activity, while that of TFB1M is mitochondrial rRNA methylation []. TFB1M and TFB2M. This family represents TFB2M. Compared to TFB1M, TFB2M activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity [].
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Publication
24958105 | J:224266
First Author: Yang ZF
Year: 2014
Journal: Mol Cell Biol
Title: GABP transcription factor (nuclear respiratory factor 2) is required for mitochondrial biogenesis.
Volume: 34
Issue: 17
Pages: 3194-201
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Publication
26552864 | J:228068
First Author: McKay SE
Year: 2015
Journal: Am J Pathol
Title: Auditory Pathology in a Transgenic mtTFB1 Mouse Model of Mitochondrial Deafness.
Volume: 185
Issue: 12
Pages: 3132-40
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Protein
Q3TL26
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
B2RSE6
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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