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Search results 1 to 100 out of 131 for Tfg

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: TFG (TRK-fused gene) is localised at endoplasmic reticulum (ER) exit sites and modulates ER export []. It may function at the ER/ERGIC interface to locally concentrate COPII-coated transport carriers and link exit sites on the ER to ERGIC membranes []. It is also an inhibitory regulator of the ubiquitin-proteasome system [, ]. Mutations in the TFG gene cause Okinawa hereditary motor and sensory neuropathy (HMSNO) []and spastic paraplegia 57, autosomal recessive (SPG57) [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Johnson A
Year: 2015
Journal: EMBO J
Title: TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization.
Volume: 34
Issue: 6
Pages: 811-27
Publication
First Author: Beetz C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.
Volume: 110
Issue: 13
Pages: 5091-6
Protein
Organism: Mus musculus
Length: 220  
Fragment?: true
Publication
First Author: Ishiura H
Year: 2012
Journal: Am J Hum Genet
Title: The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement.
Volume: 91
Issue: 2
Pages: 320-9
Publication
First Author: Kanadome T
Year: 2017
Journal: FEBS J
Title: The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein.
Volume: 284
Issue: 1
Pages: 56-76
Publication
First Author: Mencinger M
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Characterization of TFG in mus musculus and Caenorhabditis elegans.
Volume: 257
Issue: 1
Pages: 67-73
Publication  
First Author: Yagi T
Year: 2014
Journal: Neurobiol Dis
Title: Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system.
Volume: 66
Pages: 83-91
Protein
Organism: Mus musculus
Length: 397  
Fragment?: false
Protein
Organism: Mus musculus
Length: 103  
Fragment?: true
Protein
Organism: Mus musculus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus
Length: 131  
Fragment?: true
Protein
Organism: Mus musculus
Length: 89  
Fragment?: true
Protein
Organism: Mus musculus
Length: 389  
Fragment?: false
Publication
First Author: Yamamotoya T
Year: 2017
Journal: Sci Rep
Title: Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.
Volume: 7
Issue: 1
Pages: 13026
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3604358
Age: embryonic day 7.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3604358
Age: embryonic day 11.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3604358
Age: embryonic day 15.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3604358
Age: embryonic day 17.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Note: Expression is present in the upper, but not the lower, cortical plate.
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666818
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Note: Expression was detected in limb buds, branchial arches, nasal processes and brain. Staining was weak in the primitive spinal cord and the dorsal root ganglia. Other organs appeared negative.
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609218
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1611718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1668018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
Publication
First Author: Sima J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.
Volume: 115
Issue: 32
Pages: 8173-8178
Publication
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
Publication
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
UniProt Feature
Begin: 379
Description: TFG box
Type: short sequence motif
End: 399
UniProt Feature
Begin: 330
Description: TFG box
Type: short sequence motif
End: 350
UniProt Feature
Begin: 102
Description: TFG box
Type: short sequence motif
End: 122
UniProt Feature
Begin: 41
Description: TFG box
Type: short sequence motif
End: 61
UniProt Feature
Begin: 185
Description: TFG box
Type: short sequence motif
End: 205
UniProt Feature
Begin: 250
Description: TFG box
Type: short sequence motif
End: 270
Protein Domain
Type: Domain
Description: Sm and Sm-like proteins of the RNA-binding Lsm (like Sm) domain family arefound in all domains of life and are generally involved in important RNA-processing tasks. Lsm13-16 homologues share a domain organisation consisting ofa divergent N-terminal Lsm domain and a central or C-terminal consensus motifDFDF-x(7)-F. In few other sequences, the DFDF box is replaced by a DYDF or EFDF box [].The FFD box and TFG box are two other strongly conserved sequence motifs(Y-x-K-x(3)-FFD-x-[IL]-S and [RKH]-x(2,5)-E-x(0-2)-[RK]-x(3,4)-[DE]-TFG respectively) contained in Lsm13-15, but not Lsm16, homologues. They succeed the DFDF-x(7)-F motif and are also predicted to be of helical nature [].This entry represents the TGF box.
Protein
Organism: Mus musculus
Length: 124  
Fragment?: true
Protein
Organism: Mus musculus
Length: 157  
Fragment?: true
Protein
Organism: Mus musculus
Length: 240  
Fragment?: false
Protein
Organism: Mus musculus
Length: 305  
Fragment?: false
Publication
First Author: Greco A
Year: 1998
Journal: Oncogene
Title: Role of the TFG N-terminus and coiled-coil domain in the transforming activity of the thyroid TRK-T3 oncogene.
Volume: 16
Issue: 6
Pages: 809-16
DO Term
Protein
Organism: Mus musculus
Length: 462  
Fragment?: false
Protein
Organism: Mus musculus
Length: 385  
Fragment?: false
Publication
First Author: Albrecht M
Year: 2004
Journal: FEBS Lett
Title: Novel Sm-like proteins with long C-terminal tails and associated methyltransferases.
Volume: 569
Issue: 1-3
Pages: 18-26
Allele
Name: transgene insertion IH44, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Publication categories: ProxyCollection
Strain
Attribute String: mutant stock, transgenic