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Search results 1 to 100 out of 142 for Tfg

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: pig, domestic
Protein Domain
Type: Family
Description: TFG (TRK-fused gene) is localised at endoplasmic reticulum (ER) exit sites and modulates ER export []. It may function at the ER/ERGIC interface to locally concentrate COPII-coated transport carriers and link exit sites on the ER to ERGIC membranes []. It is also an inhibitory regulator of the ubiquitin-proteasome system [, ]. Mutations in the TFG gene cause Okinawa hereditary motor and sensory neuropathy (HMSNO) []and spastic paraplegia 57, autosomal recessive (SPG57) [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Beetz C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.
Volume: 110
Issue: 13
Pages: 5091-6
Publication
First Author: Johnson A
Year: 2015
Journal: EMBO J
Title: TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization.
Volume: 34
Issue: 6
Pages: 811-27
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
Publication
First Author: Ishiura H
Year: 2012
Journal: Am J Hum Genet
Title: The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement.
Volume: 91
Issue: 2
Pages: 320-9
Publication
First Author: Kanadome T
Year: 2017
Journal: FEBS J
Title: The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein.
Volume: 284
Issue: 1
Pages: 56-76
Publication
First Author: Mencinger M
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Characterization of TFG in mus musculus and Caenorhabditis elegans.
Volume: 257
Issue: 1
Pages: 67-73
Publication  
First Author: Yagi T
Year: 2014
Journal: Neurobiol Dis
Title: Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system.
Volume: 66
Pages: 83-91
GXD Expression    
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Specimen Label: Table S5 - Tfg
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Specimen Label: Table S5 - Tfg
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:1513028
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4354860
Age: embryonic day 14.5
Note: Expression is present in the upper, but not the lower, cortical plate.
Specimen Label: Table S5 - Tfg
Detected: true
Specimen Num: 1
Protein
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
Publication
First Author: Yamamotoya T
Year: 2017
Journal: Sci Rep
Title: Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.
Volume: 7
Issue: 1
Pages: 13026
Gene
Type: gene
Organism: macaque, rhesus
Publication
First Author: Yamamotoya T
Year: 2022
Journal: Sci Rep
Title: Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases.
Volume: 12
Issue: 1
Pages: 1966
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3604358
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3604358
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3604358
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3604359
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3604358
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666818
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Note: Expression was detected in limb buds, branchial arches, nasal processes and brain. Staining was weak in the primitive spinal cord and the dorsal root ganglia. Other organs appeared negative.
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609218
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1611718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:228812
Assay Type: RNA in situ
Annotation Date: 2005-11-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1668018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3604362
Age: embryonic day 10.5
Specimen Label: 4b
Detected: true
Specimen Num: 1
Publication
First Author: Sima J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.
Volume: 115
Issue: 32
Pages: 8173-8178
Publication
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
Publication
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 379
Description: TFG box
Type: short sequence motif
End: 399
UniProt Feature
Begin: 330
Description: TFG box
Type: short sequence motif
End: 350
UniProt Feature
Begin: 102
Description: TFG box
Type: short sequence motif
End: 122
UniProt Feature
Begin: 250
Description: TFG box
Type: short sequence motif
End: 270
UniProt Feature
Begin: 185
Description: TFG box
Type: short sequence motif
End: 205
UniProt Feature
Begin: 41
Description: TFG box
Type: short sequence motif
End: 61
Protein Domain
Type: Domain
Description: Sm and Sm-like proteins of the RNA-binding Lsm (like Sm) domain family arefound in all domains of life and are generally involved in important RNA-processing tasks. Lsm13-16 homologues share a domain organisation consisting ofa divergent N-terminal Lsm domain and a central or C-terminal consensus motifDFDF-x(7)-F. In few other sequences, the DFDF box is replaced by a DYDF or EFDF box [].The FFD box and TFG box are two other strongly conserved sequence motifs(Y-x-K-x(3)-FFD-x-[IL]-S and [RKH]-x(2,5)-E-x(0-2)-[RK]-x(3,4)-[DE]-TFG respectively) contained in Lsm13-15, but not Lsm16, homologues. They succeed the DFDF-x(7)-F motif and are also predicted to be of helical nature [].This entry represents the TGF box.
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true