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Search results 1 to 97 out of 97 for Tfpi2

0.029s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Tissue factor pathway inhibitor 2 (TFPI-2), also known as matrix serine protease inhibitor or placental protein 5, contains the characteristic three Kunitz domains with short spacer sequences present in TFPI-1 []. It has inhibitory activity towards trypsin, plasmin, and factor VIIa/tissue factor through its Kunitz domain 1 (KD1) [, ]. Because of its association with the extracellular matrix, TFPI-2 is predicted to play a major role in extracellular matrix remodelling and turnover []. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis and tumour growth/metastasis [, ].
Publication
First Author: Miyagi Y
Year: 1996
Journal: DNA Cell Biol
Title: Cloning of the cDNA encoding mouse PP5/TFPI-2 and mapping of the gene to chromosome 6.
Volume: 15
Issue: 11
Pages: 947-54
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
Publication
First Author: Chand HS
Year: 2005
Journal: Thromb Haemost
Title: Structure, function and biology of tissue factor pathway inhibitor-2.
Volume: 94
Issue: 6
Pages: 1122-30
Publication
First Author: Chand HS
Year: 2004
Journal: J Biol Chem
Title: Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2.
Volume: 279
Issue: 17
Pages: 17500-7
Publication
First Author: Rao CN
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor.
Volume: 255
Issue: 1
Pages: 94-8
Publication
First Author: Rao CN
Year: 1996
Journal: Arch Biochem Biophys
Title: Extracellular matrix-associated serine protease inhibitors (Mr 33,000, 31,000, and 27,000) are single-gene products with differential glycosylation: cDNA cloning of the 33-kDa inhibitor reveals its identity to tissue factor pathway inhibitor-2.
Volume: 335
Issue: 1
Pages: 82-92
Publication
First Author: Ferraresso S
Year: 2014
Journal: PLoS One
Title: Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma.
Volume: 9
Issue: 4
Pages: e92707
Publication
First Author: Monk D
Year: 2008
Journal: Genome Res
Title: Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing.
Volume: 18
Issue: 8
Pages: 1270-81
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Ali MN
Year: 2018
Journal: Front Immunol
Title: TFPI-2 Protects Against Gram-Negative Bacterial Infection.
Volume: 9
Pages: 2072
Publication
First Author: Chaudhuri M
Year: 2001
Journal: Gene
Title: Cloning and characterization of a novel serine/threonine protein phosphatase type 5 from Trypanosoma brucei.
Volume: 266
Issue: 1-2
Pages: 1-13
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2655726
Age: embryonic day 10.0
Specimen Label: day 10 placenta
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2655726
Age: postnatal adult
Specimen Label: day 10 uterus
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:2655726
Age: embryonic day 10.0
Specimen Label: day 10 whole embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2655726
Age: embryonic day 16.0
Specimen Label: day 16 placenta
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2655726
Age: postnatal adult
Specimen Label: day 16 uterus
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185824
Stage: TS24
Assay Id: MGI:2655726
Age: embryonic day 16.0
Specimen Label: day 16 head of embryo
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640524
Stage: TS24
Assay Id: MGI:2655726
Age: embryonic day 16.0
Specimen Label: day 16 body trunk and extremities
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185724
Stage: TS24
Assay Id: MGI:2655726
Age: embryonic day 16.0
Specimen Label: day 16 body trunk and extremities
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression        
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Not Specified
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 7
Specimen Num: 7
GXD Expression      
Probe: MGI:34453
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2655727
Age: postnatal week 10
Specimen Label: 8
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:5927588
Assay Type: RT-PCR
Annotation Date: 2017-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5927593
Age: embryonic day 9.5
Specimen Label: Embryo
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5927588
Assay Type: RT-PCR
Annotation Date: 2017-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5927593
Age: postnatal adult
Specimen Label: Placenta
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5927588
Assay Type: RT-PCR
Annotation Date: 2017-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5927601
Age: postnatal adult
Specimen Label: Null
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5927588
Assay Type: RT-PCR
Annotation Date: 2017-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5927601
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7266463
Assay Type: RT-PCR
Annotation Date: 2022-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7266631
Age: embryonic day 16.5
Image: S2
Specimen Label: E16.5 Placenta without decidua
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7266463
Assay Type: RT-PCR
Annotation Date: 2022-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:7266631
Age: embryonic day 16.5
Image: S2
Specimen Label: E16.5 Placenta with decidua
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7266463
Assay Type: RT-PCR
Annotation Date: 2022-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7266631
Age: embryonic day 16.5
Image: S2
Specimen Label: E16.5 Placenta with decidua
Detected: true
Specimen Num: 2
Publication
First Author: Huang ZF
Year: 1997
Journal: Blood
Title: Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice.
Volume: 90
Issue: 3
Pages: 944-51
Publication
First Author: Marjonen H
Year: 2018
Journal: PLoS One
Title: Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model.
Volume: 13
Issue: 5
Pages: e0197461
Publication
First Author: Kulinski TM
Year: 2015
Journal: Dev Biol
Title: Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.
Volume: 402
Issue: 2
Pages: 291-305
Publication
First Author: Ono R
Year: 2006
Journal: Nat Genet
Title: Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.
Volume: 38
Issue: 1
Pages: 101-6
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication  
First Author: Wang ZY
Year: 2021
Journal: Redox Biol
Title: PARP1 deficiency protects against hyperglycemia-induced neointimal hyperplasia by upregulating TFPI2 activity in diabetic mice.
Volume: 46
Pages: 102084
Allele
Name: tissue factor pathway inhibitor 2; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: congenic, mutant strain, targeted mutation