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Search results 1 to 100 out of 4570 for Tg

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Amendola E
Year: 2010
Journal: Endocrinology
Title: A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid.
Volume: 151
Issue: 4
Pages: 1948-58
Publication
First Author: Selmi-Ruby S
Year: 2014
Journal: Endocrinology
Title: The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.
Volume: 155
Issue: 2
Pages: 635-46
Allele
Name: transgene insertion 1, Stefan Offermanns
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Publication
First Author: Fanning TG
Year: 1982
Journal: Nucleic Acids Res
Title: Characterization of a highly repetitive family of DNA sequences in the mouse.
Volume: 10
Issue: 16
Pages: 5003-13
Publication
First Author: Ock S
Year: 2013
Journal: FASEB J
Title: IGF-1 receptor deficiency in thyrocytes impairs thyroid hormone secretion and completely inhibits TSH-stimulated goiter.
Volume: 27
Issue: 12
Pages: 4899-908
Publication
First Author: Calì G
Year: 2007
Journal: Endocrinology
Title: Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation.
Volume: 148
Issue: 6
Pages: 2737-46
Publication
First Author: Ock S
Year: 2018
Journal: Int J Cancer
Title: Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation.
Volume: 143
Issue: 10
Pages: 2458-2469
Publication
First Author: Rodriguez W
Year: 2012
Journal: PLoS One
Title: Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations.
Volume: 7
Issue: 1
Pages: e29929
Genotype
Symbol: Gna11/Gna11 Gnaq/Gnaq Tg(Tg-cre)1Soff/?
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tg-cre)1Soff/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Kero J
Year: 2007
Journal: J Clin Invest
Title: Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development.
Volume: 117
Issue: 9
Pages: 2399-407
Publication
First Author: Undeutsch H
Year: 2014
Journal: Genesis
Title: A mouse model with tamoxifen-inducible thyrocyte-specific cre recombinase activity.
Volume: 52
Issue: 4
Pages: 333-40
Publication  
First Author: Kirschner LS
Year: 2016
Journal: Mol Cell Endocrinol
Title: Mouse models of thyroid cancer: A 2015 update.
Volume: 421
Pages: 18-27
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 1, Samia Selmi-Ruby
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Publication
First Author: Charles RP
Year: 2011
Journal: Cancer Res
Title: Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse.
Volume: 71
Issue: 11
Pages: 3863-71
Publication
First Author: Charles RP
Year: 2014
Journal: Mol Cancer Res
Title: Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis.
Volume: 12
Issue: 7
Pages: 979-86
Allele
Name: transgene insertion, Martin McMahon
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion 1, Jukka Kero
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Genotype
Symbol: Hprt/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Thrb/Thrb Hprt/?
Background: involves: 129/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Thrb/Thrb<+> Hprt/?
Background: involves: 129/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf<+> Tg(Tg-cre/ERT2)#Mmcm/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Tg-cre/ERT2)1Kero/Tg(Tg-cre/ERT2)1Kero
Background: C57BL/6N-Tg(Tg-cre/ERT2)1Kero
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Tg(Tg-cre/ERT2)#Mmcm/?
Background: involves: 129S4/SvJae * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Thrb/Thrb Hprt/Hprt
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Thrb/Thrb<+> Hprt/Hprt
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hprt/Hprt<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Hprt/Hprt
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tg-cre/ERT2)1Kero/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hprt/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hprt/Hprt
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hprt/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Mayerhofer A
Year: 1988
Journal: J Hered
Title: Ultrastructural aspects of the goiter in cog/cog mice.
Volume: 79
Issue: 3
Pages: 200-3
Publication
First Author: Beamer WG
Year: 1987
Journal: Endocrinology
Title: Inherited congenital goiter in mice.
Volume: 120
Issue: 2
Pages: 838-40
Publication
First Author: Adkison LR
Year: 1990
Journal: J Endocrinol
Title: Mutant gene-induced disorders of structure, function and thyroglobulin synthesis in congenital goitre (cog/cog) in mice.
Volume: 126
Issue: 1
Pages: 51-8
Publication
First Author: Kim PS
Year: 2008
Journal: Mol Endocrinol
Title: Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter.
Volume: 22
Issue: 2
Pages: 477-84
Publication
First Author: Wu H
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus.
Volume: 389
Issue: 2
Pages: 269-73
Publication
First Author: Kim PS
Year: 1996
Journal: J Cell Biol
Title: An endoplasmic reticulum storage disease causing congenital goiter with hypothyroidism.
Volume: 133
Issue: 3
Pages: 517-27
Publication
First Author: Lee J
Year: 2009
Journal: J Biol Chem
Title: The cholinesterase-like domain, essential in thyroglobulin trafficking for thyroid hormone synthesis, is required for protein dimerization.
Volume: 284
Issue: 19
Pages: 12752-61
Publication
First Author: Kim PS
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: a model of human endoplasmic reticulum storage diseases.
Volume: 95
Issue: 17
Pages: 9909-13
Publication
First Author: Endo T
Year: 2010
Journal: Mol Endocrinol
Title: Runx2 deficiency in mice causes decreased thyroglobulin expression and hypothyroidism.
Volume: 24
Issue: 6
Pages: 1267-73
Protein Domain
Type: Domain
Description: PT-TG is a conserved region found in many bacterial toxin proteins. It could function as a linker that links N-terminal secretion-related domain and C-terminal toxin domain. It contains a TG motif [].
Publication
First Author: Taylor BA
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: The congenital goiter mutation is linked to the thyroglobulin gene in the mouse.
Volume: 84
Issue: 7
Pages: 1986-90
Publication
First Author: Botta R
Year: 2009
Journal: Endocrinology
Title: Sortilin is a putative postendocytic receptor of thyroglobulin.
Volume: 150
Issue: 1
Pages: 509-18
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Caturegli P
Year: 1997
Journal: Clin Immunol Immunopathol
Title: Cloning and characterization of murine thyroglobulin cDNA.
Volume: 85
Issue: 2
Pages: 221-6
Publication      
First Author: Turer E
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for ito
Publication      
First Author: McAlpine W
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for ito2
Publication      
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for ito4.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for samarai.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Papua.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for sariba.
Publication
First Author: Sugisaki T
Year: 1992
Journal: Neurochem Res
Title: Microcephalic cerebrum with hypomyelination in the congenital goiter mouse (cog).
Volume: 17
Issue: 10
Pages: 1037-40
Publication
First Author: Yoshida S
Year: 1996
Journal: J Clin Endocrinol Metab
Title: A variant of adenomatous goiter with characteristic histology and possible hereditary thyroglobulin abnormality.
Volume: 81
Issue: 5
Pages: 1961-6
Publication
First Author: Kuppers RC
Year: 1996
Journal: Autoimmunity
Title: Mouse thyroglobulin: conservation of sequence homology in C-terminal immunogenic regions of thyroglobulin.
Volume: 23
Issue: 3
Pages: 175-80
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150294
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150294
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150294
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150294
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150293
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150293
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150293
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150293
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150291
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150291
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150291
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150291
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150290
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150290
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150290
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150290
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150286
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6149778
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150286
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150285
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6150299
Assay Type: Western blot
Annotation Date: 2018-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6150285
Age: postnatal
Detected: true
Specimen Num: 1