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Search results 1 to 100 out of 1479 for Tgfbr2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
7048 | TGFBR2
Type: gene
Organism: human
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Gene
100488582 | tgfbr2
Type: gene
Organism: frog, western clawed
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Gene
81810 | Tgfbr2
Type: gene
Organism: rat
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Gene
460243 | TGFBR2
Type: gene
Organism: chimpanzee
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Gene
477039 | TGFBR2
Type: gene
Organism: dog, domestic
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Gene
535376 | TGFBR2
Type: gene
Organism: cattle
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Gene
396399 | TGFBR2
Type: gene
Organism: chicken
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Gene
703088 | TGFBR2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:98729 | Tgfbr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24401272 | J:207994
First Author: Li W
Year: 2014
Journal: J Clin Invest
Title: Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.
Volume: 124
Issue: 2
Pages: 755-67
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Publication
19699732 | J:153638
First Author: Seo HS
Year: 2009
Journal: Dev Biol
Title: Tgfbr2 is required for development of the skull vault.
Volume: 334
Issue: 2
Pages: 481-90
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Publication
38645005 | J:347354
     
First Author: Michaels JR
Year: 2024
Journal: bioRxiv
Title: Genetic Analysis and Functional Assessment of a TGFBR2 Variant in Micrognathia and Cleft Palate.
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Publication
28043895 | J:255163
 
First Author: Peters SB
Year: 2017
Journal: Bone
Title: Tgfbr2 is required in osterix expressing cells for postnatal skeletal development.
Volume: 97
Pages: 54-64
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Publication
24990151 | J:215459
First Author: Hellbach N
Year: 2014
Journal: Hum Mol Genet
Title: Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome.
Volume: 23
Issue: 23
Pages: 6177-90
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Publication
23933490 | J:202347
First Author: Wang Y
Year: 2013
Journal: Dev Biol
Title: Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation.
Volume: 382
Issue: 1
Pages: 27-37
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Publication
22885149 | J:191584
First Author: Sueyoshi T
Year: 2012
Journal: Matrix Biol
Title: Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation.
Volume: 31
Issue: 6
Pages: 352-9
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Publication
22326956 | J:184481
First Author: Iwata J
Year: 2012
Journal: J Clin Invest
Title: Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.
Volume: 122
Issue: 3
Pages: 873-85
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Publication
29228234 | J:318882
First Author: Zhao W
Year: 2018
Journal: J Mol Cell Biol
Title: Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer.
Volume: 10
Issue: 4
Pages: 316-330
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Publication
35688320 | J:344820
First Author: Tosti E
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer.
Volume: 14
Issue: 3
Pages: 693-717
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Publication
12975342 | J:86042
First Author: Ito Y
Year: 2003
Journal: Development
Title: Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects.
Volume: 130
Issue: 21
Pages: 5269-80
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Publication
23975680 | J:203118
First Author: Iwata J
Year: 2014
Journal: Hum Mol Genet
Title: Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice.
Volume: 23
Issue: 1
Pages: 182-93
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Publication
16780827 | J:112634
First Author: Xu X
Year: 2006
Journal: Dev Biol
Title: Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion.
Volume: 297
Issue: 1
Pages: 238-48
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Publication
17822689 | J:128010
First Author: Seo HS
Year: 2007
Journal: Dev Biol
Title: Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints.
Volume: 310
Issue: 2
Pages: 304-16
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Publication
20214815 | J:160241
 
First Author: Sohn P
Year: 2010
Journal: BMC Dev Biol
Title: Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.
Volume: 10
Pages: 29
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Publication
25323858 | J:252827
First Author: Zhao N
Year: 2015
Journal: Circ Res
Title: MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.
Volume: 116
Issue: 1
Pages: 23-34
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Publication
16887142 | J:114624
First Author: Frutkin AD
Year: 2006
Journal: J Mol Cell Cardiol
Title: A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre.
Volume: 41
Issue: 4
Pages: 724-31
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GXD Expression
GXD Expression
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 Wnt1-cre; Tgfbr2 CKO Anterior
Note: Authors state that expression is not decreased in mutant compared with control.
Specimen Label: 3 Wnt1-cre; Tgfbr2 CKO Anterior
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 Wnt1-cre; Tgfbr2 CKO Middle
Note: Authors state that expression is not decreased in mutant compared with control.
Specimen Label: 3 Wnt1-cre; Tgfbr2 CKO Middle
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 Wnt1-cre; Tgfbr2 CKO Posterior
Note: Authors state that expression is not decreased in mutant compared with control.
Specimen Label: 3 Wnt1-cre; Tgfbr2 CKO Posterior
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 K14-cre; Tgfbr2 CKO Anterior
Note: Authors state that expression is dramatically reduced.
Specimen Label: 3 K14-cre; Tgfbr2 CKO Anterior
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 K14-cre; Tgfbr2 CKO Middle
Note: Authors state that expression is dramatically reduced.
Specimen Label: 3 K14-cre; Tgfbr2 CKO Middle
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6467815
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-20
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6467821
Age: embryonic day 15.5
Image: 3 K14-cre; Tgfbr2 CKO Posterior
Note: Authors state that expression is dramatically reduced.
Specimen Label: 3 K14-cre; Tgfbr2 CKO Posterior
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191467
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tgfbr2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191467
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tgfbr2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191467
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tgfbr2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191467
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tgfbr2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191467
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tgfbr2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191467
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tgfbr2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6185063
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191467
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tgfbr2
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7608431
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610022
Age: embryonic day 13.5
Image: 4Db
Note: Staining in an adjacent section indicated some cells co-express Tgfbr2 and Cdkn2a.
Specimen Label: 4Db
Detected: true
Specimen Num: 1
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Protein
Q78JJ8
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: false
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Publication
29282223 | J:261891
First Author: Sakai E
Year: 2018
Journal: Cancer Res
Title: Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Volume: 78
Issue: 5
Pages: 1334-1346
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Publication
11559531 | J:71591
First Author: Im YH
Year: 2001
Journal: Cancer Res
Title: Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
Volume: 61
Issue: 18
Pages: 6665-8
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Publication
10198068 | J:54827
First Author: Joseph H
Year: 1999
Journal: Mol Biol Cell
Title: Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching.
Volume: 10
Issue: 4
Pages: 1221-34
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Publication
33995678 | J:314123
First Author: Zhou Q
Year: 2021
Journal: Theranostics
Title: Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer.
Volume: 11
Issue: 13
Pages: 6592-6606
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Publication
22863752 | J:187587
First Author: Marcoe JP
Year: 2012
Journal: Nat Immunol
Title: TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy.
Volume: 13
Issue: 9
Pages: 843-50
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Publication
9334355 | J:44579
First Author: Serra R
Year: 1997
Journal: J Cell Biol
Title: Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis.
Volume: 139
Issue: 2
Pages: 541-52
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Publication
27378170 | J:254098
 
First Author: Liang Y
Year: 2016
Journal: Sci Rep
Title: Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.
Volume: 6
Pages: 29479
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UniProt Feature
UniProt Feature
Begin: 187
Description: Phosphoserine; by TGFBR2
Type: modified residue
End: 187
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UniProt Feature
UniProt Feature
Begin: 186
Description: Phosphothreonine; by TGFBR2
Type: modified residue
End: 186
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UniProt Feature
UniProt Feature
Begin: 189
Description: Phosphoserine; by TGFBR2
Type: modified residue
End: 189
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UniProt Feature
UniProt Feature
Begin: 191
Description: Phosphoserine; by TGFBR2
Type: modified residue
End: 191
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UniProt Feature
UniProt Feature
Begin: 185
Description: Phosphothreonine; by TGFBR2
Type: modified residue
End: 185
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Publication
8873772 | J:73414
First Author: Oshima M
Year: 1996
Journal: Dev Biol
Title: TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis.
Volume: 179
Issue: 1
Pages: 297-302
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Publication
28957681 | J:253246
First Author: Clements MP
Year: 2017
Journal: Neuron
Title: The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Volume: 96
Issue: 1
Pages: 98-114.e7
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Publication
18167337 | J:131064
First Author: Yang L
Year: 2008
Journal: Cancer Cell
Title: Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.
Volume: 13
Issue: 1
Pages: 23-35
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Publication
29352019 | J:260469
First Author: Lu X
Year: 2017
Journal: Genes Dev
Title: Opposing roles of TGFβ and BMP signaling in prostate cancer development.
Volume: 31
Issue: 23-24
Pages: 2337-2342
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Publication
28219480 | J:241653
   
First Author: McCauley HA
Year: 2017
Journal: Elife
Title: De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones.
Volume: 6
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Publication
21420963 | J:171227
First Author: Jin H
Year: 2011
Journal: FEBS Lett
Title: TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue.
Volume: 585
Issue: 8
Pages: 1209-15
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Publication
30275444 | J:267600
First Author: Zöller T
Year: 2018
Journal: Nat Commun
Title: Silencing of TGFβ signalling in microglia results in impaired homeostasis.
Volume: 9
Issue: 1
Pages: 4011
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Publication
25779936 | J:222978
First Author: Luo Y
Year: 2015
Journal: J Pathol
Title: A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells.
Volume: 236
Issue: 3
Pages: 384-94
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Publication
17050629 | J:137594
First Author: Jiao K
Year: 2006
Journal: Development
Title: Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development.
Volume: 133
Issue: 22
Pages: 4585-93
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Publication
20652948 | J:163274
First Author: Robson A
Year: 2010
Journal: Dev Dyn
Title: The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development.
Volume: 239
Issue: 9
Pages: 2435-42
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Publication
17727833 | J:128003
First Author: Hosokawa R
Year: 2007
Journal: Dev Biol
Title: TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development.
Volume: 310
Issue: 1
Pages: 140-53
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GXD Expression
GXD Expression
     
Probe: MGI:7623831
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:7624031
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623860
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:7624035
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623873
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:7624037
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623829
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:7624038
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623859
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624040
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623855
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624041
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623834
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624044
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623854
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624045
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623856
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624050
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623828
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624047
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623836
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624103
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623832
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624049
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7623857
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624046
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623861
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624042
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623862
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624051
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623835
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624052
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623858
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624100
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623833
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624048
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7623874
Assay Type: RT-PCR
Annotation Date: 2024-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7624043
Age: embryonic day 13.5
Specimen Label: Tgfbr2 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
23661553 | J:203558
First Author: Pang Y
Year: 2013
Journal: Cancer Discov
Title: TGF-β signaling in myeloid cells is required for tumor metastasis.
Volume: 3
Issue: 8
Pages: 936-51
•
•
•
•
•
Publication
23378339 | J:196975
First Author: Miyabayashi K
Year: 2013
Journal: Cancer Res
Title: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals.
Volume: 73
Issue: 7
Pages: 2221-34
•
•
•
•
•
Publication
15781643 | J:97162
First Author: Forrester E
Year: 2005
Journal: Cancer Res
Title: Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
Volume: 65
Issue: 6
Pages: 2296-302
•
•
•
•
•
Publication
26494233 | J:242387
First Author: Hu JH
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice.
Volume: 35
Issue: 12
Pages: 2647-56
•
•
•
•
•
Publication
15389868 | J:105591
First Author: Oe S
Year: 2004
Journal: Hepatology
Title: Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice.
Volume: 40
Issue: 5
Pages: 1098-105
•
•
•
•
•
Publication
27790711 | J:238081
First Author: Morris SM
Year: 2017
Journal: Int J Cancer
Title: Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.
Volume: 140
Issue: 4
Pages: 853-863
•
•
•
•
•
Publication
33881909 | J:304787
     
First Author: Miao Q
Year: 2021
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice.
•
•
•
•
•
Publication
15256431 | J:91510
First Author: Biswas S
Year: 2004
Journal: Cancer Res
Title: Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer.
Volume: 64
Issue: 14
Pages: 4687-92
•
•
•
•
•
Publication
35269767 | J:333695
 
First Author: Bielmeier CB
Year: 2022
Journal: Int J Mol Sci
Title: Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways.
Volume: 23
Issue: 5
•
•
•
•
•
Publication
16824508 | J:119316
First Author: Baffi MO
Year: 2006
Journal: Dev Biol
Title: Tgfbr2 regulates the maintenance of boundaries in the axial skeleton.
Volume: 296
Issue: 2
Pages: 363-74
•
•
•
•
•
Publication
27156386 | J:254601
First Author: Cortez VS
Year: 2016
Journal: Immunity
Title: Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands.
Volume: 44
Issue: 5
Pages: 1127-39
•
•
•
•
•
Publication
17449229 | J:121723
First Author: Oka S
Year: 2007
Journal: Mech Dev
Title: Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation.
Volume: 124
Issue: 6
Pages: 409-15
•
•
•
•
•
Publication
31961320 | J:305431
   
First Author: Tan GK
Year: 2020
Journal: Elife
Title: Tgfβ signaling is critical for maintenance of the tendon cell fate.
Volume: 9
•
•
•
•
•
Publication
30555301 | J:350020
 
First Author: Weise SC
Year: 2018
Journal: Front Cell Neurosci
Title: TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain.
Volume: 12
Pages: 448
•
•
•
•
•
Publication
29051340 | J:271782
First Author: Hollander MC
Year: 2017
Journal: Circ Res
Title: Attenuation of Myeloid-Specific TGFβ Signaling Induces Inflammatory Cerebrovascular Disease and Stroke.
Volume: 121
Issue: 12
Pages: 1360-1369
•
•
•
•
•
Publication
22685318 | J:188061
First Author: Novitskiy SV
Year: 2012
Journal: J Leukoc Biol
Title: Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.
Volume: 92
Issue: 3
Pages: 641-51
•
•
•
•
•
Publication
23695722 | J:200523
First Author: Li J
Year: 2013
Journal: Carcinogenesis
Title: Myeloid TGF-β signaling contributes to colitis-associated tumorigenesis in mice.
Volume: 34
Issue: 9
Pages: 2099-108
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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