Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Li W |
Year: |
2014 |
Journal: |
J Clin Invest |
Title: |
Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis. |
Volume: |
124 |
Issue: |
2 |
Pages: |
755-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seo HS |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
Tgfbr2 is required for development of the skull vault. |
Volume: |
334 |
Issue: |
2 |
Pages: |
481-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peters SB |
Year: |
2017 |
Journal: |
Bone |
Title: |
Tgfbr2 is required in osterix expressing cells for postnatal skeletal development. |
Volume: |
97 |
|
Pages: |
54-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hellbach N |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. |
Volume: |
23 |
Issue: |
23 |
Pages: |
6177-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation. |
Volume: |
382 |
Issue: |
1 |
Pages: |
27-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sueyoshi T |
Year: |
2012 |
Journal: |
Matrix Biol |
Title: |
Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. |
Volume: |
31 |
Issue: |
6 |
Pages: |
352-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwata J |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. |
Volume: |
122 |
Issue: |
3 |
Pages: |
873-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tosti E |
Year: |
2022 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer. |
Volume: |
14 |
Issue: |
3 |
Pages: |
693-717 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao W |
Year: |
2018 |
Journal: |
J Mol Cell Biol |
Title: |
Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer. |
Volume: |
10 |
Issue: |
4 |
Pages: |
316-330 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito Y |
Year: |
2003 |
Journal: |
Development |
Title: |
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. |
Volume: |
130 |
Issue: |
21 |
Pages: |
5269-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwata J |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice. |
Volume: |
23 |
Issue: |
1 |
Pages: |
182-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu X |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion. |
Volume: |
297 |
Issue: |
1 |
Pages: |
238-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seo HS |
Year: |
2007 |
Journal: |
Dev Biol |
Title: |
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints. |
Volume: |
310 |
Issue: |
2 |
Pages: |
304-16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 Wnt1-cre; Tgfbr2 CKO Anterior |
Note: |
Authors state that expression is not decreased in mutant compared with control. |
Specimen Label: |
3 Wnt1-cre; Tgfbr2 CKO Anterior |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 Wnt1-cre; Tgfbr2 CKO Middle |
Note: |
Authors state that expression is not decreased in mutant compared with control. |
Specimen Label: |
3 Wnt1-cre; Tgfbr2 CKO Middle |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 Wnt1-cre; Tgfbr2 CKO Posterior |
Note: |
Authors state that expression is not decreased in mutant compared with control. |
Specimen Label: |
3 Wnt1-cre; Tgfbr2 CKO Posterior |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 K14-cre; Tgfbr2 CKO Anterior |
Note: |
Authors state that expression is dramatically reduced. |
Specimen Label: |
3 K14-cre; Tgfbr2 CKO Anterior |
|
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 K14-cre; Tgfbr2 CKO Middle |
Note: |
Authors state that expression is dramatically reduced. |
Specimen Label: |
3 K14-cre; Tgfbr2 CKO Middle |
|
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6467815 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-20 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6467821 |
Age: |
embryonic day 15.5 |
Image: |
3 K14-cre; Tgfbr2 CKO Posterior |
Note: |
Authors state that expression is dramatically reduced. |
Specimen Label: |
3 K14-cre; Tgfbr2 CKO Posterior |
|
Specimen Num: |
9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sohn P |
Year: |
2010 |
Journal: |
BMC Dev Biol |
Title: |
Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc. |
Volume: |
10 |
|
Pages: |
29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao N |
Year: |
2015 |
Journal: |
Circ Res |
Title: |
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells. |
Volume: |
116 |
Issue: |
1 |
Pages: |
23-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frutkin AD |
Year: |
2006 |
Journal: |
J Mol Cell Cardiol |
Title: |
A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre. |
Volume: |
41 |
Issue: |
4 |
Pages: |
724-31 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6191467 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Tgfbr2 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6191467 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Tgfbr2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191467 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Tgfbr2 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191467 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Tgfbr2 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191467 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Tgfbr2 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191467 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Tgfbr2 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185063 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191467 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Tgfbr2 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7608431 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-03-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783721 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7610022 |
Age: |
embryonic day 13.5 |
Image: |
4Db |
Note: |
Staining in an adjacent section indicated some cells co-express Tgfbr2 and Cdkn2a. |
Specimen Label: |
4Db |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
132
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakai E |
Year: |
2018 |
Journal: |
Cancer Res |
Title: |
Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer. |
Volume: |
78 |
Issue: |
5 |
Pages: |
1334-1346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Im YH |
Year: |
2001 |
Journal: |
Cancer Res |
Title: |
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis. |
Volume: |
61 |
Issue: |
18 |
Pages: |
6665-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joseph H |
Year: |
1999 |
Journal: |
Mol Biol Cell |
Title: |
Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching. |
Volume: |
10 |
Issue: |
4 |
Pages: |
1221-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Q |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer. |
Volume: |
11 |
Issue: |
13 |
Pages: |
6592-6606 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marcoe JP |
Year: |
2012 |
Journal: |
Nat Immunol |
Title: |
TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy. |
Volume: |
13 |
Issue: |
9 |
Pages: |
843-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serra R |
Year: |
1997 |
Journal: |
J Cell Biol |
Title: |
Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. |
Volume: |
139 |
Issue: |
2 |
Pages: |
541-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang Y |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model. |
Volume: |
6 |
|
Pages: |
29479 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang L |
Year: |
2008 |
Journal: |
Cancer Cell |
Title: |
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. |
Volume: |
13 |
Issue: |
1 |
Pages: |
23-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oshima M |
Year: |
1996 |
Journal: |
Dev Biol |
Title: |
TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. |
Volume: |
179 |
Issue: |
1 |
Pages: |
297-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clements MP |
Year: |
2017 |
Journal: |
Neuron |
Title: |
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration. |
Volume: |
96 |
Issue: |
1 |
Pages: |
98-114.e7 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
187 |
Description: |
Phosphoserine; by TGFBR2 |
Type: |
modified residue |
End: |
187 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
186 |
Description: |
Phosphothreonine; by TGFBR2 |
Type: |
modified residue |
End: |
186 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
189 |
Description: |
Phosphoserine; by TGFBR2 |
Type: |
modified residue |
End: |
189 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
191 |
Description: |
Phosphoserine; by TGFBR2 |
Type: |
modified residue |
End: |
191 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
185 |
Description: |
Phosphothreonine; by TGFBR2 |
Type: |
modified residue |
End: |
185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu X |
Year: |
2017 |
Journal: |
Genes Dev |
Title: |
Opposing roles of TGFβ and BMP signaling in prostate cancer development. |
Volume: |
31 |
Issue: |
23-24 |
Pages: |
2337-2342 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin H |
Year: |
2011 |
Journal: |
FEBS Lett |
Title: |
TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue. |
Volume: |
585 |
Issue: |
8 |
Pages: |
1209-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zöller T |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Silencing of TGFβ signalling in microglia results in impaired homeostasis. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4011 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCauley HA |
Year: |
2017 |
Journal: |
Elife |
Title: |
De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2015 |
Journal: |
J Pathol |
Title: |
A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. |
Volume: |
236 |
Issue: |
3 |
Pages: |
384-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiao K |
Year: |
2006 |
Journal: |
Development |
Title: |
Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development. |
Volume: |
133 |
Issue: |
22 |
Pages: |
4585-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosokawa R |
Year: |
2007 |
Journal: |
Dev Biol |
Title: |
TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development. |
Volume: |
310 |
Issue: |
1 |
Pages: |
140-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robson A |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development. |
Volume: |
239 |
Issue: |
9 |
Pages: |
2435-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baffi MO |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Tgfbr2 regulates the maintenance of boundaries in the axial skeleton. |
Volume: |
296 |
Issue: |
2 |
Pages: |
363-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyabayashi K |
Year: |
2013 |
Journal: |
Cancer Res |
Title: |
Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. |
Volume: |
73 |
Issue: |
7 |
Pages: |
2221-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pang Y |
Year: |
2013 |
Journal: |
Cancer Discov |
Title: |
TGF-β signaling in myeloid cells is required for tumor metastasis. |
Volume: |
3 |
Issue: |
8 |
Pages: |
936-51 |
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Publication |
First Author: |
Bielmeier CB |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways. |
Volume: |
23 |
Issue: |
5 |
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Publication |
First Author: |
Forrester E |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. |
Volume: |
65 |
Issue: |
6 |
Pages: |
2296-302 |
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Publication |
First Author: |
Oe S |
Year: |
2004 |
Journal: |
Hepatology |
Title: |
Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice. |
Volume: |
40 |
Issue: |
5 |
Pages: |
1098-105 |
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Publication |
First Author: |
Miao Q |
Year: |
2021 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice. |
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Publication |
First Author: |
Biswas S |
Year: |
2004 |
Journal: |
Cancer Res |
Title: |
Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer. |
Volume: |
64 |
Issue: |
14 |
Pages: |
4687-92 |
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Publication |
First Author: |
Hu JH |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice. |
Volume: |
35 |
Issue: |
12 |
Pages: |
2647-56 |
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Publication |
First Author: |
Oshima H |
Year: |
2015 |
Journal: |
Cancer Res |
Title: |
Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer. |
Volume: |
75 |
Issue: |
4 |
Pages: |
766-76 |
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Publication |
First Author: |
Cortez VS |
Year: |
2016 |
Journal: |
Immunity |
Title: |
Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands. |
Volume: |
44 |
Issue: |
5 |
Pages: |
1127-39 |
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Publication |
First Author: |
Oka S |
Year: |
2007 |
Journal: |
Mech Dev |
Title: |
Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation. |
Volume: |
124 |
Issue: |
6 |
Pages: |
409-15 |
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Publication |
First Author: |
Tan GK |
Year: |
2020 |
Journal: |
Elife |
Title: |
Tgfβ signaling is critical for maintenance of the tendon cell fate. |
Volume: |
9 |
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Publication |
First Author: |
Li J |
Year: |
2013 |
Journal: |
Carcinogenesis |
Title: |
Myeloid TGF-β signaling contributes to colitis-associated tumorigenesis in mice. |
Volume: |
34 |
Issue: |
9 |
Pages: |
2099-108 |
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Publication |
First Author: |
Xu R |
Year: |
2020 |
Journal: |
Biomed Pharmacother |
Title: |
Radix Rehmanniae Praeparata promotes bone fracture healing through activation of TGF-β signaling in mesenchymal progenitors. |
Volume: |
130 |
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Pages: |
110581 |
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Publication |
First Author: |
Novitskiy SV |
Year: |
2012 |
Journal: |
J Leukoc Biol |
Title: |
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties. |
Volume: |
92 |
Issue: |
3 |
Pages: |
641-51 |
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Publication |
First Author: |
Xia C |
Year: |
2020 |
Journal: |
Cell Prolif |
Title: |
TGF-β/Smad2 signalling regulates enchondral bone formation of Gli1+ periosteal cells during fracture healing. |
Volume: |
53 |
Issue: |
11 |
Pages: |
e12904 |
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Publication |
First Author: |
Hollander MC |
Year: |
2017 |
Journal: |
Circ Res |
Title: |
Attenuation of Myeloid-Specific TGFβ Signaling Induces Inflammatory Cerebrovascular Disease and Stroke. |
Volume: |
121 |
Issue: |
12 |
Pages: |
1360-1369 |
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Publication |
First Author: |
Anthwal N |
Year: |
2008 |
Journal: |
Dev Dyn |
Title: |
The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary. |
Volume: |
237 |
Issue: |
6 |
Pages: |
1604-13 |
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Publication |
First Author: |
Romero-Gallo J |
Year: |
2005 |
Journal: |
Oncogene |
Title: |
Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy. |
Volume: |
24 |
Issue: |
18 |
Pages: |
3028-41 |
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Publication |
First Author: |
Meng Q |
Year: |
2018 |
Journal: |
Circ Res |
Title: |
Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. |
Volume: |
123 |
Issue: |
12 |
Pages: |
1285-1297 |
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Publication |
First Author: |
Wang PE |
Year: |
2018 |
Journal: |
J Transl Med |
Title: |
Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling. |
Volume: |
16 |
Issue: |
1 |
Pages: |
72 |
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Publication |
First Author: |
Tsujino K |
Year: |
2017 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma. |
Volume: |
312 |
Issue: |
1 |
Pages: |
L22-L31 |
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Publication |
First Author: |
Andl T |
Year: |
2014 |
Journal: |
Carcinogenesis |
Title: |
Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. |
Volume: |
35 |
Issue: |
11 |
Pages: |
2602-10 |
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Publication |
First Author: |
Ho TV |
Year: |
2015 |
Journal: |
Dev Biol |
Title: |
Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development. |
Volume: |
400 |
Issue: |
2 |
Pages: |
180-90 |
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Publication |
First Author: |
Yang P |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events. |
Volume: |
6 |
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Pages: |
35444 |
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Publication |
First Author: |
Ni N |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract. |
Volume: |
11 |
Issue: |
1 |
Pages: |
9294 |
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Publication |
First Author: |
Shen J |
Year: |
2013 |
Journal: |
Arthritis Rheum |
Title: |
Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in mice. |
Volume: |
65 |
Issue: |
12 |
Pages: |
3107-19 |
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Publication |
First Author: |
Ramalingam R |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity. |
Volume: |
189 |
Issue: |
8 |
Pages: |
3878-93 |
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Publication |
First Author: |
McCauley HA |
Year: |
2014 |
Journal: |
Development |
Title: |
TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. |
Volume: |
141 |
Issue: |
23 |
Pages: |
4628-39 |
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Publication |
First Author: |
Muñoz NM |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. |
Volume: |
66 |
Issue: |
20 |
Pages: |
9837-44 |
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Publication |
First Author: |
Li X |
Year: |
2012 |
Journal: |
Mol Cancer Res |
Title: |
Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions. |
Volume: |
10 |
Issue: |
4 |
Pages: |
494-503 |
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Publication |
First Author: |
Borczuk AC |
Year: |
2011 |
Journal: |
Cancer Res |
Title: |
Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor. |
Volume: |
71 |
Issue: |
21 |
Pages: |
6665-75 |
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Publication |
First Author: |
Meng X |
Year: |
2018 |
Journal: |
Cancer Lett |
Title: |
Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis. |
Volume: |
418 |
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Pages: |
109-118 |
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Publication |
First Author: |
Gao F |
Year: |
2014 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm. |
Volume: |
454 |
Issue: |
1 |
Pages: |
137-43 |
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Publication |
First Author: |
Gao F |
Year: |
2014 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling. |
Volume: |
454 |
Issue: |
1 |
Pages: |
245-50 |
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Publication |
First Author: |
Liu Y |
Year: |
2014 |
Journal: |
Eur J Immunol |
Title: |
AKT hyperactivation confers a Th1 phenotype in thymic Treg cells deficient in TGF-β receptor II signaling. |
Volume: |
44 |
Issue: |
2 |
Pages: |
521-32 |
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