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Search results 1 to 94 out of 94 for Thoc1

0.046s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Wang X
Year: 2007
Journal: Genesis
Title: An allelic series for studying the mouse Thoc1 gene.
Volume: 45
Issue: 1
Pages: 32-7
Publication  
First Author: Chinnam M
Year: 2014
Journal: J Natl Cancer Inst
Title: The Thoc1 ribonucleoprotein and prostate cancer progression.
Volume: 106
Issue: 11
Publication
First Author: Wang X
Year: 2009
Journal: Mol Cell Biol
Title: Thoc1 deficiency compromises gene expression necessary for normal testis development in the mouse.
Volume: 29
Issue: 10
Pages: 2794-803
Publication
First Author: Pitzonka L
Year: 2014
Journal: PLoS One
Title: The Thoc1 encoded ribonucleoprotein is required for myeloid progenitor cell homeostasis in the adult mouse.
Volume: 9
Issue: 5
Pages: e97628
Publication
First Author: Chinnam M
Year: 2016
Journal: Mol Cell Biol
Title: Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice.
Volume: 36
Issue: 11
Pages: 1621-7
Publication
First Author: Wang X
Year: 2006
Journal: Mol Cell Biol
Title: Thoc1/Hpr1/p84 is essential for early embryonic development in the mouse.
Volume: 26
Issue: 11
Pages: 4362-7
Publication
First Author: Pitzonka L
Year: 2013
Journal: Mol Cell Biol
Title: The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine.
Volume: 33
Issue: 17
Pages: 3505-14
Publication  
First Author: Mancini A
Year: 2010
Journal: BMC Biol
Title: THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo.
Volume: 8
Pages: 1
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Domínguez-Sánchez MS
Year: 2011
Journal: PLoS Genet
Title: Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
Volume: 7
Issue: 12
Pages: e1002386
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3664086
Age: embryonic day 1.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3664086
Age: embryonic day 2.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3664086
Age: embryonic day 2.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3664086
Age: embryonic day 3.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3664086
Age: embryonic day 0.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3664030
Assay Type: RT-PCR
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3664086
Age: embryonic day 3.5
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3664083
Assay Type: Immunohistochemistry
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3664087
Age: embryonic day 12.5
Note: Nuclear expression was observed in all tissues and cell types detected in the sagittal section of the embryo.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1508333
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4828700
Age: embryonic day 14.5
Image: euxassay_006725_16
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3664083
Assay Type: Immunohistochemistry
Annotation Date: 2006-10-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:3664087
Age: embryonic day 3.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3664083
Assay Type: Immunohistochemistry
Annotation Date: 2006-10-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:3664087
Age: embryonic day 3.5
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3664083
Assay Type: Immunohistochemistry
Annotation Date: 2006-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:3664087
Age: embryonic day 2.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3664083
Assay Type: Immunohistochemistry
Annotation Date: 2006-10-20
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:3664087
Age: embryonic day 2.5
Detected: true
Specimen Num: 3
Publication
First Author: Wang L
Year: 2013
Journal: Cell Stem Cell
Title: The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming.
Volume: 13
Issue: 6
Pages: 676-90
Publication  
First Author: Kafer GR
Year: 2020
Journal: Front Cell Dev Biol
Title: A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis.
Volume: 8
Pages: 416
Publication
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Protein
Organism: Mus musculus
Length: 397  
Fragment?: true
Protein Domain
Type: Family
Description: The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm.
Protein
Organism: Mus musculus
Length: 657  
Fragment?: false
Protein
Organism: Mus musculus
Length: 385  
Fragment?: true
Publication
First Author: Merz C
Year: 2007
Journal: RNA
Title: Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment.
Volume: 13
Issue: 1
Pages: 116-28
Protein Domain
Type: Domain
Description: The THO/TREX complex is the transcription- and export-related complex associated with spliceosomes that preferentially deal with spliced mRNAs as opposed to unspliced mRNAs. Thoc2 plays a role in RNA polymerase II (RNA pol II)-dependent transcription and is required for the stability of DNA repeats []. In humans, the TRE complex is comprised of the exon-junction-associated proteins Aly/REF and UAP56 together with the THO proteins THOC1 (hHpr1/p84), Thoc2 (hRlr1), THOC3 (hTex1), THOC5 (fSAP79), THOC6 (fSAP35), and THOC7 (fSAP24). Although much evidence indicates that the function of the TREX complex as an adaptor between the mRNA and components of the export machinery is conserved among eukaryotes, in Drosophila the majority of mRNAs can be exported from the nucleus independently of the THO complex []. This entry represents a conserved domain found towards the N terminus of these proteins.
Publication
First Author: Yu T
Year: 2021
Journal: Nat Commun
Title: Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes.
Volume: 12
Issue: 1
Pages: 73
Protein
Organism: Mus musculus
Length: 1594  
Fragment?: false
Protein
Organism: Mus musculus
Length: 921  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1589  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1017  
Fragment?: true
Publication
First Author: Piruat JI
Year: 1998
Journal: EMBO J
Title: A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.
Volume: 17
Issue: 16
Pages: 4859-72