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Search results 1 to 100 out of 2301 for Thy1

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Thy-1 membrane glycoprotein (also known as CD90) was identified as an activation-associated cell adhesion molecule on human dermal microvascular endothelial cells. Its cellular effects vary; however, it most often seems to affect cell-cell or cell-matrix interactions and cellular adhesion and migration [, ]. Thy-1 interacts with the leukocyte integrin Mac-1 and may play an important role in the regulation of leukocyte recruitment to sites of inflammation []. It also plays an important role in normal retinal development [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: McCullough KM
Year: 2016
Journal: Nat Commun
Title: Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala.
Volume: 7
Pages: 13149
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Simon PD
Year: 1999
Journal: Brain Res Dev Brain Res
Title: Thy-1 is critical for normal retinal development.
Volume: 117
Issue: 2
Pages: 219-23
Publication
First Author: Kaukua N
Year: 2014
Journal: Nature
Title: Glial origin of mesenchymal stem cells in a tooth model system.
Volume: 513
Issue: 7519
Pages: 551-4
Publication
First Author: Paine A
Year: 2018
Journal: FASEB J
Title: Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.
Volume: 32
Issue: 6
Pages: 3174-3183
Publication
First Author: Woeller CF
Year: 2015
Journal: FASEB J
Title: Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.
Volume: 29
Issue: 3
Pages: 920-31
Publication
First Author: Cohen PY
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Thy1 up-regulates FasL expression in lung myofibroblasts via Src family kinases.
Volume: 40
Issue: 2
Pages: 231-8
Protein
Organism: Mus musculus
Length: 162  
Fragment?: false
Protein
Organism: Mus musculus
Length: 162  
Fragment?: false
Protein
Organism: Mus musculus
Length: 125  
Fragment?: true
Publication
First Author: Wetzel A
Year: 2004
Journal: J Immunol
Title: Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18).
Volume: 172
Issue: 6
Pages: 3850-9
Publication  
First Author: Leyton L
Year: 2014
Journal: Adv Neurobiol
Title: Thy-1 modulates neurological cell-cell and cell-matrix interactions through multiple molecular interactions.
Volume: 8
Pages: 3-20
Publication
First Author: Barker TH
Year: 2004
Journal: Exp Cell Res
Title: Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity.
Volume: 295
Issue: 2
Pages: 488-96
Publication
First Author: Itami S
Year: 2011
Journal: Biol Reprod
Title: The roles of THY1 and integrin beta3 in cell adhesion during theca cell layer formation and the effect of follicle-stimulating hormone on THY1 and integrin beta3 localization in mouse ovarian follicles.
Volume: 84
Issue: 5
Pages: 986-95
Allele
Name: transgene insertion 1, Fred Van Leuven
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Publication
First Author: Heimer-McGinn V
Year: 2011
Journal: Genesis
Title: Efficient inducible Pan-neuronal cre-mediated recombination in SLICK-H transgenic mice.
Volume: 49
Issue: 12
Pages: 942-9
Publication
First Author: Price V
Year: 2013
Journal: J Neurosci Res
Title: Conditional deletion of histone deacetylase-4 in the central nervous system has no major effect on brain architecture or neuronal viability.
Volume: 91
Issue: 3
Pages: 407-15
Strain
Attribute String: targeted mutation, congenic, mutant strain, transgenic
Strain
Attribute String: mutant strain, transgenic, coisogenic
Genotype
Symbol: Ifngr1/Ifngr1 Tg(Thy1-cre)1Vln/?
Background: B6.Cg-Ifngr1 Tg(Thy1-cre)1Vln
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Cho KI
Year: 2017
Journal: Dis Model Mech
Title: Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.
Volume: 10
Issue: 5
Pages: 559-579
Publication
First Author: Dewachter I
Year: 2008
Journal: Neurobiol Aging
Title: Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
Volume: 29
Issue: 5
Pages: 639-52
Allele
Name: transgene insertion H, Guoping Feng
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Reporter
Publication categories: ProxyCollection
Publication
First Author: Jung CK
Year: 2011
Journal: J Neurochem
Title: Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
Volume: 119
Issue: 5
Pages: 1064-73
Publication
First Author: Herms J
Year: 2003
Journal: J Biol Chem
Title: Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
Volume: 278
Issue: 4
Pages: 2484-9
Publication  
First Author: Kondratiuk I
Year: 2013
Journal: Behav Brain Res
Title: Glycogen synthase kinase-3beta affects size of dentate gyrus and species-typical behavioral tasks in transgenic and knockout mice.
Volume: 248
Pages: 46-50
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-APPLon)2Vln/? Tg(Thy1-cre)1Vln/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: English AW
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Small-molecule trkB agonists promote axon regeneration in cut peripheral nerves.
Volume: 110
Issue: 40
Pages: 16217-22
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Rada P
Year: 2012
Journal: Mol Cell Biol
Title: Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis.
Volume: 32
Issue: 17
Pages: 3486-99
Publication
First Author: Stefanoska K
Year: 2018
Journal: Sci Rep
Title: Neuronal MAP kinase p38α inhibits c-Jun N-terminal kinase to modulate anxiety-related behaviour.
Volume: 8
Issue: 1
Pages: 14296
Allele
Name: transgene insertion 1, Gunther Schutz
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Ris L
Year: 2003
Journal: J Biol Chem
Title: Capacitative calcium entry induces hippocampal long term potentiation in the absence of presenilin-1.
Volume: 278
Issue: 45
Pages: 44393-9
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-cre)1Vln/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dscam/Dscam Tg(Thy1-cre)1Vln/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Panx1/Panx1 Tg(Thy1-cre)1Vln/?
Background: B6.Cg-Panx1 Tg(Thy1-cre)1Vln
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dctn1/Dctn1 Tg(Thy1-cre)1Vln/?
Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-cre)1Vln/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Jardí F
Year: 2017
Journal: Mol Cell Endocrinol
Title: A shortened tamoxifen induction scheme to induce CreER recombinase without side effects on the male mouse skeleton.
Volume: 452
Pages: 57-63
Publication
First Author: Jardí F
Year: 2019
Journal: J Bone Miner Res
Title: Androgen Receptor in Neurons Slows Age-Related Cortical Thinning in Male Mice.
Volume: 34
Issue: 3
Pages: 508-519
Publication
First Author: Feng L
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension.
Volume: 57
Issue: 8
Pages: 3793-802
Publication
First Author: Bhaskaran S
Year: 2020
Journal: Aging Cell
Title: Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice.
Volume: 19
Issue: 10
Pages: e13225
Publication
First Author: Dewachter I
Year: 2002
Journal: J Neurosci
Title: Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Volume: 22
Issue: 9
Pages: 3445-53
Publication
First Author: Perez EJ
Year: 2017
Journal: J Clin Invest
Title: Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.
Volume: 127
Issue: 8
Pages: 3114-3125
Publication
First Author: Kim NR
Year: 2020
Journal: FASEB J
Title: Estrogen receptor alpha signaling in extrahypothalamic neurons during late puberty decreases bone size and strength in female but not in male mice.
Volume: 34
Issue: 5
Pages: 7118-7126
Strain
Attribute String: mutant stock, transgenic
Publication  
First Author: Maurin H
Year: 2013
Journal: Mol Brain
Title: Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase.
Volume: 6
Pages: 27
Genotype
Symbol: Tg(CAG-cat,-lacZ)1Brn/? Tg(Thy1-cre)1Vln/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Duan X
Year: 2015
Journal: Neuron
Title: Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling.
Volume: 85
Issue: 6
Pages: 1244-56
Publication
First Author: Kreutzfeldt M
Year: 2013
Journal: J Exp Med
Title: Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.
Volume: 210
Issue: 10
Pages: 2087-103
Publication
First Author: Dvoriantchikova G
Year: 2012
Journal: PLoS One
Title: Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury.
Volume: 7
Issue: 2
Pages: e31991
Publication
First Author: Vajda F
Year: 2015
Journal: Cell Death Differ
Title: Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve.
Volume: 22
Issue: 2
Pages: 323-35
Publication
First Author: Zemmar A
Year: 2018
Journal: Cereb Cortex
Title: Oligodendrocyte- and Neuron-Specific Nogo-A Restrict Dendritic Branching and Spine Density in the Adult Mouse Motor Cortex.
Volume: 28
Issue: 6
Pages: 2109-2117
Publication
First Author: McAvoy KM
Year: 2019
Journal: PLoS One
Title: Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo.
Volume: 14
Issue: 8
Pages: e0220125
Publication
First Author: Moore DL
Year: 2009
Journal: Science
Title: KLF family members regulate intrinsic axon regeneration ability.
Volume: 326
Issue: 5950
Pages: 298-301
Genotype
Symbol: Tg(Thy1-cre/PGR)1Gsc/? Tg(CAG-lacZ)32And/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Akbik FV
Year: 2013
Journal: Neuron
Title: Anatomical plasticity of adult brain is titrated by Nogo Receptor 1.
Volume: 77
Issue: 5
Pages: 859-66
Publication  
First Author: Liz MA
Year: 2014
Journal: BMC Biol
Title: Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.
Volume: 12
Pages: 47
Publication
First Author: Saifetiarova J
Year: 2017
Journal: J Neurosci
Title: Early and Late Loss of the Cytoskeletal Scaffolding Protein, Ankyrin G Reveals Its Role in Maturation and Maintenance of Nodes of Ranvier in Myelinated Axons.
Volume: 37
Issue: 10
Pages: 2524-2538
Publication  
First Author: Taylor AM
Year: 2018
Journal: eNeuro
Title: Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan.
Volume: 5
Issue: 3
Publication
First Author: Ittner A
Year: 2016
Journal: Science
Title: Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.
Volume: 354
Issue: 6314
Pages: 904-908
Publication  
First Author: Heimer-McGinn V
Year: 2013
Journal: Neurosci Lett
Title: Decreased dendritic spine density as a consequence of tetanus toxin light chain expression in single neurons in vivo.
Volume: 555
Pages: 36-41
Publication
First Author: Young P
Year: 2008
Journal: Nat Neurosci
Title: Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice.
Volume: 11
Issue: 6
Pages: 721-8
Publication  
First Author: Stone S
Year: 2019
Journal: JCI Insight
Title: Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis.
Volume: 4
Issue: 2
Publication  
First Author: Scott J
Year: 2019
Journal: iScience
Title: Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function.
Volume: 20
Pages: 25-41
Publication
First Author: Hass DT
Year: 2019
Journal: J Neurosci
Title: Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma.
Volume: 39
Issue: 18
Pages: 3582-3596
Publication  
First Author: Harun-Or-Rashid M
Year: 2020
Journal: Neurobiol Dis
Title: MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.
Volume: 141
Pages: 104944
Publication
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
Publication
First Author: Liu Q
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: PGE2 signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia.
Volume: 116
Issue: 20
Pages: 10019-10024
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Thy1-cre)1Vln/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Hardt S
Year: 2017
Journal: Biochim Biophys Acta
Title: Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain.
Volume: 1863
Issue: 11
Pages: 2727-2745
Publication
First Author: Ramadori G
Year: 2019
Journal: Nat Commun
Title: S100A9 extends lifespan in insulin deficiency.
Volume: 10
Issue: 1
Pages: 3545
Publication
First Author: Wilhelm JC
Year: 2012
Journal: J Neurosci
Title: Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration.
Volume: 32
Issue: 14
Pages: 5002-9
Publication  
First Author: Taylor AM
Year: 2017
Journal: Front Cell Neurosci
Title: Postnatal Loss of Neuronal and Glial Neurofascins Differentially Affects Node of Ranvier Maintenance and Myelinated Axon Function.
Volume: 11
Pages: 11
Publication
First Author: Chen L
Year: 2015
Journal: J Biol Chem
Title: Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis.
Volume: 290
Issue: 47
Pages: 28097-106
Publication
First Author: Terauchi A
Year: 2020
Journal: Neuroreport
Title: Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia.
Volume: 31
Issue: 2
Pages: 125-130
Publication
First Author: Deisseroth K
Year: 2006
Journal: J Neurosci
Title: Next-generation optical technologies for illuminating genetically targeted brain circuits.
Volume: 26
Issue: 41
Pages: 10380-6
Publication  
First Author: Shadrach JL
Year: 2018
Journal: eNeuro
Title: Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction.
Volume: 5
Issue: 3
Publication
First Author: Bento-Abreu A
Year: 2018
Journal: Hum Mol Genet
Title: Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.
Volume: 27
Issue: 7
Pages: 1276-1289
Publication
First Author: Rué L
Year: 2019
Journal: Sci Rep
Title: Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis.
Volume: 9
Issue: 1
Pages: 14112
Publication
First Author: Baron O
Year: 2019
Journal: Sci Rep
Title: Fat cadherins in mouse models of degenerative ataxias.
Volume: 9
Issue: 1
Pages: 16155
Publication
First Author: Franquinho F
Year: 2017
Journal: Cereb Cortex
Title: The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling.
Volume: 27
Issue: 3
Pages: 1732-1747
Publication
First Author: Nemtsova Y
Year: 2018
Journal: PLoS One
Title: Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis.
Volume: 13
Issue: 2
Pages: e0192286
Publication
First Author: Dvoriantchikova G
Year: 2018
Journal: Sci Rep
Title: Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells.
Volume: 8
Issue: 1
Pages: 5797
Publication
First Author: Norwood J
Year: 2014
Journal: J Biol Chem
Title: Histone deacetylase 3 is necessary for proper brain development.
Volume: 289
Issue: 50
Pages: 34569-82
Publication
First Author: Mota Vieira M
Year: 2020
Journal: Cell Rep
Title: An Epilepsy-Associated GRIN2A Rare Variant Disrupts CaMKIIα Phosphorylation of GluN2A and NMDA Receptor Trafficking.
Volume: 32
Issue: 9
Pages: 108104
Publication
First Author: Delerue F
Year: 2014
Journal: Transgenic Res
Title: Inducible, tightly regulated and non-leaky neuronal gene expression in mice.
Volume: 23
Issue: 2
Pages: 225-33
Publication
First Author: Yu J
Year: 2018
Journal: Mol Neurodegener
Title: Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice.
Volume: 13
Issue: 1
Pages: 10
Publication
First Author: Liang X
Year: 2011
Journal: J Clin Invest
Title: Signaling via the prostaglandin E₂ receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia.
Volume: 121
Issue: 11
Pages: 4362-71
Publication
First Author: Ye X
Year: 2017
Journal: J Neurosci
Title: Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Volume: 37
Issue: 10
Pages: 2639-2655
Publication
First Author: Kellendonk C
Year: 1999
Journal: J Mol Biol
Title: Inducible site-specific recombination in the brain.
Volume: 285
Issue: 1
Pages: 175-82
Publication
First Author: Ross JM
Year: 2018
Journal: J Neurosci
Title: Learning-Dependent and -Independent Enhancement of Mitral/Tufted Cell Glomerular Odor Responses Following Olfactory Fear Conditioning in Awake Mice.
Volume: 38
Issue: 20
Pages: 4623-4640
Publication
First Author: Ogg MC
Year: 2018
Journal: Nat Commun
Title: Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation.
Volume: 9
Issue: 1
Pages: 1868
Publication
First Author: Lu WJ
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration.
Volume: 115
Issue: 2
Pages: E200-E209
Publication
First Author: Cichon J
Year: 2015
Journal: Nature
Title: Branch-specific dendritic Ca(2+) spikes cause persistent synaptic plasticity.
Volume: 520
Issue: 7546
Pages: 180-5