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Search results 1 to 100 out of 135 for Tigar

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
57103 | TIGAR
Type: gene
Organism: human
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Gene
615392 | TIGAR
Type: gene
Organism: cattle
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Gene
419040 | TIGAR
Type: gene
Organism: chicken
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Gene
721886 | TIGAR
Type: gene
Organism: macaque, rhesus
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Gene
100145723 | tigar
Type: gene
Organism: frog, western clawed
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Gene
502894 | Tigar
Type: gene
Organism: rat
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Gene
486736 | TIGAR
Type: gene
Organism: dog, domestic
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Gene
466924 | TIGAR
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2442752 | Tigar
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23726973 | J:198650
First Author: Cheung EC
Year: 2013
Journal: Dev Cell
Title: TIGAR is required for efficient intestinal regeneration and tumorigenesis.
Volume: 25
Issue: 5
Pages: 463-77
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Publication
20935145 | J:167245
First Author: Kimata M
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.
Volume: 299
Issue: 6
Pages: H1908-16
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Publication
24872551 | J:211335
First Author: Li M
Year: 2014
Journal: J Neurosci
Title: A TIGAR-regulated metabolic pathway is critical for protection of brain ischemia.
Volume: 34
Issue: 22
Pages: 7458-71
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Publication
22044588 | J:183674
First Author: Hoshino A
Year: 2012
Journal: J Mol Cell Cardiol
Title: p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.
Volume: 52
Issue: 1
Pages: 175-84
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Publication
35441828 | J:324753
First Author: He X
Year: 2022
Journal: Physiol Rep
Title: TIGAR deficiency sensitizes angiotensin-II-induced renal fibrosis and glomerular injury.
Volume: 10
Issue: 8
Pages: e15234
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Publication
38397106 | J:345711
 
First Author: He X
Year: 2024
Journal: Int J Mol Sci
Title: TIGAR Deficiency Blunts Angiotensin-II-Induced Cardiac Hypertrophy in Mice.
Volume: 25
Issue: 4
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Publication
30978385 | J:295566
 
First Author: Zhang DM
Year: 2019
Journal: Free Radic Biol Med
Title: TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury.
Volume: 137
Pages: 13-23
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Publication
26247727 | J:312562
 
First Author: Lee P
Year: 2015
Journal: Cell Death Dis
Title: p53- and p73-independent activation of TIGAR expression in vivo.
Volume: 6
Pages: e1842
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Publication
30726106 | J:292341
First Author: Geng J
Year: 2019
Journal: FASEB J
Title: TIGAR regulates mitochondrial functions through SIRT1-PGC1α pathway and translocation of TIGAR into mitochondria in skeletal muscle.
Volume: 33
Issue: 5
Pages: 6082-6098
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Publication
32946259 | J:299844
First Author: Yamanaka R
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: TIGAR reduces smooth muscle cell autophagy to prevent pulmonary hypertension.
Volume: 319
Issue: 5
Pages: H1087-H1096
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Publication
29650758 | J:263682
First Author: Tang Y
Year: 2018
Journal: J Biol Chem
Title: The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC.
Volume: 293
Issue: 20
Pages: 7578-7591
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Publication
35621078 | J:335006
First Author: He X
Year: 2022
Journal: J Cell Physiol
Title: Knockout of TIGAR enhances myocardial phosphofructokinase activity and preserves diastolic function in heart failure.
Volume: 237
Issue: 8
Pages: 3317-3327
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Publication
31983610 | J:285699
First Author: Cheung EC
Year: 2020
Journal: Cancer Cell
Title: Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer.
Volume: 37
Issue: 2
Pages: 168-182.e4
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Publication
26219221 | J:321236
First Author: Cao L
Year: 2015
Journal: Neurosci Bull
Title: Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury.
Volume: 31
Issue: 5
Pages: 527-40
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Publication
35576689 | J:325125
 
First Author: Liu M
Year: 2022
Journal: Redox Biol
Title: TIGAR alleviates oxidative stress in brain with extended ischemia via a pentose phosphate pathway-independent manner.
Volume: 53
Pages: 102323
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Publication
35254259 | J:324752
   
First Author: Tang Y
Year: 2022
Journal: Elife
Title: TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling.
Volume: 11
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Publication
30901275 | J:301977
First Author: Okawa Y
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Ablation of cardiac TIGAR preserves myocardial energetics and cardiac function in the pressure overload heart failure model.
Volume: 316
Issue: 6
Pages: H1366-H1377
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Publication
24509157 | J:211920
 
First Author: Zhang H
Year: 2014
Journal: Free Radic Biol Med
Title: Radiosensitization of glioma cells by TP53-induced glycolysis and apoptosis regulator knockdown is dependent on thioredoxin-1 nuclear translocation.
Volume: 69
Pages: 239-48
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Publication
24423178 | J:211610
First Author: Gerin I
Year: 2014
Journal: Biochem J
Title: Identification of TP53-induced glycolysis and apoptosis regulator (TIGAR) as the phosphoglycolate-independent 2,3-bisphosphoglycerate phosphatase.
Volume: 458
Issue: 3
Pages: 439-48
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Publication
26679840 | J:227691
First Author: Cheung EC
Year: 2016
Journal: Genes Dev
Title: Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine.
Volume: 30
Issue: 1
Pages: 52-63
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UniProt Feature
UniProt Feature
Begin: 1
Description: Fructose-2,6-bisphosphatase TIGAR
Type: chain
End: 269
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Protein Coding Gene
MGP_CAROLIEiJ_G0028895 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442752 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030975 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031119 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030110 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022656 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029939 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:6383874
Age: postnatal day 10
Image: S4
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:6383874
Age: postnatal day 10
Image: S4
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:6383874
Age: postnatal day 10
Image: S4
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:6383874
Age: postnatal day 10
Image: S4
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6383880
Age: postnatal day 10
Image: 6
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6383880
Age: postnatal day 10
Image: 6
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6383880
Age: postnatal day 10
Image: 6
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6383880
Age: postnatal day 10
Image: 6
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383885
Age: postnatal day 10
Image: 8
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383885
Age: postnatal day 10
Image: 8
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383885
Age: postnatal day 10
Image: 8
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383885
Age: postnatal day 10
Image: 8
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6383895
Age: postnatal day 10
Image: 9
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6383895
Age: postnatal day 10
Image: 9
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6383895
Age: postnatal day 10
Image: 9
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6383895
Age: postnatal day 10
Image: 9
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6383900
Age: embryonic day 14.5
Image: S5
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6383900
Age: embryonic day 14.5
Image: S5
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6383900
Age: embryonic day 14.5
Image: S5
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 3
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6383854
Assay Type: RT-PCR
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:6383906
Age: postnatal day 10
Image: S6
Specimen Label: 4
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7264672
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7264691
Age: embryonic day 8.25
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7264672
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7264691
Age: embryonic day 8.25
Specimen Label: Jmjd5 delta/delta
Detected: true
Specimen Num: 2
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Publication
8596934 | J:32136
First Author: Forsthuber T
Year: 1996
Journal: Science
Title: Induction of TH1 and TH2 immunity in neonatal mice.
Volume: 271
Issue: 5256
Pages: 1728-30
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Publication
30977208 | J:291315
First Author: Li X
Year: 2019
Journal: Stem Cells
Title: p53-TP53-Induced Glycolysis Regulator Mediated Glycolytic Suppression Attenuates DNA Damage and Genomic Instability in Fanconi Anemia Hematopoietic Stem Cells.
Volume: 37
Issue: 7
Pages: 937-947
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Publication
33512431 | J:307794
First Author: Domostegui A
Year: 2021
Journal: Blood
Title: Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.
Volume: 137
Issue: 24
Pages: 3351-3364
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Publication
28425994 | J:254425
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
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Publication
24013501 | J:201153
First Author: Hamard PJ
Year: 2013
Journal: Genes Dev
Title: The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo.
Volume: 27
Issue: 17
Pages: 1868-85
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Publication
26334721 | J:268858
First Author: Ishimura A
Year: 2016
Journal: Cell Tissue Res
Title: Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.
Volume: 363
Issue: 3
Pages: 723-33
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
10725249 | J:60984
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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