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Search results 1 to 100 out of 100 for Tlk2

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
11011 | TLK2
Type: gene
Organism: human
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Gene
780168 | tlk2
Type: gene
Organism: frog, western clawed
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Gene
303592 | Tlk2
Type: gene
Organism: rat
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Gene
490915 | TLK2
Type: gene
Organism: dog, domestic
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Gene
468207 | TLK2
Type: gene
Organism: chimpanzee
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Gene
534705 | TLK2
Type: gene
Organism: cattle
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Gene
419949 | TLK2
Type: gene
Organism: chicken
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Gene
407732 | tlk2
Type: gene
Organism: zebrafish
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Gene
716528 | TLK2
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR027086 | TLK2
Type: Family
Description: This entry represents the serine/threonine-protein kinase TOUSLED- like 2 (TLK2) protein (). TLK2 is involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. It phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. It acts as a negative regulator of amino acid starvation-induced autophagy [].
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Protein Coding Gene
MGI:1346023 | Tlk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10092119 | J:53339
First Author: Shalom S
Year: 1999
Journal: Mol Reprod Dev
Title: Tlk, a novel evolutionarily conserved murine serine threonine kinase, encodes multiple testis transcripts.
Volume: 52
Issue: 4
Pages: 392-405
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Protein
Q6NZC4
Organism: Mus musculus/domesticus
Length: 657  
Fragment?: true
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Protein
F6XSD0
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: true
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Protein
D6RHM1
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
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Protein
B7ZC84
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Protein
Q3TTG3
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
O55047
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
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Protein
B7ZC85
Organism: Mus musculus/domesticus
Length: 633  
Fragment?: false
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Protein
B1ASU9
Organism: Mus musculus/domesticus
Length: 750  
Fragment?: false
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Protein
P70320
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Publication
30655559 | J:284022
First Author: Correia SP
Year: 2019
Journal: Sci Rep
Title: The circadian E3 ligase complex SCFFBXL3+CRY targets TLK2.
Volume: 9
Issue: 1
Pages: 198
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Publication
38498025 | J:351320
First Author: Lin HY
Year: 2024
Journal: Blood
Title: The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.
Volume: 143
Issue: 26
Pages: 2749-2762
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Publication
28708136 | J:268910
First Author: Segura-Bayona S
Year: 2017
Journal: Cell Death Differ
Title: Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.
Volume: 24
Issue: 11
Pages: 1872-1885
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Protein Coding Gene
MGP_CAROLIEiJ_G0017300 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019251 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019225 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1346023 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019136 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018638 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018429 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018143 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10455159 | J:57061
First Author: Zhang S
Year: 1999
Journal: J Biol Chem
Title: Nuclear localization of protein kinase U-alpha is regulated by 14-3-3.
Volume: 274
Issue: 35
Pages: 24865-72
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1346818
Age: embryonic day 7.0
Image: 3
Specimen Label: Day 7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1346818
Age: embryonic day 11.0
Image: 3
Specimen Label: Day 11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1346818
Age: embryonic day 15.0
Image: 3
Specimen Label: Day 15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1346818
Age: embryonic day 17.0
Image: 3
Specimen Label: Day 17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Skeletal musc.
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:1346817
Assay Type: Northern blot
Annotation Date: 1999-11-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1346820
Age: postnatal adult
Image: 3
Specimen Label: Testes
Detected: true
Specimen Num: 8
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Publication
28535374 | J:255302
First Author: Liu H
Year: 2017
Journal: Dev Cell
Title: Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Volume: 41
Issue: 4
Pages: 392-407.e6
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Publication
27782176 | J:278187
 
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 198
Description: Phosphoserine; by TLK2
Type: modified residue
End: 198
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UniProt Feature
UniProt Feature
Begin: 192
Description: Phosphoserine; by TLK2
Type: modified residue
End: 192
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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