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Search results 1 to 100 out of 195 for Tlr1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
7096 | TLR1
Type: gene
Organism: human
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Gene
100495171 | tlr1
Type: gene
Organism: frog, western clawed
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Gene
488834 | TLR1
Type: gene
Organism: dog, domestic
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Gene
305354 | Tlr1
Type: gene
Organism: rat
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Gene
461167 | TLR1
Type: gene
Organism: chimpanzee
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Gene
574090 | TLR1
Type: gene
Organism: cattle
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Gene
403127 | tlr1
Type: gene
Organism: zebrafish
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Gene
574289 | TLR1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1341295 | Tlr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR027190 | TLR1
Type: Family
Description: Toll-like receptor 1 (TLR1) participates in the innate immune response to microbial agents. TLR1 cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides [, ]. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
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Publication
12091878 | J:95726
First Author: Alexopoulou L
Year: 2002
Journal: Nat Med
Title: Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice.
Volume: 8
Issue: 8
Pages: 878-84
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Publication
12077222 | J:103395
First Author: Takeuchi O
Year: 2002
Journal: J Immunol
Title: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.
Volume: 169
Issue: 1
Pages: 10-4
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Publication
17785827 | J:152040
First Author: Vallois D
Year: 2007
Journal: J Immunol
Title: The type 1 diabetes locus Idd6 controls TLR1 expression.
Volume: 179
Issue: 6
Pages: 3896-903
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Publication
22778390 | J:189165
First Author: DePaolo RW
Year: 2012
Journal: J Exp Med
Title: A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.
Volume: 209
Issue: 8
Pages: 1437-44
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Publication
29794015 | J:263317
First Author: Kamdar K
Year: 2018
Journal: J Immunol
Title: Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation.
Volume: 201
Issue: 1
Pages: 230-242
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Protein
Q9EPQ1
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
Q6A0E8
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: true
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Protein
B9EJ46
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Publication
28684329 | J:252734
First Author: Jang YH
Year: 2017
Journal: J Invest Dermatol
Title: House Dust Mite Increases pro-Th2 Cytokines IL-25 and IL-33 via the Activation of TLR1/6 Signaling.
Volume: 137
Issue: 11
Pages: 2354-2361
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Publication
34497333 | J:359922
First Author: Baumann A
Year: 2021
Journal: Sci Rep
Title: Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease.
Volume: 11
Issue: 1
Pages: 17815
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Publication
10231569 | J:54928
First Author: Takeuchi O
Year: 1999
Journal: Gene
Title: TLR6: A novel member of an expanding toll-like receptor family.
Volume: 231
Issue: 1-2
Pages: 59-65
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Publication
11095740 | J:82453
First Author: Ozinsky A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Volume: 97
Issue: 25
Pages: 13766-71
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Publication
18195069 | J:131147
First Author: Yang D
Year: 2008
Journal: J Exp Med
Title: Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
Volume: 205
Issue: 1
Pages: 79-90
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Publication
11081518 | J:114793
First Author: Xu Y
Year: 2000
Journal: Nature
Title: Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Volume: 408
Issue: 6808
Pages: 111-5
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Publication
17664270 | J:125281
First Author: Izadi H
Year: 2007
Journal: Infect Immun
Title: c-Jun N-terminal kinase 1 is required for Toll-like receptor 1 gene expression in macrophages.
Volume: 75
Issue: 10
Pages: 5027-34
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Publication
17998391 | J:128513
First Author: Takahashi K
Year: 2007
Journal: J Exp Med
Title: A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses.
Volume: 204
Issue: 12
Pages: 2963-76
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Publication
22822027 | J:188042
First Author: Curtiss LK
Year: 2012
Journal: J Lipid Res
Title: Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.
Volume: 53
Issue: 10
Pages: 2126-32
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Publication
25246533 | J:296302
First Author: Ammerdorffer A
Year: 2015
Journal: J Infect Dis
Title: Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.
Volume: 211
Issue: 6
Pages: 978-87
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Publication
17595379 | J:141916
First Author: Chang S
Year: 2007
Journal: J Leukoc Biol
Title: Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
Volume: 82
Issue: 3
Pages: 479-87
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Publication
21998742 | J:178115
First Author: Oosting M
Year: 2011
Journal: PLoS One
Title: TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.
Volume: 6
Issue: 10
Pages: e25998
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Publication
20478617 | J:160689
First Author: Leng CH
Year: 2010
Journal: Mol Immunol
Title: A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide.
Volume: 47
Issue: 11-12
Pages: 2015-21
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Publication
11739528 | J:118414
First Author: Henneke P
Year: 2001
Journal: J Immunol
Title: Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Volume: 167
Issue: 12
Pages: 7069-76
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Publication
32652111 | J:299870
 
First Author: Monlish DA
Year: 2020
Journal: Exp Hematol
Title: TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.
Volume: 88
Pages: 42-55
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Publication
24014382 | J:347943
First Author: Vinnakota K
Year: 2013
Journal: Neuro Oncol
Title: Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.
Volume: 15
Issue: 11
Pages: 1457-68
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Publication
19936231 | J:155404
First Author: Abplanalp AL
Year: 2009
Journal: PLoS One
Title: TLR-dependent control of Francisella tularensis infection and host inflammatory responses.
Volume: 4
Issue: 11
Pages: e7920
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Protein Coding Gene
MGP_CAROLIEiJ_G0027239 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029545 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1341295 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028400 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017021 | -
Type: protein_coding_gene
Organism: Mus pahari
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:5751715
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:5751715
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751715
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5751715
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:5751715
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751715
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751715
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751757
Age: postnatal week 8
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751757
Age: postnatal week 8
Specimen Label: TLR2KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7334818
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:7334818
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7334818
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7334818
Age: embryonic day 16.0
Image: 1
Specimen Label: E16
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7334818
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334818
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334818
Age: embryonic day 19.0
Image: 1
Specimen Label: E19
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7334818
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 4
Image: 1
Specimen Label: P4
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 8
Image: 1
Specimen Label: P8
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 12
Image: 1
Specimen Label: P12
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal month 5
Image: 1
Specimen Label: P5m
Detected: true
Specimen Num: 12
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Publication
10431187 | J:56658
First Author: Qureshi ST
Year: 1999
Journal: Trends Genet
Title: Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes.
Volume: 15
Issue: 8
Pages: 291-4
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Publication
21217015 | J:169172
First Author: Zhang Y
Year: 2011
Journal: J Immunol
Title: TLR1/TLR2 agonist induces tumor regression by reciprocal modulation of effector and regulatory T cells.
Volume: 186
Issue: 4
Pages: 1963-9
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Publication
24683188 | J:209973
First Author: Shen KY
Year: 2014
Journal: J Immunol
Title: Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.
Volume: 192
Issue: 9
Pages: 4233-41
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Publication
16455646 | J:111575
First Author: Buwitt-Beckmann U
Year: 2006
Journal: J Biol Chem
Title: TLR1- and TLR6-independent recognition of bacterial lipopeptides.
Volume: 281
Issue: 14
Pages: 9049-57
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Publication
27650608 | J:238509
First Author: Doi T
Year: 2017
Journal: J Invest Dermatol
Title: Importance of Water Content of the Stratum Corneum in Mouse Models for Contact Hypersensitivity.
Volume: 137
Issue: 1
Pages: 151-158
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Publication
16622218 | J:108092
First Author: Katz J
Year: 2006
Journal: Infect Immun
Title: Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.
Volume: 74
Issue: 5
Pages: 2809-16
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Publication
18391010 | J:136127
First Author: Loof TG
Year: 2008
Journal: Infect Immun
Title: Immune recognition of Streptococcus pyogenes by dendritic cells.
Volume: 76
Issue: 6
Pages: 2785-92
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Publication
25124037 | J:217074
First Author: Hanihara-Tatsuzawa F
Year: 2014
Journal: J Biol Chem
Title: Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ.
Volume: 289
Issue: 45
Pages: 30925-36
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Publication
16001129 | J:101680
First Author: Beutler B
Year: 2005
Journal: Immunogenetics
Title: The Toll-like receptors: analysis by forward genetic methods.
Volume: 57
Issue: 6
Pages: 385-92
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Publication
18981243 | J:143767
First Author: Ribes S
Year: 2009
Journal: Infect Immun
Title: Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells.
Volume: 77
Issue: 1
Pages: 557-64
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Publication
19362712 | J:149492
First Author: Drage MG
Year: 2009
Journal: Cell Immunol
Title: TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Volume: 258
Issue: 1
Pages: 29-37
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Publication
23477738 | J:196201
First Author: Speer T
Year: 2013
Journal: Immunity
Title: Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.
Volume: 38
Issue: 4
Pages: 754-68
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Publication
23077245 | J:193776
First Author: Gaddis DE
Year: 2013
Journal: J Leukoc Biol
Title: Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.
Volume: 93
Issue: 1
Pages: 21-31
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Publication
17004992 | J:135842
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
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Publication
19019963 | J:153388
First Author: Murawski MR
Year: 2009
Journal: J Virol
Title: Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.
Volume: 83
Issue: 3
Pages: 1492-500
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Publication
21685327 | J:178028
First Author: Miranda-Hernandez S
Year: 2011
Journal: J Immunol
Title: Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Volume: 187
Issue: 2
Pages: 791-804
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Publication
16378096 | J:112607
First Author: Wang Y
Year: 2006
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