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Search results 1 to 100 out of 190 for Tlr1

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Toll-like receptor 1 (TLR1) participates in the innate immune response to microbial agents. TLR1 cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides [, ]. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Publication
First Author: Alexopoulou L
Year: 2002
Journal: Nat Med
Title: Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice.
Volume: 8
Issue: 8
Pages: 878-84
Publication
First Author: Takeuchi O
Year: 2002
Journal: J Immunol
Title: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.
Volume: 169
Issue: 1
Pages: 10-4
Publication
First Author: Vallois D
Year: 2007
Journal: J Immunol
Title: The type 1 diabetes locus Idd6 controls TLR1 expression.
Volume: 179
Issue: 6
Pages: 3896-903
Publication
First Author: DePaolo RW
Year: 2012
Journal: J Exp Med
Title: A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.
Volume: 209
Issue: 8
Pages: 1437-44
Publication
First Author: Kamdar K
Year: 2018
Journal: J Immunol
Title: Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation.
Volume: 201
Issue: 1
Pages: 230-242
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
Publication
First Author: Jang YH
Year: 2017
Journal: J Invest Dermatol
Title: House Dust Mite Increases pro-Th2 Cytokines IL-25 and IL-33 via the Activation of TLR1/6 Signaling.
Volume: 137
Issue: 11
Pages: 2354-2361
Publication
First Author: Takeuchi O
Year: 1999
Journal: Gene
Title: TLR6: A novel member of an expanding toll-like receptor family.
Volume: 231
Issue: 1-2
Pages: 59-65
Publication
First Author: Ozinsky A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Volume: 97
Issue: 25
Pages: 13766-71
Publication
First Author: Yang D
Year: 2008
Journal: J Exp Med
Title: Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
Volume: 205
Issue: 1
Pages: 79-90
Publication
First Author: Izadi H
Year: 2007
Journal: Infect Immun
Title: c-Jun N-terminal kinase 1 is required for Toll-like receptor 1 gene expression in macrophages.
Volume: 75
Issue: 10
Pages: 5027-34
Publication
First Author: Xu Y
Year: 2000
Journal: Nature
Title: Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Volume: 408
Issue: 6808
Pages: 111-5
Publication
First Author: Takahashi K
Year: 2007
Journal: J Exp Med
Title: A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses.
Volume: 204
Issue: 12
Pages: 2963-76
Publication
First Author: Curtiss LK
Year: 2012
Journal: J Lipid Res
Title: Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.
Volume: 53
Issue: 10
Pages: 2126-32
Publication
First Author: Ammerdorffer A
Year: 2015
Journal: J Infect Dis
Title: Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.
Volume: 211
Issue: 6
Pages: 978-87
Publication
First Author: Chang S
Year: 2007
Journal: J Leukoc Biol
Title: Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
Volume: 82
Issue: 3
Pages: 479-87
Publication
First Author: Oosting M
Year: 2011
Journal: PLoS One
Title: TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.
Volume: 6
Issue: 10
Pages: e25998
Publication
First Author: Henneke P
Year: 2001
Journal: J Immunol
Title: Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Volume: 167
Issue: 12
Pages: 7069-76
Publication
First Author: Leng CH
Year: 2010
Journal: Mol Immunol
Title: A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide.
Volume: 47
Issue: 11-12
Pages: 2015-21
Publication  
First Author: Monlish DA
Year: 2020
Journal: Exp Hematol
Title: TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.
Volume: 88
Pages: 42-55
Publication
First Author: Abplanalp AL
Year: 2009
Journal: PLoS One
Title: TLR-dependent control of Francisella tularensis infection and host inflammatory responses.
Volume: 4
Issue: 11
Pages: e7920
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:5751715
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:5751715
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751715
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5751715
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:5751715
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751715
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751715
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751757
Age: postnatal week 8
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751585
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751757
Age: postnatal week 8
Specimen Label: TLR2KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7334818
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:7334818
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7334818
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7334818
Age: embryonic day 16.0
Image: 1
Specimen Label: E16
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7334818
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334818
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334818
Age: embryonic day 19.0
Image: 1
Specimen Label: E19
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7334818
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 4
Image: 1
Specimen Label: P4
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 8
Image: 1
Specimen Label: P8
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal day 12
Image: 1
Specimen Label: P12
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7334809
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334818
Age: postnatal month 5
Image: 1
Specimen Label: P5m
Detected: true
Specimen Num: 12
Publication
First Author: Qureshi ST
Year: 1999
Journal: Trends Genet
Title: Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes.
Volume: 15
Issue: 8
Pages: 291-4
Publication
First Author: Zhang Y
Year: 2011
Journal: J Immunol
Title: TLR1/TLR2 agonist induces tumor regression by reciprocal modulation of effector and regulatory T cells.
Volume: 186
Issue: 4
Pages: 1963-9
Publication
First Author: Shen KY
Year: 2014
Journal: J Immunol
Title: Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.
Volume: 192
Issue: 9
Pages: 4233-41
Publication
First Author: Buwitt-Beckmann U
Year: 2006
Journal: J Biol Chem
Title: TLR1- and TLR6-independent recognition of bacterial lipopeptides.
Volume: 281
Issue: 14
Pages: 9049-57
Publication
First Author: Doi T
Year: 2017
Journal: J Invest Dermatol
Title: Importance of Water Content of the Stratum Corneum in Mouse Models for Contact Hypersensitivity.
Volume: 137
Issue: 1
Pages: 151-158
Publication
First Author: Loof TG
Year: 2008
Journal: Infect Immun
Title: Immune recognition of Streptococcus pyogenes by dendritic cells.
Volume: 76
Issue: 6
Pages: 2785-92
Publication
First Author: Katz J
Year: 2006
Journal: Infect Immun
Title: Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.
Volume: 74
Issue: 5
Pages: 2809-16
Publication
First Author: Hanihara-Tatsuzawa F
Year: 2014
Journal: J Biol Chem
Title: Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ.
Volume: 289
Issue: 45
Pages: 30925-36
Publication
First Author: Beutler B
Year: 2005
Journal: Immunogenetics
Title: The Toll-like receptors: analysis by forward genetic methods.
Volume: 57
Issue: 6
Pages: 385-92
Publication
First Author: Ribes S
Year: 2009
Journal: Infect Immun
Title: Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells.
Volume: 77
Issue: 1
Pages: 557-64
Publication
First Author: Drage MG
Year: 2009
Journal: Cell Immunol
Title: TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Volume: 258
Issue: 1
Pages: 29-37
Publication
First Author: West AP
Year: 2011
Journal: Nature
Title: TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
Volume: 472
Issue: 7344
Pages: 476-80
Publication
First Author: Murawski MR
Year: 2009
Journal: J Virol
Title: Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.
Volume: 83
Issue: 3
Pages: 1492-500
Publication
First Author: Miranda-Hernandez S
Year: 2011
Journal: J Immunol
Title: Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Volume: 187
Issue: 2
Pages: 791-804
Publication
First Author: Gaddis DE
Year: 2013
Journal: J Leukoc Biol
Title: Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.
Volume: 93
Issue: 1
Pages: 21-31
Publication
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
Publication
First Author: Speer T
Year: 2013
Journal: Immunity
Title: Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.
Volume: 38
Issue: 4
Pages: 754-68
Publication
First Author: Wang Y
Year: 2006
Journal: Nat Immunol
Title: Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.
Volume: 7
Issue: 2
Pages: 139-47
Publication
First Author: Jiang D
Year: 2005
Journal: Nat Med
Title: Regulation of lung injury and repair by Toll-like receptors and hyaluronan.
Volume: 11
Issue: 11
Pages: 1173-9
Publication
First Author: Medina EA
Year: 2010
Journal: J Immunol
Title: Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.
Volume: 185
Issue: 12
Pages: 7562-72
Publication
First Author: Okun E
Year: 2010
Journal: J Neurochem
Title: TLR2 activation inhibits embryonic neural progenitor cell proliferation.
Volume: 114
Issue: 2
Pages: 462-74
Publication
First Author: Enoksson M
Year: 2011
Journal: J Immunol
Title: Mast cells as sensors of cell injury through IL-33 recognition.
Volume: 186
Issue: 4
Pages: 2523-8
Publication
First Author: Togbe D
Year: 2007
Journal: Am J Pathol
Title: Murine cerebral malaria development is independent of toll-like receptor signaling.
Volume: 170
Issue: 5
Pages: 1640-8
Publication
First Author: Chen CJ
Year: 2007
Journal: Nat Med
Title: Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.
Volume: 13
Issue: 7
Pages: 851-6
Publication
First Author: Kumar H
Year: 2009
Journal: Biochem J
Title: Pathogen recognition in the innate immune response.
Volume: 420
Issue: 1
Pages: 1-16
Publication
First Author: Seimon TA
Year: 2010
Journal: Cell Metab
Title: Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress.
Volume: 12
Issue: 5
Pages: 467-82
Publication  
First Author: Martino MM
Year: 2016
Journal: Nat Commun
Title: Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.
Volume: 7
Pages: 11051
Publication
First Author: Kim S
Year: 2009
Journal: Nature
Title: Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.
Volume: 457
Issue: 7225
Pages: 102-6
Publication
First Author: Drennan MB
Year: 2005
Journal: J Immunol
Title: The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.
Volume: 175
Issue: 4
Pages: 2501-9
Publication
First Author: Alugupalli KR
Year: 2007
Journal: J Immunol
Title: MyD88- and Bruton's tyrosine kinase-mediated signals are essential for T cell-independent pathogen-specific IgM responses.
Volume: 178
Issue: 6
Pages: 3740-9