Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Toll-like receptor 5 (TLR5) participates in the innate immune response to microbial agents. Toll-like receptors are classified into various types, depending on their primary sequence and types of ligands they recognise. TLR5 mediates detection of bacterial flagellins, both from from both Gram-positive and Gram-negative bacteria [, ]. TLR5 signaling acts via MYD88. In MyD88-dependent signaling, ligand binding to TLR triggers sequential recruitment of MyD88, members of IRAK (interleukin-1 receptora ssociated kinase) family and TRAF6, that results in nuclear factor (NF)-kB activation and induction of cytokine secretion and production of inflammatory cytokines including IL-8 and TNF-alpha. Genetic variation in TLR5 have been associated with systemic lupus erythematosus, an inflammatory and often febrile multisystemic disorder of connective tissue []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ivison SM |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin. |
Volume: |
178 |
Issue: |
9 |
Pages: |
5735-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parkunan SM |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Role of TLR5 and flagella in bacillus intraocular infection. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e100543 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vijay-Kumar M |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
Deletion of TLR5 results in spontaneous colitis in mice. |
Volume: |
117 |
Issue: |
12 |
Pages: |
3909-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yiu JHC |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
TLR5 Supports Development of Placental Labyrinthine Zone in Mice. |
Volume: |
9 |
|
Pages: |
711253 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi F |
Year: |
2001 |
Journal: |
Nature |
Title: |
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. |
Volume: |
410 |
Issue: |
6832 |
Pages: |
1099-103 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawn TR |
Year: |
2005 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus. |
Volume: |
102 |
Issue: |
30 |
Pages: |
10593-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gonzalez C |
Year: |
2023 |
Journal: |
Commun Biol |
Title: |
TLR5 agonists enhance anti-tumor immunity and overcome resistance to immune checkpoint therapy. |
Volume: |
6 |
Issue: |
1 |
Pages: |
31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hossain MS |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Recombinant TLR5 agonist CBLB502 promotes NK cell-mediated anti-CMV immunity in mice. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e96165 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
TLR5 mediates CD172α(+) intestinal lamina propria dendritic cell induction of Th17 cells. |
Volume: |
6 |
|
Pages: |
22040 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holzapfel M |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella. |
Volume: |
11 |
|
Pages: |
2007 |
|
•
•
•
•
•
|
Publication |
First Author: |
Letran SE |
Year: |
2011 |
Journal: |
Eur J Immunol |
Title: |
TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity. |
Volume: |
41 |
Issue: |
1 |
Pages: |
29-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito H |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Role of TLR5 in inflammation and tissue damage after intestinal ischemia-reperfusion injury. |
Volume: |
519 |
Issue: |
1 |
Pages: |
15-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saha S |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Blocking of the TLR5 activation domain hampers protective potential of flagellin DNA vaccine. |
Volume: |
179 |
Issue: |
2 |
Pages: |
1147-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vijay-Kumar M |
Year: |
2010 |
Journal: |
Eur J Immunol |
Title: |
TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. |
Volume: |
40 |
Issue: |
12 |
Pages: |
3528-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haderski GJ |
Year: |
2020 |
Journal: |
PLoS One |
Title: |
TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects. |
Volume: |
15 |
Issue: |
2 |
Pages: |
e0227940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hussain S |
Year: |
2020 |
Journal: |
Elife |
Title: |
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata T |
Year: |
2012 |
Journal: |
Int Immunol |
Title: |
PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells. |
Volume: |
24 |
Issue: |
10 |
Pages: |
613-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Angers I |
Year: |
2006 |
Journal: |
Mamm Genome |
Title: |
Tlr5 is not primarily associated with susceptibility to Salmonella Typhimurium infection in MOLF/Ei mice. |
Volume: |
17 |
Issue: |
5 |
Pages: |
385-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ellenbroek GH |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness. |
Volume: |
7 |
|
Pages: |
42688 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2021 |
Journal: |
J Immunol Res |
Title: |
Role of TLR5 in the Translocation and Dissemination of Commensal Bacteria in the Intestine after Traumatic Hemorrhagic Shock. |
Volume: |
2021 |
|
Pages: |
6417658 |
|
•
•
•
•
•
|
Publication |
First Author: |
Janot L |
Year: |
2009 |
Journal: |
Eur J Immunol |
Title: |
Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin. |
Volume: |
39 |
Issue: |
6 |
Pages: |
1587-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Maele L |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. |
Volume: |
185 |
Issue: |
2 |
Pages: |
1177-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bates JT |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Enhanced antigen processing of flagellin fusion proteins promotes the antigen-specific CD8+ T cell response independently of TLR5 and MyD88. |
Volume: |
186 |
Issue: |
11 |
Pages: |
6255-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ali ASM |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection. |
Volume: |
7 |
Issue: |
1 |
Pages: |
11039 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
859
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
859
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
873
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
853
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
859
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kato K |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88. |
Volume: |
188 |
Issue: |
4 |
Pages: |
2014-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. |
Volume: |
185 |
Issue: |
7 |
Pages: |
4272-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thakur BK |
Year: |
2016 |
Journal: |
Nucleic Acids Res |
Title: |
Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms. |
Volume: |
44 |
Issue: |
12 |
Pages: |
5658-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Letran SE |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen. |
Volume: |
186 |
Issue: |
9 |
Pages: |
5406-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andersen-Nissen E |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. |
Volume: |
178 |
Issue: |
8 |
Pages: |
4717-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oh JZ |
Year: |
2014 |
Journal: |
Immunity |
Title: |
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. |
Volume: |
41 |
Issue: |
3 |
Pages: |
478-492 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mosquera MJ |
Year: |
2019 |
Journal: |
Sci Adv |
Title: |
Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome-mediated metabolic syndrome. |
Volume: |
5 |
Issue: |
3 |
Pages: |
eaav9788 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andersen-Nissen E |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. |
Volume: |
204 |
Issue: |
2 |
Pages: |
393-403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawn TR |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila. |
Volume: |
179 |
Issue: |
10 |
Pages: |
6981-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morris AE |
Year: |
2009 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia. |
Volume: |
297 |
Issue: |
6 |
Pages: |
L1112-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shim JU |
Year: |
2016 |
Journal: |
J Allergy Clin Immunol |
Title: |
Flagellin suppresses experimental asthma by generating regulatory dendritic cells and T cells. |
Volume: |
137 |
Issue: |
2 |
Pages: |
426-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birnie E |
Year: |
2019 |
Journal: |
Infect Immun |
Title: |
Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis. |
Volume: |
87 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jarchum I |
Year: |
2011 |
Journal: |
Infect Immun |
Title: |
Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis. |
Volume: |
79 |
Issue: |
4 |
Pages: |
1498-503 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pearson JA |
Year: |
2024 |
Journal: |
Front Immunol |
Title: |
TLR5-deficiency controls dendritic cell subset development in an autoimmune diabetes-susceptible model. |
Volume: |
15 |
|
Pages: |
1333967 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carapau D |
Year: |
2013 |
Journal: |
Infect Immun |
Title: |
Protective humoral immunity elicited by a needle-free malaria vaccine comprised of a chimeric Plasmodium falciparum circumsporozoite protein and a Toll-like receptor 5 agonist, flagellin. |
Volume: |
81 |
Issue: |
12 |
Pages: |
4350-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
Toll-like receptor 5 deficiency attenuates interstitial cardiac fibrosis and dysfunction induced by pressure overload by inhibiting inflammation and the endothelial-mesenchymal transition. |
Volume: |
1852 |
Issue: |
11 |
Pages: |
2456-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flores-Langarica A |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Systemic flagellin immunization stimulates mucosal CD103+ dendritic cells and drives Foxp3+ regulatory T cell and IgA responses in the mesenteric lymph node. |
Volume: |
189 |
Issue: |
12 |
Pages: |
5745-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nempont C |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity. |
Volume: |
181 |
Issue: |
3 |
Pages: |
2036-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uematsu S |
Year: |
2006 |
Journal: |
Nat Immunol |
Title: |
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. |
Volume: |
7 |
Issue: |
8 |
Pages: |
868-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han JH |
Year: |
2015 |
Journal: |
J Vet Sci |
Title: |
Decreased expression of Toll-like receptor 4 and 5 during progression of prostate transformation in transgenic adenocarcinoma of mouse prostate mice. |
Volume: |
16 |
Issue: |
3 |
Pages: |
281-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng T |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. |
Volume: |
7 |
Issue: |
4 |
Pages: |
e35918 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sebastiani G |
Year: |
2000 |
Journal: |
Genomics |
Title: |
Cloning and characterization of the murine toll-like receptor 5 (Tlr5) gene: sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice. |
Volume: |
64 |
Issue: |
3 |
Pages: |
230-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mett V |
Year: |
2018 |
Journal: |
Oncogene |
Title: |
Mobilan: a recombinant adenovirus carrying Toll-like receptor 5 self-activating cassette for cancer immunotherapy. |
Volume: |
37 |
Issue: |
4 |
Pages: |
439-449 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao Y |
Year: |
2017 |
Journal: |
J Leukoc Biol |
Title: |
Frontline Science: Nasal epithelial GM-CSF contributes to TLR5-mediated modulation of airway dendritic cells and subsequent IgA response. |
Volume: |
102 |
Issue: |
3 |
Pages: |
575-587 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chassaing B |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency. |
Volume: |
13 |
Issue: |
4 |
Pages: |
e0195310 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burdelya LG |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist. |
Volume: |
110 |
Issue: |
20 |
Pages: |
E1857-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu FS |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Flagellin stimulates protective lung mucosal immunity: role of cathelicidin-related antimicrobial peptide. |
Volume: |
185 |
Issue: |
2 |
Pages: |
1142-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamada H |
Year: |
2023 |
Journal: |
Sci Rep |
Title: |
Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers-Danlos syndrome. |
Volume: |
13 |
Issue: |
1 |
Pages: |
18490 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feuillet V |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. |
Volume: |
103 |
Issue: |
33 |
Pages: |
12487-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai MA |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Innate immune detection of flagellin positively and negatively regulates salmonella infection. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e72047 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sanders CJ |
Year: |
2009 |
Journal: |
Eur J Immunol |
Title: |
Induction of adaptive immunity by flagellin does not require robust activation of innate immunity. |
Volume: |
39 |
Issue: |
2 |
Pages: |
359-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huh JW |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5. |
Volume: |
111 |
Issue: |
19 |
Pages: |
7072-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng L |
Year: |
2016 |
Journal: |
Biol Reprod |
Title: |
Toll-like Receptors 4 and 5 Cooperatively Initiate the Innate Immune Responses to Uropathogenic Escherichia coli Infection in Mouse Epididymal Epithelial Cells. |
Volume: |
94 |
Issue: |
3 |
Pages: |
58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu ZZ |
Year: |
2015 |
Journal: |
Nat Med |
Title: |
Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. |
Volume: |
21 |
Issue: |
11 |
Pages: |
1326-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vijay-Kumar M |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. |
Volume: |
180 |
Issue: |
12 |
Pages: |
8280-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vijayan A |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin. |
Volume: |
205 |
Issue: |
10 |
Pages: |
2873-2882 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rutkowski MR |
Year: |
2015 |
Journal: |
Cancer Cell |
Title: |
Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. |
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27 |
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Year: |
2024 |
Journal: |
Immunity |
Title: |
Epithelial-derived interleukin-23 promotes oral mucosal immunopathology. |
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57 |
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4 |
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Publication |
First Author: |
Fulde M |
Year: |
2018 |
Journal: |
Nature |
Title: |
Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. |
Volume: |
560 |
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First Author: |
Garaude J |
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2012 |
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Sci Transl Med |
Title: |
Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. |
Volume: |
4 |
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First Author: |
Ramphal R |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin. |
Volume: |
181 |
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Publication |
First Author: |
Zhou Z |
Year: |
2020 |
Journal: |
Am J Pathol |
Title: |
Toll-Like Receptor 5 Signaling Ameliorates Liver Fibrosis by Inducing Interferon β-Modulated IL-1 Receptor Antagonist in Mice. |
Volume: |
190 |
Issue: |
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First Author: |
Anas AA |
Year: |
2016 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism. |
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First Author: |
Choi YJ |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells. |
Volume: |
285 |
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First Author: |
Riccioli A |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Sertoli cells initiate testicular innate immune responses through TLR activation. |
Volume: |
177 |
Issue: |
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First Author: |
Ifuku M |
Year: |
2020 |
Journal: |
Acta Neuropathol Commun |
Title: |
Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury. |
Volume: |
8 |
Issue: |
1 |
Pages: |
159 |
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First Author: |
Floyd M |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa. |
Volume: |
12 |
Issue: |
11 |
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First Author: |
Price AE |
Year: |
2018 |
Journal: |
Immunity |
Title: |
A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns. |
Volume: |
49 |
Issue: |
3 |
Pages: |
560-575.e6 |
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First Author: |
Brackett CM |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis. |
Volume: |
113 |
Issue: |
7 |
Pages: |
E874-83 |
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Publication |
First Author: |
Kuo PJ |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Metagenomic analysis of the effects of toll-like receptors on bacterial infection in the peritoneal cavity following cecum ligation and puncture in mice. |
Volume: |
14 |
Issue: |
7 |
Pages: |
e0220398 |
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Publication |
First Author: |
West TE |
Year: |
2009 |
Journal: |
Infect Immun |
Title: |
Toll-like receptor signaling in airborne Burkholderia thailandensis infection. |
Volume: |
77 |
Issue: |
12 |
Pages: |
5612-22 |
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First Author: |
López-Yglesias AH |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway. |
Volume: |
192 |
Issue: |
4 |
Pages: |
1587-96 |
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Publication |
First Author: |
Shin OS |
Year: |
2008 |
Journal: |
Infect Immun |
Title: |
Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction. |
Volume: |
76 |
Issue: |
6 |
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First Author: |
Lim JS |
Year: |
2015 |
Journal: |
Aging Cell |
Title: |
Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence. |
Volume: |
14 |
Issue: |
5 |
Pages: |
907-15 |
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Publication |
First Author: |
Wu H |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Expression patterns and functions of toll-like receptors in mouse sertoli cells. |
Volume: |
149 |
Issue: |
9 |
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4402-12 |
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First Author: |
Shu M |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Inhibition of MAPK and NF-κB signaling pathways alleviate carbon tetrachloride (CCl4)-induced liver fibrosis in Toll-like receptor 5 (TLR5) deficiency mice. |
Volume: |
471 |
Issue: |
1 |
Pages: |
233-9 |
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Publication |
First Author: |
Menon BB |
Year: |
2015 |
Journal: |
Mucosal Immunol |
Title: |
Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16. |
Volume: |
8 |
Issue: |
5 |
Pages: |
1000-8 |
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Publication |
First Author: |
Uematsu S |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. |
Volume: |
9 |
Issue: |
7 |
Pages: |
769-76 |
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Publication |
First Author: |
Descamps D |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing. |
Volume: |
109 |
Issue: |
5 |
Pages: |
1619-24 |
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Publication |
First Author: |
Metruccio MME |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa. |
Volume: |
7 |
Issue: |
1 |
Pages: |
13829 |
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Publication |
First Author: |
Shi Z |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Toll-like receptor 11 (TLR11) prevents Salmonella penetration into the murine Peyer patches. |
Volume: |
287 |
Issue: |
52 |
Pages: |
43417-23 |
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