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Search results 1 to 100 out of 274 for Tlr6

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Toll-like receptor 6 (TLR6) participates in the innate immune response to Gram-positive bacteria and fungi. TLRs recognize specific molecular patterns present only in micro-organisms. TLR1 and TLR6 are involved in the discrimination of a subtle difference between triacyl and diacyl lipopeptides through interaction with TLR2 []. Cooperatively with TLR2, TLR6 recognises mycoplasmal macrophage-activating lipopeptide-2 (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) []. TLR6 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [].
Publication
First Author: Takeuchi O
Year: 1999
Journal: Gene
Title: TLR6: A novel member of an expanding toll-like receptor family.
Volume: 231
Issue: 1-2
Pages: 59-65
Protein
Organism: Mus musculus
Length: 806  
Fragment?: false
Publication
First Author: Sugawara I
Year: 2003
Journal: Microbiol Immunol
Title: Mycobacterial infection in TLR2 and TLR6 knockout mice.
Volume: 47
Issue: 5
Pages: 327-36
Publication
First Author: Curtiss LK
Year: 2012
Journal: J Lipid Res
Title: Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.
Volume: 53
Issue: 10
Pages: 2126-32
Publication
First Author: Chen J
Year: 2015
Journal: PLoS Pathog
Title: Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection.
Volume: 11
Issue: 7
Pages: e1005053
Publication
First Author: Moreira AP
Year: 2011
Journal: J Clin Invest
Title: The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.
Volume: 121
Issue: 11
Pages: 4420-32
Publication
First Author: Bulut Y
Year: 2001
Journal: J Immunol
Title: Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
Volume: 167
Issue: 2
Pages: 987-94
Publication
First Author: Miranda-Hernandez S
Year: 2011
Journal: J Immunol
Title: Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Volume: 187
Issue: 2
Pages: 791-804
Publication
First Author: Takeda K
Year: 2002
Journal: J Endotoxin Res
Title: Recognition of lipopeptides by Toll-like receptors.
Volume: 8
Issue: 6
Pages: 459-63
Publication
First Author: Gomes MT
Year: 2016
Journal: J Leukoc Biol
Title: TLR9 is required for MAPK/NF-κB activation but does not cooperate with TLR2 or TLR6 to induce host resistance to Brucella abortus.
Volume: 99
Issue: 5
Pages: 771-80
Protein
Organism: Mus musculus
Length: 102  
Fragment?: true
Protein
Organism: Mus musculus
Length: 795  
Fragment?: false
Protein
Organism: Mus musculus
Length: 806  
Fragment?: false
Protein
Organism: Mus musculus
Length: 806  
Fragment?: false
Publication
First Author: Jiang Z
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.
Volume: 103
Issue: 29
Pages: 10961-6
Publication
First Author: Takeuchi O
Year: 2001
Journal: Int Immunol
Title: Discrimination of bacterial lipoproteins by Toll-like receptor 6.
Volume: 13
Issue: 7
Pages: 933-40
Publication
First Author: Takeuchi O
Year: 2002
Journal: J Immunol
Title: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.
Volume: 169
Issue: 1
Pages: 10-4
Publication
First Author: Fong DJ
Year: 2010
Journal: Immunology
Title: Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis.
Volume: 130
Issue: 1
Pages: 125-36
Publication
First Author: Kim JH
Year: 2020
Journal: Cancer Prev Res (Phila)
Title: Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.
Volume: 13
Issue: 1
Pages: 25-40
Publication
First Author: Kang JY
Year: 2009
Journal: Immunity
Title: Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
Volume: 31
Issue: 6
Pages: 873-84
Publication
First Author: Ozinsky A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Volume: 97
Issue: 25
Pages: 13766-71
Publication
First Author: Liu S
Year: 2012
Journal: J Immunol
Title: TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.
Volume: 188
Issue: 3
Pages: 1098-107
Publication
First Author: Mattos KA
Year: 2010
Journal: J Leukoc Biol
Title: Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis.
Volume: 87
Issue: 3
Pages: 371-84
Publication
First Author: Drage MG
Year: 2009
Journal: Cell Immunol
Title: TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Volume: 258
Issue: 1
Pages: 29-37
Publication
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
Publication
First Author: Nicolle D
Year: 2004
Journal: Infect Immun
Title: Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice.
Volume: 72
Issue: 12
Pages: 6994-7004
Publication
First Author: de Almeida LA
Year: 2013
Journal: Infect Immun
Title: Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice.
Volume: 81
Issue: 5
Pages: 1654-62
Publication
First Author: Marinho FA
Year: 2013
Journal: Eur J Immunol
Title: Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
Volume: 43
Issue: 9
Pages: 2373-85
Publication
First Author: Ammerdorffer A
Year: 2015
Journal: J Infect Dis
Title: Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.
Volume: 211
Issue: 6
Pages: 978-87
Publication
First Author: Oosting M
Year: 2011
Journal: PLoS One
Title: TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.
Volume: 6
Issue: 10
Pages: e25998
Publication
First Author: Chang S
Year: 2007
Journal: J Leukoc Biol
Title: Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
Volume: 82
Issue: 3
Pages: 479-87
Publication
First Author: Ray A
Year: 2005
Journal: Immunology
Title: Porin of Shigella dysenteriae enhances Toll-like receptors 2 and 6 of mouse peritoneal B-2 cells and induces the expression of immunoglobulin M, immunoglobulin G2a and immunoglobulin A.
Volume: 114
Issue: 1
Pages: 94-100
Publication
First Author: Riccioli A
Year: 2006
Journal: J Immunol
Title: Sertoli cells initiate testicular innate immune responses through TLR activation.
Volume: 177
Issue: 10
Pages: 7122-30
Publication
First Author: Quesniaux VJ
Year: 2004
Journal: J Immunol
Title: Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans.
Volume: 172
Issue: 7
Pages: 4425-34
Publication
First Author: Leng CH
Year: 2010
Journal: Mol Immunol
Title: A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide.
Volume: 47
Issue: 11-12
Pages: 2015-21
Publication
First Author: Henneke P
Year: 2001
Journal: J Immunol
Title: Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Volume: 167
Issue: 12
Pages: 7069-76
Publication
First Author: Owens AP 3rd
Year: 2012
Journal: J Clin Invest
Title: Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin.
Volume: 122
Issue: 2
Pages: 558-68
Publication  
First Author: Hume DA
Year: 2001
Journal: BMC Immunol
Title: Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state.
Volume: 2
Pages: 11
Publication
First Author: Murawski MR
Year: 2009
Journal: J Virol
Title: Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.
Volume: 83
Issue: 3
Pages: 1492-500
Publication
First Author: Abplanalp AL
Year: 2009
Journal: PLoS One
Title: TLR-dependent control of Francisella tularensis infection and host inflammatory responses.
Volume: 4
Issue: 11
Pages: e7920
Publication
First Author: Ray A
Year: 2004
Journal: Mol Immunol
Title: Up-regulation of CD80-CD86 and IgA on mouse peritoneal B-1 cells by porin of Shigella dysenteriae is Toll-like receptors 2 and 6 dependent.
Volume: 41
Issue: 12
Pages: 1167-75
Publication
First Author: Kim S
Year: 2009
Journal: Nature
Title: Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.
Volume: 457
Issue: 7225
Pages: 102-6
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "m2sd3", updated February 2, 2009
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "m2sd2", updated February 2, 2009
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Recored for "m2sd1", updated February 2, 2009
Publication
First Author: Buwitt-Beckmann U
Year: 2005
Journal: Eur J Immunol
Title: Toll-like receptor 6-independent signaling by diacylated lipopeptides.
Volume: 35
Issue: 1
Pages: 282-9
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:5751719
Age: embryonic day 13.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751719
Age: embryonic day 15.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5751719
Age: embryonic day 19.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:5751719
Age: postnatal day 2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751719
Age: postnatal day 5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751719
Age: postnatal day 7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751759
Age: postnatal week 8
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751759
Age: postnatal week 8
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:5751719
Age: embryonic day 11.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Num: 1
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Num: 2
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Num: 3
Publication
First Author: De Luca A
Year: 2012
Journal: J Clin Invest
Title: CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease.
Volume: 122
Issue: 5
Pages: 1816-31
Publication
First Author: DePaolo RW
Year: 2012
Journal: J Exp Med
Title: A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.
Volume: 209
Issue: 8
Pages: 1437-44
Publication
First Author: Grote K
Year: 2010
Journal: Blood
Title: Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration.
Volume: 115
Issue: 12
Pages: 2543-52
Publication
First Author: Sanchez-Lopez JA
Year: 2014
Journal: Biol Reprod
Title: Local activation of uterine Toll-like receptor 2 and 2/6 decreases embryo implantation and affects uterine receptivity in mice.
Volume: 90
Issue: 4
Pages: 87
Publication
First Author: Kurt-Jones EA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis.
Volume: 101
Issue: 5
Pages: 1315-20
Publication
First Author: Pasquevich KA
Year: 2010
Journal: J Immunol
Title: The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
Volume: 184
Issue: 9
Pages: 5200-12
Publication
First Author: Deckwerth TL
Year: 1998
Journal: Exp Neurol
Title: Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.
Volume: 152
Issue: 1
Pages: 150-62
Publication
First Author: Shen KY
Year: 2014
Journal: J Immunol
Title: Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.
Volume: 192
Issue: 9
Pages: 4233-41
Publication
First Author: Buwitt-Beckmann U
Year: 2006
Journal: J Biol Chem
Title: TLR1- and TLR6-independent recognition of bacterial lipopeptides.
Volume: 281
Issue: 14
Pages: 9049-57
Publication
First Author: Jimenez-Dalmaroni MJ
Year: 2009
Journal: PLoS One
Title: Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
Volume: 4
Issue: 10
Pages: e7411
Publication
First Author: Katz J
Year: 2006
Journal: Infect Immun
Title: Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.
Volume: 74
Issue: 5
Pages: 2809-16
Publication
First Author: Zeisel MB
Year: 2005
Journal: J Immunol
Title: Cross talk between MyD88 and focal adhesion kinase pathways.
Volume: 174
Issue: 11
Pages: 7393-7
Publication
First Author: Marta M
Year: 2008
Journal: Eur J Immunol
Title: Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis.
Volume: 38
Issue: 2
Pages: 565-75
Publication
First Author: Yang D
Year: 2008
Journal: J Exp Med
Title: Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
Volume: 205
Issue: 1
Pages: 79-90
Publication
First Author: Turner JD
Year: 2009
Journal: J Biol Chem
Title: Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
Volume: 284
Issue: 33
Pages: 22364-78
Publication  
First Author: Monlish DA
Year: 2020
Journal: Exp Hematol
Title: TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.
Volume: 88
Pages: 42-55