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Search results 1 to 100 out of 300 for Tlr6

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Toll-like receptor 6 (TLR6) participates in the innate immune response to Gram-positive bacteria and fungi. TLRs recognize specific molecular patterns present only in micro-organisms. TLR1 and TLR6 are involved in the discrimination of a subtle difference between triacyl and diacyl lipopeptides through interaction with TLR2 []. Cooperatively with TLR2, TLR6 recognises mycoplasmal macrophage-activating lipopeptide-2 (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) []. TLR6 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [].
Publication
First Author: Takeuchi O
Year: 1999
Journal: Gene
Title: TLR6: A novel member of an expanding toll-like receptor family.
Volume: 231
Issue: 1-2
Pages: 59-65
Protein
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
Publication
First Author: Sugawara I
Year: 2003
Journal: Microbiol Immunol
Title: Mycobacterial infection in TLR2 and TLR6 knockout mice.
Volume: 47
Issue: 5
Pages: 327-36
Publication
First Author: Curtiss LK
Year: 2012
Journal: J Lipid Res
Title: Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.
Volume: 53
Issue: 10
Pages: 2126-32
Publication
First Author: Chen J
Year: 2015
Journal: PLoS Pathog
Title: Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection.
Volume: 11
Issue: 7
Pages: e1005053
Publication
First Author: Moreira AP
Year: 2011
Journal: J Clin Invest
Title: The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.
Volume: 121
Issue: 11
Pages: 4420-32
Publication
First Author: Bulut Y
Year: 2001
Journal: J Immunol
Title: Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
Volume: 167
Issue: 2
Pages: 987-94
Publication
First Author: Miranda-Hernandez S
Year: 2011
Journal: J Immunol
Title: Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Volume: 187
Issue: 2
Pages: 791-804
Publication
First Author: Takeda K
Year: 2002
Journal: J Endotoxin Res
Title: Recognition of lipopeptides by Toll-like receptors.
Volume: 8
Issue: 6
Pages: 459-63
Publication
First Author: Gomes MT
Year: 2016
Journal: J Leukoc Biol
Title: TLR9 is required for MAPK/NF-κB activation but does not cooperate with TLR2 or TLR6 to induce host resistance to Brucella abortus.
Volume: 99
Issue: 5
Pages: 771-80
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
Publication
First Author: Jiang Z
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.
Volume: 103
Issue: 29
Pages: 10961-6
Publication
First Author: Takeuchi O
Year: 2001
Journal: Int Immunol
Title: Discrimination of bacterial lipoproteins by Toll-like receptor 6.
Volume: 13
Issue: 7
Pages: 933-40
Publication
First Author: Takeuchi O
Year: 2002
Journal: J Immunol
Title: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.
Volume: 169
Issue: 1
Pages: 10-4
Publication
First Author: Fong DJ
Year: 2010
Journal: Immunology
Title: Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis.
Volume: 130
Issue: 1
Pages: 125-36
Publication
First Author: Kim JH
Year: 2020
Journal: Cancer Prev Res (Phila)
Title: Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.
Volume: 13
Issue: 1
Pages: 25-40
Publication
First Author: Kang JY
Year: 2009
Journal: Immunity
Title: Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
Volume: 31
Issue: 6
Pages: 873-84
Publication
First Author: Ozinsky A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Volume: 97
Issue: 25
Pages: 13766-71
Publication
First Author: Liu S
Year: 2012
Journal: J Immunol
Title: TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.
Volume: 188
Issue: 3
Pages: 1098-107
Publication
First Author: Mattos KA
Year: 2010
Journal: J Leukoc Biol
Title: Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis.
Volume: 87
Issue: 3
Pages: 371-84
Publication
First Author: Drage MG
Year: 2009
Journal: Cell Immunol
Title: TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Volume: 258
Issue: 1
Pages: 29-37
Publication
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
Publication
First Author: de Almeida LA
Year: 2013
Journal: Infect Immun
Title: Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice.
Volume: 81
Issue: 5
Pages: 1654-62
Publication
First Author: Marinho FA
Year: 2013
Journal: Eur J Immunol
Title: Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
Volume: 43
Issue: 9
Pages: 2373-85
Publication
First Author: Ammerdorffer A
Year: 2015
Journal: J Infect Dis
Title: Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.
Volume: 211
Issue: 6
Pages: 978-87
Publication
First Author: Chang S
Year: 2007
Journal: J Leukoc Biol
Title: Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
Volume: 82
Issue: 3
Pages: 479-87
Publication
First Author: Nicolle D
Year: 2004
Journal: Infect Immun
Title: Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice.
Volume: 72
Issue: 12
Pages: 6994-7004
Publication
First Author: Oosting M
Year: 2011
Journal: PLoS One
Title: TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.
Volume: 6
Issue: 10
Pages: e25998
Publication
First Author: Ray A
Year: 2005
Journal: Immunology
Title: Porin of Shigella dysenteriae enhances Toll-like receptors 2 and 6 of mouse peritoneal B-2 cells and induces the expression of immunoglobulin M, immunoglobulin G2a and immunoglobulin A.
Volume: 114
Issue: 1
Pages: 94-100
Publication
First Author: Riccioli A
Year: 2006
Journal: J Immunol
Title: Sertoli cells initiate testicular innate immune responses through TLR activation.
Volume: 177
Issue: 10
Pages: 7122-30
Publication
First Author: Owens AP 3rd
Year: 2012
Journal: J Clin Invest
Title: Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin.
Volume: 122
Issue: 2
Pages: 558-68
Publication
First Author: Henneke P
Year: 2001
Journal: J Immunol
Title: Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Volume: 167
Issue: 12
Pages: 7069-76
Publication
First Author: Quesniaux VJ
Year: 2004
Journal: J Immunol
Title: Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans.
Volume: 172
Issue: 7
Pages: 4425-34
Publication
First Author: Leng CH
Year: 2010
Journal: Mol Immunol
Title: A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide.
Volume: 47
Issue: 11-12
Pages: 2015-21
Publication  
First Author: Hume DA
Year: 2001
Journal: BMC Immunol
Title: Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state.
Volume: 2
Pages: 11
Publication
First Author: Ray A
Year: 2004
Journal: Mol Immunol
Title: Up-regulation of CD80-CD86 and IgA on mouse peritoneal B-1 cells by porin of Shigella dysenteriae is Toll-like receptors 2 and 6 dependent.
Volume: 41
Issue: 12
Pages: 1167-75
Publication
First Author: Biswas S
Year: 2017
Journal: Circ Res
Title: TLR2 Plays a Key Role in Platelet Hyperreactivity and Accelerated Thrombosis Associated With Hyperlipidemia.
Volume: 121
Issue: 8
Pages: 951-962
Publication
First Author: Kim S
Year: 2009
Journal: Nature
Title: Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.
Volume: 457
Issue: 7225
Pages: 102-6
Publication
First Author: Abplanalp AL
Year: 2009
Journal: PLoS One
Title: TLR-dependent control of Francisella tularensis infection and host inflammatory responses.
Volume: 4
Issue: 11
Pages: e7920
Publication
First Author: Murawski MR
Year: 2009
Journal: J Virol
Title: Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.
Volume: 83
Issue: 3
Pages: 1492-500
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "m2sd2", updated February 2, 2009
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Recored for "m2sd1", updated February 2, 2009
Publication      
First Author: Siggs OM
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "m2sd3", updated February 2, 2009
Publication
First Author: Buwitt-Beckmann U
Year: 2005
Journal: Eur J Immunol
Title: Toll-like receptor 6-independent signaling by diacylated lipopeptides.
Volume: 35
Issue: 1
Pages: 282-9
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Label: Dnmt3b-/-
Specimen Num: 1
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Label: Dnmt3a-/-
Specimen Num: 2
GXD Expression      
Probe: MGI:5751172
Assay Type: RT-PCR
Annotation Date: 2016-03-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5751181
Age: embryonic day 9.5
Image: 5
Specimen Label: WT
Specimen Num: 3
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:5751719
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:5751719
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751719
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5751719
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:5751719
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751719
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751719
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751759
Age: postnatal week 8
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751587
Assay Type: RT-PCR
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5751759
Age: postnatal week 8
Specimen Label: TLR2KO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Specimen Label: TLR2+/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Specimen Label: TLR2-/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Specimen Label: TLR2+/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751601
Assay Type: Western blot
Annotation Date: 2016-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5751774
Age: embryonic day 15.0
Specimen Label: TLR2-/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7334823
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:7334823
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7334823
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7334823
Age: embryonic day 16.0
Image: 1
Specimen Label: E16
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7334823
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334823
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334823
Age: embryonic day 19.0
Image: 1
Specimen Label: E19
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7334823
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334823
Age: postnatal day 4
Image: 1
Specimen Label: P4
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334823
Age: postnatal day 8
Image: 1
Specimen Label: P8
Detected: true
Specimen Num: 10