|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 913 for Tlr7

<< First    < Previous  |  Next >    Last >>
0.036s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
51284 | TLR7
Type: gene
Organism: human
•
•
•
•
•
Gene
100151703 | tlr7
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
317468 | Tlr7
Type: gene
Organism: rat
•
•
•
•
•
Gene
491743 | TLR7
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
473521 | TLR7
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
493686 | TLR7
Type: gene
Organism: cattle
•
•
•
•
•
Gene
418638 | TLR7
Type: gene
Organism: chicken
•
•
•
•
•
Gene
100534776 | tlr7
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
574291 | TLR7
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Domain
IPR026880 | TLR7
Type: Family
Description: Toll-like receptor 7 (TLR7) is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR, which is activated by single-stranded RNA, acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [, ].
•
•
•
•
•
Protein Coding Gene
MGI:2176882 | Tlr7
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
18250417 | J:131922
First Author: Gantier MP
Year: 2008
Journal: J Immunol
Title: TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages.
Volume: 180
Issue: 4
Pages: 2117-24
•
•
•
•
•
Publication
14976261 | J:90024
First Author: Diebold SS
Year: 2004
Journal: Science
Title: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.
Volume: 303
Issue: 5663
Pages: 1529-31
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5609311
Assay Type: RT-PCR
Annotation Date: 2015-01-09
Strength: Present
Sex: Female
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5609326
Age: embryonic day 17.5
Image: 2
Specimen Label: TLR7 KO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5609311
Assay Type: RT-PCR
Annotation Date: 2015-01-09
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:5609329
Age: embryonic day 17.5
Image: 2
Specimen Label: TLR7 KO
Specimen Num: 2
•
•
•
•
•
Publication
31546246 | J:287430
First Author: Majer O
Year: 2019
Journal: Nature
Title: UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
Volume: 575
Issue: 7782
Pages: 366-370
•
•
•
•
•
Publication
23382559 | J:193610
First Author: Sun X
Year: 2013
Journal: J Immunol
Title: Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
Volume: 190
Issue: 6
Pages: 2536-43
•
•
•
•
•
Publication
31642126 | J:298049
First Author: Javmen A
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Targeting the TLR7 signalosome assembly.
Volume: 108
Issue: 6
Pages: 1697-1706
•
•
•
•
•
Protein
Q599W9
Organism: Mus musculus/domesticus
Length: 10  
Fragment?: true
•
•
•
•
•
Publication
35477763 | J:324448
First Author: Brown GJ
Year: 2022
Journal: Nature
Title: TLR7 gain-of-function genetic variation causes human lupus.
Volume: 605
Issue: 7909
Pages: 349-356
•
•
•
•
•
Protein
Q3T997
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: true
•
•
•
•
•
Protein
P58681
Organism: Mus musculus/domesticus
Length: 1050  
Fragment?: false
•
•
•
•
•
Protein
U5LLB3
Organism: Mus musculus/domesticus
Length: 1049  
Fragment?: true
•
•
•
•
•
Protein
U5LLA9
Organism: Mus musculus/domesticus
Length: 1049  
Fragment?: true
•
•
•
•
•
Protein
U5LI18
Organism: Mus musculus/domesticus
Length: 1049  
Fragment?: true
•
•
•
•
•
Protein
Q548J0
Organism: Mus musculus/domesticus
Length: 1050  
Fragment?: false
•
•
•
•
•
Publication
37795093 | J:347835
 
First Author: Miles MA
Year: 2023
Journal: Front Immunol
Title: TLR7 promotes chronic airway disease in RSV-infected mice.
Volume: 14
Pages: 1240552
•
•
•
•
•
Publication
24145511 | J:207730
First Author: Giltiay NV
Year: 2013
Journal: J Exp Med
Title: Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
Volume: 210
Issue: 12
Pages: 2773-89
•
•
•
•
•
Publication
25794167 | J:229194
First Author: Boneparth A
Year: 2015
Journal: PLoS One
Title: TLR7 influences germinal center selection in murine SLE.
Volume: 10
Issue: 3
Pages: e0119925
•
•
•
•
•
Publication
34108972 | J:312592
 
First Author: Wang Y
Year: 2021
Journal: Front Immunol
Title: TLR7 Signaling Drives the Development of Sjögren's Syndrome.
Volume: 12
Pages: 676010
•
•
•
•
•
Publication
25648980 | J:221365
 
First Author: Kanno A
Year: 2015
Journal: Nat Commun
Title: Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.
Volume: 6
Pages: 6119
•
•
•
•
•
Publication
21801870 | J:174600
First Author: Butchi NB
Year: 2011
Journal: Am J Pathol
Title: TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS.
Volume: 179
Issue: 2
Pages: 783-94
•
•
•
•
•
Publication
22916010 | J:195368
First Author: Maschalidi S
Year: 2012
Journal: PLoS Pathog
Title: Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.
Volume: 8
Issue: 8
Pages: e1002841
•
•
•
•
•
Publication
22615569 | J:195383
First Author: Karnam G
Year: 2012
Journal: PLoS Pathog
Title: CD200 receptor controls sex-specific TLR7 responses to viral infection.
Volume: 8
Issue: 5
Pages: e1002710
•
•
•
•
•
Publication
37606042 | J:342540
 
First Author: Cosgrove HA
Year: 2023
Journal: JCI Insight
Title: B cell-intrinsic TLR7 expression drives severe lupus in TLR9-deficient mice.
Volume: 8
Issue: 16
•
•
•
•
•
Publication
26567289 | J:249473
First Author: Celhar T
Year: 2016
Journal: Int Immunol
Title: TLR7 and TLR9 ligands regulate antigen presentation by macrophages.
Volume: 28
Issue: 5
Pages: 223-32
•
•
•
•
•
Publication
23843519 | J:199815
First Author: Liu HY
Year: 2013
Journal: J Neurosci
Title: TLR7 negatively regulates dendrite outgrowth through the Myd88-c-Fos-IL-6 pathway.
Volume: 33
Issue: 28
Pages: 11479-93
•
•
•
•
•
Publication
18490763 | J:136380
First Author: Butchi NB
Year: 2008
Journal: J Immunol
Title: Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.
Volume: 180
Issue: 11
Pages: 7604-12
•
•
•
•
•
Publication
24018482 | J:208210
First Author: Lalive PH
Year: 2014
Journal: Eur J Immunol
Title: TLR7 signaling exacerbates CNS autoimmunity through downregulation of Foxp3+ Treg cells.
Volume: 44
Issue: 1
Pages: 46-57
•
•
•
•
•
Publication
35126381 | J:337165
 
First Author: Chang X
Year: 2021
Journal: Front Immunol
Title: TLR7 Signaling Shapes and Maintains Antibody Diversity Upon Virus-Like Particle Immunization.
Volume: 12
Pages: 827256
•
•
•
•
•
Publication
17371961 | J:145062
First Author: Berghöfer B
Year: 2007
Journal: J Immunol
Title: Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha production.
Volume: 178
Issue: 7
Pages: 4072-9
•
•
•
•
•
Publication
16709748 | J:109758
First Author: Pisitkun P
Year: 2006
Journal: Science
Title: Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.
Volume: 312
Issue: 5780
Pages: 1669-72
•
•
•
•
•
Publication
32521271 | J:301712
First Author: Regli IB
Year: 2020
Journal: Cell Rep
Title: TLR7 Sensing by Neutrophils Is Critical for the Control of Cutaneous Leishmaniasis.
Volume: 31
Issue: 10
Pages: 107746
•
•
•
•
•
Publication
30630901 | J:295155
 
First Author: Akilesh HM
Year: 2019
Journal: Science
Title: Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.
Volume: 363
Issue: 6423
•
•
•
•
•
Publication
34530852 | J:314199
First Author: Proskocil BJ
Year: 2021
Journal: J Neuroinflammation
Title: TLR7 is expressed by support cells, but not sensory neurons, in ganglia.
Volume: 18
Issue: 1
Pages: 209
•
•
•
•
•
Publication
27622045 | J:264952
First Author: Wiedemann GM
Year: 2016
Journal: Oncoimmunology
Title: A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice.
Volume: 5
Issue: 7
Pages: e1189051
•
•
•
•
•
Publication
32849556 | J:308206
 
First Author: Chodisetti SB
Year: 2020
Journal: Front Immunol
Title: TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner.
Volume: 11
Pages: 1632
•
•
•
•
•
Publication
25074614 | J:215986
First Author: Chatterjee S
Year: 2014
Journal: Cancer Res
Title: TLR7 promotes tumor progression, chemotherapy resistance, and poor clinical outcomes in non-small cell lung cancer.
Volume: 74
Issue: 18
Pages: 5008-18
•
•
•
•
•
Publication
34473195 | J:317308
 
First Author: Rappe JCF
Year: 2021
Journal: J Exp Med
Title: A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza.
Volume: 218
Issue: 11
•
•
•
•
•
Publication
23303674 | J:193249
First Author: Buechler MB
Year: 2013
Journal: J Immunol
Title: Cutting edge: Type I IFN drives emergency myelopoiesis and peripheral myeloid expansion during chronic TLR7 signaling.
Volume: 190
Issue: 3
Pages: 886-91
•
•
•
•
•
Publication
24698267 | J:213160
First Author: Park CK
Year: 2014
Journal: Neuron
Title: Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
Volume: 82
Issue: 1
Pages: 47-54
•
•
•
•
•
Publication
27600904 | J:246481
First Author: Desnues B
Year: 2016
Journal: Eur J Immunol
Title: The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.
Volume: 46
Issue: 12
Pages: 2801-2811
•
•
•
•
•
Publication
20624950 | J:162380
First Author: Lukacs NW
Year: 2010
Journal: J Immunol
Title: Respiratory virus-induced TLR7 activation controls IL-17-associated increased mucus via IL-23 regulation.
Volume: 185
Issue: 4
Pages: 2231-9
•
•
•
•
•
Publication
34381063 | J:359915
First Author: Lee J
Year: 2021
Journal: Sci Rep
Title: Overexpression of cathepsin S exacerbates lupus pathogenesis through upregulation TLR7 and IFN-α in transgenic mice.
Volume: 11
Issue: 1
Pages: 16348
•
•
•
•
•
Publication
37566453 | J:354783
   
First Author: Jackson WD
Year: 2023
Journal: Elife
Title: TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity.
Volume: 12
•
•
•
•
•
Publication
26154133 | J:245564
First Author: Yelamanchili SV
Year: 2015
Journal: PLoS Pathog
Title: MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease.
Volume: 11
Issue: 7
Pages: e1005032
•
•
•
•
•
Publication
25763771 | J:229712
First Author: Khan AR
Year: 2015
Journal: Eur J Immunol
Title: Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.
Volume: 45
Issue: 6
Pages: 1842-54
•
•
•
•
•
Publication
23029281 | J:191976
First Author: Hayashi T
Year: 2012
Journal: PLoS One
Title: Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system.
Volume: 7
Issue: 9
Pages: e45860
•
•
•
•
•
Publication
21131420 | J:168697
First Author: Grela F
Year: 2011
Journal: J Immunol
Title: The TLR7 agonist R848 alleviates allergic inflammation by targeting invariant NKT cells to produce IFN-gamma.
Volume: 186
Issue: 1
Pages: 284-90
•
•
•
•
•
Publication
34313894 | J:341307
First Author: Wu N
Year: 2021
Journal: Mol Cell Biochem
Title: Sequence-specific extracellular microRNAs activate TLR7 and induce cytokine secretion and leukocyte migration.
Volume: 476
Issue: 11
Pages: 4139-4151
•
•
•
•
•
Publication
31930147 | J:292422
 
First Author: Qu J
Year: 2019
Journal: J Immunol Res
Title: TLR7 Modulated T Cell Response in the Mesenteric Lymph Node of Schistosoma japonicum-Infected C57BL/6 Mice.
Volume: 2019
Pages: 2691808
•
•
•
•
•
Publication
28843858 | J:251169
First Author: Liao YR
Year: 2017
Journal: Biochem Biophys Res Commun
Title: TLR7 deficiency contributes to attenuated diabetic retinopathy via inhibition of inflammatory response.
Volume: 493
Issue: 2
Pages: 1136-1142
•
•
•
•
•
Publication
21383246 | J:170458
First Author: Iavarone C
Year: 2011
Journal: J Immunol
Title: A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding.
Volume: 186
Issue: 7
Pages: 4213-22
•
•
•
•
•
Publication
24909816 | J:215509
 
First Author: Nazmi A
Year: 2014
Journal: Neurobiol Dis
Title: TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection.
Volume: 69
Pages: 235-47
•
•
•
•
•
Publication
27003259 | J:234870
First Author: Nyberg WA
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Imiquimod induces ER stress and Ca(2+) influx independently of TLR7 and TLR8.
Volume: 473
Issue: 4
Pages: 789-794
•
•
•
•
•
Publication
31998321 | J:297922
 
First Author: Wirth JR
Year: 2019
Journal: Front Immunol
Title: TLR7 Agonism Accelerates Disease and Causes a Fatal Myeloproliferative Disorder in NZM 2410 Lupus Mice.
Volume: 10
Pages: 3054
•
•
•
•
•
Publication
30930901 | J:284385
 
First Author: Solmaz G
Year: 2019
Journal: Front Immunol
Title: TLR7 Controls VSV Replication in CD169+ SCS Macrophages and Associated Viral Neuroinvasion.
Volume: 10
Pages: 466
•
•
•
•
•
Publication
28652396 | J:251506
First Author: Ye J
Year: 2017
Journal: J Immunol
Title: TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy.
Volume: 199
Issue: 3
Pages: 941-954
•
•
•
•
•
Publication
18581336 | J:137453
First Author: Anders HJ
Year: 2008
Journal: Eur J Immunol
Title: Molecular mimicry in innate immunity? The viral RNA recognition receptor TLR7 accelerates murine lupus.
Volume: 38
Issue: 7
Pages: 1795-9
•
•
•
•
•
Publication
23918369 | J:200675
First Author: Pang IK
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I.
Volume: 110
Issue: 34
Pages: 13910-5
•
•
•
•
•
Publication
31552019 | J:283144
 
First Author: Hanna Kazazian N
Year: 2019
Journal: Front Immunol
Title: Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling.
Volume: 10
Pages: 2015
•
•
•
•
•
Publication
33443222 | J:300027
 
First Author: Wang Q
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
Volume: 118
Issue: 1
•
•
•
•
•
Publication
29150602 | J:256313
First Author: Saitoh SI
Year: 2017
Journal: Nat Commun
Title: TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells.
Volume: 8
Issue: 1
Pages: 1592
•
•
•
•
•
Publication
27405980 | J:260301
First Author: Liu B
Year: 2016
Journal: Sci Signal
Title: Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways.
Volume: 9
Issue: 436
Pages: ra70
•
•
•
•
•
Publication
25239130 | J:337115
First Author: Li X
Year: 2015
Journal: Int Immunol
Title: Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.
Volume: 27
Issue: 2
Pages: 83-94
•
•
•
•
•
Publication
21765012 | J:179158
First Author: Fishelevich R
Year: 2011
Journal: J Immunol
Title: Imiquimod-induced TLR7 signaling enhances repair of DNA damage induced by ultraviolet light in bone marrow-derived cells.
Volume: 187
Issue: 4
Pages: 1664-73
•
•
•
•
•
Publication
16105838 | J:102910
First Author: Nishiya T
Year: 2005
Journal: J Biol Chem
Title: TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements.
Volume: 280
Issue: 44
Pages: 37107-17
•
•
•
•
•
Publication
21966467 | J:177864
First Author: Jeisy-Scott V
Year: 2011
Journal: PLoS One
Title: Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice.
Volume: 6
Issue: 9
Pages: e25242
•
•
•
•
•
Publication
21813451 | J:177064
First Author: Oh JZ
Year: 2011
Journal: Blood
Title: TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway.
Volume: 118
Issue: 11
Pages: 3028-38
•
•
•
•
•
Publication
19587008 | J:151708
First Author: Green NM
Year: 2009
Journal: J Immunol
Title: Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop.
Volume: 183
Issue: 3
Pages: 1569-76
•
•
•
•
•
Publication
23761632 | J:204821
First Author: Clingan JM
Year: 2013
Journal: J Immunol
Title: B Cell-intrinsic TLR7 signaling is required for optimal B cell responses during chronic viral infection.
Volume: 191
Issue: 2
Pages: 810-8
•
•
•
•
•
Publication
18424698 | J:134322
First Author: Zucchini N
Year: 2008
Journal: J Immunol
Title: Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection.
Volume: 180
Issue: 9
Pages: 5799-803
•
•
•
•
•
Publication
18824599 | J:144246
First Author: Baenziger S
Year: 2009
Journal: Blood
Title: Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology.
Volume: 113
Issue: 2
Pages: 377-88
•
•
•
•
•
Publication
12032557 | J:114769
First Author: Jurk M
Year: 2002
Journal: Nat Immunol
Title: Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848.
Volume: 3
Issue: 6
Pages: 499
•
•
•
•
•
Publication
18606711 | J:137656
First Author: Santiago-Raber ML
Year: 2008
Journal: J Immunol
Title: Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.
Volume: 181
Issue: 2
Pages: 1556-62
•
•
•
•
•
Publication
37180169 | J:346115
 
First Author: Li J
Year: 2023
Journal: Front Immunol
Title: TLR7 modulates extramedullary splenic erythropoiesis in P. yoelii NSM-infected mice through the regulation of iron metabolism of macrophages with IFN-γ.
Volume: 14
Pages: 1123074
•
•
•
•
•
Publication
26474053 | J:243980
First Author: Zacca ER
Year: 2015
Journal: PLoS One
Title: Aging Impairs the Ability of Conventional Dendritic Cells to Cross-Prime CD8+ T Cells upon Stimulation with a TLR7 Ligand.
Volume: 10
Issue: 10
Pages: e0140672
•
•
•
•
•
Publication
24376264 | J:207307
First Author: Lebel MÈ
Year: 2014
Journal: J Immunol
Title: Nanoparticle adjuvant sensing by TLR7 enhances CD8+ T cell-mediated protection from Listeria monocytogenes infection.
Volume: 192
Issue: 3
Pages: 1071-8
•
•
•
•
•
Publication
25252960 | J:329665
First Author: Soni C
Year: 2014
Journal: J Immunol
Title: B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.
Volume: 193
Issue: 9
Pages: 4400-14
•
•
•
•
•
Publication
34211367 | J:312766
 
First Author: Dieu RS
Year: 2021
Journal: Front Neurosci
Title: Central Nervous System-Endogenous TLR7 and TLR9 Induce Different Immune Responses and Effects on Experimental Autoimmune Encephalomyelitis.
Volume: 15
Pages: 685645
•
•
•
•
•
Publication
31354711 | J:281852
 
First Author: Celhar T
Year: 2019
Journal: Front Immunol
Title: TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner.
Volume: 10
Pages: 1546
•
•
•
•
•
Publication
22777843 | J:188005
First Author: Biondo C
Year: 2012
Journal: Eur J Immunol
Title: Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis.
Volume: 42
Issue: 10
Pages: 2632-43
•
•
•
•
•
Publication
11812998 | J:90979
First Author: Hemmi H
Year: 2002
Journal: Nat Immunol
Title: Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.
Volume: 3
Issue: 2
Pages: 196-200
•
•
•
•
•
Publication
19430477 | J:149541
First Author: Mancuso G
Year: 2009
Journal: Nat Immunol
Title: Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells.
Volume: 10
Issue: 6
Pages: 587-94
•
•
•
•
•
Publication
39289468 | J:354283
First Author: Wang C
Year: 2024
Journal: Commun Biol
Title: Deficiency of Tlr7 and Irf7 in mice increases the severity of COVID-19 through the reduced interferon production.
Volume: 7
Issue: 1
Pages: 1162
•
•
•
•
•
Publication
- | J:128404
     
First Author: Beutler B
Year: 2007
Journal: MGI Direct Data Submission
Title: An ENU-induced point mutation of Tlr7 specifically ablates immune response to resiquimod
•
•
•
•
•
Publication
30867286 | J:273874
First Author: Wang Y
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Injured liver-released miRNA-122 elicits acute pulmonary inflammation via activating alveolar macrophage TLR7 signaling pathway.
Volume: 116
Issue: 13
Pages: 6162-6171
•
•
•
•
•
Publication
18340381 | J:135976
First Author: Thibault DL
Year: 2008
Journal: J Clin Invest
Title: IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice.
Volume: 118
Issue: 4
Pages: 1417-26
•
•
•
•
•
Publication
22636319 | J:189565
First Author: Sinha S
Year: 2012
Journal: J Leukoc Biol
Title: IFN type I and type II independent enhancement of B cell TLR7 expression by natural killer cells.
Volume: 92
Issue: 4
Pages: 713-22
•
•
•
•
•
Publication
21115693 | J:176864
First Author: Guiducci C
Year: 2010
Journal: J Exp Med
Title: Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.
Volume: 207
Issue: 13
Pages: 2931-42
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom