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Search results 1 to 85 out of 85 for Tm6sf2

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Hits by Strain

Type Details Score
Gene
53345 | TM6SF2
Type: gene
Organism: human
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Gene
100158592 | tm6sf2
Type: gene
Organism: frog, western clawed
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Gene
689029 | Tm6sf2
Type: gene
Organism: rat
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Gene
609715 | TM6SF2
Type: gene
Organism: dog, domestic
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Gene
736763 | TM6SF2
Type: gene
Organism: chimpanzee
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Gene
515889 | TM6SF2
Type: gene
Organism: cattle
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Gene
425719 | TM6SF2
Type: gene
Organism: chicken
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Gene
719756 | TM6SF2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1933210 | Tm6sf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36139452 | J:332459
 
First Author: Zhu W
Year: 2022
Journal: Cells
Title: Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis.
Volume: 11
Issue: 18
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Publication
33638902 | J:322313
First Author: Newberry EP
Year: 2021
Journal: Hepatology
Title: Liver-Specific Deletion of Mouse Tm6sf2 Promotes Steatosis, Fibrosis, and Hepatocellular Cancer.
Volume: 74
Issue: 3
Pages: 1203-1219
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Publication
34746691 | J:314590
First Author: Fan Y
Year: 2021
Journal: iScience
Title: Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2.
Volume: 24
Issue: 11
Pages: 103196
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Publication
11124529 | J:66727
First Author: Carim-Todd L
Year: 2000
Journal: Cytogenet Cell Genet
Title: Cloning of the novel gene TM6SF1 reveals conservation of clusters of paralogous genes between human chromosomes 15q24-->q26 and 19p13.3-->p12.
Volume: 90
Issue: 3-4
Pages: 255-60
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Publication
27013658 | J:234195
First Author: Smagris E
Year: 2016
Journal: J Biol Chem
Title: Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.
Volume: 291
Issue: 20
Pages: 10659-76
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Publication
26774178 | J:235704
First Author: Fan Y
Year: 2016
Journal: Gastroenterology
Title: Hepatic Transmembrane 6 Superfamily Member 2 Regulates Cholesterol Metabolism in Mice.
Volume: 150
Issue: 5
Pages: 1208-1218
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Publication
32776921 | J:296036
First Author: Li BT
Year: 2020
Journal: PLoS Genet
Title: Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease.
Volume: 16
Issue: 8
Pages: e1008955
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Protein Coding Gene
MGP_CAROLIEiJ_G0031127 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1933210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021592 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032245 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3667028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692320
Age: postnatal adult
Image: MRC Harwell_1612458
Specimen Label: MRC Harwell_1612458
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692320
Age: postnatal adult
Image: MRC Harwell_1612457
Specimen Label: MRC Harwell_1612457
Detected: true
Specimen Num: 1
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Publication
- | J:90559
     
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
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Publication
- | J:72400
       
First Author: Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Mouse Genome Sequence Project Annotation
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Tm6sf2<em1Yech> | MGI:5896993
Name: transmembrane 6 superfamily member 2; endonuclease-mediated mutation 1, Y Eugene Chen
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
34923175 | J:320935
First Author: Luo F
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats.
Volume: 13
Issue: 3
Pages: 879-899
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Allele
Tm6sf2<em1Smoc> | MGI:7292827
Name: transmembrane 6 superfamily member 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Strain
MGI:6429675 | C57BL/6JSmoc-Tm6sf2<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
25566323 | -
 
First Author: Sanchez-Pulido L
Year: 2014
Journal: Front Genet
Title: TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease.
Volume: 5
Pages: 439
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Publication
24531328 | -
First Author: Kozlitina J
Year: 2014
Journal: Nat Genet
Title: Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease.
Volume: 46
Issue: 4
Pages: 352-6
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Publication
24633158 | -
First Author: Holmen OL
Year: 2014
Journal: Nat Genet
Title: Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.
Volume: 46
Issue: 4
Pages: 345-51
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Protein
P58749
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
Q8R1J1
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
A0A0R4J0J9
Organism: Mus musculus/domesticus
Length: 376  
Fragment?: false
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Protein
Q3TA24
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
D3YX52
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Protein
E9QM19
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
Q3TA39
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein Domain
IPR033118 | EXPERA
Type: Domain
Description: The EXPERA (EXPanded EBP superfamilly) domain is conserved among the followingprotein families:Vertebrate TM6SF1 (Transmembrane 6 Superfamily Member 1).Vertebrate TM6SF2 (Transmembrane 6 Superfamily Member 2).Eukaryotic MAC30 (Meningioma-associated protein 30) also known as TMEM97(Transmembrane protein 97), mainly localized in the endoplasmic reticulum(ER).Eukaryotic EBP (Emopamil binding protein), an enzyme with a D8, D7 sterolisomerase activity that catalyzes the transposition of a double bond fromC8=C9 to C7=C8 in the sterol B-ring.The EXPERA domain contains four transmembrane regions and is likely to possessa sterol isomerase catalytic activity [].
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Protein
Q8VD00
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
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Protein
P70245
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
Q9D0P0
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: false
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Protein
A2AC29
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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