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Search results 1 to 100 out of 105 for Tmc2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kurima K
Year: 2015
Journal: Cell Rep
Title: TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.
Volume: 12
Issue: 10
Pages: 1606-17
Publication
First Author: Asai Y
Year: 2018
Journal: Sci Rep
Title: Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1.
Volume: 8
Issue: 1
Pages: 12124
Publication
First Author: Pan B
Year: 2013
Journal: Neuron
Title: TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear.
Volume: 79
Issue: 3
Pages: 504-15
Publication
First Author: Nakanishi H
Year: 2018
Journal: Sci Rep
Title: Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function.
Volume: 8
Issue: 1
Pages: 12125
Publication
First Author: Giese APJ
Year: 2017
Journal: Nat Commun
Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Volume: 8
Issue: 1
Pages: 43
Publication
First Author: Kurima K
Year: 2002
Journal: Nat Genet
Title: Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function.
Volume: 30
Issue: 3
Pages: 277-84
Publication
First Author: Askew C
Year: 2015
Journal: Sci Transl Med
Title: Tmc gene therapy restores auditory function in deaf mice.
Volume: 7
Issue: 295
Pages: 295ra108
Publication
First Author: Maeda R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2.
Volume: 111
Issue: 35
Pages: 12907-12
Publication
First Author: Beurg M
Year: 2014
Journal: J Gen Physiol
Title: Conductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutants.
Volume: 144
Issue: 1
Pages: 55-69
Publication
First Author: Kawashima Y
Year: 2011
Journal: J Clin Invest
Title: Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
Volume: 121
Issue: 12
Pages: 4796-809
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5474607
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474610
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5474607
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474610
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5474606
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474609
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5474606
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474609
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5474605
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474608
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5474605
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:5474608
Age: postnatal day 3
Image: S2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Stage: TS28
Assay Id: MGI:5474487
Age: postnatal day 21
Image: 1
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Stage: TS28
Assay Id: MGI:5474487
Age: postnatal day 7
Image: 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Stage: TS27
Assay Id: MGI:5474487
Age: postnatal day 3
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Stage: TS27
Assay Id: MGI:5474487
Age: postnatal day 1
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729326
Stage: TS26
Assay Id: MGI:5474487
Age: embryonic day 18.0
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729325
Stage: TS25
Assay Id: MGI:5474487
Age: embryonic day 17.0
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729324
Stage: TS24
Assay Id: MGI:5474487
Age: embryonic day 16.0
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729323
Stage: TS23
Assay Id: MGI:5474487
Age: embryonic day 15.0
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474579
Age: postnatal day 8
Image: S1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474579
Age: postnatal day 6
Image: S1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474579
Age: postnatal day 4
Image: S1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474579
Age: postnatal day 2
Image: S1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474579
Age: postnatal day 0
Image: S1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:5474579
Age: embryonic day 18.0
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:5474579
Age: embryonic day 17.0
Image: S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474489
Age: postnatal day 22
Image: 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474489
Age: postnatal day 5
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474489
Age: postnatal day 4
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474489
Age: postnatal day 3
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474489
Age: postnatal day 2
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474489
Age: postnatal day 1
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5474483
Assay Type: RT-PCR
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5474489
Age: postnatal day 0
Image: 1
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3553528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474599
Age: postnatal day 28
Image: S2B UM
Note: Expression is in hair cells. Staining is low in the central zone.
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2013-04-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3553528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474599
Age: postnatal day 28
Image: S2A UM
Note: Expression is in type I and II hair cells.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3553527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5474490
Age: postnatal day 1
Image: 1C Vestibule
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474490
Age: postnatal day 5
Note: Expression is in hair cells.
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2013-04-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3553428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474599
Age: postnatal day 28
Image: S2A SM
Note: Expression is in type I and II hair cells.
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474599
Age: postnatal day 28
Image: S2B ACA
Note: Expression is in hair cells. Staining is low in the central zone.
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2013-04-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3279128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5474599
Age: postnatal day 28
Image: S2A ACA
Note: Expression is in type I and II hair cells.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5474490
Age: postnatal day 1
Image: 1C Vestibule
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5474490
Age: postnatal day 5
Detected: false
Specimen Num: 5
GXD Expression
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5474490
Age: postnatal day 1
Image: 1C Cochlea Base
Note: Expression is in inner and outer hair cells of the basal cochlear turn, less in the middle turn, absent in hair cells of the apical turn.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5474490
Age: postnatal day 1
Image: 1C Cochlea Apex
Note: Expression is in inner and outer hair cells of the basal cochlear turn, less in the middle turn, absent in hair cells of the apical turn.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5474484
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5474490
Age: postnatal day 1
Image: 1C Cochlea left
Note: Expression is in inner and outer hair cells of the basal cochlear turn, less in the middle turn, absent in hair cells of the apical turn.
Detected: true
Specimen Num: 2
Publication
First Author: Pan B
Year: 2018
Journal: Neuron
Title: TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.
Volume: 99
Issue: 4
Pages: 736-753.e6
Publication
First Author: Shibata SB
Year: 2016
Journal: Am J Hum Genet
Title: RNA Interference Prevents Autosomal-Dominant Hearing Loss.
Volume: 98
Issue: 6
Pages: 1101-1113
Publication
First Author: Beurg M
Year: 2018
Journal: Nat Commun
Title: Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea.
Volume: 9
Issue: 1
Pages: 2185
Publication
First Author: Beurg M
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells.
Volume: 113
Issue: 24
Pages: 6767-72
Publication
First Author: Corns LF
Year: 2016
Journal: J Neurosci
Title: Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.
Volume: 36
Issue: 2
Pages: 336-49
Publication
First Author: Gao X
Year: 2018
Journal: Nature
Title: Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Volume: 553
Issue: 7687
Pages: 217-221
Publication
First Author: Beurg M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Subunit determination of the conductance of hair-cell mechanotransducer channels.
Volume: 112
Issue: 5
Pages: 1589-94
Publication
First Author: Zhao B
Year: 2014
Journal: Neuron
Title: TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells.
Volume: 84
Issue: 5
Pages: 954-67
Publication
First Author: Noguchi Y
Year: 2006
Journal: Genetics
Title: Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.
Volume: 173
Issue: 4
Pages: 2111-9
Publication
First Author: Wu Z
Year: 2017
Journal: Nat Neurosci
Title: Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.
Volume: 20
Issue: 1
Pages: 24-33
Publication
First Author: Keresztes G
Year: 2003
Journal: BMC Genomics
Title: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
Volume: 4
Issue: 1
Pages: 24
Publication    
First Author: Cunningham CL
Year: 2017
Journal: Elife
Title: The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.
Volume: 6
Publication
First Author: Kurima K
Year: 2003
Journal: Genomics
Title: Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.
Volume: 82
Issue: 3
Pages: 300-8
Publication
First Author: Du TT
Year: 2019
Journal: Nat Commun
Title: LMO7 deficiency reveals the significance of the cuticular plate for hearing function.
Volume: 10
Issue: 1
Pages: 1117
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics, the Protein Information Resource and the Protein Ontology Consortium
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project