Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
204
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
111
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
125
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
45
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2020 |
Journal: |
Cell Host Microbe |
Title: |
TMEM173 Drives Lethal Coagulation in Sepsis. |
Volume: |
27 |
Issue: |
4 |
Pages: |
556-570.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel S |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele. |
Volume: |
198 |
Issue: |
2 |
Pages: |
776-787 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
199
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
372
|
Fragment?: |
false |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
E-GEOD-68140 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Surpris G |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Novel Tmem173 Allele Reveals Importance of STING N Terminus in Trafficking and Type I IFN Production. |
Volume: |
196 |
Issue: |
2 |
Pages: |
547-52 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
378
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; targeted mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng M |
Year: |
2022 |
Journal: |
Biochem Pharmacol |
Title: |
Gelsevirine improves age-related and surgically induced osteoarthritis in mice by reducing STING availability and local inflammation. |
Volume: |
198 |
|
Pages: |
114975 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; targeted mutation 3.1, Genoway |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 1, Jonathan Miner |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
378
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
427
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
337
|
Fragment?: |
false |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sting1/Sting1<+> |
Background: |
involves: C57BL/6N |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Park SM |
Year: |
2019 |
Journal: |
Commun Biol |
Title: |
T cell fate following Salmonella infection is determined by a STING-IRF1 signaling axis in mice. |
Volume: |
2 |
|
Pages: |
464 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cerboni S |
Year: |
2017 |
Journal: |
J Exp Med |
Title: |
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. |
Volume: |
214 |
Issue: |
6 |
Pages: |
1769-1785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertaux F |
Year: |
2022 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct Data Submission for Knock-in Genoway Alleles. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ruiz-Moreno JS |
Year: |
2018 |
Journal: |
Infect Immun |
Title: |
The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans. |
Volume: |
86 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|