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Search results 1 to 90 out of 90 for Tmem67

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
91147 | TMEM67
Type: gene
Organism: human
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Gene
506762 | TMEM67
Type: gene
Organism: cattle
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Gene
420224 | TMEM67
Type: gene
Organism: chicken
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Gene
572194 | tmem67
Type: gene
Organism: zebrafish
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Gene
698631 | TMEM67
Type: gene
Organism: macaque, rhesus
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Gene
100492945 | tmem67
Type: gene
Organism: frog, western clawed
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Gene
313067 | Tmem67
Type: gene
Organism: rat
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Gene
487049 | TMEM67
Type: gene
Organism: dog, domestic
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Gene
472937 | TMEM67
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1923928 | Tmem67
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23456819 | J:318964
First Author: Du E
Year: 2013
Journal: Cell Biol Int
Title: Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways.
Volume: 37
Issue: 7
Pages: 694-702
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Publication
30931988 | J:278544
First Author: Abdelhamed ZA
Year: 2019
Journal: Sci Rep
Title: The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/β-catenin signalling in the developing cerebellum via Hoxb5.
Volume: 9
Issue: 1
Pages: 5446
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Publication
26035863 | J:223384
First Author: Abdelhamed ZA
Year: 2015
Journal: Dis Model Mech
Title: The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.
Volume: 8
Issue: 6
Pages: 527-41
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Publication
22247471 | J:196773
First Author: Collin GB
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Meckelin is necessary for photoreceptor intraciliary transport and outer segment morphogenesis.
Volume: 53
Issue: 2
Pages: 967-74
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Publication
23393159 | J:194966
First Author: Leightner AC
Year: 2013
Journal: Hum Mol Genet
Title: The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.
Volume: 22
Issue: 10
Pages: 2024-40
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Publication
21725307 | J:176174
First Author: Garcia-Gonzalo FR
Year: 2011
Journal: Nat Genet
Title: A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Volume: 43
Issue: 8
Pages: 776-84
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Publication
23283079 | J:193837
First Author: Abdelhamed ZA
Year: 2013
Journal: Hum Mol Genet
Title: Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.
Volume: 22
Issue: 7
Pages: 1358-72
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Protein Coding Gene
MGP_CAROLIEiJ_G0025815 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027983 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1923928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027985 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027874 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027292 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023939 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026764 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19515853 | J:151414
First Author: Tammachote R
Year: 2009
Journal: Hum Mol Genet
Title: Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.
Volume: 18
Issue: 17
Pages: 3311-23
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Publication
19815549 | J:159051
First Author: Wang M
Year: 2009
Journal: J Biol Chem
Title: Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C.
Volume: 284
Issue: 48
Pages: 33377-83
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GXD Expression
GXD Expression
     
Probe: MGI:4939262
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939455
Age: embryonic day 18.5
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4939262
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939455
Age: embryonic day 18.5
Specimen Label: Vangl2Lp/Lp
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5439972
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689621
Pattern: Punctate
Stage: TS21
Assay Id: MGI:5439974
Age: embryonic day 13.5
Note: There is a discrete, punctuate-basal body-like staining pattern.
Specimen Label: 6B third ventricle wt
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5439972
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-30
Strength: Present
Sex: Male
Emaps: EMAPS:1689621
Pattern: Diffuse
Stage: TS21
Assay Id: MGI:5439974
Age: embryonic day 13.5
Note: Protein distribution was disrupted and diffuse in this mutant.
Specimen Label: 6B third ventricle Dilp2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5439972
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5439974
Age: embryonic day 13.5
Note: Expression is as a distinct layer at the apical cell surface.
Specimen Label: 6B lateral ventricle wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5439972
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-30
Strength: Present
Sex: Male
Emaps: EMAPS:3291221
Pattern: Diffuse
Stage: TS21
Assay Id: MGI:5439974
Age: embryonic day 13.5
Note: Protein distribution was disrupted and diffuse in this mutant.
Specimen Label: 6B lateral ventricle Dilp2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5816830
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5816828
Age: postnatal day 0
Image: 2D
Note: Expression was detected in the proximal regions of cilia in both hair-cell types and supporting cells. Magnified inset shows ciliary immunolocalization in a single outer hair cell (arrow) and an adjacent Deiters' cell (arrowhead).
Specimen Label: 2D
Detected: true
Specimen Num: 1
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Publication
17185389 | J:159145
First Author: Dawe HR
Year: 2007
Journal: Hum Mol Genet
Title: The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.
Volume: 16
Issue: 2
Pages: 173-86
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Publication
19596800 | J:153287
First Author: Dawe HR
Year: 2009
Journal: J Cell Sci
Title: Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.
Volume: 122
Issue: Pt 15
Pages: 2716-26
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Publication
22121117 | J:181150
First Author: Adams M
Year: 2012
Journal: Hum Mol Genet
Title: A meckelin-filamin A interaction mediates ciliogenesis.
Volume: 21
Issue: 6
Pages: 1272-86
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Publication
27002738 | J:231949
 
First Author: San Agustin JT
Year: 2016
Journal: Nat Commun
Title: Genetic link between renal birth defects and congenital heart disease.
Volume: 7
Pages: 11103
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Publication
34672258 | J:314668
   
First Author: Abrams SR
Year: 2021
Journal: Elife
Title: Ciliary Hedgehog signaling regulates cell survival to build the facial midline.
Volume: 10
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Publication
20843830 | J:166958
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
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Publication
25807483 | J:222159
First Author: Li Y
Year: 2015
Journal: Nature
Title: Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Volume: 521
Issue: 7553
Pages: 520-4
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Publication
- | J:175213
     
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:5451038 | B6;129P2-Tmem67<tm1Dgen>/H
Attribute String: targeted mutation, mutant stock
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DO Term
DOID:0070117 | Meckel syndrome 3
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DO Term
DOID:0111118 | nephronophthisis 11
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DO Term
DOID:0111001 | Joubert syndrome 6
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Allele
bpck | MGI:3688712
 
Name: bilateral polycystic kidney deletion region; bilateral polycystic kidneys
Allele Type: Spontaneous
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Allele
Tmem67<tm1Dgen> | MGI:5292220
Name: transmembrane protein 67; targeted mutation 1, Deltagen
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: bpck/bpck
Background: B6C3Fe a/a-bpck/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem67/Tmem67
Background: B6.129P2-Tmem67
Zygosity: hm
Has Mutant Allele: true
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Publication
19211713 | J:144929
First Author: Cook SA
Year: 2009
Journal: J Am Soc Nephrol
Title: A mouse model for Meckel syndrome type 3.
Volume: 20
Issue: 4
Pages: 753-64
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Strain
MGI:3832874 | B6C3Fe a/a-bpck/J
Attribute String: mutant stock, spontaneous mutation, deletion
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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