Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Tropomodulin (Tmod) family consist of four Tmods (Tmods 1-4) and three larger variants termed leiomodins (Lmods 1-3), which are expressed in a tissue-specific and developmentally regulated fashion []. Members of the Tmod family are actin filament pointed-end-capping proteins that regulate actin subunit association and dissociation from pointed ends in a tropomyosin-dependent manner [].Tropomodulin1 (Tmod1) was originally known to as E-Tmod, as it was first identified as a binding partner of tropomyosin (TM) in red blood cells (RBC) []. Tmod1 is predominantly expressed in terminally differentiated, post-mitotic cells (such as RBCs, lens fibre cells, neurons, andstriated muscle). Tmod1 binds with F-actin []. It is essential for stabilising F-actin at cell-cell junctions, which may be required for maintenance of cell shapes during embryonic cardiac morphogenesis []. It also regulates actin dynamics to control the precise lengths of the long alpha/beta tropomyosin-coated actin filaments in mature cardiac myofibrils [, ]. Tmod1 and Tmod4 maintain thin filament stability and correctly specified thin filament lengths in cardiac muscles via their interactions with terminal tropomyosins and their ability to regulate actin subunit exchange at pointed ends []. Tmod1's structure has been solved []. |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3821358 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3826028 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 Tmod1 |
|
Specimen Label: |
Additional file 4 Tmod1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKeown CR |
Year: |
2014 |
Journal: |
Dev Dyn |
Title: |
Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. |
Volume: |
243 |
Issue: |
6 |
Pages: |
800-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhin DS |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e48734 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhin DS |
Year: |
2014 |
Journal: |
Mol Biol Cell |
Title: |
Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle. |
Volume: |
25 |
Issue: |
6 |
Pages: |
852-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sung LA |
Year: |
1992 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein. |
Volume: |
267 |
Issue: |
4 |
Pages: |
2616-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lewis RA |
Year: |
2014 |
Journal: |
Cytoskeleton (Hoboken) |
Title: |
Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3. |
Volume: |
71 |
Issue: |
7 |
Pages: |
395-411 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mudry RE |
Year: |
2003 |
Journal: |
J Cell Biol |
Title: |
The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes. |
Volume: |
162 |
Issue: |
6 |
Pages: |
1057-68 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
47
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao JN |
Year: |
2014 |
Journal: |
Science |
Title: |
Mechanism of actin filament pointed-end capping by tropomodulin. |
Volume: |
345 |
Issue: |
6195 |
Pages: |
463-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kostyukova AS |
Year: |
2008 |
Journal: |
Biochemistry (Mosc) |
Title: |
Capping complex formation at the slow-growing end of the actin filament. |
Volume: |
73 |
Issue: |
13 |
Pages: |
1467-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
359
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamashiro S |
Year: |
2012 |
Journal: |
Cytoskeleton (Hoboken) |
Title: |
Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types. |
Volume: |
69 |
Issue: |
6 |
Pages: |
337-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber A |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Tropomodulin increases the critical concentration of barbed end-capped actin filaments by converting ADP.P(i)-actin to ADP-actin at all pointed filament ends. |
Volume: |
274 |
Issue: |
49 |
Pages: |
34637-45 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610515 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7580870 |
Age: |
embryonic day 9.5 |
Image: |
7 E9.5 |
Note: |
In E9.5 embryos, the Tmod1-positive striations were sharper and better defined, similar to Tmod1 in mature myofibrils. |
Specimen Label: |
7 E9.5 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610515 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7580870 |
Age: |
embryonic day 9.5 |
Image: |
7 E9.5 |
Note: |
In E9.5 embryos, the Tmod1-positive striations were sharper and better defined, similar to Tmod1 in mature myofibrils. |
Specimen Label: |
7 E9.5 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhin DS |
Year: |
2015 |
Journal: |
Development |
Title: |
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle. |
Volume: |
142 |
Issue: |
24 |
Pages: |
4351-62 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268812 |
Pattern: |
Not Specified |
Stage: |
TS12 |
Assay Id: |
MGI:7580870 |
Age: |
embryonic day 8.0-8.5 |
Image: |
6 E8-8.5 |
Note: |
In cardiac myocytes staining was frequently concentrated between periodic dots of sarcomeric alpha-actinin (Actn2), suggesting Tmod1 association with thin filament pointed ends between I-Z-I complexes in nascent myofibrils. |
Specimen Label: |
6 E8-8.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268812 |
Pattern: |
Not Specified |
Stage: |
TS12 |
Assay Id: |
MGI:7580870 |
Age: |
embryonic day 8.0-8.5 |
Image: |
6 E8-8.5 |
Note: |
In cardiac myocytes staining was frequently concentrated between periodic dots of sarcomeric alpha-actinin (Actn2), suggesting Tmod1 association with thin filament pointed ends between I-Z-I complexes in nascent myofibrils. |
Specimen Label: |
6 E8-8.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nowak RB |
Year: |
2009 |
Journal: |
J Cell Biol |
Title: |
Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens. |
Volume: |
186 |
Issue: |
6 |
Pages: |
915-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhin DS |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers. |
Volume: |
194 |
Issue: |
1 |
Pages: |
105-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKeown CR |
Year: |
2008 |
Journal: |
Circ Res |
Title: |
Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development. |
Volume: |
103 |
Issue: |
11 |
Pages: |
1241-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moyer JD |
Year: |
2010 |
Journal: |
Blood |
Title: |
Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton. |
Volume: |
116 |
Issue: |
14 |
Pages: |
2590-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhin DS |
Year: |
2010 |
Journal: |
J Cell Biol |
Title: |
Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. |
Volume: |
189 |
Issue: |
1 |
Pages: |
95-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sussman MA |
Year: |
1999 |
Journal: |
Am J Pathol |
Title: |
Pathogenesis of dilated cardiomyopathy: molecular, structural, and population analyses in tropomodulin-overexpressing transgenic mice. |
Volume: |
155 |
Issue: |
6 |
Pages: |
2101-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nowak RB |
Year: |
2012 |
Journal: |
J Histochem Cytochem |
Title: |
Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex. |
Volume: |
60 |
Issue: |
6 |
Pages: |
414-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng C |
Year: |
2015 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells. |
Volume: |
308 |
Issue: |
10 |
Pages: |
C835-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nowak RB |
Year: |
2017 |
Journal: |
Blood |
Title: |
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome. |
Volume: |
130 |
Issue: |
9 |
Pages: |
1144-1155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono Y |
Year: |
2005 |
Journal: |
Dev Biol |
Title: |
Disruption in the tropomodulin1 (Tmod1) gene compromises cardiomyocyte development in murine embryonic stem cells by arresting myofibril maturation. |
Volume: |
282 |
Issue: |
2 |
Pages: |
336-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fritz-Six KL |
Year: |
2003 |
Journal: |
J Cell Biol |
Title: |
Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. |
Volume: |
163 |
Issue: |
5 |
Pages: |
1033-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ochala J |
Year: |
2014 |
Journal: |
FASEB J |
Title: |
Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers. |
Volume: |
28 |
Issue: |
1 |
Pages: |
408-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng C |
Year: |
2016 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells. |
Volume: |
57 |
Issue: |
10 |
Pages: |
4084-99 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu X |
Year: |
2000 |
Journal: |
Gene |
Title: |
Genomic organization of mouse and human erythrocyte tropomodulin genes encoding the pointed end capping protein for the actin filaments. |
Volume: |
256 |
Issue: |
1-2 |
Pages: |
271-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu X |
Year: |
2003 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation. |
Volume: |
284 |
Issue: |
5 |
Pages: |
H1827-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watakabe A |
Year: |
1996 |
Journal: |
J Cell Sci |
Title: |
N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. |
Volume: |
109 ( Pt 9) |
|
Pages: |
2299-310 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:4438058 |
Age: |
embryonic day 8.5 |
|
|
Specimen Label: |
Tg- Tmod1+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:4438058 |
Age: |
embryonic day 8.5 |
|
|
Specimen Label: |
Tg- Tmod+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:4438058 |
Age: |
embryonic day 8.5 |
|
|
Specimen Label: |
Tg- Tmod1-/- |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608514 |
|
Stage: |
TS14 |
Assay Id: |
MGI:4438061 |
Age: |
embryonic day 8.5-9.5 |
|
|
Specimen Label: |
Tg- Tmod1+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608514 |
|
Stage: |
TS14 |
Assay Id: |
MGI:4438061 |
Age: |
embryonic day 8.5-9.5 |
|
|
Specimen Label: |
Tg- Tmod1+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608514 |
|
Stage: |
TS14 |
Assay Id: |
MGI:4438061 |
Age: |
embryonic day 8.5-9.5 |
|
|
Specimen Label: |
Tg- Tmod1+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608514 |
|
Stage: |
TS14 |
Assay Id: |
MGI:4438061 |
Age: |
embryonic day 8.5-9.5 |
|
|
Specimen Label: |
Tg- Tmod1-/- |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4438063 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Tg- Tmod+/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4438063 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Tg- Tmod+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2010-03-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1633223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4438063 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Tg- Tmod+/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
WT 1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
WT 2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
WT 3 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
WT 4 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
KO 1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
KO 2 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
KO 3 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
KO 4 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6435649 |
Assay Type: |
Western blot |
Annotation Date: |
2020-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6435764 |
Age: |
postnatal day 9 |
Image: |
S6 |
|
Specimen Label: |
KO 5 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7437842 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1759721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7437879 |
Age: |
embryonic day 13.5 |
Image: |
2 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7437842 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1759723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7437879 |
Age: |
embryonic day 15.5 |
Image: |
2 |
|
Specimen Label: |
E15.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7437842 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1759725 |
|
Stage: |
TS25 |
Assay Id: |
MGI:7437879 |
Age: |
embryonic day 17.5 |
Image: |
2 |
|
Specimen Label: |
E17.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7568995 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569019 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Tmod3+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7568995 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569019 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Tmod3+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7568995 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569019 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Tmod3-/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2023-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7569024 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:7580859 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438055 |
Assay Type: |
Western blot |
Annotation Date: |
2024-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:7580859 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|