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Search results 1 to 100 out of 148 for Tmprss6

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Du X
Year: 2008
Journal: Science
Title: The serine protease TMPRSS6 is required to sense iron deficiency.
Volume: 320
Issue: 5879
Pages: 1088-92
Publication
First Author: Guo S
Year: 2013
Journal: J Clin Invest
Title: Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
Volume: 123
Issue: 4
Pages: 1531-41
Publication
First Author: Finberg KE
Year: 2011
Journal: Blood
Title: Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
Volume: 117
Issue: 17
Pages: 4590-9
Publication
First Author: Nai A
Year: 2012
Journal: Blood
Title: Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.
Volume: 119
Issue: 21
Pages: 5021-9
Publication
First Author: Finberg KE
Year: 2010
Journal: Blood
Title: Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
Volume: 115
Issue: 18
Pages: 3817-26
Publication
First Author: Schmidt PJ
Year: 2013
Journal: Blood
Title: An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.
Volume: 121
Issue: 7
Pages: 1200-8
Publication      
First Author: Du X
Year: 2008
Journal: MGI Direct Data Submission
Title: Zorro is a mutation of Tmprss6
Publication
First Author: Stagg DB
Year: 2019
Journal: Haematologica
Title: Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia.
Volume: 104
Issue: 10
Pages: e442-e446
Publication
First Author: Frýdlová J
Year: 2016
Journal: PLoS One
Title: Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats.
Volume: 11
Issue: 2
Pages: e0148540
Publication
First Author: Lee P
Year: 2012
Journal: Blood Cells Mol Dis
Title: Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6.
Volume: 48
Issue: 3
Pages: 173-8
Publication
First Author: Frýdlová J
Year: 2017
Journal: PLoS One
Title: Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.
Volume: 12
Issue: 10
Pages: e0186844
Publication  
First Author: Gnana-Prakasam JP
Year: 2014
Journal: Mol Vis
Title: Retinal expression of the serine protease matriptase-2 (Tmprss6) and its role in retinal iron homeostasis.
Volume: 20
Pages: 561-74
Publication  
First Author: Krijt J
Year: 2021
Journal: Int J Mol Sci
Title: Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice.
Volume: 22
Issue: 5
Publication
First Author: Truksa J
Year: 2009
Journal: Br J Haematol
Title: Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.
Volume: 147
Issue: 4
Pages: 571-81
Publication
First Author: Frýdlová J
Year: 2019
Journal: PLoS One
Title: Effect of stimulated erythropoiesis on liver SMAD signaling pathway in iron-overloaded and iron-deficient mice.
Volume: 14
Issue: 4
Pages: e0215028
Publication
First Author: Riba M
Year: 2013
Journal: PLoS One
Title: A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice.
Volume: 8
Issue: 7
Pages: e69694
Publication
First Author: Zhang AS
Year: 2011
Journal: Blood
Title: Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein.
Volume: 117
Issue: 5
Pages: 1687-99
Publication
First Author: Folgueras AR
Year: 2018
Journal: Nat Commun
Title: Matriptase-2 deficiency protects from obesity by modulating iron homeostasis.
Volume: 9
Issue: 1
Pages: 1350
Publication
First Author: Casu C
Year: 2020
Journal: Blood
Title: Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
Volume: 136
Issue: 17
Pages: 1968-1979
Publication
First Author: Hanudel MR
Year: 2022
Journal: Kidney Int
Title: Enteral ferric citrate absorption is dependent on the iron transport protein ferroportin.
Volume: 101
Issue: 4
Pages: 711-719
Publication
First Author: Frýdlová J
Year: 2013
Journal: Physiol Res
Title: Decreased hemojuvelin protein levels in mask mice lacking matriptase-2-dependent proteolytic activity.
Volume: 62
Issue: 4
Pages: 405-11
Publication
First Author: Jin L
Year: 2019
Journal: Metallomics
Title: Mice overexpressing hepcidin suggest ferroportin does not play a major role in Mn homeostasis.
Volume: 11
Issue: 5
Pages: 959-967
Publication
First Author: Nai A
Year: 2016
Journal: Blood
Title: Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Volume: 127
Issue: 19
Pages: 2327-36
Publication
First Author: Rausa M
Year: 2015
Journal: PLoS One
Title: Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?
Volume: 10
Issue: 4
Pages: e0122696
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Reyna C
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for ekans
Publication      
First Author: Reyna C
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for cubone
Publication      
First Author: Blasius AL
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "masquerade", updated 21st of January, 2009
Publication
First Author: Folgueras AR
Year: 2008
Journal: Blood
Title: Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis.
Volume: 112
Issue: 6
Pages: 2539-45
Publication
First Author: Nai A
Year: 2010
Journal: Blood
Title: Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice.
Volume: 116
Issue: 5
Pages: 851-2
Publication
First Author: Bartnikas TB
Year: 2013
Journal: Haematologica
Title: Identification and characterization of a novel murine allele of Tmprss6.
Volume: 98
Issue: 6
Pages: 854-61
Publication
First Author: Xavier-Ferrucio J
Year: 2019
Journal: Blood
Title: Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.
Volume: 134
Issue: 18
Pages: 1547-1557
Publication
First Author: Velasco G
Year: 2002
Journal: J Biol Chem
Title: Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.
Volume: 277
Issue: 40
Pages: 37637-46
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Uterus
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Stomach
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Intestine
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:5689877
Age: postnatal adult
Specimen Label: Pancreas
Detected: true
Specimen Num: 12
GXD Expression        
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5689883
Age: embryonic day 7.5
Specimen Label: E7.5
Specimen Num: 2
GXD Expression        
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5689883
Age: embryonic day 8.5
Specimen Label: E8.5
Specimen Num: 3
GXD Expression        
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5689883
Age: embryonic day 9.5
Specimen Label: E9.5
Specimen Num: 4
GXD Expression        
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5689883
Age: embryonic day 10.5
Specimen Label: E10.5
Specimen Num: 5
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5689883
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5689883
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5689808
Assay Type: RT-PCR
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5689883
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Uniform
Stage: TS28
Assay Id: MGI:5689880
Age: postnatal adult
Note: Expressed in hepatocytes.
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5689880
Age: postnatal adult
Note: Expressed throughout the kidney.
Specimen Label: 6C
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3530828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5689880
Age: postnatal adult
Specimen Label: 6I
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2991528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5689880
Age: postnatal adult
Note: Predominantly expressed by glandular columnar epithelial cells.
Specimen Label: 6I
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5689880
Age: embryonic day 12.5
Specimen Label: 8A
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: 8B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5689880
Age: embryonic day 12.5
Specimen Label: 8A
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: 8B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: 8C
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:5689880
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672320
Stage: TS20
Assay Id: MGI:5689880
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672323
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5689880
Age: embryonic day 15.5
Specimen Label: 8B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5689810
Assay Type: RNA in situ
Annotation Date: 2015-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608520
Stage: TS20
Assay Id: MGI:5689880
Age: embryonic day 12.5
Note: Background levels.
Specimen Label: 8A
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7423865
Assay Type: RNA in situ
Annotation Date: 2023-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425409
Age: embryonic day 16.5
Specimen Label: File S3
Detected: true
Specimen Num: 1
Publication
First Author: Hooper JD
Year: 2003
Journal: Biochem J
Title: Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues.
Volume: 373
Issue: Pt 3
Pages: 689-702
Publication
First Author: Lenoir A
Year: 2011
Journal: Blood
Title: Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.
Volume: 117
Issue: 2
Pages: 647-50
Publication
First Author: Enns CA
Year: 2020
Journal: Blood
Title: The ectodomain of matriptase-2 plays an important nonproteolytic role in suppressing hepcidin expression in mice.
Volume: 136
Issue: 8
Pages: 989-1001
Publication
First Author: Frazer DM
Year: 2017
Journal: Cell Mol Gastroenterol Hepatol
Title: Ferroportin Is Essential for Iron Absorption During Suckling, But Is Hyporesponsive to the Regulatory Hormone Hepcidin.
Volume: 3
Issue: 3
Pages: 410-421
Publication
First Author: Pagani A
Year: 2011
Journal: Blood
Title: Low hepcidin accounts for the proinflammatory status associated with iron deficiency.
Volume: 118
Issue: 3
Pages: 736-46