|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 609 for Tnfaip3

<< First    < Previous  |  Next >    Last >>
0.046s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Liu L
Year: 2022
Journal: Mol Vis
Title: TNFAIP3 is anti-inflammatory in the retinal vasculature.
Volume: 28
Pages: 124-129
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication  
First Author: Zammit NW
Year: 2022
Journal: Front Immunol
Title: TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation.
Volume: 13
Pages: 811525
Publication  
First Author: Montarolo F
Year: 2020
Journal: Int J Mol Sci
Title: TNFAIP3 Deficiency Affects Monocytes, Monocytes-Derived Cells and Microglia in Mice.
Volume: 21
Issue: 8
Publication
First Author: Zammit NW
Year: 2019
Journal: Nat Immunol
Title: Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Volume: 20
Issue: 10
Pages: 1299-1310
Publication
First Author: Kolodziej LE
Year: 2011
Journal: PLoS One
Title: TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions.
Volume: 6
Issue: 10
Pages: e26352
Publication  
First Author: Smith MA
Year: 2020
Journal: Front Immunol
Title: TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Volume: 11
Pages: 536442
Publication
First Author: Matsuzawa Y
Year: 2015
Journal: Autophagy
Title: TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy.
Volume: 11
Issue: 7
Pages: 1052-62
Publication
First Author: Rhee L
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis.
Volume: 303
Issue: 2
Pages: G220-7
Publication  
First Author: Liu L
Year: 2022
Journal: Exp Eye Res
Title: TNFAIP3 may be key to TLR4-activation of the inflammasome in the retinal vasculature.
Volume: 220
Pages: 109108
Publication
First Author: Lai TY
Year: 2013
Journal: PLoS One
Title: Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages.
Volume: 8
Issue: 9
Pages: e73153
Publication
First Author: Sokhi UK
Year: 2018
Journal: Nat Commun
Title: Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.
Volume: 9
Issue: 1
Pages: 658
Publication
First Author: Murphy SF
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.
Volume: 307
Issue: 9
Pages: G871-82
Publication
First Author: Oshima S
Year: 2009
Journal: Nature
Title: ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development.
Volume: 457
Issue: 7231
Pages: 906-9
Publication
First Author: Heyninck K
Year: 1999
Journal: J Cell Biol
Title: The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.
Volume: 145
Issue: 7
Pages: 1471-82
Publication
First Author: Heyninck K
Year: 2003
Journal: FEBS Lett
Title: Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1.
Volume: 536
Issue: 1-3
Pages: 135-40
Publication
First Author: Van Huffel S
Year: 2001
Journal: J Biol Chem
Title: Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.
Volume: 276
Issue: 32
Pages: 30216-23
Publication
First Author: Kattah MG
Year: 2018
Journal: J Exp Med
Title: A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival.
Volume: 215
Issue: 7
Pages: 1839-1852
Publication  
First Author: Rusu I
Year: 2022
Journal: J Clin Invest
Title: Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage.
Volume: 132
Issue: 5
Publication
First Author: Liu D
Year: 2020
Journal: Cell Metab
Title: TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation.
Volume: 31
Issue: 4
Pages: 726-740.e8
Publication
First Author: Dziedzic SA
Year: 2018
Journal: Nat Cell Biol
Title: ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.
Volume: 20
Issue: 1
Pages: 58-68
Publication
First Author: Kool M
Year: 2011
Journal: Immunity
Title: The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.
Volume: 35
Issue: 1
Pages: 82-96
Publication
First Author: Aki A
Year: 2017
Journal: PLoS One
Title: Hypomorphic A20 expression confers susceptibility to psoriasis.
Volume: 12
Issue: 6
Pages: e0180481
Publication
First Author: Chu Y
Year: 2011
Journal: Blood
Title: B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.
Volume: 117
Issue: 7
Pages: 2227-36
Publication
First Author: Martens A
Year: 2020
Journal: Nat Immunol
Title: Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Volume: 21
Issue: 4
Pages: 381-387
Publication
First Author: Matmati M
Year: 2011
Journal: Nat Genet
Title: A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
Volume: 43
Issue: 9
Pages: 908-12
Publication
First Author: Tavares RM
Year: 2010
Journal: Immunity
Title: The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.
Volume: 33
Issue: 2
Pages: 181-91
Publication
First Author: Hövelmeyer N
Year: 2011
Journal: Eur J Immunol
Title: A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies.
Volume: 41
Issue: 3
Pages: 595-601
Publication  
First Author: Yokoyama Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: A20 (Tnfaip3) expressed in CD4+ T cells suppresses Th2 cell-mediated allergic airway inflammation in mice.
Volume: 629
Pages: 47-53
Publication
First Author: Fukaya M
Year: 2016
Journal: Mol Endocrinol
Title: A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.
Volume: 30
Issue: 1
Pages: 48-61
Publication
First Author: Xia M
Year: 2013
Journal: Immunity
Title: Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20.
Volume: 39
Issue: 3
Pages: 470-81
Publication
First Author: Mohebiany AN
Year: 2020
Journal: Cell Rep
Title: Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology.
Volume: 30
Issue: 5
Pages: 1585-1597.e6
Publication
First Author: Yuk JM
Year: 2015
Journal: Immunity
Title: Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation.
Volume: 43
Issue: 1
Pages: 80-91
Publication  
First Author: Ogando DG
Year: 2010
Journal: Mol Vis
Title: Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice.
Volume: 16
Pages: 1004-18
Publication
First Author: Giordano M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells.
Volume: 111
Issue: 30
Pages: 11115-20
Publication  
First Author: Soni D
Year: 2018
Journal: Cell Death Discov
Title: Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury.
Volume: 4
Pages: 60
Publication
First Author: Koudstaal T
Year: 2020
Journal: Am J Respir Cell Mol Biol
Title: DNGR1-Cre-mediated Deletion of Tnfaip3/A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice.
Volume: 63
Issue: 5
Pages: 665-680
Publication
First Author: Wang W
Year: 2022
Journal: Nat Commun
Title: Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs.
Volume: 13
Issue: 1
Pages: 6358
Publication
First Author: Billmann-Born S
Year: 2011
Journal: J Immunol
Title: Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.
Volume: 186
Issue: 7
Pages: 4027-38
Publication
First Author: Wertz IE
Year: 2015
Journal: Nature
Title: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
Volume: 528
Issue: 7582
Pages: 370-5
Publication
First Author: Sun Y
Year: 2017
Journal: J Exp Med
Title: Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos.
Volume: 214
Issue: 6
Pages: 1753-1767
Publication
First Author: Garcia-Carbonell R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.
Volume: 115
Issue: 39
Pages: E9192-E9200
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fischer JC
Year: 2017
Journal: J Immunol
Title: A20 Restrains Thymic Regulatory T Cell Development.
Volume: 199
Issue: 7
Pages: 2356-2365
Publication  
First Author: Just S
Year: 2016
Journal: Sci Rep
Title: A20 Curtails Primary but Augments Secondary CD8+ T Cell Responses in Intracellular Bacterial Infection.
Volume: 6
Pages: 39796
Publication
First Author: Wang X
Year: 2018
Journal: PLoS One
Title: Dysregulation of NF-kB in glandular epithelial cells results in Sjögren's-like features.
Volume: 13
Issue: 8
Pages: e0200212
Publication
First Author: Nagamachi A
Year: 2014
Journal: PLoS One
Title: Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function.
Volume: 9
Issue: 1
Pages: e87425
Publication
First Author: Maelfait J
Year: 2016
Journal: PLoS Pathog
Title: A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection.
Volume: 12
Issue: 1
Pages: e1005410
Publication
First Author: Schuijs MJ
Year: 2015
Journal: Science
Title: Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells.
Volume: 349
Issue: 6252
Pages: 1106-10
Publication
First Author: Xuan NT
Year: 2015
Journal: Eur J Immunol
Title: A20 expression in dendritic cells protects mice from LPS-induced mortality.
Volume: 45
Issue: 3
Pages: 818-28
Publication
First Author: Li Y
Year: 2019
Journal: J Immunol
Title: A20 Orchestrates Inflammatory Response in the Oral Mucosa through Restraining NF-κB Activity.
Volume: 202
Issue: 7
Pages: 2044-2056
Publication
First Author: Studer P
Year: 2015
Journal: Cell Death Differ
Title: Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration.
Volume: 22
Issue: 12
Pages: 2068-77
Publication
First Author: Lu X
Year: 2019
Journal: Circ Res
Title: A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.
Volume: 125
Issue: 12
Pages: 1055-1066
Publication
First Author: De A
Year: 2014
Journal: EMBO Rep
Title: The deubiquitinase activity of A20 is dispensable for NF-κB signaling.
Volume: 15
Issue: 7
Pages: 775-83
Publication
First Author: Liu SS
Year: 2019
Journal: Immunity
Title: Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages.
Volume: 51
Issue: 3
Pages: 522-534.e7
Publication
First Author: Meng Z
Year: 2017
Journal: J Immunol
Title: A20 Ameliorates Intracerebral Hemorrhage-Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination.
Volume: 198
Issue: 2
Pages: 820-831
Publication
First Author: Damrauer SM
Year: 2010
Journal: Atherosclerosis
Title: A20 inhibits post-angioplasty restenosis by blocking macrophage trafficking and decreasing adventitial neovascularization.
Volume: 211
Issue: 2
Pages: 404-8
Publication
First Author: Zeng W
Year: 2009
Journal: Biorheology
Title: A20 overexpression inhibits low shear flow-induced CD14-positive monocyte recruitment to endothelial cells.
Volume: 46
Issue: 1
Pages: 21-30
Publication
First Author: Li HL
Year: 2007
Journal: Circulation
Title: Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Volume: 115
Issue: 14
Pages: 1885-94
Publication
First Author: Wang J
Year: 2009
Journal: J Immunol
Title: Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes.
Volume: 183
Issue: 2
Pages: 1384-92
Publication
First Author: Hong B
Year: 2011
Journal: J Clin Invest
Title: Mucosal and systemic anti-HIV immunity controlled by A20 in mouse dendritic cells.
Volume: 121
Issue: 2
Pages: 739-51
Publication
First Author: Srivastav S
Year: 2012
Journal: J Immunol
Title: Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response.
Volume: 189
Issue: 2
Pages: 924-34
Publication
First Author: Tokunaga F
Year: 2012
Journal: EMBO J
Title: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.
Volume: 31
Issue: 19
Pages: 3856-70
Publication
First Author: Yamaguchi N
Year: 2015
Journal: FEBS Lett
Title: The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis.
Volume: 589
Issue: 12
Pages: 1369-75
Publication
First Author: Wang L
Year: 2012
Journal: PLoS One
Title: A20 controls macrophage to elicit potent cytotoxic CD4(+) T cell response.
Volume: 7
Issue: 11
Pages: e48930
Publication
First Author: Zhou J
Year: 2019
Journal: World J Gastroenterol
Title: Herbs-partitioned moxibustion alleviates aberrant intestinal epithelial cell apoptosis by upregulating A20 expression in a mouse model of Crohn's disease.
Volume: 25
Issue: 17
Pages: 2071-2085
Publication  
First Author: Das T
Year: 2019
Journal: J Autoimmun
Title: DNGR1-mediated deletion of A20/Tnfaip3 in dendritic cells alters T and B-cell homeostasis and promotes autoimmune liver pathology.
Volume: 102
Pages: 167-178
Publication  
First Author: Rohwedder I
Year: 2023
Journal: JCI Insight
Title: A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny.
Volume: 8
Issue: 4
GXD Expression      
Probe: MGI:7435570
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435602
Age: postnatal month 2
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7435570
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435602
Age: postnatal month 2
Specimen Label: Nrl<-/->
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4879273
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540974
Age: embryonic day 15.5
Image: GUDMAP:9362
Specimen Label: GUDMAP:9362
Detected: true
Specimen Num: 1