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Search results 1 to 100 out of 116 for Tnfsf15

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
9966 | TNFSF15
Type: gene
Organism: human
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Gene
100494382 | tnfsf15
Type: gene
Organism: frog, western clawed
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Gene
252878 | Tnfsf15
Type: gene
Organism: rat
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Gene
473468 | TNFSF15
Type: gene
Organism: chimpanzee
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Gene
481688 | TNFSF15
Type: gene
Organism: dog, domestic
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Gene
514239 | TNFSF15
Type: gene
Organism: cattle
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Gene
417247 | TNFSF15
Type: gene
Organism: chicken
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Gene
703189 | TNFSF15
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2180140 | Tnfsf15
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR008064 | TNFSF15
Type: Family
Description: Tumor necrosis factor ligand superfamily member 15 (TNFSF15) is a receptor for TNFRSF25 and TNFRSF6B. It mediates activation of NF-kappa-B and inhibits vascular endothelial growth and angiogenesis (in vitro). It also promotes activation of caspases and apoptosis [].
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Publication
23918400 | J:200756
First Author: Qi JW
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: TNFSF15 inhibits vasculogenesis by regulating relative levels of membrane-bound and soluble isoforms of VEGF receptor 1.
Volume: 110
Issue: 34
Pages: 13863-8
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Protein
Q5UBV8
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: false
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Protein
B2RR33
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: false
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Protein
A0A0U5J7F3
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: false
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Publication
11923219 | -
First Author: Chew LJ
Year: 2002
Journal: FASEB J
Title: A novel secreted splice variant of vascular endothelial cell growth inhibitor.
Volume: 16
Issue: 7
Pages: 742-4
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Publication
34596444 | J:322345
 
First Author: Yang GL
Year: 2021
Journal: ASN Neuro
Title: A Protective Role of Tumor Necrosis Factor Superfamily-15 in Intracerebral Hemorrhage-Induced Secondary Brain Injury.
Volume: 13
Pages: 17590914211038441
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Publication
31242765 | J:293984
First Author: Yang GL
Year: 2019
Journal: FASEB J
Title: Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15.
Volume: 33
Issue: 9
Pages: 10505-10514
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Publication
29335258 | J:257626
First Author: Ferdinand JR
Year: 2018
Journal: J Immunol
Title: Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells.
Volume: 200
Issue: 4
Pages: 1360-1369
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Publication
24850426 | J:279191
First Author: Shih DQ
Year: 2014
Journal: Mucosal Immunol
Title: Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis.
Volume: 7
Issue: 6
Pages: 1492-503
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Publication
26096340 | J:226195
First Author: Qin TT
Year: 2015
Journal: J Pathol
Title: Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells.
Volume: 237
Issue: 3
Pages: 307-18
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Publication
30552020 | J:295074
First Author: Castellanos JG
Year: 2018
Journal: Immunity
Title: Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.
Volume: 49
Issue: 6
Pages: 1077-1089.e5
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Protein Coding Gene
MGP_CAROLIEiJ_G0026097 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028069 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2180140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028153 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028830 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028435 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027063 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
38348035 | J:350740
 
First Author: Wang S
Year: 2024
Journal: Front Immunol
Title: Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis.
Volume: 15
Pages: 1340467
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Publication
18411337 | J:136280
First Author: Pappu BP
Year: 2008
Journal: J Exp Med
Title: TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease.
Volume: 205
Issue: 5
Pages: 1049-62
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Publication
32001795 | J:310884
First Author: Tougaard P
Year: 2020
Journal: Int J Obes (Lond)
Title: TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice.
Volume: 44
Issue: 5
Pages: 1062-1074
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Publication
25404161 | J:222309
First Author: Tougaard P
Year: 2015
Journal: Eur J Immunol
Title: TL1A regulates TCRγδ+ intraepithelial lymphocytes and gut microbial composition.
Volume: 45
Issue: 3
Pages: 865-75
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Publication
21264313 | J:169462
First Author: Shih DQ
Year: 2011
Journal: PLoS One
Title: Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis.
Volume: 6
Issue: 1
Pages: e16090
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Publication
34257516 | J:322350
 
First Author: Wenxiu J
Year: 2021
Journal: Mediators Inflamm
Title: Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis.
Volume: 2021
Pages: 5927064
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Publication
30949903 | J:295897
First Author: Yang M
Year: 2019
Journal: Dig Dis Sci
Title: Effects and Mechanism of Constitutive TL1A Expression on Intestinal Mucosal Barrier in DSS-Induced Colitis.
Volume: 64
Issue: 7
Pages: 1844-1856
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Publication
30906791 | J:291092
 
First Author: Guo J
Year: 2019
Journal: J Immunol Res
Title: Overexpression of Tumor Necrosis Factor-Like Ligand 1 A in Myeloid Cells Aggravates Liver Fibrosis in Mice.
Volume: 2019
Pages: 7657294
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Publication
29988118 | J:289236
First Author: Jacob N
Year: 2018
Journal: Mucosal Immunol
Title: Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome.
Volume: 11
Issue: 5
Pages: 1466-1476
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Publication
24140642 | J:207029
First Author: Wang X
Year: 2013
Journal: J Immunol
Title: TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses.
Volume: 191
Issue: 11
Pages: 5420-9
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Publication
34679191 | J:322241
First Author: Li J
Year: 2021
Journal: FASEB J
Title: Tumor necrosis factor ligand-related molecule 1A maintains blood-retinal barrier via modulating SHP-1-Src-VE-cadherin signaling in diabetic retinopathy.
Volume: 35
Issue: 11
Pages: e22008
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Publication
37099426 | J:342758
First Author: Fukaya T
Year: 2023
Journal: Cell Rep
Title: Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells.
Volume: 42
Issue: 5
Pages: 112431
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Publication
19329781 | J:148944
First Author: Tian F
Year: 2009
Journal: Blood
Title: Inhibition of endothelial progenitor cell differentiation by VEGI.
Volume: 113
Issue: 21
Pages: 5352-60
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Publication
32963108 | J:299470
First Author: Zhao D
Year: 2020
Journal: J Biol Chem
Title: TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.
Volume: 295
Issue: 48
Pages: 16314-16327
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Publication
24220298 | J:307006
First Author: Yu X
Year: 2014
Journal: Mucosal Immunol
Title: TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers.
Volume: 7
Issue: 3
Pages: 730-40
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GXD Expression
GXD Expression
   
Probe: MGI:7666456
Assay Type: RT-PCR
Annotation Date: 2024-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3515421
Stage: TS21
Assay Id: MGI:7666654
Age: embryonic day 13.5
Image: 4
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7666456
Assay Type: RT-PCR
Annotation Date: 2024-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3515421
Stage: TS21
Assay Id: MGI:7666654
Age: embryonic day 13.5
Image: 4
Specimen Label: DKO
Detected: true
Specimen Num: 2
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Publication
11911831 | J:75557
First Author: Migone TS
Year: 2002
Journal: Immunity
Title: TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.
Volume: 16
Issue: 3
Pages: 479-92
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Publication
27233964 | J:309816
First Author: Jia LG
Year: 2016
Journal: J Immunol
Title: A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.
Volume: 197
Issue: 1
Pages: 377-86
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Publication
18287561 | J:306758
First Author: Al-Lamki RS
Year: 2008
Journal: J Am Soc Nephrol
Title: TL1A both promotes and protects from renal inflammation and injury.
Volume: 19
Issue: 5
Pages: 953-60
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Publication
27664471 | J:238083
First Author: Perks WV
Year: 2016
Journal: Am J Pathol
Title: Death Receptor 3 Promotes Chemokine-Directed Leukocyte Recruitment in Acute Resolving Inflammation and Is Essential for Pathological Development of Mesothelial Fibrosis in Chronic Disease.
Volume: 186
Issue: 11
Pages: 2813-2823
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Publication
25399326 | J:307337
 
First Author: Wang J
Year: 2014
Journal: BMC Nephrol
Title: TL1-A can engage death receptor-3 and activate NF-kappa B in endothelial cells.
Volume: 15
Pages: 178
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Publication
33097818 | J:298964
First Author: Jacob N
Year: 2020
Journal: Sci Rep
Title: Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo.
Volume: 10
Issue: 1
Pages: 18189
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Publication
32958689 | J:303576
First Author: Herro R
Year: 2020
Journal: J Immunol
Title: TL1A Promotes Lung Tissue Fibrosis and Airway Remodeling.
Volume: 205
Issue: 9
Pages: 2414-2422
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Publication
20962771 | J:309882
First Author: Taraban VY
Year: 2011
Journal: Mucosal Immunol
Title: Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia.
Volume: 4
Issue: 2
Pages: 186-96
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Publication
37434162 | J:344363
First Author: Zhang D
Year: 2023
Journal: Respir Res
Title: Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption.
Volume: 24
Issue: 1
Pages: 182
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Publication
20826539 | J:167787
First Author: Jones GW
Year: 2011
Journal: FASEB J
Title: Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
Volume: 25
Issue: 1
Pages: 409-19
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Publication
38987753 | J:360431
First Author: Liu X
Year: 2024
Journal: Respir Res
Title: Necroptosis plays a role in TL1A-induced airway inflammation and barrier damage in asthma.
Volume: 25
Issue: 1
Pages: 271
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Publication
29254800 | J:295928
First Author: Li H
Year: 2018
Journal: Pathol Res Pract
Title: TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice.
Volume: 214
Issue: 2
Pages: 217-227
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Publication
23319737 | J:193316
First Author: Khan SQ
Year: 2013
Journal: J Immunol
Title: Cloning, expression, and functional characterization of TL1A-Ig.
Volume: 190
Issue: 4
Pages: 1540-50
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Publication
25786692 | J:315370
First Author: Richard AC
Year: 2015
Journal: J Immunol
Title: The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
Volume: 194
Issue: 8
Pages: 3567-82
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Publication
18598698 | J:141891
First Author: Takedatsu H
Year: 2008
Journal: Gastroenterology
Title: TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.
Volume: 135
Issue: 2
Pages: 552-67
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Publication
16698931 | J:110203
First Author: Bamias G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.
Volume: 103
Issue: 22
Pages: 8441-6
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Publication
20980995 | J:267887
First Author: Meylan F
Year: 2011
Journal: Mucosal Immunol
Title: The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.
Volume: 4
Issue: 2
Pages: 172-85
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Publication
38597952 | J:358507
 
First Author: Schmitt P
Year: 2024
Journal: J Exp Med
Title: TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation.
Volume: 221
Issue: 6
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Publication
12860530 | J:84635
First Author: Collette Y
Year: 2003
Journal: Trends Immunol
Title: A co-evolution perspective of the TNFSF and TNFRSF families in the immune system.
Volume: 24
Issue: 7
Pages: 387-94
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Publication
37702066 | J:341382
First Author: Wu B
Year: 2023
Journal: J Am Heart Assoc
Title: Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
Volume: 12
Issue: 18
Pages: e029683
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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