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Search results 1 to 100 out of 621 for Tnni3

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
key_980130 | Tnni3
Type: gene
Organism: Not Specified
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Gene
7137 | TNNI3
Type: gene
Organism: human
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Gene
511094 | TNNI3
Type: gene
Organism: cattle
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Gene
396428 | TNNI3
Type: gene
Organism: chicken
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Gene
698470 | TNNI3
Type: gene
Organism: macaque, rhesus
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Gene
496889 | tnni3
Type: gene
Organism: frog, western clawed
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Gene
29248 | Tnni3
Type: gene
Organism: rat
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Gene
403566 | TNNI3
Type: gene
Organism: dog, domestic
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Gene
735514 | TNNI3
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:98783 | Tnni3
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3825678
Age: embryonic day 14.5
Image: Additional file 4 Tnni3
Specimen Label: Additional file 4 Tnni3
Detected: false
Specimen Num: 1
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Gene
51086 | TNNI3K
Type: gene
Organism: human
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Protein Coding Gene
MGI:2443276 | Tnni3k
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
295531 | Tnni3k
Type: gene
Organism: rat
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Gene
535940 | TNNI3K
Type: gene
Organism: cattle
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Gene
100533996 | TNNI3K
Type: gene
Organism: dog, domestic
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Gene
100533985 | TNNI3K
Type: gene
Organism: chimpanzee
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Gene
100533999 | TNNI3K
Type: gene
Organism: chicken
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Gene
799621 | tnni3k
Type: gene
Organism: zebrafish
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Gene
100533987 | TNNI3K
Type: gene
Organism: macaque, rhesus
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Gene
100495062 | tnni3k
Type: gene
Organism: frog, western clawed
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Publication
16936010 | J:119966
First Author: Bilchick KC
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
Volume: 292
Issue: 1
Pages: H318-25
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Publication
37628941 | J:339644
 
First Author: Gu Q
Year: 2023
Journal: Int J Mol Sci
Title: Expression Levels of the Tnni3k Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways.
Volume: 24
Issue: 16
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Publication
37597489 | J:339970
 
First Author: Purdy AL
Year: 2023
Journal: J Mol Cell Cardiol
Title: Tnni3k influences cardiomyocyte S-phase activity and proliferation.
Volume: 183
Pages: 22-26
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Gene
108713524 | tnni3k.L
Type: gene
Organism: frog, African clawed
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Gene
108715511 | tnni3k.S
Type: gene
Organism: frog, African clawed
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Protein Coding Gene
MGP_CAROLIEiJ_G0029115 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031548 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031251 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030615 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030710 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020984 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030168 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8276817 | J:16384
First Author: Ausoni S
Year: 1994
Journal: J Biol Chem
Title: Structure and regulation of the mouse cardiac troponin I gene.
Volume: 269
Issue: 1
Pages: 339-46
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Publication
8195157 | J:31198
First Author: Guo X
Year: 1994
Journal: J Biol Chem
Title: Mutagenesis of cardiac troponin I. Role of the unique NH2-terminal peptide in myofilament activation.
Volume: 269
Issue: 21
Pages: 15210-6
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Publication
16950368 | J:114537
First Author: Tsoutsman T
Year: 2006
Journal: J Mol Cell Cardiol
Title: Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy.
Volume: 41
Issue: 4
Pages: 623-32
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Publication
22086914 | J:180606
First Author: Wang Y
Year: 2012
Journal: J Biol Chem
Title: Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy.
Volume: 287
Issue: 3
Pages: 2156-67
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Publication
25961037 | J:307877
 
First Author: Liang J
Year: 2015
Journal: Biomed Res Int
Title: The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice.
Volume: 2015
Pages: 742536
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Publication
24973218 | J:307879
First Author: Dweck D
Year: 2014
Journal: J Biol Chem
Title: Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy.
Volume: 289
Issue: 33
Pages: 23097-23111
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Publication
29669813 | J:264134
First Author: Martin-Garrido A
Year: 2018
Journal: J Biol Chem
Title: Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis.
Volume: 293
Issue: 22
Pages: 8588-8599
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Publication
11934831 | J:109759
First Author: Pi Y
Year: 2002
Journal: Circ Res
Title: Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice.
Volume: 90
Issue: 6
Pages: 649-56
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Publication
28066262 | J:243552
 
First Author: Liu X
Year: 2016
Journal: Front Physiol
Title: Restrictive Cardiomyopathy Caused by Troponin Mutations: Application of Disease Animal Models in Translational Studies.
Volume: 7
Pages: 629
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Publication
19433057 | J:151170
First Author: Feng HZ
Year: 2009
Journal: Arch Biochem Biophys
Title: Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation.
Volume: 487
Issue: 1
Pages: 36-41
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Publication
17526646 | J:126155
First Author: Liu J
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice.
Volume: 293
Issue: 2
Pages: H1273-81
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Publication
23810866 | J:308153
 
First Author: Li Y
Year: 2013
Journal: J Mol Cell Cardiol
Title: Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations.
Volume: 62
Pages: 227-36
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Publication
12923217 | J:133812
First Author: Pi Y
Year: 2003
Journal: J Physiol
Title: Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium.
Volume: 552
Issue: Pt 3
Pages: 845-57
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Publication
17540338 | J:122464
First Author: Opherk JP
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Cardiac-specific activation of Cre expression at late fetal development.
Volume: 359
Issue: 2
Pages: 209-13
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Publication
10642551 | J:59433
First Author: Murphy AM
Year: 2000
Journal: Science
Title: Transgenic mouse model of stunned myocardium.
Volume: 287
Issue: 5452
Pages: 488-91
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Publication
11356618 | J:69919
First Author: Kögler H
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Maintained contractile reserve in a transgenic mouse model of myocardial stunning.
Volume: 280
Issue: 6
Pages: H2623-30
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Publication
22940544 | J:198401
First Author: Henze M
Year: 2013
Journal: Biochim Biophys Acta
Title: New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I.
Volume: 1833
Issue: 4
Pages: 823-32
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Publication
18096573 | J:161911
First Author: Iorga B
Year: 2008
Journal: Cardiovasc Res
Title: Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.
Volume: 77
Issue: 4
Pages: 676-86
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Publication
22683325 | J:186721
First Author: Davis J
Year: 2012
Journal: J Mol Cell Cardiol
Title: Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy.
Volume: 53
Issue: 3
Pages: 446-57
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Publication
23352598 | J:206706
First Author: McKee LA
Year: 2013
Journal: Arch Biochem Biophys
Title: Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice.
Volume: 535
Issue: 1
Pages: 39-48
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Publication
15611140 | J:97072
First Author: Barbato JC
Year: 2005
Journal: J Biol Chem
Title: Proteolytic N-terminal truncation of cardiac troponin I enhances ventricular diastolic function.
Volume: 280
Issue: 8
Pages: 6602-9
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Publication
11158984 | J:68042
First Author: MacGowan GA
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Volume: 280
Issue: 2
Pages: H835-43
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Publication
8662015 | J:34377
First Author: Hastings KE
Year: 1996
Journal: J Mol Evol
Title: Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.
Volume: 42
Issue: 6
Pages: 631-40
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Publication
8661099 | J:33933
First Author: Bhavsar PK
Year: 1996
Journal: Genomics
Title: Isolation and characterization of the human cardiac troponin I gene (TNNI3).
Volume: 35
Issue: 1
Pages: 11-23
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Publication
9464252 | J:45503
First Author: Jin JP
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Developmentally regulated muscle type-specific alternative splicing of the COOH-terminal variable region of fast skeletal muscle troponin T and an aberrant splicing pathway to encode a mutant COOH-terminus.
Volume: 242
Issue: 3
Pages: 540-4
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Publication
16024565 | J:104781
First Author: Arteaga GM
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction.
Volume: 289
Issue: 5
Pages: H2183-92
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Publication
9241277 | J:113668
First Author: Kimura A
Year: 1997
Journal: Nat Genet
Title: Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.
Volume: 16
Issue: 4
Pages: 379-82
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Publication
12809519 | J:113932
First Author: Li Q
Year: 2003
Journal: Biochemistry
Title: Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
Volume: 42
Issue: 24
Pages: 7618-25
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Publication
12562915 | J:133820
First Author: Konhilas JP
Year: 2003
Journal: J Physiol
Title: Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing.
Volume: 547
Issue: Pt 3
Pages: 951-61
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Publication
17615373 | J:140293
First Author: Yasuda S
Year: 2007
Journal: Circ Res
Title: Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes.
Volume: 101
Issue: 4
Pages: 377-86
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Publication
19637843 | J:154873
First Author: Ayaz-Guner S
Year: 2009
Journal: Biochemistry
Title: In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated.
Volume: 48
Issue: 34
Pages: 8161-70
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Publication
21777381 | J:193010
First Author: Zhang Z
Year: 2011
Journal: FEBS J
Title: Calcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosin.
Volume: 278
Issue: 18
Pages: 3348-59
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Publication
24326031 | J:227880
 
First Author: Akhter S
Year: 2014
Journal: Arch Biochem Biophys
Title: Restrictive cardiomyopathy mutations demonstrate functions of the C-terminal end-segment of troponin I.
Volume: 552-553
Pages: 3-10
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Publication
15507454 | J:308286
First Author: Sakthivel S
Year: 2005
Journal: J Biol Chem
Title: In vivo and in vitro analysis of cardiac troponin I phosphorylation.
Volume: 280
Issue: 1
Pages: 703-14
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Publication
12181153 | J:311979
First Author: Pyle WG
Year: 2002
Journal: Am J Physiol Heart Circ Physiol
Title: Troponin I serines 43/45 and regulation of cardiac myofilament function.
Volume: 283
Issue: 3
Pages: H1215-24
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GXD Expression
GXD Expression
     
Probe: MGI:3054383
Assay Type: Northern blot
Annotation Date: 2004-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733128
Stage: TS28
Assay Id: MGI:3054398
Age: postnatal adult
Specimen Label: wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3054383
Assay Type: Northern blot
Annotation Date: 2004-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733128
Stage: TS28
Assay Id: MGI:3054398
Age: postnatal adult
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3656038
Assay Type: Western blot
Annotation Date: 2006-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3656039
Age: postnatal
Specimen Label: NTG
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3803187
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3803194
Age: embryonic day 18.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3803187
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3803194
Age: embryonic day 18.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6306071
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:6306115
Age: embryonic day 9.5
Image: S1f
Specimen Label: Ctrl
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6306071
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:6306115
Age: embryonic day 9.5
Image: S1f
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7561913
Assay Type: RT-PCR
Annotation Date: 2023-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:7561934
Age: embryonic day 14.5
Specimen Label: Wt non-diabetic
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7561913
Assay Type: RT-PCR
Annotation Date: 2023-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:7561934
Age: embryonic day 14.5
Specimen Label: +/- non-diabetic
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Specimen Label: DC25; Specimen C999
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Image: DC25; Specimen C999
Specimen Label: DC25; Specimen C999
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Image: DC25; Specimen C999
Specimen Label: DC25; Specimen C999
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7618945
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7618957
Age: embryonic day 12.5
Image: 1F cQKI WT
Specimen Label: 1F cQKI WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7618945
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7618957
Age: embryonic day 12.5
Image: 1F cQKI WT
Specimen Label: 1F cQKI WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7618945
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7618957
Age: embryonic day 12.5
Image: 1F cQKI KO
Specimen Label: 1F cQKI KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7618945
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7618957
Age: embryonic day 12.5
Image: 1F cQKI KO
Specimen Label: 1F cQKI KO
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Specimen Label: DC25; Specimen C999
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Image: DC25; Specimen C999
Specimen Label: DC25; Specimen C999
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Image: DC25; Specimen C999
Specimen Label: DC25; Specimen C999
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3821343
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1619822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421770
Age: embryonic day 14.5
Image: DC25; Specimen C999
Specimen Label: DC25; Specimen C999
Detected: true
Specimen Num: 1
•
•
•
•
•




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