| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
rabbit, European |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:225189 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-15 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:3825987 |
| Age: |
embryonic day 14.5 |
| Image: |
Additional file 4 Tnnt2 |
|
| Specimen Label: |
Additional file 4 Tnnt2 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7461647 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7466120 |
| Age: |
postnatal day 7 |
|
|
| Specimen Label: |
Tnnt2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
301
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu B |
| Year: |
2010 |
| Journal: |
Genesis |
| Title: |
Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse. |
| Volume: |
48 |
| Issue: |
1 |
| Pages: |
63-72 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733919 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
S4Cii TNNT2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733919 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
S4Cii TNNT2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733921 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
S4Eii TNNT2 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733921 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
S4Eii TNNT2 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733924 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
S4Gii TNNT2 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733924 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
S4Gii TNNT2 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
S4Ciii TNNT2 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
S4Ciii TNNT2 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734221 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
S4Eiii TNNT2 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734221 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
S4Eiii TNNT2 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734224 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
S4Giii TNNT2 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7470808 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1734224 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7470837 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
S4Giii TNNT2 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal week 8 |
| Image: |
1H |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1H |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal day 0 |
| Image: |
1-S2 P0 |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1-S2 P0 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal week 8 |
| Image: |
1-S2 Adult |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1-S2 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal day 0 |
| Image: |
1E |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal week 8 |
| Image: |
1H |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1H |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal day 0 |
| Image: |
1-S2 P0 |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1-S2 P0 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal week 8 |
| Image: |
1-S2 Adult |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1-S2 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7860806 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-02-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7860808 |
| Age: |
postnatal day 0 |
| Image: |
1E |
| Note: |
Tnnt2 is a cardiomyocyte marker. |
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 10.5 |
| Image: |
S4A Ctrl |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4A Ctrl |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 11.5 |
| Image: |
S4B Ctrl E11.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 12.5 |
| Image: |
S4B Ctrl E12.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 11.5 |
| Image: |
S4C Ctrl E11.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 12.5 |
| Image: |
S4C Ctrl E12.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 13.5 |
| Image: |
S4C Ctrl E13.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E13.5 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 10.5 |
| Image: |
S4A Ctrl |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4A Ctrl |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 11.5 |
| Image: |
S4B Ctrl E11.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 12.5 |
| Image: |
S4B Ctrl E12.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 11.5 |
| Image: |
S4C Ctrl E11.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 12.5 |
| Image: |
S4C Ctrl E12.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5588416 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7448838 |
| Age: |
embryonic day 13.5 |
| Image: |
S4C Ctrl E13.5 |
| Note: |
Co-expression of Tnnt2 and pHH3 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4C Ctrl E13.5 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Q |
| Year: |
2000 |
| Journal: |
Circ Res |
| Title: |
Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice. |
| Volume: |
86 |
| Issue: |
4 |
| Pages: |
478-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan J |
| Year: |
2015 |
| Journal: |
Genesis |
| Title: |
Generation of a tamoxifen inducible Tnnt2MerCreMer knock-in mouse model for cardiac studies. |
| Volume: |
53 |
| Issue: |
6 |
| Pages: |
377-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ahmad F |
| Year: |
2008 |
| Journal: |
PLoS One |
| Title: |
The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. |
| Volume: |
3 |
| Issue: |
7 |
| Pages: |
e2642 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Messer AE |
| Year: |
2016 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation. |
| Volume: |
601 |
|
| Pages: |
113-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haim TE |
| Year: |
2007 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Independent FHC-related cardiac troponin T mutations exhibit specific alterations in myocellular contractility and calcium kinetics. |
| Volume: |
42 |
| Issue: |
6 |
| Pages: |
1098-110 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu X |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells. |
| Volume: |
28 |
| Issue: |
5 |
| Pages: |
1346-1361.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lombardi R |
| Year: |
2008 |
| Journal: |
Cardiovasc Res |
| Title: |
Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies. |
| Volume: |
79 |
| Issue: |
1 |
| Pages: |
109-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bao D |
| Year: |
2015 |
| Journal: |
Dis Model Mech |
| Title: |
Tomoregulin-1 prevents cardiac hypertrophy after pressure overload in mice by inhibiting TAK1-JNK pathways. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
795-804 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sirenko SG |
| Year: |
2006 |
| Journal: |
J Physiol |
| Title: |
Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase. |
| Volume: |
575 |
| Issue: |
Pt 1 |
| Pages: |
201-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhan DY |
| Year: |
2009 |
| Journal: |
Cardiovasc Res |
| Title: |
Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. |
| Volume: |
84 |
| Issue: |
1 |
| Pages: |
64-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rice R |
| Year: |
2010 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Cardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts. |
| Volume: |
48 |
| Issue: |
5 |
| Pages: |
979-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maass AH |
| Year: |
2004 |
| Journal: |
Circulation |
| Title: |
Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. |
| Volume: |
110 |
| Issue: |
15 |
| Pages: |
2102-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ford SJ |
| Year: |
2012 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform. |
| Volume: |
53 |
| Issue: |
4 |
| Pages: |
542-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tardiff JC |
| Year: |
1998 |
| Journal: |
J Clin Invest |
| Title: |
A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. |
| Volume: |
101 |
| Issue: |
12 |
| Pages: |
2800-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ertz-Berger BR |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice. |
| Volume: |
102 |
| Issue: |
50 |
| Pages: |
18219-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guinto PJ |
| Year: |
2009 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models. |
| Volume: |
297 |
| Issue: |
2 |
| Pages: |
H614-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He H |
| Year: |
2007 |
| Journal: |
Biophys J |
| Title: |
R-92L and R-92W mutations in cardiac troponin T lead to distinct energetic phenotypes in intact mouse hearts. |
| Volume: |
93 |
| Issue: |
5 |
| Pages: |
1834-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miller T |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. |
| Volume: |
276 |
| Issue: |
6 |
| Pages: |
3743-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knollmann BC |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy. |
| Volume: |
276 |
| Issue: |
13 |
| Pages: |
10039-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dieseldorff Jones KM |
| Year: |
2019 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Pathogenic troponin T mutants with opposing effects on myofilament Ca2+ sensitivity attenuate cardiomyopathy phenotypes in mice. |
| Volume: |
661 |
|
| Pages: |
125-131 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ferrantini C |
| Year: |
2017 |
| Journal: |
J Am Heart Assoc |
| Title: |
Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models. |
| Volume: |
6 |
| Issue: |
7 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramratnam M |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. |
| Volume: |
11 |
| Issue: |
12 |
| Pages: |
e0167681 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Memo M |
| Year: |
2013 |
| Journal: |
Cardiovasc Res |
| Title: |
Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity. |
| Volume: |
99 |
| Issue: |
1 |
| Pages: |
65-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishii K |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo. |
| Volume: |
322 |
| Issue: |
1 |
| Pages: |
65-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chandra M |
| Year: |
2005 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation. |
| Volume: |
289 |
| Issue: |
5 |
| Pages: |
H2112-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan J |
| Year: |
2016 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
A series of robust genetic indicators for definitive identification of cardiomyocytes. |
| Volume: |
97 |
|
| Pages: |
278-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Han L |
| Year: |
2023 |
| Journal: |
Nat Cell Biol |
| Title: |
Lipid droplet-associated lncRNA LIPTER preserves cardiac lipid metabolism. |
| Volume: |
25 |
| Issue: |
7 |
| Pages: |
1033-1046 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujiwara K |
| Year: |
2024 |
| Journal: |
Cell Rep |
| Title: |
Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress. |
| Volume: |
43 |
| Issue: |
12 |
| Pages: |
115048 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chandra M |
| Year: |
2001 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T. |
| Volume: |
280 |
| Issue: |
2 |
| Pages: |
H705-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magadum A |
| Year: |
2020 |
| Journal: |
Circulation |
| Title: |
Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration. |
| Volume: |
141 |
| Issue: |
15 |
| Pages: |
1249-1265 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mifflin JJ |
| Year: |
2018 |
| Journal: |
Dev Dyn |
| Title: |
Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage. |
| Volume: |
247 |
| Issue: |
8 |
| Pages: |
1005-1017 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tardiff JC |
| Year: |
1999 |
| Journal: |
J Clin Invest |
| Title: |
Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. |
| Volume: |
104 |
| Issue: |
4 |
| Pages: |
469-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu X |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
5784 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farza H |
| Year: |
1999 |
| Journal: |
Mol Med Today |
| Title: |
Animal models of familial hypertrophic cardiomyopathy. |
| Volume: |
5 |
| Issue: |
12 |
| Pages: |
544-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu M |
| Year: |
2021 |
| Journal: |
Development |
| Title: |
The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. |
| Volume: |
148 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao K |
| Year: |
2022 |
| Journal: |
Development |
| Title: |
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. |
| Volume: |
149 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu H |
| Year: |
2024 |
| Journal: |
iScience |
| Title: |
Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. |
| Volume: |
27 |
| Issue: |
1 |
| Pages: |
108722 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sultana N |
| Year: |
2015 |
| Journal: |
Nat Commun |
| Title: |
Resident c-kit(+) cells in the heart are not cardiac stem cells. |
| Volume: |
6 |
|
| Pages: |
8701 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu P |
| Year: |
2023 |
| Journal: |
Dev Cell |
| Title: |
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. |
| Volume: |
58 |
| Issue: |
9 |
| Pages: |
791-805.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li Y |
| Year: |
2019 |
| Journal: |
Circ Res |
| Title: |
Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. |
| Volume: |
125 |
| Issue: |
3 |
| Pages: |
343-355 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|