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Search results 1 to 100 out of 615 for Tnnt2

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0.036s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wu B
Year: 2010
Journal: Genesis
Title: Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse.
Volume: 48
Issue: 1
Pages: 63-72
Publication
First Author: Yan J
Year: 2015
Journal: Genesis
Title: Generation of a tamoxifen inducible Tnnt2MerCreMer knock-in mouse model for cardiac studies.
Volume: 53
Issue: 6
Pages: 377-86
Publication
First Author: Mifflin JJ
Year: 2018
Journal: Dev Dyn
Title: Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.
Volume: 247
Issue: 8
Pages: 1005-1017
Publication  
First Author: Sultana N
Year: 2015
Journal: Nat Commun
Title: Resident c-kit(+) cells in the heart are not cardiac stem cells.
Volume: 6
Pages: 8701
Publication
First Author: Zhou B
Year: 2008
Journal: Nature
Title: Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart.
Volume: 454
Issue: 7200
Pages: 109-13
Publication
First Author: Ai S
Year: 2017
Journal: Circ Res
Title: Divergent Requirements for EZH1 in Heart Development Versus Regeneration.
Volume: 121
Issue: 2
Pages: 106-112
Publication
First Author: Huang ZP
Year: 2012
Journal: Circ Res
Title: CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy.
Volume: 110
Issue: 6
Pages: 818-30
Publication
First Author: Salguero-Jiménez A
Year: 2018
Journal: PLoS One
Title: Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function.
Volume: 13
Issue: 12
Pages: e0203100
Publication
First Author: Wu T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: HSPB7 is indispensable for heart development by modulating actin filament assembly.
Volume: 114
Issue: 45
Pages: 11956-11961
Publication
First Author: Hirai M
Year: 2017
Journal: J Clin Invest
Title: Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.
Volume: 127
Issue: 2
Pages: 569-582
Publication  
First Author: Liu X
Year: 2018
Journal: Sci Signal
Title: Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.
Volume: 11
Issue: 519
Publication
First Author: He A
Year: 2012
Journal: Circ Res
Title: Polycomb repressive complex 2 regulates normal development of the mouse heart.
Volume: 110
Issue: 3
Pages: 406-15
Publication
First Author: Peng Y
Year: 2014
Journal: Cardiovasc Res
Title: Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.
Volume: 103
Issue: 2
Pages: 258-67
Publication
First Author: Harmelink C
Year: 2013
Journal: Dev Biol
Title: Myocardial Mycn is essential for mouse ventricular wall morphogenesis.
Volume: 373
Issue: 1
Pages: 53-63
Publication    
First Author: Eley L
Year: 2018
Journal: Elife
Title: A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice.
Volume: 7
Publication
First Author: Song L
Year: 2007
Journal: Circ Res
Title: Myocardial smad4 is essential for cardiogenesis in mouse embryos.
Volume: 101
Issue: 3
Pages: 277-85
Publication
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
Publication
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
GXD Expression    
Probe: MGI:225189
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3825987
Age: embryonic day 14.5
Image: Additional file 4 Tnnt2
Detected: false
Specimen Num: 1
Gene
Type: gene
Organism: Homo sapiens
Protein
Organism: Mus musculus
Length: 301  
Fragment?: false
Allele
Name: troponin T2, cardiac; targeted mutation 1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Publication categories: ProxyCollection
Allele
Name: troponin T2, cardiac; targeted mutation 1.1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion 1, William T Pu
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
Publication categories: ProxyCollection
Publication
First Author: Yu W
Year: 2016
Journal: Development
Title: GATA4 regulates Fgf16 to promote heart repair after injury.
Volume: 143
Issue: 6
Pages: 936-49
Publication
First Author: Zhang D
Year: 2017
Journal: Nat Commun
Title: REST regulates the cell cycle for cardiac development and regeneration.
Volume: 8
Issue: 1
Pages: 1979
Publication
First Author: Han P
Year: 2014
Journal: Nature
Title: A long noncoding RNA protects the heart from pathological hypertrophy.
Volume: 514
Issue: 7520
Pages: 102-106
Publication
First Author: Zhang W
Year: 2016
Journal: Circulation
Title: Critical Roles of STAT3 in β-Adrenergic Functions in the Heart.
Volume: 133
Issue: 1
Pages: 48-61
Publication
First Author: Hubbi ME
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.
Volume: 111
Issue: 32
Pages: E3325-34
Publication
First Author: Han P
Year: 2016
Journal: Biochim Biophys Acta
Title: Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
Volume: 1863
Issue: 7 Pt B
Pages: 1772-81
Genotype
Symbol: Zfpm2/Zfpm2 Tg(Tnnt2-rtTA,tetO-cre)1Wtp/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Zhou B
Year: 2011
Journal: J Clin Invest
Title: Adult mouse epicardium modulates myocardial injury by secreting paracrine factors.
Volume: 121
Issue: 5
Pages: 1894-904
Publication
First Author: Hathaway CK
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade.
Volume: 112
Issue: 16
Pages: 5141-6
Publication
First Author: Hang CT
Year: 2010
Journal: Nature
Title: Chromatin regulation by Brg1 underlies heart muscle development and disease.
Volume: 466
Issue: 7302
Pages: 62-7
Publication
First Author: Zhou B
Year: 2009
Journal: J Clin Invest
Title: Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.
Volume: 119
Issue: 6
Pages: 1462-76
Publication
First Author: Wang Q
Year: 2000
Journal: Circ Res
Title: Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice.
Volume: 86
Issue: 4
Pages: 478-84
Publication
First Author: Chandra M
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation.
Volume: 289
Issue: 5
Pages: H2112-9
Publication
First Author: Haim TE
Year: 2007
Journal: J Mol Cell Cardiol
Title: Independent FHC-related cardiac troponin T mutations exhibit specific alterations in myocellular contractility and calcium kinetics.
Volume: 42
Issue: 6
Pages: 1098-110
Publication  
First Author: Messer AE
Year: 2016
Journal: Arch Biochem Biophys
Title: Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.
Volume: 601
Pages: 113-20
Publication
First Author: Chandra M
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T.
Volume: 280
Issue: 2
Pages: H705-13
Publication
First Author: Tardiff JC
Year: 1999
Journal: J Clin Invest
Title: Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.
Volume: 104
Issue: 4
Pages: 469-81
Publication
First Author: Huang ZP
Year: 2015
Journal: J Clin Invest
Title: Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.
Volume: 125
Issue: 11
Pages: 4122-34
Publication
First Author: Cheng H
Year: 2010
Journal: Circ Res
Title: Loss of enigma homolog protein results in dilated cardiomyopathy.
Volume: 107
Issue: 3
Pages: 348-56
Publication
First Author: Morikawa Y
Year: 2008
Journal: Circ Res
Title: Cardiac neural crest expression of Hand2 regulates outflow and second heart field development.
Volume: 103
Issue: 12
Pages: 1422-9
Publication
First Author: Jiao K
Year: 2006
Journal: Development
Title: Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development.
Volume: 133
Issue: 22
Pages: 4585-93
Publication
First Author: Luxán G
Year: 2013
Journal: Nat Med
Title: Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.
Volume: 19
Issue: 2
Pages: 193-201
Publication
First Author: Ilagan R
Year: 2006
Journal: Development
Title: Fgf8 is required for anterior heart field development.
Volume: 133
Issue: 12
Pages: 2435-45
Publication
First Author: Liang X
Year: 2015
Journal: J Clin Invest
Title: Transcription factor ISL1 is essential for pacemaker development and function.
Volume: 125
Issue: 8
Pages: 3256-68
Publication
First Author: Goddeeris MM
Year: 2008
Journal: Development
Title: Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart.
Volume: 135
Issue: 10
Pages: 1887-95
Publication
First Author: Goddeeris MM
Year: 2007
Journal: Development
Title: Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.
Volume: 134
Issue: 8
Pages: 1593-604
Publication
First Author: Jiao K
Year: 2003
Journal: Genes Dev
Title: An essential role of Bmp4 in the atrioventricular septation of the mouse heart.
Volume: 17
Issue: 19
Pages: 2362-7
Publication
First Author: Wu B
Year: 2012
Journal: Cell
Title: Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.
Volume: 151
Issue: 5
Pages: 1083-96
Publication
First Author: Ammirabile G
Year: 2012
Journal: Cardiovasc Res
Title: Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium.
Volume: 93
Issue: 2
Pages: 291-301
Publication
First Author: Zhou L
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation.
Volume: 114
Issue: 8
Pages: E1422-E1431
Publication
First Author: Horsthemke M
Year: 2019
Journal: J Biol Chem
Title: A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.
Volume: 294
Issue: 18
Pages: 7202-7218
Publication
First Author: Mohamed TMA
Year: 2018
Journal: Cell
Title: Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration.
Volume: 173
Issue: 1
Pages: 104-116.e12
Publication
First Author: Chen H
Year: 2013
Journal: Development
Title: Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity.
Volume: 140
Issue: 9
Pages: 1946-57
Publication
First Author: van Vliet PP
Year: 2017
Journal: Dev Biol
Title: Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.
Volume: 429
Issue: 1
Pages: 249-259
Publication
First Author: Luna-Zurita L
Year: 2010
Journal: J Clin Invest
Title: Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.
Volume: 120
Issue: 10
Pages: 3493-507
Publication
First Author: von Gise A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy.
Volume: 109
Issue: 7
Pages: 2394-9
Publication
First Author: Ang SY
Year: 2016
Journal: Development
Title: KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.
Volume: 143
Issue: 5
Pages: 810-21
Publication
First Author: Zhang H
Year: 2016
Journal: Circ Res
Title: Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.
Volume: 118
Issue: 12
Pages: 1880-93
Publication
First Author: Santos R
Year: 2016
Journal: PLoS Biol
Title: Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.
Volume: 14
Issue: 9
Pages: e2000197
Publication
First Author: Liang D
Year: 2014
Journal: Dev Biol
Title: Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis.
Volume: 395
Issue: 2
Pages: 232-44
Publication
First Author: Ounzain S
Year: 2012
Journal: Mol Cell Biol
Title: Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4.
Volume: 32
Issue: 10
Pages: 1830-43
Publication
First Author: Wang Y
Year: 2017
Journal: Nat Commun
Title: Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.
Volume: 8
Issue: 1
Pages: 578
Publication  
First Author: Wang Y
Year: 2018
Journal: J Mol Cell Cardiol
Title: NOTCH maintains developmental cardiac gene network through WNT5A.
Volume: 125
Pages: 98-105
Publication  
First Author: Yin JC
Year: 2017
Journal: Nat Commun
Title: Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.
Volume: 8
Pages: 15518
Publication
First Author: Liang X
Year: 2009
Journal: Circulation
Title: Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.
Volume: 120
Issue: 7
Pages: 568-76
Publication
First Author: Ding J
Year: 2015
Journal: Nat Genet
Title: Trbp regulates heart function through microRNA-mediated Sox6 repression.
Volume: 47
Issue: 7
Pages: 776-83
Publication
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
Publication
First Author: Manso AM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.
Volume: 114
Issue: 30
Pages: E6250-E6259
Publication
First Author: Dees E
Year: 2012
Journal: Dis Model Mech
Title: Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Volume: 5
Issue: 4
Pages: 468-80
Publication
First Author: Manalo A
Year: 2018
Journal: Sci Rep
Title: Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.
Volume: 8
Issue: 1
Pages: 7546
Publication  
First Author: Wang Y
Year: 2018
Journal: J Mol Cell Cardiol
Title: Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.
Volume: 123
Pages: 150-158
Publication
First Author: Zhang D
Year: 2017
Journal: Nucleic Acids Res
Title: Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Volume: 45
Issue: 6
Pages: 3102-3115
Publication
First Author: Wilczewski CM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: CHD4 and the NuRD complex directly control cardiac sarcomere formation.
Volume: 115
Issue: 26
Pages: 6727-6732
Publication
First Author: Chen JW
Year: 2006
Journal: Circ Res
Title: Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves.
Volume: 98
Issue: 7
Pages: 923-30
Publication
First Author: Maillet M
Year: 2010
Journal: J Biol Chem
Title: Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.
Volume: 285
Issue: 9
Pages: 6716-24
Publication
First Author: Lin Z
Year: 2015
Journal: Circ Res
Title: Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival.
Volume: 116
Issue: 1
Pages: 35-45
Allele
Name: transgene insertion 5, Brigid L Hogan
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Cho E
Year: 2018
Journal: J Biol Chem
Title: Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.
Volume: 293
Issue: 30
Pages: 11659-11673
Publication
First Author: Sun Q
Year: 2019
Journal: Dev Biol
Title: SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.
Volume: 452
Issue: 1
Pages: 1-7
Publication
First Author: Hirai M
Year: 2016
Journal: Circ Res
Title: Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation.
Volume: 118
Issue: 1
Pages: 20-8
Publication
First Author: Lauriol J
Year: 2016
Journal: J Clin Invest
Title: Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.
Volume: 126
Issue: 8
Pages: 2989-3005
Genotype
Symbol: Cxadr/Cxadr Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cxadr/Cxadr Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmp4/Bmp4 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S/Sv * Black Swiss * C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmp4/Bmp4 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hand2/Hand2<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lims1/Lims1 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lims1/Lims1 Lims2/Lims2 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pdlim5/Pdlim5 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cenpf/Cenpf Tg(Tnnt2-cre)5Blh/?
Background: involves: C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Vegfa/Vegfa Tg(Tnnt2-cre)5Blh/?
Background: involves: 129/Sv * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true