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Search results 1 to 100 out of 274 for Tnr

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0.048s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Tenascin-R (TNR) is an extracellular matrix glycoprotein that is expressed primarily in the central nervous system. It regulates neurogenesis and affects cell migration, adhesion and differentiation [, ].Tenascins are extracellular matrix glycoproteins that act both as integrin ligands and as modifiers of fibronectin-integrin interactions toregulate cell adhesion, migration, proliferation and differentiation. Tenascins are usually composed of repeated epidermal growth factor (EGF)-like domains, fibronectin-type III (FNIII) domains and a C-terminal fibrinogen related domain (FReD) [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Xu JC
Year: 2014
Journal: J Cell Sci
Title: The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice.
Volume: 127
Issue: Pt 3
Pages: 641-52
Gene
Type: gene
Organism: human
Publication
First Author: Arrigo G
Year: 1997
Journal: Cytogenet Cell Genet
Title: Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24.
Volume: 78
Issue: 2
Pages: 145-6
Protein
Organism: Mus musculus/domesticus
Length: 1358  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
Publication
First Author: Adams JC
Year: 2015
Journal: Cell Adh Migr
Title: The evolution of tenascins and fibronectin.
Volume: 9
Issue: 1-2
Pages: 22-33
Publication
First Author: Anlar B
Year: 2012
Journal: Int J Biochem Cell Biol
Title: Tenascin-R: role in the central nervous system.
Volume: 44
Issue: 9
Pages: 1385-9
Publication
First Author: Newkirk SJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Intact piRNA pathway prevents L1 mobilization in male meiosis.
Volume: 114
Issue: 28
Pages: E5635-E5644
Publication
First Author: Hoffmann K
Year: 2009
Journal: Epilepsia
Title: Retarded kindling progression in mice deficient in the extracellular matrix glycoprotein tenascin-R.
Volume: 50
Issue: 4
Pages: 859-69
Publication
First Author: Apostolova I
Year: 2006
Journal: J Neurosci
Title: Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice.
Volume: 26
Issue: 30
Pages: 7849-59
Publication
First Author: David LS
Year: 2013
Journal: J Neurosci
Title: The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb.
Volume: 33
Issue: 25
Pages: 10324-39
Publication
First Author: Morellini F
Year: 2010
Journal: Cereb Cortex
Title: Improved reversal learning and working memory and enhanced reactivity to novelty in mice with enhanced GABAergic innervation in the dentate gyrus.
Volume: 20
Issue: 11
Pages: 2712-27
Publication
First Author: Bukalo O
Year: 2007
Journal: J Neurosci
Title: Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R.
Volume: 27
Issue: 22
Pages: 6019-28
Publication
First Author: Meier ID
Year: 2010
Journal: FASEB J
Title: Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.
Volume: 24
Issue: 6
Pages: 1714-24
Publication
First Author: Guntinas-Lichius O
Year: 2005
Journal: Eur J Neurosci
Title: Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair.
Volume: 22
Issue: 9
Pages: 2171-9
Publication
First Author: Czopka T
Year: 2009
Journal: Glia
Title: Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway.
Volume: 57
Issue: 16
Pages: 1790-801
Publication
First Author: Okuda H
Year: 2014
Journal: J Biol Chem
Title: Chondroitin sulfate proteoglycan tenascin-R regulates glutamate uptake by adult brain astrocytes.
Volume: 289
Issue: 5
Pages: 2620-31
Publication  
First Author: Tan K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: The Rhox gene cluster suppresses germline LINE1 transposition.
Volume: 118
Issue: 23
Publication
First Author: Guan Y
Year: 2023
Journal: PLoS Genet
Title: The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice.
Volume: 19
Issue: 5
Pages: e1010566
Publication  
First Author: Bauch J
Year: 2022
Journal: Cells
Title: The Extracellular Matrix Proteins Tenascin-C and Tenascin-R Retard Oligodendrocyte Precursor Maturation and Myelin Regeneration in a Cuprizone-Induced Long-Term Demyelination Animal Model.
Volume: 11
Issue: 11
Publication  
First Author: Ashbrook DG
Year: 2015
Journal: Front Behav Neurosci
Title: A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder.
Volume: 9
Pages: 171
Publication      
First Author: Bona N
Year: 2023
Journal: Nat Struct Mol Biol
Title: Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Weber P
Year: 1999
Journal: J Neurosci
Title: Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.
Volume: 19
Issue: 11
Pages: 4245-62
Publication
First Author: Pesheva P
Year: 1989
Journal: J Cell Biol
Title: J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion.
Volume: 109
Issue: 4 Pt 1
Pages: 1765-78
Publication
First Author: Pesheva P
Year: 1997
Journal: J Neurosci
Title: Tenascin-R is an intrinsic autocrine factor for oligodendrocyte differentiation and promotes cell adhesion by a sulfatide-mediated mechanism.
Volume: 17
Issue: 12
Pages: 4642-51
Publication
First Author: Gurevicius K
Year: 2004
Journal: Mol Cell Neurosci
Title: Enhanced cortical and hippocampal neuronal excitability in mice deficient in the extracellular matrix glycoprotein tenascin-R.
Volume: 25
Issue: 3
Pages: 515-23
Publication
First Author: Saghatelyan AK
Year: 2001
Journal: Mol Cell Neurosci
Title: Reduced perisomatic inhibition, increased excitatory transmission, and impaired long-term potentiation in mice deficient for the extracellular matrix glycoprotein tenascin-R.
Volume: 17
Issue: 1
Pages: 226-40
Publication
First Author: Freitag S
Year: 2003
Journal: Behav Brain Res
Title: Behavioral alterations in mice deficient for the extracellular matrix glycoprotein tenascin-R.
Volume: 145
Issue: 1-2
Pages: 189-207
Publication
First Author: Brückner G
Year: 2000
Journal: J Comp Neurol
Title: Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R.
Volume: 428
Issue: 4
Pages: 616-29
Publication
First Author: Montag-Sallaz M
Year: 2003
Journal: Genes Brain Behav
Title: Severe cognitive and motor coordination deficits in tenascin-R-deficient mice.
Volume: 2
Issue: 1
Pages: 20-31
Publication
First Author: Bukalo O
Year: 2001
Journal: Neuroscience
Title: Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus.
Volume: 104
Issue: 2
Pages: 359-69
Publication
First Author: Saghatelyan A
Year: 2004
Journal: Nat Neurosci
Title: Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain.
Volume: 7
Issue: 4
Pages: 347-56
Publication
First Author: Nikonenko A
Year: 2003
Journal: J Comp Neurol
Title: Tenascin-R-deficient mice show structural alterations of symmetric perisomatic synapses in the CA1 region of the hippocampus.
Volume: 456
Issue: 4
Pages: 338-49
Publication
First Author: Brenneke F
Year: 2004
Journal: Neuroscience
Title: Mice deficient for the extracellular matrix glycoprotein tenascin-r show physiological and structural hallmarks of increased hippocampal excitability, but no increased susceptibility to seizures in the pilocarpine model of epilepsy.
Volume: 124
Issue: 4
Pages: 841-55
Publication
First Author: Bartsch U
Year: 1993
Journal: Glia
Title: Expression of janusin (J1-160/180) in the retina and optic nerve of the developing and adult mouse.
Volume: 9
Issue: 1
Pages: 57-69
Publication
First Author: Pesheva P
Year: 2006
Journal: Mol Cell Neurosci
Title: Early coevolution of adhesive but not antiadhesive tenascin-R ligand-receptor pairs in vertebrates: a phylogenetic study.
Volume: 32
Issue: 4
Pages: 366-86
Publication
First Author: Xiao ZC
Year: 1997
Journal: J Biol Chem
Title: Isolation of a tenascin-R binding protein from mouse brain membranes. A phosphacan-related chondroitin sulfate proteoglycan.
Volume: 272
Issue: 51
Pages: 32092-101
Publication  
First Author: Pesheva P
Year: 1994
Journal: J Cell Sci
Title: Tenascin-R (J1 160/180 inhibits fibronectin-mediated cell adhesion--functional relatedness to tenascin-C.
Volume: 107 ( Pt 8)
Pages: 2323-33
Publication
First Author: Schachner M
Year: 1994
Journal: Perspect Dev Neurobiol
Title: The perplexing multifunctionality of janusin, a tenascin-related molecule.
Volume: 2
Issue: 1
Pages: 33-41
Publication
First Author: Putthoff P
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Structure of the murine tenascin-R gene and functional characterisation of the promoter.
Volume: 308
Issue: 4
Pages: 940-9
Publication
First Author: Wintergerst ES
Year: 1993
Journal: Eur J Neurosci
Title: Localization of janusin mRNA in the central nervous system of the developing and adult mouse.
Volume: 5
Issue: 4
Pages: 299-310
GXD Expression      
Probe: MGI:6752580
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753207
Age: embryonic day 12.5
Specimen Label: PA1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6752580
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753209
Age: embryonic day 12.5
Specimen Label: PA2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_05
Specimen Label: euxassay_012507_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_06
Specimen Label: euxassay_012507_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_07
Specimen Label: euxassay_012507_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_08
Specimen Label: euxassay_012507_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_09
Specimen Label: euxassay_012507_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_10
Specimen Label: euxassay_012507_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_11
Specimen Label: euxassay_012507_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_12
Specimen Label: euxassay_012507_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_13
Specimen Label: euxassay_012507_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_14
Specimen Label: euxassay_012507_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_15
Specimen Label: euxassay_012507_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_16
Specimen Label: euxassay_012507_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_17
Specimen Label: euxassay_012507_17
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:10997
Specimen Label: GUDMAP:10997
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:11011
Specimen Label: GUDMAP:11011
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:10997
Specimen Label: GUDMAP:10997
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:11011
Specimen Label: GUDMAP:11011
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:10997
Specimen Label: GUDMAP:10997
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:10997
Specimen Label: GUDMAP:10997
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5002111
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542665
Age: embryonic day 15.5
Image: GUDMAP:11011
Specimen Label: GUDMAP:11011
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3839381
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3576028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3839531
Age: postnatal day 8
Image: 6I
Note: Reduced expression in the region of the atrioventricular and semilunar valves.
Specimen Label: 6I
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_10
Specimen Label: euxassay_012507_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_11
Specimen Label: euxassay_012507_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_12
Specimen Label: euxassay_012507_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_15
Specimen Label: euxassay_012507_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_16
Specimen Label: euxassay_012507_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4424952
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828862
Age: embryonic day 14.5
Image: euxassay_012507_17
Specimen Label: euxassay_012507_17
Detected: true
Specimen Num: 17