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Search results 1 to 100 out of 108 for Tnrc6c

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Mammals have three GW182 paralogues, TNRC6A, TNRC6B and TNRC6C. They interact directly with Argonaute (Ago) proteins and function downstream as effectors mediating mRNA repression. They repress mRNAs by recruiting the CCR4-NOT complex to the mRNA. They contain the N-terminal effector domain (NED), the middle Q-rich region, and the C-terminal effector domain (CED) containing the poly(A) binding protein (PABP)-interacting motif 2 (PAM2) and the RNA-recognition motif (RRM) [].This entry represents TNRC6C from vertebrates. Similar to TNRC6A/B, TNRC6C is essential for efficient miRNA repression [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zipprich JT
Year: 2009
Journal: RNA
Title: Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.
Volume: 15
Issue: 5
Pages: 781-93
Protein
Organism: Mus musculus/domesticus
Length: 1690  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1732  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1900  
Fragment?: false
Publication
First Author: Chekulaeva M
Year: 2011
Journal: Nat Struct Mol Biol
Title: miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.
Volume: 18
Issue: 11
Pages: 1218-26
Publication
First Author: Chen CY
Year: 2009
Journal: Nat Struct Mol Biol
Title: Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.
Volume: 16
Issue: 11
Pages: 1160-6
Publication
First Author: Guo H
Year: 2017
Journal: Dev Biol
Title: Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.
Volume: 430
Issue: 1
Pages: 214-223
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3614673
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616491
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3614673
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616491
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: TNRC6c-/-
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: TNRC6c-/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:7257870
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7258048
Age: postnatal day 0
Image: 1
Specimen Label: TNRC6c-/-
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7257879
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:7258060
Age: embryonic day 17.5
Image: 4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7257879
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:7258060
Age: embryonic day 17.5
Image: 4
Specimen Label: KO
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7257879
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7258072
Age: embryonic day 18.5
Image: 4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7257879
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7258072
Age: embryonic day 18.5
Image: 4
Specimen Label: KO
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Note: Expression was detected in precortical tissue.
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617765
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1697427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression    
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615480
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3617765
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4427296
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540602
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4427296
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540602
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4427296
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540602
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Jiang Z
Year: 2012
Journal: J Biol Chem
Title: Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.
Volume: 287
Issue: 8
Pages: 5979-87
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication  
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations