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Search results 1 to 100 out of 123 for Top1

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0.04s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression    
Probe: MGI:4354565
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354861
Age: embryonic day 14.5
Image: 3D & Table S5 - Top1
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:4354565
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4354861
Age: embryonic day 14.5
Image: 3D & Table S5 - Top1
Note: Expression is present in the upper, but not the lower, cortical plate.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4354565
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354861
Age: embryonic day 14.5
Image: 3D & Table S5 - Top1
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Smith SF
Year: 2001
Journal: Gene
Title: Characterisation of two topoisomerase 1 genes in the pufferfish (Fugu rubripes).
Volume: 265
Issue: 1-2
Pages: 195-204
Publication
First Author: Mabb AM
Year: 2016
Journal: PLoS One
Title: Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.
Volume: 11
Issue: 5
Pages: e0156439
Publication
First Author: Mabb AM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Topoisomerase 1 inhibition reversibly impairs synaptic function.
Volume: 111
Issue: 48
Pages: 17290-5
Publication
First Author: Kobayashi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.
Volume: 108
Issue: 48
Pages: 19305-10
Publication
First Author: Dalla Rosa I
Year: 2014
Journal: J Biol Chem
Title: Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt).
Volume: 289
Issue: 26
Pages: 18595-602
Publication  
First Author: Rettenberger G
Year: 1991
Journal: Cytogenet Cell Genet
Title: Localization of the type I DNA topoisomerase gene in man and mouse
Volume: 58
Pages: 2032 (Abstr.)
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Publication
First Author: Fragola G
Year: 2020
Journal: Nat Commun
Title: Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration.
Volume: 11
Issue: 1
Pages: 1962
Publication
First Author: Lin CP
Year: 2008
Journal: J Biol Chem
Title: A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.
Volume: 283
Issue: 30
Pages: 21074-83
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Baumgärtner B
Year: 1994
Journal: Biochim Biophys Acta
Title: Conserved regulatory elements in the type I DNA topoisomerase gene promoters of mouse and man.
Volume: 1218
Issue: 1
Pages: 123-7
Publication
First Author: Baumgärtner B
Year: 1994
Journal: Mamm Genome
Title: Mouse genes encoding DNA topoisomerase I.
Volume: 5
Issue: 1
Pages: 19-25
Publication
First Author: Morham SG
Year: 1996
Journal: Mol Cell Biol
Title: Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.
Volume: 16
Issue: 12
Pages: 6804-9
Publication
First Author: Plaschkes I
Year: 2005
Journal: J Comp Neurol
Title: DNA topoisomerase I in the mouse central nervous system: Age and sex dependence.
Volume: 493
Issue: 3
Pages: 357-69
Publication
First Author: Mo YY
Year: 2000
Journal: J Biol Chem
Title: A novel nuclear localization signal in human DNA topoisomerase I.
Volume: 275
Issue: 52
Pages: 41107-13
GXD Expression      
Probe: MGI:5699734
Assay Type: Northern blot
Annotation Date: 2015-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:5699735
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5699734
Assay Type: Northern blot
Annotation Date: 2015-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:5699735
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191495
Age: embryonic day 11.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191495
Age: embryonic day 13.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191495
Age: embryonic day 15.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191495
Age: embryonic day 18.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191495
Age: postnatal day 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191495
Age: postnatal day 14
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191495
Age: postnatal day 28
Detected: true
Specimen Num: 7
Publication
First Author: Katyal S
Year: 2014
Journal: Nat Neurosci
Title: Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Volume: 17
Issue: 6
Pages: 813-21
Publication
First Author: Khiati S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
Volume: 112
Issue: 36
Pages: 11282-7
Publication
First Author: Douarre C
Year: 2012
Journal: PLoS One
Title: Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.
Volume: 7
Issue: 7
Pages: e41094
Publication
First Author: Cobb J
Year: 1997
Journal: Mol Reprod Dev
Title: Analysis of expression and function of topoisomerase I and II during meiosis in male mice.
Volume: 46
Issue: 4
Pages: 489-98
Publication
First Author: Ho JSY
Year: 2021
Journal: Cell
Title: TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
Volume: 184
Issue: 10
Pages: 2618-2632.e17
Publication
First Author: Maskey RS
Year: 2017
Journal: Nucleic Acids Res
Title: Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.
Volume: 45
Issue: 8
Pages: 4564-4576
Publication
First Author: Liddell RA
Year: 1994
Journal: Mouse Genome
Title: Chromosomal localization and evolution of topoisomerase I sequences in the Mus genome
Volume: 92
Issue: 3
Pages: 520-22
Publication
First Author: Grillot DA
Year: 1997
Journal: J Immunol
Title: Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.
Volume: 158
Issue: 10
Pages: 4750-7
Publication
First Author: Nanda N
Year: 1999
Journal: Arch Biochem Biophys
Title: Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2).
Volume: 366
Issue: 1
Pages: 151-6
Publication
First Author: Shekhar S
Year: 2017
Journal: Hum Mol Genet
Title: Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.
Volume: 26
Issue: 2
Pages: 420-429
Publication
First Author: Lebel M
Year: 2002
Journal: Carcinogenesis
Title: Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
Volume: 23
Issue: 1
Pages: 213-6
Publication
First Author: Baloch Z
Year: 1995
Journal: Cell Immunol
Title: Modulation of topoisomerase activities by tumor necrosis factor.
Volume: 160
Issue: 1
Pages: 98-103
Publication
First Author: Porteus MH
Year: 1992
Journal: Brain Res Mol Brain Res
Title: Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon.
Volume: 12
Issue: 1-3
Pages: 7-22
Publication
First Author: Koiwai O
Year: 1993
Journal: Gene
Title: Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene.
Volume: 125
Issue: 2
Pages: 211-6
Publication
First Author: Leco KJ
Year: 1997
Journal: Dev Genet
Title: Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse.
Volume: 21
Issue: 1
Pages: 55-60
Publication
First Author: Verlaet M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genetic imbalances in preleukemic thymuses.
Volume: 283
Issue: 1
Pages: 12-8
Publication
First Author: Kingsmore SF
Year: 1994
Journal: Mamm Genome
Title: Genetic mapping of DNA topoisomerase I-related sequences to mouse chromosomes 2 and 14.
Volume: 5
Issue: 4
Pages: 247-8
Publication
First Author: Masaki S
Year: 1994
Journal: Genomics
Title: The gene Bfsp1 for the lens fiber cell beaded-filament structural protein CP94 maps to mouse chromosome 2.
Volume: 22
Issue: 2
Pages: 449-50
Protein
Organism: Mus musculus
Length: 107  
Fragment?: true
Publication
First Author: Gowher H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.
Volume: 109
Issue: 7
Pages: 2370-5
Publication
First Author: Giros B
Year: 1995
Journal: Life Sci
Title: Chromosomal localization of opioid peptide and receptor genes in the mouse.
Volume: 56
Issue: 18
Pages: PL369-75
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62