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Search results 1 to 100 out of 330 for Tor1a

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Type Details Score
Gene
1861 | TOR1A
Type: gene
Organism: human
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Gene
533699 | TOR1A
Type: gene
Organism: cattle
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Gene
417190 | TOR1A
Type: gene
Organism: chicken
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Gene
722520 | TOR1A
Type: gene
Organism: macaque, rhesus
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Gene
548991 | tor1a
Type: gene
Organism: frog, western clawed
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Gene
491296 | TOR1A
Type: gene
Organism: dog, domestic
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Gene
742691 | TOR1A
Type: gene
Organism: chimpanzee
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Gene
266606 | Tor1a
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1353568 | Tor1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10644435 | J:60248
First Author: Ozelius LJ
Year: 1999
Journal: Genomics
Title: The TOR1A (DYT1) gene family and its role in early onset torsion dystonia.
Volume: 62
Issue: 3
Pages: 377-84
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Publication
33894367 | J:343852
 
First Author: Downs AM
Year: 2021
Journal: Neurobiol Dis
Title: Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia.
Volume: 155
Pages: 105369
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Publication
29868845 | J:263180
First Author: Dominguez Gonzalez B
Year: 2018
Journal: Hum Mol Genet
Title: Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease.
Volume: 27
Issue: 12
Pages: 2154-2170
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Publication
35314320 | J:328520
 
First Author: Downs AM
Year: 2022
Journal: Neurobiol Dis
Title: Blockade of M4 muscarinic receptors on striatal cholinergic interneurons normalizes striatal dopamine release in a mouse model of TOR1A dystonia.
Volume: 168
Pages: 105699
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Publication
27168150 | J:247570
 
First Author: Bhagat SL
Year: 2016
Journal: Neurobiol Dis
Title: Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models.
Volume: 93
Pages: 137-45
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Publication
12007841 | J:76913
First Author: Ziefer P
Year: 2002
Journal: Brain Res Mol Brain Res
Title: Molecular cloning and expression of rat torsinA in the normal and genetically dystonic (dt) rat.
Volume: 101
Issue: 1-2
Pages: 132-5
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Publication
16242683 | J:104513
First Author: Dang MT
Year: 2005
Journal: Exp Neurol
Title: Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystonia.
Volume: 196
Issue: 2
Pages: 452-63
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Publication
17046090 | J:131080
First Author: Dang MT
Year: 2006
Journal: Neurosci Res
Title: Motor deficits and hyperactivity in Dyt1 knockdown mice.
Volume: 56
Issue: 4
Pages: 470-4
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Publication
24121114 | J:201962
 
First Author: Song CH
Year: 2014
Journal: Neurobiol Dis
Title: Subtle microstructural changes of the cerebellum in a knock-in mouse model of DYT1 dystonia.
Volume: 62
Pages: 372-80
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Publication
21464304 | J:171370
First Author: Uluğ AM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice.
Volume: 108
Issue: 16
Pages: 6638-43
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Publication
22393392 | J:185289
First Author: Tanabe LM
Year: 2012
Journal: PLoS One
Title: Genetic background modulates the phenotype of a mouse model of DYT1 dystonia.
Volume: 7
Issue: 2
Pages: e32245
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Publication
29396398 | J:263071
First Author: György B
Year: 2018
Journal: Sci Rep
Title: Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts.
Volume: 8
Issue: 1
Pages: 2324
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Publication
25447231 | J:259758
 
First Author: Vo A
Year: 2015
Journal: Neurobiol Dis
Title: 18FDG-microPET and MR DTI findings in Tor1a+/- heterozygous knock-out mice.
Volume: 73
Pages: 399-406
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Publication
36417958 | J:334382
 
First Author: Berryman D
Year: 2023
Journal: Behav Brain Res
Title: Motor deficit and lack of overt dystonia in Dlx conditional Dyt1 knockout mice.
Volume: 439
Pages: 114221
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Publication
33529159 | J:307028
 
First Author: Li J
Year: 2021
Journal: J Clin Invest
Title: TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia.
Volume: 131
Issue: 6
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Publication
27769743 | J:242639
 
First Author: Richter F
Year: 2017
Journal: Behav Brain Res
Title: Sensorimotor tests unmask a phenotype in the DYT1 knock-in mouse model of dystonia.
Volume: 317
Pages: 536-541
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Publication
31805123 | J:282565
First Author: Richter F
Year: 2019
Journal: PLoS One
Title: Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia.
Volume: 14
Issue: 12
Pages: e0226080
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Publication
22579992 | J:329741
First Author: Sciamanna G
Year: 2012
Journal: Neurobiol Dis
Title: Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA.
Volume: 47
Issue: 3
Pages: 416-27
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Publication
32202496 | J:288753
   
First Author: Li J
Year: 2020
Journal: Elife
Title: TorsinB overexpression prevents abnormal twisting in DYT1 dystonia mouse models.
Volume: 9
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Publication
24260480 | J:209674
First Author: Iwabuchi S
Year: 2013
Journal: PLoS One
Title: Minimal Change in the cytoplasmic calcium dynamics in striatal GABAergic neurons of a DYT1 dystonia knock-in mouse model.
Volume: 8
Issue: 11
Pages: e80793
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Publication
30403723 | J:267986
First Author: Mitchell SB
Year: 2018
Journal: PLoS One
Title: Structure of the Golgi apparatus is not influenced by a GAG deletion mutation in the dystonia-associated gene Tor1a.
Volume: 13
Issue: 11
Pages: e0206123
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Publication
22880064 | J:189823
First Author: Bode N
Year: 2012
Journal: PLoS One
Title: DYT1 knock-in mice are not sensitized against mitochondrial complex-II inhibition.
Volume: 7
Issue: 8
Pages: e42644
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Publication
23336980 | J:197748
 
First Author: Song CH
Year: 2013
Journal: Neurobiol Dis
Title: Subtle microstructural changes of the striatum in a DYT1 knock-in mouse model of dystonia.
Volume: 54
Pages: 362-71
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Publication
27716431 | J:319199
First Author: Ip CW
Year: 2016
Journal: Acta Neuropathol Commun
Title: Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury.
Volume: 4
Issue: 1
Pages: 108
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Publication
37134150 | J:340335
First Author: Pocratsky AM
Year: 2023
Journal: Sci Transl Med
Title: Pathophysiology of Dyt1-Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction.
Volume: 15
Issue: 694
Pages: eadg3904
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Publication
32041188 | J:297757
 
First Author: D'Angelo V
Year: 2020
Journal: Int J Mol Sci
Title: Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model.
Volume: 21
Issue: 3
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Publication
29045835 | J:255264
First Author: Zhang J
Year: 2017
Journal: Cell Rep
Title: A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry.
Volume: 21
Issue: 3
Pages: 666-678
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Publication
20015956 | J:157110
First Author: Jungwirth M
Year: 2010
Journal: Hum Mol Genet
Title: Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Volume: 19
Issue: 5
Pages: 888-900
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Publication
26370418 | J:225567
First Author: Weisheit CE
Year: 2015
Journal: Hum Mol Genet
Title: A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation.
Volume: 24
Issue: 22
Pages: 6459-72
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Publication
24937429 | J:213785
First Author: Liang CC
Year: 2014
Journal: J Clin Invest
Title: TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration.
Volume: 124
Issue: 7
Pages: 3080-92
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Publication
33476687 | J:307041
 
First Author: Liu Y
Year: 2021
Journal: Behav Brain Res
Title: Investigating the role of striatal dopamine receptor 2 in motor coordination and balance: Insights into the pathogenesis of DYT1 dystonia.
Volume: 403
Pages: 113137
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Publication
23018676 | J:190734
First Author: McCarthy DM
Year: 2012
Journal: Dev Neurosci
Title: Neurogenesis and neuronal migration in the forebrain of the TorsinA knockout mouse embryo.
Volume: 34
Issue: 4
Pages: 366-78
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Protein Coding Gene
MGP_CAROLIEiJ_G0023405 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1353568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025386 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025509 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024862 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024321 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
31891745 | J:291824
 
First Author: Yokoi F
Year: 2020
Journal: Behav Brain Res
Title: Improved survival and overt "dystonic" symptoms in a torsinA hypofunction mouse model.
Volume: 381
Pages: 112451
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Publication
15930383 | J:98716
First Author: Sharma N
Year: 2005
Journal: J Neurosci
Title: Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation.
Volume: 25
Issue: 22
Pages: 5351-5
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Publication
31618684 | J:311121
 
First Author: Yokoi F
Year: 2020
Journal: Neurobiol Dis
Title: Decreased number of striatal cholinergic interneurons and motor deficits in dopamine receptor 2-expressing-cell-specific Dyt1 conditional knockout mice.
Volume: 134
Pages: 104638
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Publication
34038798 | J:310427
 
First Author: Yokoi F
Year: 2021
Journal: Behav Brain Res
Title: Characterization of the direct pathway in Dyt1 ΔGAG heterozygous knock-in mice and dopamine receptor 1-expressing-cell-specific Dyt1 conditional knockout mice.
Volume: 411
Pages: 113381
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Publication
21479250 | J:171442
First Author: Zhang L
Year: 2011
Journal: PLoS One
Title: Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice.
Volume: 6
Issue: 3
Pages: e18357
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Publication
22391119 | J:185060
First Author: Yokoi F
Year: 2012
Journal: Behav Brain Res
Title: Improved motor performance in Dyt1 ΔGAG heterozygous knock-in mice by cerebellar Purkinje-cell specific Dyt1 conditional knocking-out.
Volume: 230
Issue: 2
Pages: 389-98
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Publication
26183317 | J:225496
 
First Author: Vanni V
Year: 2015
Journal: Exp Neurol
Title: Cerebellar synaptogenesis is compromised in mouse models of DYT1 dystonia.
Volume: 271
Pages: 457-67
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Publication
23185535 | J:195581
First Author: Li X
Year: 2012
Journal: PLoS One
Title: Evaluation of TorsinA as a target for Parkinson disease therapy in mouse models.
Volume: 7
Issue: 11
Pages: e50063
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Publication
25860259 | J:233515
First Author: Zhang L
Year: 2015
Journal: PLoS One
Title: Dopamine receptor and Gα(olf) expression in DYT1 dystonia mouse models during postnatal development.
Volume: 10
Issue: 4
Pages: e0123104
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Publication
25799505 | J:229189
First Author: Yokoi F
Year: 2015
Journal: PLoS One
Title: Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.
Volume: 10
Issue: 3
Pages: e0120916
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Publication
21995941 | J:180702
First Author: Dang MT
Year: 2012
Journal: Behav Brain Res
Title: An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice.
Volume: 226
Issue: 2
Pages: 465-72
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Publication
23967309 | J:204437
First Author: Yokoi F
Year: 2013
Journal: PLoS One
Title: Pre-synaptic release deficits in a DYT1 dystonia mouse model.
Volume: 8
Issue: 8
Pages: e72491
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Publication
25451552 | J:223864
 
First Author: Yokoi F
Year: 2015
Journal: Behav Brain Res
Title: Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ΔGAG heterozygous knock-in mice.
Volume: 279
Pages: 202-10
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Publication
20223934 | J:159239
First Author: Cao S
Year: 2010
Journal: Dis Model Mech
Title: Chemical enhancement of torsinA function in cell and animal models of torsion dystonia.
Volume: 3
Issue: 5-6
Pages: 386-96
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Publication
19619587 | J:154005
First Author: Yokoi F
Year: 2009
Journal: Neurosci Res
Title: Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in Dyt1 DeltaGAG knock-in mice.
Volume: 65
Issue: 3
Pages: 228-35
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Publication
27404940 | J:240836
 
First Author: DeSimone JC
Year: 2016
Journal: Neurobiol Dis
Title: In vivo imaging reveals impaired connectivity across cortical and subcortical networks in a mouse model of DYT1 dystonia.
Volume: 95
Pages: 35-45
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Publication
34398825 | J:343037
First Author: Cai H
Year: 2021
Journal: Aging (Albany NY)
Title: Inhibition of endoplasmic reticulum stress reverses synaptic plasticity deficits in striatum of DYT1 dystonia mice.
Volume: 13
Issue: 16
Pages: 20319-20334
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Publication
28673740 | J:259017
 
First Author: DeSimone JC
Year: 2017
Journal: Neurobiol Dis
Title: Forebrain knock-out of torsinA reduces striatal free-water and impairs whole-brain functional connectivity in a symptomatic mouse model of DYT1 dystonia.
Volume: 106
Pages: 124-132
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Publication
26052670 | J:223770
 
First Author: Pappas SS
Year: 2015
Journal: Elife
Title: Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons.
Volume: 4
Pages: e08352
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Publication
29186574 | J:257005
First Author: Pappas SS
Year: 2018
Journal: Hum Mol Genet
Title: TorsinA dysfunction causes persistent neuronal nuclear pore defects.
Volume: 27
Issue: 3
Pages: 407-420
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Publication
35304183 | J:322834
 
First Author: Kernodle K
Year: 2022
Journal: Behav Brain Res
Title: A dystonia mouse model with motor and sequencing deficits paralleling human disease.
Volume: 426
Pages: 113844
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Publication
28587876 | J:262125
 
First Author: Scarduzio M
Year: 2017
Journal: Exp Neurol
Title: Strength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia.
Volume: 295
Pages: 162-175
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Publication
23748075 | J:201535
 
First Author: Iwabuchi S
Year: 2013
Journal: Neurosci Lett
Title: Abnormal cytoplasmic calcium dynamics in central neurons of a dystonia mouse model.
Volume: 548
Pages: 61-6
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Publication
24503369 | J:258652
 
First Author: Martella G
Year: 2014
Journal: Neurobiol Dis
Title: Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.
Volume: 65
Pages: 124-32
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Publication
29504938 | J:263945
   
First Author: Maltese M
Year: 2018
Journal: Elife
Title: Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum.
Volume: 7
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Publication
32433955 | J:300226
First Author: Sciamanna G
Year: 2020
Journal: Cell Rep
Title: Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia.
Volume: 31
Issue: 7
Pages: 107644
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Publication
28198698 | J:242050
   
First Author: Fremont R
Year: 2017
Journal: Elife
Title: A role for cerebellum in the hereditary dystonia DYT1.
Volume: 6
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Publication
28242745 | J:247200
First Author: Saunders CA
Year: 2017
Journal: J Cell Biol
Title: TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement.
Volume: 216
Issue: 3
Pages: 657-674
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Publication
31669362 | J:285560
 
First Author: Gonzalez-Alegre P
Year: 2019
Journal: Neuroscience
Title: A Novel Transgenic Mouse Model to Investigate the Cell-Autonomous Effects of torsinA(ΔE) Expression in Striatal Output Neurons.
Volume: 422
Pages: 1-11
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691627
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Hindbrain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Eye
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718527
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Tongue
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Heart
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Lung
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702127
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Stomach
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Liver
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876727
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Spleen
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287427
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Intestine
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3653180
Assay Type: Western blot
Annotation Date: 2006-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3653354
Age: postnatal newborn
Specimen Label: Kidney
Detected: true
Specimen Num: 12
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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