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Search results 1 to 100 out of 423 for Tph1

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Type Details Score
Gene
7166 | TPH1
Type: gene
Organism: human
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Gene
466453 | TPH1
Type: gene
Organism: chimpanzee
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Gene
611956 | TPH1
Type: gene
Organism: dog, domestic
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Gene
781941 | TPH1
Type: gene
Organism: cattle
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Gene
395799 | TPH1
Type: gene
Organism: chicken
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Gene
695363 | TPH1
Type: gene
Organism: macaque, rhesus
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Gene
100497239 | tph1
Type: gene
Organism: frog, western clawed
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Gene
24848 | Tph1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:98796 | Tph1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:7548968
Assay Type: RT-PCR
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820117
Stage: TS17
Assay Id: MGI:7549136
Age: embryonic day 10.5
Image: 4
Specimen Label: tph1
Detected: true
Specimen Num: 1
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Publication
29123193 | J:253571
First Author: Weaver SR
Year: 2017
Journal: Sci Rep
Title: Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation.
Volume: 7
Issue: 1
Pages: 15155
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Publication
14597720 | J:99733
First Author: Côté F
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.
Volume: 100
Issue: 23
Pages: 13525-30
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GXD Expression
GXD Expression
     
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191498
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tph1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191498
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tph1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191498
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tph1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191498
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tph1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191498
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tph1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191498
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tph1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6185688
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191498
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tph1
Detected: true
Specimen Num: 5
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Publication
33427054 | J:304526
First Author: Cheng AA
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models.
Volume: 320
Issue: 3
Pages: E438-E452
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Publication
30518775 | J:268037
First Author: Kim H
Year: 2018
Journal: Sci Rep
Title: Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model.
Volume: 8
Issue: 1
Pages: 17642
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Publication
23516593 | J:199538
First Author: Suidan GL
Year: 2013
Journal: PLoS One
Title: Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities.
Volume: 8
Issue: 3
Pages: e59032
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Publication
19181488 | J:150616
First Author: Gutknecht L
Year: 2009
Journal: Eur Neuropsychopharmacol
Title: Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.
Volume: 19
Issue: 4
Pages: 266-82
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Publication
14960274 | J:90035
First Author: Matsuda M
Year: 2004
Journal: Dev Cell
Title: Serotonin regulates mammary gland development via an autocrine-paracrine loop.
Volume: 6
Issue: 2
Pages: 193-203
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Publication
25192038 | J:218305
First Author: Laporta J
Year: 2014
Journal: Mol Endocrinol
Title: Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling.
Volume: 28
Issue: 11
Pages: 1866-74
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Publication
25485911 | J:227945
First Author: Crane JD
Year: 2015
Journal: Nat Med
Title: Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis.
Volume: 21
Issue: 2
Pages: 166-72
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Publication
21788492 | J:175628
First Author: Amireault P
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice.
Volume: 108
Issue: 32
Pages: 13141-6
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Publication
36200294 | J:329896
First Author: Roberts DS
Year: 2022
Journal: Physiol Rep
Title: Serotonin-deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension.
Volume: 10
Issue: 19
Pages: e15482
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Publication
23754283 | J:202717
First Author: Ren G
Year: 2013
Journal: J Biol Chem
Title: Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase.
Volume: 288
Issue: 31
Pages: 22451-9
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Publication
24358245 | J:209858
First Author: Amireault P
Year: 2013
Journal: PLoS One
Title: Serotonin is a key factor for mouse red blood cell survival.
Volume: 8
Issue: 12
Pages: e83010
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Publication
22797248 | J:192793
First Author: Abid S
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice.
Volume: 303
Issue: 6
Pages: L500-8
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Publication
31974364 | J:288178
First Author: Yabut JM
Year: 2020
Journal: Nat Commun
Title: Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance.
Volume: 11
Issue: 1
Pages: 463
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Publication
30446669 | J:267516
First Author: Choi W
Year: 2018
Journal: Nat Commun
Title: Serotonin signals through a gut-liver axis to regulate hepatic steatosis.
Volume: 9
Issue: 1
Pages: 4824
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Publication
25864946 | J:222728
 
First Author: Oh CM
Year: 2015
Journal: Nat Commun
Title: Regulation of systemic energy homeostasis by serotonin in adipose tissues.
Volume: 6
Pages: 6794
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Publication
20938637 | J:165635
First Author: Schraenen A
Year: 2010
Journal: Diabetologia
Title: Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy.
Volume: 53
Issue: 12
Pages: 2589-99
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Publication
25299122 | J:223569
First Author: Laporta J
Year: 2014
Journal: PLoS One
Title: Peripheral serotonin regulates maternal calcium trafficking in mammary epithelial cells during lactation in mice.
Volume: 9
Issue: 10
Pages: e110190
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Publication
18923670 | J:144582
First Author: Savelieva KV
Year: 2008
Journal: PLoS One
Title: Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.
Volume: 3
Issue: 10
Pages: e3301
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Publication
17182745 | J:118743
First Author: Côté F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Maternal serotonin is crucial for murine embryonic development.
Volume: 104
Issue: 1
Pages: 329-34
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Publication
16581041 | J:109672
First Author: Sakowski SA
Year: 2006
Journal: Brain Res
Title: Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.
Volume: 1085
Issue: 1
Pages: 11-8
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Publication
34524861 | J:344059
First Author: Schneider MA
Year: 2021
Journal: Sci Transl Med
Title: Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models.
Volume: 13
Issue: 611
Pages: eabc8188
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Publication
34379673 | J:314341
First Author: Saponara E
Year: 2021
Journal: PLoS One
Title: Single or combined ablation of peripheral serotonin and p21 limit adipose tissue expansion and metabolic alterations in early adulthood in mice fed a normocaloric diet.
Volume: 16
Issue: 8
Pages: e0255687
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Publication
15858217 | J:100667
First Author: Amireault P
Year: 2005
Journal: Biol Reprod
Title: Serotonin and its antidepressant-sensitive transport in mouse cumulus-oocyte complexes and early embryos.
Volume: 73
Issue: 2
Pages: 358-65
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Publication
32160524 | J:288599
First Author: Flamar AL
Year: 2020
Journal: Immunity
Title: Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.
Volume: 52
Issue: 4
Pages: 606-619.e6
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Publication
23395646 | J:198847
First Author: Essien BE
Year: 2013
Journal: Gastroenterology
Title: ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.
Volume: 144
Issue: 7
Pages: 1466-77, 1477.e1-9
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Publication
21677183 | J:173536
First Author: Li Z
Year: 2011
Journal: J Neurosci
Title: Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.
Volume: 31
Issue: 24
Pages: 8998-9009
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Publication
17675372 | J:128704
First Author: Izikki M
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.
Volume: 293
Issue: 4
Pages: L1045-52
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Publication
18304982 | J:135685
First Author: Basu B
Year: 2008
Journal: Reproduction
Title: Serotonin in pre-implantation mouse embryos is localized to the mitochondria and can modulate mitochondrial potential.
Volume: 135
Issue: 5
Pages: 657-69
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Publication
25426873 | J:220766
First Author: Kim K
Year: 2015
Journal: Endocrinology
Title: Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state.
Volume: 156
Issue: 2
Pages: 444-52
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Publication
31806625 | J:284574
First Author: Moon JH
Year: 2020
Journal: Diabetes
Title: Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.
Volume: 69
Issue: 2
Pages: 205-214
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Publication
34871362 | J:346529
First Author: Chen Z
Year: 2022
Journal: Blood
Title: Intestinal IL-33 promotes platelet activity for neutrophil recruitment during acute inflammation.
Volume: 139
Issue: 12
Pages: 1878-1891
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Publication
27238716 | J:235000
 
First Author: Wu HH
Year: 2016
Journal: Placenta
Title: Differential patterning of genes involved in serotonin metabolism and transport in extra-embryonic tissues of the mouse.
Volume: 42
Pages: 74-83
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Publication
36323317 | J:333065
First Author: Xie Z
Year: 2022
Journal: Cell
Title: The gut-to-brain axis for toxin-induced defensive responses.
Volume: 185
Issue: 23
Pages: 4298-4316.e21
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Protein Coding Gene
MGP_CAROLIEiJ_G0029763 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032749 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031023 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012988 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030861 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
14697203 | J:87273
First Author: Walther DJ
Year: 2003
Journal: Cell
Title: Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.
Volume: 115
Issue: 7
Pages: 851-62
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Publication
29866843 | J:263953
First Author: De Vadder F
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks.
Volume: 115
Issue: 25
Pages: 6458-6463
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Publication
7968351 | J:19524
First Author: Huh SO
Year: 1994
Journal: Brain Res Mol Brain Res
Title: A 6.1 kb 5' upstream region of the mouse tryptophan hydroxylase gene directs expression of E. coli lacZ to major serotonergic brain regions and pineal gland in transgenic mice.
Volume: 24
Issue: 1-4
Pages: 145-52
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Publication
32978487 | J:296241
First Author: Nonogaki K
Year: 2020
Journal: Sci Rep
Title: Whey protein isolate inhibits hepatic FGF21 production, which precedes weight gain, hyperinsulinemia and hyperglycemia in mice fed a high-fat diet.
Volume: 10
Issue: 1
Pages: 15784
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Publication
24127620 | J:215839
First Author: Heredia DJ
Year: 2013
Journal: J Physiol
Title: Important role of mucosal serotonin in colonic propulsion and peristaltic reflexes: in vitro analyses in mice lacking tryptophan hydroxylase 1.
Volume: 591
Issue: 23
Pages: 5939-57
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Publication
30893598 | J:298864
First Author: Sibon D
Year: 2019
Journal: Cell Rep
Title: Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin.
Volume: 26
Issue: 12
Pages: 3246-3256.e4
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Publication
22308416 | J:182614
First Author: Chabbi-Achengli Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Decreased osteoclastogenesis in serotonin-deficient mice.
Volume: 109
Issue: 7
Pages: 2567-72
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Publication
21281798 | J:169081
First Author: Li N
Year: 2011
Journal: Am J Pathol
Title: Serotonin activates dendritic cell function in the context of gut inflammation.
Volume: 178
Issue: 2
Pages: 662-71
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Publication
16926160 | J:117283
First Author: Brunk I
Year: 2006
Journal: J Biol Chem
Title: The first luminal domain of vesicular monoamine transporters mediates G-protein-dependent regulation of transmitter uptake.
Volume: 281
Issue: 44
Pages: 33373-85
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Publication
18506000 | J:155085
First Author: Dempsie Y
Year: 2008
Journal: Circulation
Title: Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice.
Volume: 117
Issue: 22
Pages: 2928-37
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Publication
28855642 | J:255803
First Author: Bi J
Year: 2017
Journal: Sci Rep
Title: Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice.
Volume: 7
Issue: 1
Pages: 10001
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Publication
17130306 | J:135916
First Author: Morecroft I
Year: 2007
Journal: Hypertension
Title: Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension.
Volume: 49
Issue: 1
Pages: 232-6
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Publication
24520366 | J:212954
First Author: Herr N
Year: 2014
Journal: PLoS One
Title: Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice.
Volume: 9
Issue: 2
Pages: e88316
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Publication
26235267 | J:227731
First Author: Saponara E
Year: 2015
Journal: J Pathol
Title: Serotonin promotes acinar dedifferentiation following pancreatitis-induced regeneration in the adult pancreas.
Volume: 237
Issue: 4
Pages: 495-507
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Publication
19859528 | J:154588
First Author: Paulmann N
Year: 2009
Journal: PLoS Biol
Title: Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.
Volume: 7
Issue: 10
Pages: e1000229
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Publication
16601191 | J:144128
First Author: Lesurtel M
Year: 2006
Journal: Science
Title: Platelet-derived serotonin mediates liver regeneration.
Volume: 312
Issue: 5770
Pages: 104-7
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Publication
17681180 | J:128276
First Author: Nocito A
Year: 2007
Journal: Gastroenterology
Title: Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Volume: 133
Issue: 2
Pages: 608-18
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Publication
23243271 | J:194609
First Author: Duerschmied D
Year: 2013
Journal: Blood
Title: Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Volume: 121
Issue: 6
Pages: 1008-15
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Publication
18593914 | J:138879
First Author: Nocito A
Year: 2008
Journal: Cancer Res
Title: Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Volume: 68
Issue: 13
Pages: 5152-8
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Publication
21390323 | J:171043
First Author: Pai VP
Year: 2011
Journal: PLoS One
Title: Multiple cellular responses to serotonin contribute to epithelial homeostasis.
Volume: 6
Issue: 2
Pages: e17028
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Publication
6683693 | J:4454
First Author: Kulikov AV
Year: 1983
Journal: Genetika
Title: [Genetic control of tryptophan hydroxylase activity in the mouse brain].
Volume: 19
Issue: 5
Pages: 784-8
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Publication
1714508 | J:11377
First Author: Stoll J
Year: 1991
Journal: J Neurosci Res
Title: Isolation and structural characterization of the murine tryptophan hydroxylase gene.
Volume: 28
Issue: 4
Pages: 457-65
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Publication
10320783 | J:55029
First Author: Walther DJ
Year: 1999
Journal: Brain Res Mol Brain Res
Title: Serotonin synthesis in murine embryonic stem cells.
Volume: 68
Issue: 1-2
Pages: 55-63
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Publication
12406341 | J:80139
First Author: Slominski A
Year: 2002
Journal: J Invest Dermatol
Title: Serotoninergic system in hamster skin.
Volume: 119
Issue: 4
Pages: 934-42
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Publication
19064621 | J:176555
First Author: Neal KB
Year: 2009
Journal: J Physiol
Title: Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice.
Volume: 587
Issue: 3
Pages: 567-86
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Publication
31614319 | J:314422
 
First Author: Sugiyama E
Year: 2019
Journal: iScience
Title: Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging.
Volume: 20
Pages: 359-372
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GXD Expression
GXD Expression
     
Probe: MGI:3809727
Assay Type: RT-PCR
Annotation Date: 2008-10-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796528
Stage: TS28
Assay Id: MGI:3809733
Age: postnatal adult
Specimen Label: 1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3809727
Assay Type: RT-PCR
Annotation Date: 2008-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3809733
Age: embryonic day 1.0
Specimen Label: 2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3809727
Assay Type: RT-PCR
Annotation Date: 2008-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3809733
Age: embryonic day 2.5
Specimen Label: 3
Detected: false
Specimen Num: 3
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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