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Search results 1 to 100 out of 548 for Tph2

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0.048s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:7548969
Assay Type: RT-PCR
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820117
Stage: TS17
Assay Id: MGI:7549138
Age: embryonic day 10.5
Image: 4
Specimen Label: tph2
Detected: true
Specimen Num: 2
Publication  
First Author: Liu H
Year: 2021
Journal: Endocrinology
Title: TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner.
Volume: 162
Issue: 1
Publication
First Author: Gutknecht L
Year: 2008
Journal: J Neural Transm (Vienna)
Title: Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice.
Volume: 115
Issue: 8
Pages: 1127-32
Publication
First Author: Kulikov AV
Year: 2005
Journal: Genes Brain Behav
Title: Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains.
Volume: 4
Issue: 8
Pages: 482-5
Publication  
First Author: Mosienko V
Year: 2014
Journal: Neuropharmacology
Title: Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity.
Volume: 85
Pages: 73-80
Publication
First Author: Gutknecht L
Year: 2012
Journal: PLoS One
Title: Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.
Volume: 7
Issue: 8
Pages: e43157
Publication
First Author: Carli M
Year: 2015
Journal: J Neurochem
Title: Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.
Volume: 135
Issue: 4
Pages: 674-85
Publication
First Author: Pelosi B
Year: 2015
Journal: PLoS One
Title: Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.
Volume: 10
Issue: 8
Pages: e0136422
Publication
First Author: Gutknecht L
Year: 2009
Journal: Eur Neuropsychopharmacol
Title: Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.
Volume: 19
Issue: 4
Pages: 266-82
Publication
First Author: Gutknecht L
Year: 2015
Journal: Psychopharmacology (Berl)
Title: Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.
Volume: 232
Issue: 14
Pages: 2429-41
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191499
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tph2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191499
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tph2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191499
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tph2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191499
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tph2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191499
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tph2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191499
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tph2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185690
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191499
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tph2
Detected: true
Specimen Num: 7
Publication
First Author: Kriegebaum C
Year: 2010
Journal: Neurochem Int
Title: Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life.
Volume: 57
Issue: 5
Pages: 512-7
Publication  
First Author: Gorlova A
Year: 2020
Journal: J Affect Disord
Title: Stress-induced aggression in heterozygous TPH2 mutant mice is associated with alterations in serotonin turnover and expression of 5-HT6 and AMPA subunit 2A receptors.
Volume: 272
Pages: 440-451
Publication
First Author: Waider J
Year: 2013
Journal: Histochem Cell Biol
Title: GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice.
Volume: 139
Issue: 2
Pages: 267-81
GXD Expression
Probe: MGI:7575951
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576059
Age: embryonic day 14.5
Image: 7E' +/+
Note: A strong separation between the Th and Tph2 expression areas was seen.
Specimen Label: 7E' +/+
Detected: true
Specimen Num: 7
Publication      
First Author: Gloss B
Year: 2011
Journal: MGI Direct Data Submission
Title: Generation of an inducible Tph2 cre transgene
Publication
First Author: Zhang X
Year: 2004
Journal: Science
Title: Tryptophan hydroxylase-2 controls brain serotonin synthesis.
Volume: 305
Issue: 5681
Pages: 217
Publication
First Author: Tenner K
Year: 2008
Journal: Neurosci Lett
Title: The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains.
Volume: 431
Issue: 1
Pages: 21-5
Publication  
First Author: Mosienko V
Year: 2015
Journal: Behav Brain Res
Title: Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Volume: 277
Pages: 78-88
Publication  
First Author: Waider J
Year: 2019
Journal: Front Neurosci
Title: Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity.
Volume: 13
Pages: 245
Publication
First Author: Koshimizu H
Year: 2019
Journal: Neuropsychopharmacol Rep
Title: Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2.
Volume: 39
Issue: 1
Pages: 56-60
Publication  
First Author: Lieb MW
Year: 2019
Journal: Behav Brain Res
Title: Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice.
Volume: 373
Pages: 112086
Publication
First Author: Kästner N
Year: 2019
Journal: Sci Rep
Title: Brain serotonin deficiency affects female aggression.
Volume: 9
Issue: 1
Pages: 1366
Publication
First Author: Montalbano A
Year: 2015
Journal: Eur Neuropsychopharmacol
Title: Cellular resilience: 5-HT neurons in Tph2(-/-) mice retain normal firing behavior despite the lack of brain 5-HT.
Volume: 25
Issue: 11
Pages: 2022-35
Publication  
First Author: Bazovkina DV
Year: 2015
Journal: Neurosci Lett
Title: The C1473G polymorphism in the Tryptophan hydroxylase-2 gene: involvement in ethanol-related behavior in mice.
Volume: 589
Pages: 79-82
Publication
First Author: Siesser WB
Year: 2010
Journal: Neurosci Lett
Title: Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice.
Volume: 481
Issue: 1
Pages: 6-11
Publication
First Author: Aboagye B
Year: 2021
Journal: Sci Rep
Title: Serotonin deficiency induced after brain maturation rescues consequences of early life adversity.
Volume: 11
Issue: 1
Pages: 5368
Publication
First Author: Waider J
Year: 2017
Journal: Transl Psychiatry
Title: Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice.
Volume: 7
Issue: 10
Pages: e1246
Publication
First Author: Angoa-Pérez M
Year: 2012
Journal: J Neurochem
Title: Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity.
Volume: 121
Issue: 6
Pages: 974-84
Publication
First Author: Pho H
Year: 2022
Journal: Physiol Rep
Title: The effect of brain serotonin deficiency on breathing is magnified by age.
Volume: 10
Issue: 10
Pages: e15245
Publication
First Author: Maddaloni G
Year: 2018
Journal: Sci Rep
Title: Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress.
Volume: 8
Issue: 1
Pages: 11847
Publication  
First Author: Jørgensen CV
Year: 2013
Journal: Neurosci Lett
Title: Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice.
Volume: 555
Pages: 118-22
Publication
First Author: Omenetti A
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
Volume: 300
Issue: 2
Pages: G303-15
Publication  
First Author: Lemay F
Year: 2015
Journal: Neurosci Lett
Title: Increased ethanol consumption despite taste aversion in mice with a human tryptophan hydroxylase 2 loss of function mutation.
Volume: 609
Pages: 194-7
Publication
First Author: Sakowski SA
Year: 2006
Journal: J Neurochem
Title: Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function.
Volume: 96
Issue: 3
Pages: 758-65
Publication
First Author: Kulikov AV
Year: 2012
Journal: Behav Brain Res
Title: A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolism.
Volume: 233
Issue: 1
Pages: 113-9
Publication  
First Author: Bazhenova EY
Year: 2017
Journal: Neurosci Lett
Title: C1473G polymorphism in mouse tryptophan hydroxylase-2 gene in the regulation of the reaction to emotional stress.
Volume: 640
Pages: 105-110
Publication
First Author: Liu Y
Year: 2011
Journal: Nature
Title: Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice.
Volume: 472
Issue: 7341
Pages: 95-9
Publication  
First Author: Wong P
Year: 2015
Journal: Front Behav Neurosci
Title: Early life environmental and pharmacological stressors result in persistent dysregulations of the serotonergic system.
Volume: 9
Pages: 94
Publication  
First Author: Russo AM
Year: 2019
Journal: Behav Brain Res
Title: Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice.
Volume: 359
Pages: 918-926
Publication  
First Author: Campanelli F
Year: 2021
Journal: Neurobiol Dis
Title: Serotonin drives striatal synaptic plasticity in a sex-related manner.
Volume: 158
Pages: 105448
Publication  
First Author: Takahashi A
Year: 2014
Journal: Front Neurosci
Title: Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes.
Volume: 8
Pages: 156
Publication
First Author: Côté F
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.
Volume: 100
Issue: 23
Pages: 13525-30
Publication
First Author: Sakowski SA
Year: 2006
Journal: Brain Res
Title: Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.
Volume: 1085
Issue: 1
Pages: 11-8
Publication
First Author: Savelieva KV
Year: 2008
Journal: PLoS One
Title: Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.
Volume: 3
Issue: 10
Pages: e3301
Publication
First Author: Muzerelle A
Year: 2021
Journal: Sci Rep
Title: Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival.
Volume: 11
Issue: 1
Pages: 6004
Publication
First Author: Liu Y
Year: 2023
Journal: Neuron
Title: Molecular and cellular mechanisms of the first social relationship: A conserved role of 5-HT from mice to monkeys, upstream of oxytocin.
Volume: 111
Issue: 9
Pages: 1468-1485.e7
Publication
First Author: Beaulieu JM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.
Volume: 105
Issue: 4
Pages: 1333-8
Publication      
First Author: Zhu P
Year: 2022
Journal: Neuron
Title: 5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis.
Publication
First Author: Li Z
Year: 2011
Journal: J Neurosci
Title: Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.
Volume: 31
Issue: 24
Pages: 8998-9009
Publication
First Author: Izikki M
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.
Volume: 293
Issue: 4
Pages: L1045-52
Publication
First Author: Huo Y
Year: 2018
Journal: PLoS One
Title: Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala.
Volume: 13
Issue: 2
Pages: e0193395
Publication
First Author: Basu B
Year: 2008
Journal: Reproduction
Title: Serotonin in pre-implantation mouse embryos is localized to the mitochondria and can modulate mitochondrial potential.
Volume: 135
Issue: 5
Pages: 657-69
Publication  
First Author: Jia YF
Year: 2014
Journal: Front Behav Neurosci
Title: Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells.
Volume: 8
Pages: 325
Publication    
First Author: Donovan LJ
Year: 2019
Journal: Elife
Title: Lmx1b is required at multiple stages to build expansive serotonergic axon architectures.
Volume: 8
Publication
First Author: Kitt MM
Year: 2022
Journal: Cell Rep
Title: An adult-stage transcriptional program for survival of serotonergic connectivity.
Volume: 39
Issue: 3
Pages: 110711
Publication
First Author: Wu Q
Year: 2012
Journal: Nature
Title: Deciphering a neuronal circuit that mediates appetite.
Volume: 483
Issue: 7391
Pages: 594-7
Publication  
First Author: Teng T
Year: 2017
Journal: eNeuro
Title: EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.
Volume: 4
Issue: 1
Publication
First Author: Cai X
Year: 2022
Journal: Nat Neurosci
Title: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice.
Volume: 25
Issue: 5
Pages: 646-658
Publication  
First Author: Kouwenhoven WM
Year: 2021
Journal: Int J Mol Sci
Title: Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate.
Volume: 22
Issue: 23
Publication
First Author: Jacob J
Year: 2009
Journal: Development
Title: Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Volume: 136
Issue: 14
Pages: 2477-85
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Song NN
Year: 2016
Journal: Sci Rep
Title: Reducing central serotonin in adulthood promotes hippocampal neurogenesis.
Volume: 6
Pages: 20338
Publication  
First Author: Pratelli M
Year: 2017
Journal: eNeuro
Title: Perturbation of Serotonin Homeostasis during Adulthood Affects Serotonergic Neuronal Circuitry.
Volume: 4
Issue: 2
Publication  
First Author: Cai YQ
Year: 2014
Journal: Mol Pain
Title: Optogenetic activation of brainstem serotonergic neurons induces persistent pain sensitization.
Volume: 10
Pages: 70
Publication
First Author: Ren J
Year: 2018
Journal: Cell
Title: Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems.
Volume: 175
Issue: 2
Pages: 472-487.e20