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Search results 1 to 100 out of 205 for Trem1

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0.064s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: TREM1 (triggering receptor expressed on myeloid cells) is a receptor that activates neutrophils and monocytes/macrophages by signaling through the adapter protein DAP12 []. It trigger secretion of pro-inflammatory mediators and acts as an amplifier of inflammatory responses triggered by bacterial and fungal infections [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Liu Q
Year: 2019
Journal: Nat Immunol
Title: Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity.
Volume: 20
Issue: 8
Pages: 1023-1034
Publication  
First Author: Suh HC
Year: 2017
Journal: Sci Rep
Title: LPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytes.
Volume: 7
Pages: 46440
Publication  
First Author: Ajith A
Year: 2023
Journal: J Clin Invest
Title: Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance.
Volume: 133
Issue: 21
Publication
First Author: Chaney AM
Year: 2023
Journal: Sci Transl Med
Title: PET imaging of TREM1 identifies CNS-infiltrating myeloid cells in a mouse model of multiple sclerosis.
Volume: 15
Issue: 702
Pages: eabm6267
Publication
First Author: Du W
Year: 2017
Journal: Leukemia
Title: The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.
Volume: 31
Issue: 2
Pages: 423-433
Publication  
First Author: Li Z
Year: 2019
Journal: Biomed Pharmacother
Title: Inhibition of TREM1 reduces inflammation and oxidative stress after spinal cord injury (SCI) associated with HO-1 expressions.
Volume: 109
Pages: 2014-2021
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: false
Publication  
First Author: Colonna M
Year: 2003
Journal: J Infect Dis
Title: TREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses.
Volume: 187 Suppl 2
Pages: S397-401
Publication
First Author: Bouchon A
Year: 2001
Journal: Nature
Title: TREM-1 amplifies inflammation and is a crucial mediator of septic shock.
Volume: 410
Issue: 6832
Pages: 1103-7
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
Publication
First Author: Tammaro A
Year: 2013
Journal: PLoS One
Title: Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy.
Volume: 8
Issue: 12
Pages: e82498
Publication
First Author: Hommes TJ
Year: 2014
Journal: J Pathol
Title: Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia.
Volume: 233
Issue: 4
Pages: 357-67
Publication
First Author: Klesney-Tait J
Year: 2013
Journal: J Clin Invest
Title: Transepithelial migration of neutrophils into the lung requires TREM-1.
Volume: 123
Issue: 1
Pages: 138-49
Publication
First Author: McQueen BE
Year: 2021
Journal: Infect Immun
Title: Reduced Uterine Tissue Damage during Chlamydia muridarum Infection in TREM-1,3-Deficient Mice.
Volume: 89
Issue: 10
Pages: e0007221
Publication  
First Author: Kozik JH
Year: 2016
Journal: Sci Rep
Title: Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils.
Volume: 6
Pages: 28556
Publication
First Author: Wu J
Year: 2012
Journal: Cancer Res
Title: The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma.
Volume: 72
Issue: 16
Pages: 3977-86
Publication
First Author: Nguyen-Lefebvre AT
Year: 2018
Journal: J Clin Invest
Title: The innate immune receptor TREM-1 promotes liver injury and fibrosis.
Volume: 128
Issue: 11
Pages: 4870-4883
Publication  
First Author: Brustolin B
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Triggering receptor expressed on myeloid cells-1 deletion in mice attenuates high-fat diet-induced obesity.
Volume: 13
Pages: 983827
Publication
First Author: Saurer L
Year: 2017
Journal: Sci Rep
Title: TREM-1 promotes intestinal tumorigenesis.
Volume: 7
Issue: 1
Pages: 14870
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Weber B
Year: 2014
Journal: PLoS Pathog
Title: TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.
Volume: 10
Issue: 1
Pages: e1003900
Publication  
First Author: Siskind S
Year: 2022
Journal: Front Physiol
Title: Extracellular CIRP induces acute kidney injury via endothelial TREM-1.
Volume: 13
Pages: 954815
Publication  
First Author: Denning NL
Year: 2020
Journal: JCI Insight
Title: Extracellular CIRP as an endogenous TREM-1 ligand to fuel inflammation in sepsis.
Volume: 5
Issue: 5
Publication  
First Author: Fu L
Year: 2017
Journal: Front Immunol
Title: Identification of Extracellular Actin As a Ligand for Triggering Receptor Expressed on Myeloid Cells-1 Signaling.
Volume: 8
Pages: 917
Publication
First Author: Borjas T
Year: 2022
Journal: Shock
Title: Inhibition of the Interaction of TREM-1 and eCIRP Attenuates Inflammation and Improves Survival in Hepatic Ischemia/Reperfusion.
Volume: 57
Issue: 2
Pages: 246-255
Publication  
First Author: Tan C
Year: 2020
Journal: Front Cell Dev Biol
Title: Extracellular CIRP Induces Inflammation in Alveolar Type II Cells via TREM-1.
Volume: 8
Pages: 579157
Publication
First Author: Yang FC
Year: 2019
Journal: J Biomed Sci
Title: TREM-1-dependent M1 macrophage polarization restores intestinal epithelium damaged by DSS-induced colitis by activating IL-22-producing innate lymphoid cells.
Volume: 26
Issue: 1
Pages: 46
Publication
First Author: Feng JY
Year: 2021
Journal: Microbes Infect
Title: TREM-1 enhances Mycobacterium tuberculosis-induced inflammatory responses in macrophages.
Volume: 23
Issue: 1
Pages: 104765
Publication
First Author: Boufenzer A
Year: 2015
Journal: Circ Res
Title: TREM-1 Mediates Inflammatory Injury and Cardiac Remodeling Following Myocardial Infarction.
Volume: 116
Issue: 11
Pages: 1772-82
Publication
First Author: Gibot S
Year: 2004
Journal: J Exp Med
Title: A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
Volume: 200
Issue: 11
Pages: 1419-26
Publication
First Author: Gibot S
Year: 2007
Journal: Eur J Immunol
Title: TREM-1 promotes survival during septic shock in mice.
Volume: 37
Issue: 2
Pages: 456-66
Publication
First Author: Zeng H
Year: 2007
Journal: Eur J Immunol
Title: TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1.
Volume: 37
Issue: 8
Pages: 2300-8
Publication
First Author: Wu M
Year: 2011
Journal: Infect Immun
Title: TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses.
Volume: 79
Issue: 7
Pages: 2709-16
Publication
First Author: Wang F
Year: 2012
Journal: Cell Immunol
Title: Blocking TREM-1 signaling prolongs survival of mice with Pseudomonas aeruginosa induced sepsis.
Volume: 272
Issue: 2
Pages: 251-8
Publication
First Author: Lin YT
Year: 2014
Journal: Infect Immun
Title: TREM-1 promotes survival during Klebsiella pneumoniae liver abscess in mice.
Volume: 82
Issue: 3
Pages: 1335-42
Publication
First Author: Yang C
Year: 2015
Journal: Infect Immun
Title: TREM-1 signaling promotes host defense during the early stage of infection with highly pathogenic Streptococcus suis.
Volume: 83
Issue: 8
Pages: 3293-301
Publication
First Author: Yuan Z
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TREM-1-accentuated lung injury via miR-155 is inhibited by LP17 nanomedicine.
Volume: 310
Issue: 5
Pages: L426-38
Publication
First Author: Che X
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages.
Volume: 315
Issue: 1
Pages: G128-G139
Publication
First Author: Zhu H
Year: 2019
Journal: Microb Biotechnol
Title: TREM-1 deficiency attenuates the inflammatory responses in LPS-induced murine endometritis.
Volume: 12
Issue: 6
Pages: 1337-1345
Publication
First Author: Jolly L
Year: 2018
Journal: Cardiovasc Res
Title: Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock.
Volume: 114
Issue: 6
Pages: 907-918
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11545
Specimen Label: GUDMAP:11545
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001632
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542186
Age: embryonic day 15.5
Image: GUDMAP:11560
Specimen Label: GUDMAP:11560
Detected: false
Specimen Num: 2
Publication    
First Author: Bouchin A
Year: 2000
Journal: GenBank Submission
Title: Mus musculus TREM-1 mRNA, complete cds
Pages: AF241219
Publication
First Author: Lo TH
Year: 2014
Journal: Kidney Int
Title: TREM-1 regulates macrophage polarization in ureteral obstruction.
Volume: 86
Issue: 6
Pages: 1174-86
Publication  
First Author: Yamaga S
Year: 2023
Journal: Front Immunol
Title: Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice.
Volume: 14
Pages: 1151250
Publication
First Author: Lagler H
Year: 2009
Journal: J Immunol
Title: TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Volume: 183
Issue: 3
Pages: 2027-36
Publication
First Author: Bouchon A
Year: 2000
Journal: J Immunol
Title: Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.
Volume: 164
Issue: 10
Pages: 4991-5
Publication  
First Author: Wu K
Year: 2023
Journal: Brain Behav Immun
Title: The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
Volume: 112
Pages: 96-117
Publication  
First Author: Zysset D
Year: 2016
Journal: Nat Commun
Title: TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis.
Volume: 7
Pages: 13151
Publication  
First Author: Liu CJ
Year: 2017
Journal: J Autoimmun
Title: Triggering receptor expressed on myeloid cells-1 (TREM-1) deficiency augments BAFF production to promote lupus progression.
Volume: 78
Pages: 92-100
Publication
First Author: Su VY
Year: 2019
Journal: Stem Cells
Title: Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.
Volume: 37
Issue: 5
Pages: 631-639
Publication
First Author: Chung DH
Year: 2002
Journal: Eur J Immunol
Title: Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.
Volume: 32
Issue: 1
Pages: 59-66