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Search results 1 to 100 out of 547 for Trim5

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
85363 | TRIM5
Type: gene
Organism: human
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Gene
503563 | TRIM5
Type: gene
Organism: chimpanzee
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Gene
505265 | TRIM5
Type: gene
Organism: cattle
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Gene
574288 | TRIM5
Type: gene
Organism: macaque, rhesus
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Gene
308906 | Trim5
Type: gene
Organism: rat
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Protein Coding Gene
MGI:3646853 | Trim5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032917 | TRIM5
Type: Family
Description: Tripartite motif-containing protein 5 (TRIM5) is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus invasion of the target cell cytoplasm []. It is a regulator of autophagy [].Interestingly, while each primate species has a single TRIM5 gene, mice have at least seven TRIM5 homologues that cluster into two groups, Trim12a, -b, and -c and Trim30a, -b, -c, and -d. The three Trim12 proteins activated innate immune signaling, while the Trim30 proteins did not [].
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Publication
19147168 | J:162981
First Author: Tareen SU
Year: 2009
Journal: Virology
Title: An expanded clade of rodent Trim5 genes.
Volume: 385
Issue: 2
Pages: 473-83
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Publication
19238338 | J:146217
First Author: Johnson WE
Year: 2009
Journal: Immunogenetics
Title: Molecular evolution of the antiretroviral TRIM5 gene.
Volume: 61
Issue: 3
Pages: 163-76
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Publication
21512573 | -
First Author: Pertel T
Year: 2011
Journal: Nature
Title: TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
Volume: 472
Issue: 7343
Pages: 361-5
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Publication
26468522 | -
First Author: Lascano J
Year: 2015
Journal: J Virol
Title: TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.
Volume: 90
Issue: 1
Pages: 308-16
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Publication
25127057 | -
First Author: Mandell MA
Year: 2014
Journal: Dev Cell
Title: TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
Volume: 30
Issue: 4
Pages: 394-409
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Protein
Q3UUU9
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: true
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Protein
Q99PQ1
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
D3YVI1
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Protein
Q6P6F6
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
A0A0R4J1B5
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
Q504P5
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
D3YYU4
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Protein
Q8CC73
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0030188 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3646853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032516 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033221 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013404 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031296 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6507606
Assay Type: RT-PCR
Annotation Date: 2021-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507621
Age: postnatal
Image: 13
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6507606
Assay Type: RT-PCR
Annotation Date: 2021-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507621
Age: postnatal
Image: 13
Specimen Label: gHO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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Publication
19706712 | J:248997
First Author: Boon AC
Year: 2009
Journal: J Virol
Title: Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.
Volume: 83
Issue: 20
Pages: 10417-26
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Publication
32099945 | J:282838
First Author: Fan J
Year: 2020
Journal: J Endocr Soc
Title: Amhr2-Cre-Mediated Global Tspo Knockout.
Volume: 4
Issue: 2
Pages: bvaa001
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
26503954 | J:287707
First Author: Chang TH
Year: 2015
Journal: J Immunol
Title: Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6.
Volume: 195
Issue: 11
Pages: 5367-79
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Publication
16445939 | -
First Author: Mateja A
Year: 2006
Journal: J Mol Biol
Title: The dimerization mechanism of LIS1 and its implication for proteins containing the LisH motif.
Volume: 357
Issue: 2
Pages: 621-31
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Protein Domain
IPR027370 | Znf-RING_euk
Type: Domain
Description: This zinc-finger is typical of ubiquitin ligases from eukaryotes [, ]. This domain can also be found in Tripartite motif-containing proteins (TRIM), including TRIM5 from humans, a capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses [, ].
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Publication
22078707 | J:196249
 
First Author: Lukic Z
Year: 2011
Journal: Retrovirology
Title: TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions.
Volume: 8
Pages: 93
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Protein Coding Gene
MGI:4821183 | Trim12c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0030187 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGI:4821256 | Trim30b
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0030189 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGI:4821257 | Trim30c
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0030190 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGI:1923931 | Trim12a
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0032709 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0032712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0032714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0032715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:3035181 | Trim30d
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0032717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0032684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0032687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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