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Search results 1 to 100 out of 845 for Trio

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
7204 | TRIO
Type: gene
Organism: human
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Gene
100170157 | trio
Type: gene
Organism: frog, western clawed
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Gene
310192 | Trio
Type: gene
Organism: rat
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Gene
461730 | TRIO
Type: gene
Organism: chimpanzee
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Gene
478610 | TRIO
Type: gene
Organism: dog, domestic
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Gene
538292 | TRIO
Type: gene
Organism: cattle
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Gene
420919 | TRIO
Type: gene
Organism: chicken
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Gene
717492 | TRIO
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1927230 | Trio
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
105375116 | LOC105375116
Type: gene
Organism: human
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Gene
144667551 | TRIO-AS1
Type: gene
Organism: human
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Publication
30840899 | J:280186
First Author: Katrancha SM
Year: 2019
Journal: Cell Rep
Title: Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits.
Volume: 26
Issue: 10
Pages: 2805-2817.e9
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Publication
11148140 | J:113879
First Author: Seipel K
Year: 2001
Journal: J Cell Sci
Title: Tara, a novel F-actin binding protein, associates with the Trio guanine nucleotide exchange factor and regulates actin cytoskeletal organization.
Volume: 114
Issue: Pt 2
Pages: 389-99
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Publication
25727174 | J:221044
 
First Author: Zong W
Year: 2015
Journal: Brain Res
Title: Trio gene is required for mouse learning ability.
Volume: 1608
Pages: 82-90
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Publication
31152060 | J:280738
First Author: Tao T
Year: 2019
Journal: J Biol Chem
Title: Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth.
Volume: 294
Issue: 28
Pages: 10954-10968
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Publication
32898553 | J:301093
First Author: Gu J
Year: 2020
Journal: Exp Cell Res
Title: Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42.
Volume: 396
Issue: 1
Pages: 112265
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Publication
18212043 | J:134213
First Author: Brian?on-Marjollet A
Year: 2008
Journal: Mol Cell Biol
Title: Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.
Volume: 28
Issue: 7
Pages: 2314-23
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Publication
33754063 | J:308974
First Author: Guo S
Year: 2021
Journal: Theranostics
Title: Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
Volume: 11
Issue: 9
Pages: 4316-4334
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Publication
17332503 | J:127493
First Author: Charrasse S
Year: 2007
Journal: Mol Biol Cell
Title: M-cadherin activates Rac1 GTPase through the Rho-GEF trio during myoblast fusion.
Volume: 18
Issue: 5
Pages: 1734-43
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Publication
17898204 | J:125289
First Author: Backer S
Year: 2007
Journal: J Neurosci
Title: Trio controls the mature organization of neuronal clusters in the hindbrain.
Volume: 27
Issue: 39
Pages: 10323-32
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Publication
30463880 | J:272912
First Author: Kruse K
Year: 2019
Journal: J Cell Biol
Title: N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.
Volume: 218
Issue: 1
Pages: 299-316
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Publication
26858404 | J:230424
First Author: Herring BE
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.
Volume: 113
Issue: 8
Pages: 2264-9
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Publication
30177526 | J:266538
 
First Author: Backer S
Year: 2018
Journal: Development
Title: Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring.
Volume: 145
Issue: 19
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Publication
28973398 | J:253460
First Author: Katrancha SM
Year: 2017
Journal: Hum Mol Genet
Title: Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity.
Volume: 26
Issue: 23
Pages: 4728-4740
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Gene
11078 | TRIOBP
Type: gene
Organism: human
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Publication
11050238 | J:65380
First Author: O'Brien SP
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.
Volume: 97
Issue: 22
Pages: 12074-8
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Publication
30850274 | J:291412
First Author: Tao T
Year: 2019
Journal: J Genet Genomics
Title: Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons.
Volume: 46
Issue: 2
Pages: 87-96
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Publication
33963279 | J:321518
First Author: Sun X
Year: 2021
Journal: Mol Psychiatry
Title: Dysfunction of Trio GEF1 involves in excitatory/inhibitory imbalance and autism-like behaviors through regulation of interneuron migration.
Volume: 26
Issue: 12
Pages: 7621-7640
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Publication
40488445 | J:387264
   
First Author: Ishchenko Y
Year: 2025
Journal: Elife
Title: Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice.
Volume: 13
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Publication
30268758 | J:269614
First Author: Chen H
Year: 2018
Journal: Exp Cell Res
Title: The role of Rho-GEF Trio in regulating tooth root development through the p38 MAPK pathway.
Volume: 372
Issue: 2
Pages: 158-167
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Publication
20516067 | J:165902
First Author: Peng YJ
Year: 2010
Journal: J Biol Chem
Title: Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum.
Volume: 285
Issue: 32
Pages: 24834-44
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Publication
39300136 | J:359240
First Author: Eid L
Year: 2025
Journal: Mol Psychiatry
Title: Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons.
Volume: 30
Issue: 4
Pages: 1338-1358
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Publication
21482718 | J:171349
First Author: Yano T
Year: 2011
Journal: J Cell Biol
Title: Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling.
Volume: 193
Issue: 2
Pages: 319-32
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Publication
31217345 | J:290568
 
First Author: Katsuno T
Year: 2019
Journal: JCI Insight
Title: TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.
Volume: 4
Issue: 12
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Publication
22031541 | J:178697
First Author: Plageman TF Jr
Year: 2011
Journal: Development
Title: A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination.
Volume: 138
Issue: 23
Pages: 5177-88
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Publication
16914736 | J:112170
First Author: Dalkilic I
Year: 2006
Journal: Mol Cell Biol
Title: Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure.
Volume: 26
Issue: 17
Pages: 6522-34
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Publication
25065758 | J:385204
First Author: van Haren J
Year: 2014
Journal: Curr Biol
Title: Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.
Volume: 24
Issue: 15
Pages: 1778-85
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Publication
16943433 | J:112304
First Author: Sun YJ
Year: 2006
Journal: Mol Cell Biol
Title: Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation.
Volume: 26
Issue: 18
Pages: 6923-35
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Publication
25432929 | J:221979
First Author: Sonoshita M
Year: 2015
Journal: Cancer Discov
Title: Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO.
Volume: 5
Issue: 2
Pages: 198-211
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Protein Coding Gene
MGP_CAROLIEiJ_G0019704 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200026597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00200054388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195013516 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00195055289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220024209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00220054536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180005345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00180055416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175004647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00175054763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1927230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215004801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00215055550 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210024007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00210054824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185022693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00185057761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205012204 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00205054431 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230014522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00230055688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190012133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00190054860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225031755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSGG00225055547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016080 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010023033 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29160307 | J:254153
First Author: Polacheck WJ
Year: 2017
Journal: Nature
Title: A non-canonical Notch complex regulates adherens junctions and vascular barrier function.
Volume: 552
Issue: 7684
Pages: 258-262
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Publication
- | J:217444
     
First Author: Debant A
Year: 2015
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Trios floxed allele
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Publication
23177739 | J:194217
First Author: Vaqu? JP
Year: 2013
Journal: Mol Cell
Title: A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.
Volume: 49
Issue: 1
Pages: 94-108
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GXD Expression
GXD Expression
     
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3693314
Age: postnatal
Specimen Label: cb +
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:3693314
Age: postnatal
Specimen Label: cr +
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3693314
Age: postnatal
Specimen Label: cb +
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
       
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:3693314
Age: postnatal
Specimen Label: cb +
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3693345
Assay Type: Western blot
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3693348
Age: postnatal
Specimen Label: cerebellum
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:3693355
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3693303
Assay Type: RT-PCR
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3693355
Age: postnatal day 56
Specimen Label: P56
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6285995
Assay Type: Western blot
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266522
Stage: TS22
Assay Id: MGI:6286048
Age: embryonic day 14.0
Image: 1
Specimen Label: GE
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6285995
Assay Type: Western blot
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:6286048
Age: embryonic day 14.0
Image: 1
Specimen Label: Th
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6285995
Assay Type: Western blot
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:6286048
Age: embryonic day 14.0
Image: 1
Specimen Label: VT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:8172587
Assay Type: RT-PCR
Annotation Date: 2025-04-18
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:8172614
Age: embryonic day 15.5
Image: 8
Specimen Label: 15.5 dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:8172587
Assay Type: RT-PCR
Annotation Date: 2025-04-18
Strength: Present
Sex: Female
Emaps: EMAPS:1796225
Stage: TS25
Assay Id: MGI:8172614
Age: embryonic day 17.5
Image: 8
Specimen Label: 17.5 dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:8343206
Assay Type: Western blot
Annotation Date: 2026-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:8343208
Age: embryonic day 17.0
Specimen Label: Lysate
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:8343206
Assay Type: Western blot
Annotation Date: 2026-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:8343210
Age: embryonic day 17.0
Specimen Label: Lysate
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6285995
Assay Type: Immunohistochemistry
Annotation Date: 2025-12-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Widespread
Stage: TS17
Assay Id: MGI:8270672
Age: embryonic day 10.5
Image: 3F pa1
Specimen Label: 3F pa1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3693301
Assay Type: RNA in situ
Annotation Date: 2007-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3693315
Age: postnatal day 24
Note: Expression is more intense in this brain region than in some other regions.
Specimen Label: 2Ba
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Pattern: Widespread
Stage: TS20
Assay Id: MGI:6286062
Age: embryonic day 12.5
Image: 2A
Note: Very broad expression.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Pattern: Widespread
Stage: TS20
Assay Id: MGI:6286062
Age: embryonic day 12.5
Image: 2B
Note: Very broad expression.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6286062
Age: embryonic day 14.5
Image: 2D
Specimen Label: 2D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6286062
Age: postnatal day 0
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6286062
Age: postnatal day 0
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3538022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6286062
Age: embryonic day 14.5
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4425507
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828922
Age: embryonic day 14.5
Image: euxassay_013122_07
Specimen Label: euxassay_013122_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4425507
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828922
Age: embryonic day 14.5
Image: euxassay_013122_17
Specimen Label: euxassay_013122_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6286062
Age: embryonic day 12.5
Specimen Label: not shown
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6286062
Age: embryonic day 14.5
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6286062
Age: postnatal day 0
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6286024
Assay Type: RNA in situ
Annotation Date: 2019-04-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6286062
Age: embryonic day 14.5
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4425507
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540434
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425507
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540434
Age: embryonic day 14.5
Note: Intermediate zone expression was greater than in the ventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•




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