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Search results 1 to 100 out of 7809 for Trp53

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Hits by Pathway

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Type Details Score
Gene
key_26784 | TRP53
Type: gene
Organism: cat, domestic
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Protein Coding Gene
MGI:98834 | Trp53
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7548335
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548368
Age: embryonic day 14.5
Image: 3A CC3 Trp53 cKO
Note: Authors report a lack of significant cell death in wild type and Trp53 cKO groups.
Specimen Label: 3A CC3 Trp53 cKO
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3J gH2AX Trp53 cKO
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3J gH2AX Trp53 cKO
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7548335
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548368
Age: embryonic day 14.5
Image: 3J CC3 Trp53 cKO
Note: Authors report a lack of significant cell death in wild type and Trp53 cKO groups.
Specimen Label: 3J CC3 Trp53 cKO
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3G gH2AX Trp53 cKO
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3G gH2AX Trp53 cKO
Specimen Num: 2
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Publication
15181534 | J:97137
First Author: Evans SC
Year: 2004
Journal: Mamm Genome
Title: A novel genetic modifier of p53, mop1, results in embryonic lethality.
Volume: 15
Issue: 6
Pages: 415-23
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QTL
MGI:3575566 | Motp1
Type: QTL
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7548333
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548366
Age: embryonic day 14.5
Image: 2A P21 Trp53 cKO
Specimen Label: 2A P21 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7548334
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548367
Age: embryonic day 14.5
Image: 2C F4/80 Trp53 cKO
Specimen Label: 2C F4/80 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7520107
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548370
Age: embryonic day 14.5
Image: 3A MMP2 Trp53 cKO
Specimen Label: 3A MMP2 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548373
Age: embryonic day 14.5
Image: 4D PAX6 Trp53 cKO
Specimen Label: 4D PAX6 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548373
Age: embryonic day 14.5
Image: 4H PAX6 Trp53 cKO
Specimen Label: 4H PAX6 Trp53 cKO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5295881
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548374
Age: embryonic day 14.5
Image: 4F SOX9 Trp53 cKO
Specimen Label: 4F SOX9 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5587805
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548376
Age: embryonic day 14.5
Image: 5A TBR2 Trp53 cKO
Specimen Label: 5A TBR2 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548377
Age: embryonic day 14.5
Image: 5C CTIP2 Trp53 cKO
Note: Expression not altered compared to wild type.
Specimen Label: 5C CTIP2 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7548377
Age: postnatal day 21
Image: 7E CTIP2 Trp53 cKO
Note: Expression not altered compared to wild type.
Specimen Label: 7E CTIP2 Trp53 cKO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5750655
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7548381
Age: postnatal day 21
Image: 7D FOXP2 Trp53 cKO
Note: Expression not altered compared to wild type.
Specimen Label: 7D FOXP2 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7548337
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7548383
Age: postnatal day 21
Image: 7F CUX1 Trp53 cKO
Note: Expression not altered compared to wild type.
Specimen Label: 7F CUX1 Trp53 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7548377
Age: postnatal day 21
Image: 8C CTIP2 Trp53 cKO
Note: Expression not altered compared to wild type.
Specimen Label: 8C CTIP2 Trp53 cKO
Detected: true
Specimen Num: 10
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Publication
23772033 | J:204954
First Author: Spehlmann ME
Year: 2013
Journal: J Immunol
Title: Trp53 deficiency protects against acute intestinal inflammation.
Volume: 191
Issue: 2
Pages: 837-47
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Publication
21402876 | J:182972
First Author: Sun Y
Year: 2011
Journal: J Cell Sci
Title: Trp53 regulates Notch 4 signaling through Mdm2.
Volume: 124
Issue: Pt 7
Pages: 1067-76
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Publication
21471252 | J:174321
First Author: Zhang S
Year: 2011
Journal: FASEB J
Title: Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis.
Volume: 25
Issue: 7
Pages: 2387-98
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Publication
27542204 | J:310028
First Author: Yue Y
Year: 2016
Journal: Oncotarget
Title: Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice.
Volume: 7
Issue: 38
Pages: 61874-61889
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Publication
30262850 | J:268678
First Author: Zhang Y
Year: 2018
Journal: Nat Commun
Title: Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.
Volume: 9
Issue: 1
Pages: 3953
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GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311705
Age: embryonic day 10.5
Image: S5B H2ax Trp53 Het (left)
Specimen Label: S5B H2ax Trp53 Het (left)
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311705
Age: embryonic day 10.5
Image: S5B H2ax Trp53 Het (right)
Specimen Label: S5B H2ax Trp53 Het (right)
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311705
Age: embryonic day 10.5
Image: S5B H2ax Trp53 KO (left)
Specimen Label: S5B H2ax Trp53 KO (left)
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311705
Age: embryonic day 10.5
Image: S5B H2ax Trp53 KO (right)
Specimen Label: S5B H2ax Trp53 KO (right)
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311707
Age: embryonic day 10.5
Image: S5B Casp3 Trp53 Het (left)
Specimen Label: S5B Casp3 Trp53 Het (left)
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311707
Age: embryonic day 10.5
Image: S5B Casp3 Trp53 Het (right)
Specimen Label: S5B Casp3 Trp53 Het (right)
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311707
Age: embryonic day 10.5
Image: S5B Casp3 Trp53 KO (left)
Specimen Label: S5B Casp3 Trp53 KO (left)
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7311707
Age: embryonic day 10.5
Image: S5B Casp3 Trp53 KO (right)
Specimen Label: S5B Casp3 Trp53 KO (right)
Detected: true
Specimen Num: 16
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Publication
10749125 | J:61422
First Author: Reis AM
Year: 2000
Journal: Cancer Res
Title: Genotype-specific Trp53 mutational analysis in ultraviolet B radiation-induced skin cancers in Xpc and Xpc Trp53 mutant mice.
Volume: 60
Issue: 6
Pages: 1571-9
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Publication
21445009 | J:211918
First Author: Wei QX
Year: 2011
Journal: Cell Cycle
Title: Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specific Trp53 platform.
Volume: 10
Issue: 8
Pages: 1261-70
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Publication
18310506 | J:133144
First Author: Morton JP
Year: 2008
Journal: Am J Pathol
Title: Trp53 deletion stimulates the formation of metastatic pancreatic tumors.
Volume: 172
Issue: 4
Pages: 1081-7
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Publication
22674894 | J:264273
First Author: Haley VL
Year: 2012
Journal: EMBO Mol Med
Title: Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.
Volume: 4
Issue: 8
Pages: 705-18
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Publication
32568216 | J:309362
First Author: Cochrane CR
Year: 2020
Journal: J Clin Invest
Title: Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling.
Volume: 130
Issue: 8
Pages: 4006-4018
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Publication
22370638 | J:193376
First Author: van der Weyden L
Year: 2013
Journal: Oncogene
Title: Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity.
Volume: 32
Issue: 3
Pages: 397-402
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Publication
18245467 | J:131867
First Author: Martínez-Cruz AB
Year: 2008
Journal: Cancer Res
Title: Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors.
Volume: 68
Issue: 3
Pages: 683-92
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Publication
28553932 | J:251276
First Author: Harlander S
Year: 2017
Journal: Nat Med
Title: Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice.
Volume: 23
Issue: 7
Pages: 869-877
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Publication
28076846 | J:272535
First Author: Baburamani AA
Year: 2017
Journal: Oncotarget
Title: Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia.
Volume: 8
Issue: 7
Pages: 12081-12092
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Publication
28059767 | J:237907
First Author: Ku SY
Year: 2017
Journal: Science
Title: Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
Volume: 355
Issue: 6320
Pages: 78-83
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Publication
14522252 | J:86077
First Author: Meuwissen R
Year: 2003
Journal: Cancer Cell
Title: Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model.
Volume: 4
Issue: 3
Pages: 181-9
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Publication
14706339 | J:89283
First Author: Fleischmann A
Year: 2003
Journal: Cancer Cell
Title: Rhabdomyosarcoma development in mice lacking Trp53 and Fos: tumor suppression by the Fos protooncogene.
Volume: 4
Issue: 6
Pages: 477-82
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Publication
24832557 | J:211653
First Author: Rahrmann EP
Year: 2014
Journal: Am J Pathol
Title: Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
Volume: 184
Issue: 7
Pages: 2082-98
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Publication
15222780 | J:91630
First Author: Mitchel RE
Year: 2004
Journal: Radiat Res
Title: Upper dose thresholds for radiation-induced adaptive response against cancer in high-dose-exposed, cancer-prone, radiation-sensitive Trp53 heterozygous mice.
Volume: 162
Issue: 1
Pages: 20-30
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Publication
22759378 | J:189180
First Author: Burnum KE
Year: 2012
Journal: Endocrinology
Title: Uterine deletion of Trp53 compromises antioxidant responses in the mouse decidua.
Volume: 153
Issue: 9
Pages: 4568-79
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Publication
22930559 | J:320931
First Author: Korpershoek E
Year: 2012
Journal: Endocr Relat Cancer
Title: Trp53 inactivation leads to earlier phaeochromocytoma formation in pten knockout mice.
Volume: 19
Issue: 6
Pages: 731-40
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Publication
33070870 | J:312820
First Author: Meyer AE
Year: 2020
Journal: Neoplasia
Title: Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation.
Volume: 22
Issue: 11
Pages: 644-658
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Publication
20585617 | J:161511
First Author: Francis JC
Year: 2010
Journal: PLoS Genet
Title: Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.
Volume: 6
Issue: 6
Pages: e1000995
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Publication
22139338 | J:333316
First Author: Golas A
Year: 2011
Journal: Reprod Biol
Title: Semen quality parameters and embryo lethality in mice deficient for Trp53 protein.
Volume: 11
Issue: 3
Pages: 250-63
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Publication
19281769 | J:147066
First Author: Couto SS
Year: 2009
Journal: Differentiation
Title: Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.
Volume: 77
Issue: 1
Pages: 103-11
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Publication
38110554 | J:345063
First Author: Brennan MS
Year: 2024
Journal: Cell Death Differ
Title: Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice.
Volume: 31
Issue: 2
Pages: 159-169
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Publication
22441798 | J:185824
First Author: Li A
Year: 2012
Journal: Biol Reprod
Title: The effect of Trp53 gene-dosage and parent-of-origin of inheritance on mouse gamete and embryo function in vitro.
Volume: 86
Issue: 6
Pages: 175
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Publication
15010313 | J:88558
First Author: Nahari D
Year: 2004
Journal: DNA Repair (Amst)
Title: Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair process.
Volume: 3
Issue: 4
Pages: 379-86
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Publication
11528400 | J:71532
First Author: Parant J
Year: 2001
Journal: Nat Genet
Title: Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
Volume: 29
Issue: 1
Pages: 92-5
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Publication
25622902 | J:244442
First Author: Cai KQ
Year: 2015
Journal: Neoplasia
Title: Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice.
Volume: 17
Issue: 1
Pages: 89-100
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Publication
12600234 | J:81935
First Author: Mitchel RE
Year: 2003
Journal: Radiat Res
Title: Low doses of radiation increase the latency of spontaneous lymphomas and spinal osteosarcomas in cancer-prone, radiation-sensitive Trp53 heterozygous mice.
Volume: 159
Issue: 3
Pages: 320-7
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Publication
11890468 | J:75222
First Author: Floyd E
Year: 2002
Journal: Toxicol Pathol
Title: The Trp53 hemizygous mouse in pharmaceutical development: points to consider for pathologists.
Volume: 30
Issue: 1
Pages: 147-56
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Publication
10973245 | J:64367
First Author: Jimenez GS
Year: 2000
Journal: Nat Genet
Title: A transactivation-deficient mouse model provides insights into Trp53 regulation and function.
Volume: 26
Issue: 1
Pages: 37-43
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Publication
31959748 | J:286306
First Author: Rose Li Y
Year: 2020
Journal: Nat Commun
Title: Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice.
Volume: 11
Issue: 1
Pages: 394
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Publication
11695559 | J:73020
 
First Author: French J
Year: 2001
Journal: Toxicol Pathol
Title: The nature of the heterozygous Trp53 knockout model for identification of mutagenic carcinogens.
Volume: 29 Suppl
Pages: 24-9
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GXD Expression
GXD Expression
Probe: MGI:6383198
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-29
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7341542
Age: embryonic day 10.5
Image: 2C Eftud2ncc-/-;Trp53ncc-/-
Note: Expression not affected by Trp53 genotype.
Specimen Label: 2C Eftud2ncc-/-;Trp53ncc-/-
Detected: true
Specimen Num: 8
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Publication
21665149 | J:173560
First Author: Sutherland KD
Year: 2011
Journal: Cancer Cell
Title: Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.
Volume: 19
Issue: 6
Pages: 754-64
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Publication
25468973 | J:217809
First Author: Rashkovan M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination.
Volume: 111
Issue: 50
Pages: E5411-9
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Publication
23319800 | J:196904
First Author: Guo G
Year: 2013
Journal: Cancer Res
Title: Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.
Volume: 73
Issue: 6
Pages: 1668-75
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Publication
15489287 | J:93444
First Author: Keller C
Year: 2004
Journal: Genes Dev
Title: Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.
Volume: 18
Issue: 21
Pages: 2614-26
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Publication
20234817 | J:162038
First Author: Tonks ID
Year: 2010
Journal: Neoplasia
Title: Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.
Volume: 12
Issue: 3
Pages: 235-43
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Publication
24232507 | J:318855
First Author: Brosius SN
Year: 2014
Journal: Acta Neuropathol
Title: Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.
Volume: 127
Issue: 4
Pages: 573-91
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Publication
34557915 | J:311932
 
First Author: White AK
Year: 2021
Journal: Development
Title: Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing.
Volume: 148
Issue: 20
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Publication
28847987 | J:317020
First Author: Akeno N
Year: 2017
Journal: Mol Cancer Ther
Title: TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response.
Volume: 16
Issue: 12
Pages: 2913-2926
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Publication
22342966 | J:315064
First Author: Katz SF
Year: 2012
Journal: Gastroenterology
Title: Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.
Volume: 142
Issue: 5
Pages: 1229-1239.e3
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Publication
20739667 | J:168357
First Author: Xu G
Year: 2010
Journal: Biol Reprod
Title: BAX and tumor suppressor TRP53 are important in regulating mutagenesis in spermatogenic cells in mice.
Volume: 83
Issue: 6
Pages: 979-87
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Publication
23606570 | J:231875
First Author: Albers J
Year: 2013
Journal: EMBO Mol Med
Title: Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice.
Volume: 5
Issue: 6
Pages: 949-64
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Publication
15658891 | J:96279
First Author: Kubota T
Year: 2005
Journal: Radiat Res
Title: Comparison of properties of spontaneous and radiation-induced mouse thymic lymphomas: role of Trp53 and radiation.
Volume: 163
Issue: 2
Pages: 159-64
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Publication
10956433 | J:64384
First Author: Wang B
Year: 2000
Journal: Radiat Res
Title: Adaptive response in embryogenesis. III. Relationship to radiation-induced apoptosis and Trp53 gene status.
Volume: 154
Issue: 3
Pages: 277-82
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Publication
24998851 | J:221256
First Author: Stodden GR
Year: 2015
Journal: Oncogene
Title: Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment.
Volume: 34
Issue: 19
Pages: 2471-82
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Publication
27126173 | J:241555
First Author: Guinot A
Year: 2016
Journal: J Pathol
Title: Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.
Volume: 239
Issue: 3
Pages: 365-73
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Publication
19176372 | J:144831
First Author: Moral M
Year: 2009
Journal: Cancer Res
Title: Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.
Volume: 69
Issue: 3
Pages: 1099-108
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Publication
15319471 | J:92444
First Author: Reilly KM
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.
Volume: 101
Issue: 35
Pages: 13008-13
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Publication
28620865 | J:309383
First Author: Kim J
Year: 2017
Journal: Histochem Cell Biol
Title: Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.
Volume: 148
Issue: 5
Pages: 489-501
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Publication
29107533 | J:249297
First Author: Pathania M
Year: 2017
Journal: Cancer Cell
Title: H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Volume: 32
Issue: 5
Pages: 684-700.e9
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Publication
14702042 | J:87501
First Author: Liu G
Year: 2004
Journal: Nat Genet
Title: Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice.
Volume: 36
Issue: 1
Pages: 63-8
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Publication
11326422 | J:68090
First Author: Funabashi H
Year: 2001
Journal: Exp Anim
Title: Establishment of a Tcrb and Trp53 genes deficient mouse strain as an animal model for spontaneous colorectal cancer.
Volume: 50
Issue: 1
Pages: 41-7
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Publication
34839833 | J:320386
First Author: Yun WB
Year: 2021
Journal: Lab Anim Res
Title: Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice.
Volume: 37
Issue: 1
Pages: 32
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Publication
25943777 | J:319107
First Author: Upton DH
Year: 2015
Journal: Horm Cancer
Title: Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors.
Volume: 6
Issue: 4
Pages: 142-52
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Publication
37053216 | J:334753
First Author: Epstein RJ
Year: 2023
Journal: PLoS One
Title: Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice.
Volume: 18
Issue: 4
Pages: e0284327
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Publication
15055301 | J:90351
 
First Author: French JE
Year: 2004
Journal: IARC Sci Publ
Title: Identification and characterization of potential human carcinogens using B6.129tm1Trp53 heterozygous null mice and loss of heterozygosity at the Trp53 locus.
Issue: 157
Pages: 271-87
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Publication
17118206 | J:117791
 
First Author: Chandrakanthan V
Year: 2006
Journal: Reprod Biol Endocrinol
Title: Effects of in vitro fertilization and embryo culture on TRP53 and Bax expression in B6 mouse embryos.
Volume: 4
Pages: 61
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Publication
33824284 | J:314022
First Author: Marruecos L
Year: 2021
Journal: Cell Death Dis
Title: Single loss of a Trp53 allele triggers an increased oxidative, DNA damage and cytokine inflammatory responses through deregulation of IκBα expression.
Volume: 12
Issue: 4
Pages: 359
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Publication
28686579 | J:269296
First Author: Gurley KE
Year: 2017
Journal: Cell Death Differ
Title: Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.
Volume: 24
Issue: 11
Pages: 1853-1860
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Publication
11159747 | J:67080
First Author: French JE
Year: 2001
Journal: Carcinogenesis
Title: Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent.
Volume: 22
Issue: 1
Pages: 99-106
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191506
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Trp53
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191506
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Trp53
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191506
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Trp53
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191506
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Trp53
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Trp53
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Trp53
Detected: true
Specimen Num: 6
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6185875
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191506
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Trp53
Detected: true
Specimen Num: 7
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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