|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 363 for Trp53bp1

<< First    < Previous  |  Next >    Last >>
0.021s
Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Detected: true
Specimen Num: 2
Publication
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Celeste A
Year: 2002
Journal: Science
Title: Genomic instability in mice lacking histone H2AX.
Volume: 296
Issue: 5569
Pages: 922-7
Publication
First Author: Jullien D
Year: 2002
Journal: J Cell Sci
Title: Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.
Volume: 115
Issue: Pt 1
Pages: 71-9
Publication
First Author: Datta B
Year: 1996
Journal: J Biol Chem
Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.
Volume: 271
Issue: 44
Pages: 27544-55
Publication
First Author: Ward IM
Year: 2003
Journal: Mol Cell Biol
Title: p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Volume: 23
Issue: 7
Pages: 2556-63
Publication
First Author: Ward IM
Year: 2004
Journal: J Cell Biol
Title: 53BP1 is required for class switch recombination.
Volume: 165
Issue: 4
Pages: 459-64
Publication
First Author: Manis JP
Year: 2004
Journal: Nat Immunol
Title: 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
Volume: 5
Issue: 5
Pages: 481-7
Publication
First Author: Bunting SF
Year: 2010
Journal: Cell
Title: 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Volume: 141
Issue: 2
Pages: 243-54
Publication
First Author: Hartlerode AJ
Year: 2012
Journal: PLoS One
Title: Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks.
Volume: 7
Issue: 11
Pages: e49211
Publication
First Author: Chapman JR
Year: 2013
Journal: Mol Cell
Title: RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
Volume: 49
Issue: 5
Pages: 858-71
Publication
First Author: Di Virgilio M
Year: 2013
Journal: Science
Title: Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Volume: 339
Issue: 6120
Pages: 711-5
Publication
First Author: Dong J
Year: 2015
Journal: Nature
Title: Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
Volume: 525
Issue: 7567
Pages: 134-139
Publication
First Author: Ramachandran S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.
Volume: 107
Issue: 2
Pages: 809-14
Publication
First Author: Saxe JP
Year: 2013
Journal: EMBO J
Title: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline.
Volume: 32
Issue: 13
Pages: 1869-85
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Wu J
Year: 2009
Journal: J Biol Chem
Title: PTIP regulates 53BP1 and SMC1 at the DNA damage sites.
Volume: 284
Issue: 27
Pages: 18078-84
Publication
First Author: Escribano-Díaz C
Year: 2013
Journal: Mol Cell
Title: A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Volume: 49
Issue: 5
Pages: 872-83
Publication
First Author: Zimmermann M
Year: 2013
Journal: Science
Title: 53BP1 regulates DSB repair using Rif1 to control 5' end resection.
Volume: 339
Issue: 6120
Pages: 700-4
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Akhter S
Year: 2004
Journal: Mol Cell Biol
Title: Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
Volume: 24
Issue: 23
Pages: 10448-55
Publication
First Author: Tkáč J
Year: 2016
Journal: Mol Cell
Title: HELB Is a Feedback Inhibitor of DNA End Resection.
Volume: 61
Issue: 3
Pages: 405-418
Publication
First Author: Pei H
Year: 2013
Journal: J Immunol
Title: The histone methyltransferase MMSET regulates class switch recombination.
Volume: 190
Issue: 2
Pages: 756-63
Publication
First Author: Kato Y
Year: 2015
Journal: Hum Mol Genet
Title: FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.
Volume: 24
Issue: 18
Pages: 5234-49
Publication
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
Publication
First Author: Noordermeer SM
Year: 2018
Journal: Nature
Title: The shieldin complex mediates 53BP1-dependent DNA repair.
Volume: 560
Issue: 7716
Pages: 117-121
Publication
First Author: Schotta G
Year: 2008
Journal: Genes Dev
Title: A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Volume: 22
Issue: 15
Pages: 2048-61
Publication      
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Lee Y
Year: 2009
Journal: Nat Neurosci
Title: The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.
Volume: 12
Issue: 8
Pages: 973-80
Publication
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
Publication
First Author: Goggolidou P
Year: 2014
Journal: Development
Title: ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.
Volume: 141
Issue: 20
Pages: 3966-77
Publication      
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for concur
Publication      
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for verily
Publication      
First Author: Wang K-W
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for lentil
Publication
First Author: Broering TJ
Year: 2014
Journal: J Cell Biol
Title: BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.
Volume: 205
Issue: 5
Pages: 663-75
Publication
First Author: Martínez P
Year: 2012
Journal: J Cell Biol
Title: 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
Volume: 197
Issue: 2
Pages: 283-300
Publication
First Author: Barlow JH
Year: 2013
Journal: Cell
Title: Identification of early replicating fragile sites that contribute to genome instability.
Volume: 152
Issue: 3
Pages: 620-32
Publication
First Author: Paiano J
Year: 2020
Journal: Nat Commun
Title: ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.
Volume: 11
Issue: 1
Pages: 857
Publication
First Author: Shinoda K
Year: 2021
Journal: Mol Cell
Title: The dystonia gene THAP1 controls DNA double-strand break repair choice.
Volume: 81
Issue: 12
Pages: 2611-2624.e10
Publication
First Author: Zong D
Year: 2019
Journal: Mol Cell
Title: BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Volume: 73
Issue: 6
Pages: 1267-1281.e7
Publication
First Author: Rybanska-Spaeder I
Year: 2014
Journal: PLoS One
Title: 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
Volume: 9
Issue: 9
Pages: e108731
Publication
First Author: Sfeir A
Year: 2012
Journal: Science
Title: Removal of shelterin reveals the telomere end-protection problem.
Volume: 336
Issue: 6081
Pages: 593-7
Publication
First Author: Buonomo SB
Year: 2009
Journal: J Cell Biol
Title: Mammalian Rif1 contributes to replication stress survival and homology-directed repair.
Volume: 187
Issue: 3
Pages: 385-98
Publication
First Author: Liu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.
Volume: 109
Issue: 10
Pages: 3903-8
Publication
First Author: Rocha PP
Year: 2016
Journal: Cell Rep
Title: A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.
Volume: 16
Issue: 1
Pages: 48-55
Publication
First Author: Rybanska-Spaeder I
Year: 2013
Journal: Mol Cancer Res
Title: 53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.
Volume: 11
Issue: 10
Pages: 1223-34
Publication
First Author: Fradet-Turcotte A
Year: 2013
Journal: Nature
Title: 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Volume: 499
Issue: 7456
Pages: 50-4
Publication
First Author: Sundaravinayagam D
Year: 2019
Journal: Cell Rep
Title: 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function.
Volume: 28
Issue: 6
Pages: 1389-1399.e6
Publication
First Author: Bothmer A
Year: 2010
Journal: J Exp Med
Title: 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.
Volume: 207
Issue: 4
Pages: 855-65
Publication
First Author: Li M
Year: 2016
Journal: EMBO Rep
Title: 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.
Volume: 17
Issue: 11
Pages: 1532-1541
Publication
First Author: Boulianne B
Year: 2017
Journal: Cell Rep
Title: Lineage-Specific Genes Are Prominent DNA Damage Hotspots during Leukemic Transformation of B Cell Precursors.
Volume: 18
Issue: 7
Pages: 1687-1698
Publication
First Author: Callén E
Year: 2009
Journal: Mol Cell
Title: Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Volume: 34
Issue: 3
Pages: 285-97
Publication
First Author: Ramiro AR
Year: 2006
Journal: Nature
Title: Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Volume: 440
Issue: 7080
Pages: 105-9
Publication    
First Author: Atkins A
Year: 2020
Journal: Elife
Title: SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.
Volume: 9
Publication
First Author: Callen E
Year: 2013
Journal: Cell
Title: 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Volume: 153
Issue: 6
Pages: 1266-80
Publication
First Author: Dimitrova N
Year: 2008
Journal: Nature
Title: 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Volume: 456
Issue: 7221
Pages: 524-8
Publication
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
Publication
First Author: Sin HS
Year: 2012
Journal: Genes Dev
Title: RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.
Volume: 26
Issue: 24
Pages: 2737-48
Publication
First Author: Jankovic M
Year: 2013
Journal: Mol Cell
Title: 53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma.
Volume: 49
Issue: 4
Pages: 623-31
Publication
First Author: Nacson J
Year: 2018
Journal: Cell Rep
Title: BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Volume: 24
Issue: 13
Pages: 3513-3527.e7
Publication
First Author: Polato F
Year: 2014
Journal: J Exp Med
Title: CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Volume: 211
Issue: 6
Pages: 1027-36
Publication
First Author: Callén E
Year: 2007
Journal: Cell
Title: ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
Volume: 130
Issue: 1
Pages: 63-75
Publication
First Author: Minter-Dykhouse K
Year: 2008
Journal: J Cell Biol
Title: Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.
Volume: 181
Issue: 5
Pages: 727-35
Publication
First Author: Sasanuma H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Volume: 115
Issue: 45
Pages: E10642-E10651
Publication
First Author: Patel DS
Year: 2017
Journal: J Cell Biol
Title: BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.
Volume: 216
Issue: 11
Pages: 3521-3534
Publication
First Author: Su D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice.
Volume: 114
Issue: 44
Pages: E9328-E9337
Publication  
First Author: Liu X
Year: 2017
Journal: Nat Commun
Title: PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.
Volume: 8
Pages: 13816
Publication
First Author: Bothmer A
Year: 2013
Journal: J Exp Med
Title: Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.
Volume: 210
Issue: 1
Pages: 115-23
Publication
First Author: Li C
Year: 2018
Journal: Nat Commun
Title: The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining.
Volume: 9
Issue: 1
Pages: 1006
Publication
First Author: Martínez P
Year: 2014
Journal: Aging Cell
Title: Essential role for the TRF2 telomere protein in adult skin homeostasis.
Volume: 13
Issue: 4
Pages: 656-68