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Search results 1 to 100 out of 488 for Trpa1

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0.019s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7388609
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7388630
Age: postnatal day 30
Image: 4D TRPA1 Control
Note: Lower level of expression compared to cervical and thoracic DRG.
Specimen Label: 4D TRPA1 Control
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7388609
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3667828
Stage: TS28
Assay Id: MGI:7388630
Age: postnatal day 30
Image: 4D TRPA1 Tlx3 CKO
Note: No expression in lumbar DRG at P30.
Specimen Label: 4D TRPA1 Tlx3 CKO
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:7484577
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7484629
Age: postnatal adult
Specimen Label: 5d TRPA1
Detected: true
Specimen Num: 3
Publication
First Author: del Camino D
Year: 2010
Journal: J Neurosci
Title: TRPA1 contributes to cold hypersensitivity.
Volume: 30
Issue: 45
Pages: 15165-74
GXD Expression    
Probe: MGI:7484577
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7484629
Age: postnatal adult
Specimen Label: 5a TRPA1 Control
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7484577
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7484629
Age: postnatal adult
Note: Proportion of expressing neurons signficantly decreased compared to control.
Specimen Label: 5a TRPA1 PN-ZB20KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7484583
Assay Type: RNA in situ
Annotation Date: 2023-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7484639
Age: postnatal adult
Specimen Label: 4 TRPA1 Control
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7484583
Assay Type: RNA in situ
Annotation Date: 2023-05-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7484639
Age: postnatal adult
Note: Percentage of expressing neurons significantly decreased compared to control.
Specimen Label: 4 TRPA1 PN-ZB20KO
Detected: true
Specimen Num: 2
Publication
First Author: Takahashi N
Year: 2011
Journal: Nat Chem Biol
Title: TRPA1 underlies a sensing mechanism for O2.
Volume: 7
Issue: 10
Pages: 701-11
Publication
First Author: Kwan KY
Year: 2009
Journal: J Neurosci
Title: TRPA1 modulates mechanotransduction in cutaneous sensory neurons.
Volume: 29
Issue: 15
Pages: 4808-19
Publication  
First Author: Sawada Y
Year: 2007
Journal: Brain Res
Title: Cold sensitivity of recombinant TRPA1 channels.
Volume: 1160
Pages: 39-46
Publication  
First Author: Hoebart C
Year: 2023
Journal: Int J Mol Sci
Title: TRPA1 as Target in Myocardial Infarction.
Volume: 24
Issue: 3
Publication
First Author: Nagatomo K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels.
Volume: 105
Issue: 45
Pages: 17373-8
Publication
First Author: Conklin DJ
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: TRPA1 channel contributes to myocardial ischemia-reperfusion injury.
Volume: 316
Issue: 4
Pages: H889-H899
Publication  
First Author: Zhou Y
Year: 2013
Journal: Nat Commun
Title: Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity.
Volume: 4
Pages: 2399
Publication      
First Author: Mäki-Opas I
Year: 2023
Journal: J Invest Dermatol
Title: TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene.
Publication    
First Author: Thakore P
Year: 2021
Journal: Elife
Title: Brain endothelial cell TRPA1 channels initiate neurovascular coupling.
Volume: 10
Publication  
First Author: Wang Q
Year: 2020
Journal: Atherosclerosis
Title: TRPA1 regulates macrophages phenotype plasticity and atherosclerosis progression.
Volume: 301
Pages: 44-53
Publication
First Author: Wilson SR
Year: 2011
Journal: Nat Neurosci
Title: TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Volume: 14
Issue: 5
Pages: 595-602
Publication
First Author: Escalera J
Year: 2008
Journal: J Biol Chem
Title: TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.
Volume: 283
Issue: 35
Pages: 24136-44
Publication
First Author: Wilson SR
Year: 2013
Journal: J Neurosci
Title: The ion channel TRPA1 is required for chronic itch.
Volume: 33
Issue: 22
Pages: 9283-94
Publication
First Author: Schmidt M
Year: 2009
Journal: Neuron
Title: Nociceptive signals induce trafficking of TRPA1 to the plasma membrane.
Volume: 64
Issue: 4
Pages: 498-509
Publication
First Author: Andrade EL
Year: 2008
Journal: Neuroscience
Title: Pronociceptive response elicited by TRPA1 receptor activation in mice.
Volume: 152
Issue: 2
Pages: 511-20
Publication  
First Author: Conklin DJ
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein.
Volume: 324
Pages: 61-72
Publication
First Author: Andersson DA
Year: 2015
Journal: J Biol Chem
Title: Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.
Volume: 290
Issue: 24
Pages: 15185-96
Publication
First Author: Zappia KJ
Year: 2016
Journal: PLoS One
Title: Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes.
Volume: 11
Issue: 3
Pages: e0151602
Publication
First Author: Miyamoto T
Year: 2009
Journal: PLoS One
Title: TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.
Volume: 4
Issue: 10
Pages: e7596
Publication
First Author: De Logu F
Year: 2016
Journal: Cancer Res
Title: TRPA1 Mediates Aromatase Inhibitor-Evoked Pain by the Aromatase Substrate Androstenedione.
Volume: 76
Issue: 23
Pages: 7024-7035
Publication
First Author: Babes A
Year: 2016
Journal: J Neurosci
Title: Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.
Volume: 36
Issue: 19
Pages: 5264-78
Publication
First Author: Ma S
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Knockout of TRPA1 exacerbates angiotensin II-induced kidney injury.
Volume: 317
Issue: 3
Pages: F623-F631
Publication
First Author: Matsuo T
Year: 2021
Journal: Nat Commun
Title: Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation.
Volume: 12
Issue: 1
Pages: 2074
Publication
First Author: Suzuki H
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.
Volume: 307
Issue: 4
Pages: C384-94
Publication
First Author: Moilanen LJ
Year: 2015
Journal: Osteoarthritis Cartilage
Title: Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis.
Volume: 23
Issue: 11
Pages: 2017-26
Publication    
First Author: Pires PW
Year: 2018
Journal: Elife
Title: Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke.
Volume: 7
Publication
First Author: Bautista DM
Year: 2006
Journal: Cell
Title: TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Volume: 124
Issue: 6
Pages: 1269-82
Publication
First Author: Lin King JV
Year: 2019
Journal: Cell
Title: A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain.
Volume: 178
Issue: 6
Pages: 1362-1374.e16
Publication  
First Author: Yonemitsu T
Year: 2013
Journal: Sci Rep
Title: TRPA1 detects environmental chemicals and induces avoidance behavior and arousal from sleep.
Volume: 3
Pages: 3100
Publication
First Author: Shigetomi E
Year: 2011
Journal: Nat Neurosci
Title: TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3.
Volume: 15
Issue: 1
Pages: 70-80
Publication  
First Author: Andersson DA
Year: 2011
Journal: Nat Commun
Title: TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
Volume: 2
Pages: 551
Publication    
First Author: Startek JB
Year: 2019
Journal: Elife
Title: Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol.
Volume: 8
Publication
First Author: Trevisan G
Year: 2013
Journal: Cancer Res
Title: Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade.
Volume: 73
Issue: 10
Pages: 3120-31
Publication
First Author: Fujita F
Year: 2008
Journal: J Clin Invest
Title: Intracellular alkalization causes pain sensation through activation of TRPA1 in mice.
Volume: 118
Issue: 12
Pages: 4049-57
Publication
First Author: Bessac BF
Year: 2008
Journal: J Clin Invest
Title: TRPA1 is a major oxidant sensor in murine airway sensory neurons.
Volume: 118
Issue: 5
Pages: 1899-910
Publication
First Author: Moldenhauer H
Year: 2014
Journal: PLoS One
Title: The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole.
Volume: 9
Issue: 9
Pages: e106776
Publication  
First Author: Miura S
Year: 2013
Journal: Mol Pain
Title: Involvement of TRPA1 activation in acute pain induced by cadmium in mice.
Volume: 9
Pages: 7
Publication  
First Author: Wilzopolski J
Year: 2021
Journal: Biomolecules
Title: TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch.
Volume: 11
Issue: 8
Publication  
First Author: Meseguer V
Year: 2014
Journal: Nat Commun
Title: TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.
Volume: 5
Pages: 3125
Publication
First Author: Michot B
Year: 2018
Journal: Sci Rep
Title: TRPM8 and TRPA1 do not contribute to dental pulp sensitivity to cold.
Volume: 8
Issue: 1
Pages: 13198
Publication  
First Author: Lemon CH
Year: 2019
Journal: eNeuro
Title: The TRPA1 Ion Channel Contributes to Sensory-Guided Avoidance of Menthol in Mice.
Volume: 6
Issue: 6
Publication
First Author: Andrei SR
Year: 2017
Journal: Channels (Austin)
Title: TRPA1 ion channel stimulation enhances cardiomyocyte contractile function via a CaMKII-dependent pathway.
Volume: 11
Issue: 6
Pages: 587-603
Publication
First Author: Kwan KY
Year: 2006
Journal: Neuron
Title: TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction.
Volume: 50
Issue: 2
Pages: 277-89
Publication  
First Author: Miyake T
Year: 2016
Journal: Nat Commun
Title: Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS.
Volume: 7
Pages: 12840
Publication
First Author: Karashima Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: TRPA1 acts as a cold sensor in vitro and in vivo.
Volume: 106
Issue: 4
Pages: 1273-8
Publication
First Author: Shang S
Year: 2016
Journal: J Cell Biol
Title: Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons.
Volume: 215
Issue: 3
Pages: 369-381
Publication  
First Author: Moilanen LJ
Year: 2012
Journal: Sci Rep
Title: TRPA1 contributes to the acute inflammatory response and mediates carrageenan-induced paw edema in the mouse.
Volume: 2
Pages: 380
Publication
First Author: Corey DP
Year: 2004
Journal: Nature
Title: TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.
Volume: 432
Issue: 7018
Pages: 723-30
Publication
First Author: Han Q
Year: 2018
Journal: Neuron
Title: miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.
Volume: 99
Issue: 3
Pages: 449-463.e6
Publication  
First Author: Aubdool AA
Year: 2014
Journal: Nat Commun
Title: TRPA1 is essential for the vascular response to environmental cold exposure.
Volume: 5
Pages: 5732
Publication  
First Author: Zappia KJ
Year: 2017
Journal: eNeuro
Title: Sensory Neuron-Specific Deletion of TRPA1 Results in Mechanical Cutaneous Sensory Deficits.
Volume: 4
Issue: 1
Publication
First Author: Hoffmann T
Year: 2013
Journal: Eur J Pain
Title: TRPA1 and TRPV1 are differentially involved in heat nociception of mice.
Volume: 17
Issue: 10
Pages: 1472-82
Publication
First Author: Salas MM
Year: 2009
Journal: Eur J Neurosci
Title: TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1.
Volume: 29
Issue: 8
Pages: 1568-78
Publication  
First Author: Griggs RB
Year: 2017
Journal: Front Neurosci
Title: Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation.
Volume: 11
Pages: 679
Publication
First Author: Patil MJ
Year: 2020
Journal: FASEB J
Title: Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association.
Volume: 34
Issue: 1
Pages: 287-302
Publication
First Author: Kakae M
Year: 2023
Journal: Sci Adv
Title: The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production.
Volume: 9
Issue: 29
Pages: eadh0102
Publication
First Author: Fajardo O
Year: 2008
Journal: J Neurosci
Title: TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.
Volume: 28
Issue: 31
Pages: 7863-75
Publication  
First Author: Frutos-Rincón L
Year: 2023
Journal: Int J Mol Sci
Title: The Contribution of TRPA1 to Corneal Thermosensitivity and Blink Regulation in Young and Aged Mice.
Volume: 24
Issue: 16
Publication
First Author: Kemény Á
Year: 2018
Journal: J Invest Dermatol
Title: TRPA1 Acts in a Protective Manner in Imiquimod-Induced Psoriasiform Dermatitis in Mice.
Volume: 138
Issue: 8
Pages: 1774-1784
Publication  
First Author: Kurhanewicz N
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: TRPA1 mediates changes in heart rate variability and cardiac mechanical function in mice exposed to acrolein.
Volume: 324
Pages: 51-60
Publication  
First Author: Hajna Z
Year: 2020
Journal: Int J Mol Sci
Title: Complex Regulatory Role of the TRPA1 Receptor in Acute and Chronic Airway Inflammation Mouse Models.
Volume: 21
Issue: 11
Publication
First Author: Andrè E
Year: 2008
Journal: J Clin Invest
Title: Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Volume: 118
Issue: 7
Pages: 2574-82
Publication  
First Author: Dalenogare DP
Year: 2020
Journal: Exp Neurol
Title: TRPA1 activation mediates nociception behaviors in a mouse model of relapsing-remitting experimental autoimmune encephalomyelitis.
Volume: 328
Pages: 113241
Publication
First Author: Uchiyama M
Year: 2020
Journal: Curr Biol
Title: O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses.
Volume: 30
Issue: 17
Pages: 3378-3396.e7
Publication
First Author: Sullivan MN
Year: 2015
Journal: Sci Signal
Title: Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Volume: 8
Issue: 358
Pages: ra2
Publication
First Author: Brierley SM
Year: 2009
Journal: Gastroenterology
Title: The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.
Volume: 137
Issue: 6
Pages: 2084-2095.e3
Publication
First Author: Liu L
Year: 2023
Journal: FASEB J
Title: TRPA1 protects mice from pathogenic Citrobacter rodentium infection via maintaining the colonic epithelial barrier function.
Volume: 37
Issue: 2
Pages: e22739
Publication
First Author: Cho HJ
Year: 2014
Journal: Cell Tissue Res
Title: Identification of enteroendocrine cells that express TRPA1 channels in the mouse intestine.
Volume: 356
Issue: 1
Pages: 77-82
Publication
First Author: De Logu F
Year: 2017
Journal: Nat Commun
Title: Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
Volume: 8
Issue: 1
Pages: 1887
Publication
First Author: Wang Y
Year: 2018
Journal: Nat Commun
Title: Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Volume: 9
Issue: 1
Pages: 2041
Publication
First Author: Shigetomi E
Year: 2013
Journal: J Neurosci
Title: TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release.
Volume: 33
Issue: 24
Pages: 10143-53
Publication
First Author: Pozsgai G
Year: 2010
Journal: Cardiovasc Res
Title: Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.
Volume: 87
Issue: 4
Pages: 760-8
Publication
First Author: Brierley SM
Year: 2011
Journal: J Physiol
Title: TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.
Volume: 589
Issue: Pt 14
Pages: 3575-93
Publication  
First Author: Ko HK
Year: 2020
Journal: Front Physiol
Title: Lung Epithelial TRPA1 Mediates Lipopolysaccharide-Induced Lung Inflammation in Bronchial Epithelial Cells and Mice.
Volume: 11
Pages: 596314
Publication
First Author: Trevisan G
Year: 2016
Journal: Brain
Title: TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress.
Volume: 139
Issue: Pt 5
Pages: 1361-77
Publication
First Author: Zhang Q
Year: 2023
Journal: Cell Rep
Title: hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA.
Volume: 42
Issue: 11
Pages: 113401
Publication  
First Author: Memon T
Year: 2017
Journal: Neuroscience
Title: TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons.
Volume: 353
Pages: 76-86
Publication  
First Author: Dombi Á
Year: 2021
Journal: Int J Mol Sci
Title: Dimethyl Trisulfide Diminishes Traumatic Neuropathic Pain Acting on TRPA1 Receptors in Mice.
Volume: 22
Issue: 7
Publication
First Author: Lanosa MJ
Year: 2010
Journal: Toxicol Sci
Title: Role of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene.
Volume: 115
Issue: 2
Pages: 589-95
Publication
First Author: Jabba S
Year: 2014
Journal: Neuron
Title: Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
Volume: 82
Issue: 5
Pages: 1017-31
Publication
First Author: Malsch P
Year: 2014
Journal: J Neurosci
Title: Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.
Volume: 34
Issue: 30
Pages: 9845-56
Publication
First Author: Sinha S
Year: 2015
Journal: PLoS One
Title: Propofol causes vasodilation in vivo via TRPA1 ion channels: role of nitric oxide and BKCa channels.
Volume: 10
Issue: 4
Pages: e0122189
Publication
First Author: Li Puma S
Year: 2019
Journal: J Cell Mol Med
Title: TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal.
Volume: 23
Issue: 3
Pages: 1976-1986