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Search results 1 to 100 out of 352 for Trpa1

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0.051s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Takahashi S
Year: 2019
Journal: Sci Rep
Title: Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development.
Volume: 9
Issue: 1
Pages: 8625
Allele
Name: transient receptor potential cation channel, subfamily A, member 1; targeted mutation 1, Takaharu Okada
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
Publication categories: ProxyCollection
Publication
First Author: del Camino D
Year: 2010
Journal: J Neurosci
Title: TRPA1 contributes to cold hypersensitivity.
Volume: 30
Issue: 45
Pages: 15165-74
Publication  
First Author: Sawada Y
Year: 2007
Journal: Brain Res
Title: Cold sensitivity of recombinant TRPA1 channels.
Volume: 1160
Pages: 39-46
Publication
First Author: Kwan KY
Year: 2009
Journal: J Neurosci
Title: TRPA1 modulates mechanotransduction in cutaneous sensory neurons.
Volume: 29
Issue: 15
Pages: 4808-19
Publication
First Author: Nagatomo K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels.
Volume: 105
Issue: 45
Pages: 17373-8
Publication
First Author: Conklin DJ
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: TRPA1 channel contributes to myocardial ischemia-reperfusion injury.
Volume: 316
Issue: 4
Pages: H889-H899
Publication
First Author: Wilson SR
Year: 2011
Journal: Nat Neurosci
Title: TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Volume: 14
Issue: 5
Pages: 595-602
Publication
First Author: Escalera J
Year: 2008
Journal: J Biol Chem
Title: TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.
Volume: 283
Issue: 35
Pages: 24136-44
Publication
First Author: Schmidt M
Year: 2009
Journal: Neuron
Title: Nociceptive signals induce trafficking of TRPA1 to the plasma membrane.
Volume: 64
Issue: 4
Pages: 498-509
Publication
First Author: Wilson SR
Year: 2013
Journal: J Neurosci
Title: The ion channel TRPA1 is required for chronic itch.
Volume: 33
Issue: 22
Pages: 9283-94
Publication
First Author: Andrade EL
Year: 2008
Journal: Neuroscience
Title: Pronociceptive response elicited by TRPA1 receptor activation in mice.
Volume: 152
Issue: 2
Pages: 511-20
Publication  
First Author: Conklin DJ
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein.
Volume: 324
Pages: 61-72
Publication
First Author: Andersson DA
Year: 2015
Journal: J Biol Chem
Title: Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.
Volume: 290
Issue: 24
Pages: 15185-96
Publication
First Author: Zappia KJ
Year: 2016
Journal: PLoS One
Title: Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes.
Volume: 11
Issue: 3
Pages: e0151602
Publication
First Author: Miyamoto T
Year: 2009
Journal: PLoS One
Title: TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.
Volume: 4
Issue: 10
Pages: e7596
Publication
First Author: De Logu F
Year: 2016
Journal: Cancer Res
Title: TRPA1 Mediates Aromatase Inhibitor-Evoked Pain by the Aromatase Substrate Androstenedione.
Volume: 76
Issue: 23
Pages: 7024-7035
Publication
First Author: Ma S
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Knockout of TRPA1 exacerbates angiotensin II-induced kidney injury.
Volume: 317
Issue: 3
Pages: F623-F631
Publication
First Author: Babes A
Year: 2016
Journal: J Neurosci
Title: Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.
Volume: 36
Issue: 19
Pages: 5264-78
Publication
First Author: Suzuki H
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.
Volume: 307
Issue: 4
Pages: C384-94
Publication
First Author: Bautista DM
Year: 2006
Journal: Cell
Title: TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Volume: 124
Issue: 6
Pages: 1269-82
Publication
First Author: Lin King JV
Year: 2019
Journal: Cell
Title: A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain.
Volume: 178
Issue: 6
Pages: 1362-1374.e16
Publication
First Author: Shigetomi E
Year: 2011
Journal: Nat Neurosci
Title: TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3.
Volume: 15
Issue: 1
Pages: 70-80
Publication  
First Author: Andersson DA
Year: 2011
Journal: Nat Commun
Title: TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
Volume: 2
Pages: 551
Publication  
First Author: Yonemitsu T
Year: 2013
Journal: Sci Rep
Title: TRPA1 detects environmental chemicals and induces avoidance behavior and arousal from sleep.
Volume: 3
Pages: 3100
Publication
First Author: Matsuo T
Year: 2021
Journal: Nat Commun
Title: Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation.
Volume: 12
Issue: 1
Pages: 2074
Publication
First Author: Trevisan G
Year: 2013
Journal: Cancer Res
Title: Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade.
Volume: 73
Issue: 10
Pages: 3120-31
Publication
First Author: Fujita F
Year: 2008
Journal: J Clin Invest
Title: Intracellular alkalization causes pain sensation through activation of TRPA1 in mice.
Volume: 118
Issue: 12
Pages: 4049-57
Publication
First Author: Bessac BF
Year: 2008
Journal: J Clin Invest
Title: TRPA1 is a major oxidant sensor in murine airway sensory neurons.
Volume: 118
Issue: 5
Pages: 1899-910
Publication
First Author: Moldenhauer H
Year: 2014
Journal: PLoS One
Title: The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole.
Volume: 9
Issue: 9
Pages: e106776
Publication  
First Author: Zappia KJ
Year: 2017
Journal: eNeuro
Title: Sensory Neuron-Specific Deletion of TRPA1 Results in Mechanical Cutaneous Sensory Deficits.
Volume: 4
Issue: 1
Publication  
First Author: Griggs RB
Year: 2017
Journal: Front Neurosci
Title: Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation.
Volume: 11
Pages: 679
Publication  
First Author: Lemon CH
Year: 2019
Journal: eNeuro
Title: The TRPA1 Ion Channel Contributes to Sensory-Guided Avoidance of Menthol in Mice.
Volume: 6
Issue: 6
Publication
First Author: Karashima Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: TRPA1 acts as a cold sensor in vitro and in vivo.
Volume: 106
Issue: 4
Pages: 1273-8
Publication
First Author: Kwan KY
Year: 2006
Journal: Neuron
Title: TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction.
Volume: 50
Issue: 2
Pages: 277-89
Publication  
First Author: Miyake T
Year: 2016
Journal: Nat Commun
Title: Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS.
Volume: 7
Pages: 12840
Publication
First Author: Corey DP
Year: 2004
Journal: Nature
Title: TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.
Volume: 432
Issue: 7018
Pages: 723-30
Publication
First Author: Han Q
Year: 2018
Journal: Neuron
Title: miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.
Volume: 99
Issue: 3
Pages: 449-463.e6
Publication  
First Author: Aubdool AA
Year: 2014
Journal: Nat Commun
Title: TRPA1 is essential for the vascular response to environmental cold exposure.
Volume: 5
Pages: 5732
Publication
First Author: Salas MM
Year: 2009
Journal: Eur J Neurosci
Title: TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1.
Volume: 29
Issue: 8
Pages: 1568-78
Publication
First Author: Patil MJ
Year: 2020
Journal: FASEB J
Title: Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association.
Volume: 34
Issue: 1
Pages: 287-302
Publication  
First Author: Hajna Z
Year: 2020
Journal: Int J Mol Sci
Title: Complex Regulatory Role of the TRPA1 Receptor in Acute and Chronic Airway Inflammation Mouse Models.
Volume: 21
Issue: 11
Publication
First Author: Sullivan MN
Year: 2015
Journal: Sci Signal
Title: Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Volume: 8
Issue: 358
Pages: ra2
Publication
First Author: Fajardo O
Year: 2008
Journal: J Neurosci
Title: TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.
Volume: 28
Issue: 31
Pages: 7863-75
Publication
First Author: Brierley SM
Year: 2009
Journal: Gastroenterology
Title: The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.
Volume: 137
Issue: 6
Pages: 2084-2095.e3
Publication  
First Author: Kurhanewicz N
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: TRPA1 mediates changes in heart rate variability and cardiac mechanical function in mice exposed to acrolein.
Volume: 324
Pages: 51-60
Publication  
First Author: Dalenogare DP
Year: 2020
Journal: Exp Neurol
Title: TRPA1 activation mediates nociception behaviors in a mouse model of relapsing-remitting experimental autoimmune encephalomyelitis.
Volume: 328
Pages: 113241
Publication
First Author: Andrè E
Year: 2008
Journal: J Clin Invest
Title: Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Volume: 118
Issue: 7
Pages: 2574-82
Publication
First Author: De Logu F
Year: 2017
Journal: Nat Commun
Title: Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
Volume: 8
Issue: 1
Pages: 1887
Publication
First Author: Wang Y
Year: 2018
Journal: Nat Commun
Title: Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Volume: 9
Issue: 1
Pages: 2041
Publication
First Author: Shigetomi E
Year: 2013
Journal: J Neurosci
Title: TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release.
Volume: 33
Issue: 24
Pages: 10143-53
Publication
First Author: Pozsgai G
Year: 2010
Journal: Cardiovasc Res
Title: Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.
Volume: 87
Issue: 4
Pages: 760-8
Publication
First Author: Brierley SM
Year: 2011
Journal: J Physiol
Title: TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.
Volume: 589
Issue: Pt 14
Pages: 3575-93
Publication  
First Author: Memon T
Year: 2017
Journal: Neuroscience
Title: TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons.
Volume: 353
Pages: 76-86
Publication
First Author: Jabba S
Year: 2014
Journal: Neuron
Title: Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
Volume: 82
Issue: 5
Pages: 1017-31
Publication
First Author: Lanosa MJ
Year: 2010
Journal: Toxicol Sci
Title: Role of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene.
Volume: 115
Issue: 2
Pages: 589-95
Publication
First Author: Malsch P
Year: 2014
Journal: J Neurosci
Title: Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.
Volume: 34
Issue: 30
Pages: 9845-56
Publication  
First Author: Xu M
Year: 2019
Journal: Oxid Med Cell Longev
Title: TRPV1 and TRPA1 in Lung Inflammation and Airway Hyperresponsiveness Induced by Fine Particulate Matter (PM2.5).
Volume: 2019
Pages: 7450151
Publication
First Author: Sinha S
Year: 2015
Journal: PLoS One
Title: Propofol causes vasodilation in vivo via TRPA1 ion channels: role of nitric oxide and BKCa channels.
Volume: 10
Issue: 4
Pages: e0122189
Publication
First Author: Sinharoy P
Year: 2017
Journal: PLoS One
Title: TRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries.
Volume: 12
Issue: 6
Pages: e0180106
Publication
First Author: Okada Y
Year: 2014
Journal: Lab Invest
Title: TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma.
Volume: 94
Issue: 9
Pages: 1030-41
Publication
First Author: De Logu F
Year: 2019
Journal: J Clin Invest
Title: Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice.
Volume: 129
Issue: 12
Pages: 5424-5441
Publication
First Author: Gregus AM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.
Volume: 109
Issue: 17
Pages: 6721-6
Publication
First Author: Andersson DA
Year: 2012
Journal: PLoS One
Title: TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.
Volume: 7
Issue: 10
Pages: e46917
Publication
First Author: Boiko N
Year: 2017
Journal: PLoS One
Title: TrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids.
Volume: 12
Issue: 10
Pages: e0186888
Publication
First Author: Xiao B
Year: 2008
Journal: J Neurosci
Title: Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
Volume: 28
Issue: 39
Pages: 9640-51
Publication  
First Author: Hiyama H
Year: 2018
Journal: Mol Pain
Title: TRPA1 sensitization during diabetic vascular impairment contributes to cold hypersensitivity in a mouse model of painful diabetic peripheral neuropathy.
Volume: 14
Pages: 1744806918789812
Publication
First Author: Wang S
Year: 2018
Journal: Diabetes
Title: Negative Regulation of TRPA1 by AMPK in Primary Sensory Neurons as a Potential Mechanism of Painful Diabetic Neuropathy.
Volume: 67
Issue: 1
Pages: 98-109
Publication
First Author: Taylor-Clark TE
Year: 2008
Journal: J Physiol
Title: Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal.
Volume: 586
Issue: 14
Pages: 3447-59
Publication
First Author: Eberhardt M
Year: 2017
Journal: PLoS One
Title: TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons.
Volume: 12
Issue: 11
Pages: e0188008
Publication  
First Author: Stanford KR
Year: 2019
Journal: Brain Res
Title: Antimycin A-induced mitochondrial dysfunction activates vagal sensory neurons via ROS-dependent activation of TRPA1 and ROS-independent activation of TRPV1.
Volume: 1715
Pages: 94-105
Publication
First Author: Akopian AN
Year: 2007
Journal: J Physiol
Title: Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization.
Volume: 583
Issue: Pt 1
Pages: 175-93
Publication  
First Author: Trevisan G
Year: 2014
Journal: Free Radic Biol Med
Title: TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout.
Volume: 72
Pages: 200-9
Publication  
First Author: Zheng X
Year: 2019
Journal: Mol Pain
Title: ETAR and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: A molecular mechanism of ET-1-induced mechanical hyperalgesia.
Volume: 15
Pages: 1744806919842473
Publication  
First Author: Kameda T
Year: 2019
Journal: Int J Mol Sci
Title: Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling.
Volume: 20
Issue: 7
Publication  
First Author: Huang D
Year: 2012
Journal: Mol Pain
Title: Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura.
Volume: 8
Pages: 66
Publication  
First Author: Cun-Jin S
Year: 2019
Journal: Mol Pain
Title: X-ray induces mechanical and heat allodynia in mouse via TRPA1 and TRPV1 activation.
Volume: 15
Pages: 1744806919849201
Publication
First Author: Cheng RX
Year: 2019
Journal: Theranostics
Title: The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes.
Volume: 9
Issue: 15
Pages: 4287-4307
Publication
First Author: Kichko TI
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.
Volume: 309
Issue: 8
Pages: L812-20
Publication  
First Author: Elitt CM
Year: 2008
Journal: Brain Res
Title: Overexpression of artemin in the tongue increases expression of TRPV1 and TRPA1 in trigeminal afferents and causes oral sensitivity to capsaicin and mustard oil.
Volume: 1230
Pages: 80-90
Publication      
First Author: Corey D
Year: 2011
Journal: MGI Direct Data Submission
Title: Generation of a conditional allele of Trpa1
Publication
First Author: Elitt CM
Year: 2006
Journal: J Neurosci
Title: Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold.
Volume: 26
Issue: 33
Pages: 8578-87
Publication      
First Author: Liu Q
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for petrified.
Publication
First Author: Macpherson LJ
Year: 2007
Journal: J Neurosci
Title: An ion channel essential for sensing chemical damage.
Volume: 27
Issue: 42
Pages: 11412-5
Publication
First Author: Kheradpezhouh E
Year: 2020
Journal: Cell Rep
Title: Enhanced Sensory Coding in Mouse Vibrissal and Visual Cortex through TRPA1.
Volume: 32
Issue: 3
Pages: 107935
Publication  
First Author: Fusi C
Year: 2014
Journal: Nat Commun
Title: Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Volume: 5
Pages: 5736
Publication
First Author: Talavera K
Year: 2009
Journal: Nat Neurosci
Title: Nicotine activates the chemosensory cation channel TRPA1.
Volume: 12
Issue: 10
Pages: 1293-9
Publication
First Author: Hamilton NB
Year: 2016
Journal: Nature
Title: Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia.
Volume: 529
Issue: 7587
Pages: 523-7
Publication
First Author: Fischer MJ
Year: 2015
Journal: PLoS One
Title: Formalin evokes calcium transients from the endoplasmatic reticulum.
Volume: 10
Issue: 4
Pages: e0123762
Publication
First Author: Nagata K
Year: 2005
Journal: J Neurosci
Title: Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Volume: 25
Issue: 16
Pages: 4052-61
Publication
First Author: Emery EC
Year: 2015
Journal: Diabetes
Title: Stimulation of GLP-1 secretion downstream of the ligand-gated ion channel TRPA1.
Volume: 64
Issue: 4
Pages: 1202-10
Publication  
First Author: Yang Y
Year: 2019
Journal: JCI Insight
Title: TRPA1-expressing lamina propria mesenchymal cells regulate colonic motility.
Volume: 4
Issue: 9
Publication
First Author: Bessac BF
Year: 2009
Journal: FASEB J
Title: Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases.
Volume: 23
Issue: 4
Pages: 1102-14
Publication
First Author: Materazzi S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1.
Volume: 105
Issue: 33
Pages: 12045-50
Publication
First Author: Kun J
Year: 2014
Journal: PLoS One
Title: Upregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective roles.
Volume: 9
Issue: 9
Pages: e108164
Publication
First Author: Cattaruzza F
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
Volume: 304
Issue: 11
Pages: G1002-12