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Search results 1 to 100 out of 245 for Trpm1

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0.053s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: The TRPM subfamily of mammalian TRP channels includes TRPM1, which is required for the photoresponse in retinal ON-bipolar cells []. In conditions of darkness, glutamate is released from photoreceptors, activating the metabotropic glutamate receptor 6 on retinal ON bipolar cells. This activates the G protein G(o), which then closes TRPM1 channels, leading to hyperpolarisation of the cells []. Mutations in TRPM1 can cause congenital stationary night blindness [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Xu Y
Year: 2012
Journal: J Neurophysiol
Title: mGluR6 deletion renders the TRPM1 channel in retina inactive.
Volume: 107
Issue: 3
Pages: 948-57
Publication
First Author: van Genderen MM
Year: 2009
Journal: Am J Hum Genet
Title: Mutations in TRPM1 are a common cause of complete congenital stationary night blindness.
Volume: 85
Issue: 5
Pages: 730-6
Publication
First Author: Li Z
Year: 2009
Journal: Am J Hum Genet
Title: Recessive mutations of the gene TRPM1 abrogate ON bipolar cell function and cause complete congenital stationary night blindness in humans.
Volume: 85
Issue: 5
Pages: 711-9
Publication
First Author: Oancea E
Year: 2009
Journal: Sci Signal
Title: TRPM1 forms ion channels associated with melanin content in melanocytes.
Volume: 2
Issue: 70
Pages: ra21
Publication
First Author: Peachey NS
Year: 2012
Journal: J Neurophysiol
Title: Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.
Volume: 108
Issue: 9
Pages: 2442-51
Publication  
First Author: Agosto MA
Year: 2018
Journal: eNeuro
Title: A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells.
Volume: 5
Issue: 3
Publication
First Author: Varin J
Year: 2020
Journal: PLoS One
Title: Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy.
Volume: 15
Issue: 4
Pages: e0231750
Publication
First Author: Morgans CW
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells.
Volume: 106
Issue: 45
Pages: 19174-8
Protein
Organism: Mus musculus
Length: 95  
Fragment?: true
Publication  
First Author: Irie S
Year: 2014
Journal: Handb Exp Pharmacol
Title: TRPM1.
Volume: 222
Pages: 387-402
Publication
First Author: Xiong WH
Year: 2013
Journal: PLoS One
Title: Serum TRPM1 autoantibodies from melanoma associated retinopathy patients enter retinal on-bipolar cells and attenuate the electroretinogram in mice.
Volume: 8
Issue: 8
Pages: e69506
Publication
First Author: Shen Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: G-protein-mediated inhibition of the Trp channel TRPM1 requires the Gβγ dimer.
Volume: 109
Issue: 22
Pages: 8752-7
Publication
First Author: Ueno S
Year: 2013
Journal: PLoS One
Title: Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy.
Volume: 8
Issue: 11
Pages: e81507
Publication
First Author: Cao Y
Year: 2011
Journal: J Neurosci
Title: TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner.
Volume: 31
Issue: 32
Pages: 11521-6
Publication
First Author: Koike C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.
Volume: 107
Issue: 1
Pages: 332-7
Publication
First Author: Kozuka T
Year: 2017
Journal: J Neurosci
Title: The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit.
Volume: 37
Issue: 41
Pages: 9889-9900
Protein
Organism: Mus musculus
Length: 153  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1622  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1628  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1506  
Fragment?: false
Publication
First Author: Neuillé M
Year: 2015
Journal: Eur J Neurosci
Title: LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.
Volume: 42
Issue: 3
Pages: 1966-75
Publication
First Author: Pearring JN
Year: 2011
Journal: J Neurosci
Title: A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites.
Volume: 31
Issue: 27
Pages: 10060-6
Publication
First Author: Hori T
Year: 2021
Journal: Mol Brain
Title: Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior.
Volume: 14
Issue: 1
Pages: 61
Publication
First Author: Gerka-Stuyt J
Year: 2013
Journal: PLoS One
Title: Transient receptor potential melastatin 1: a hair cell transduction channel candidate.
Volume: 8
Issue: 10
Pages: e77213
Publication
First Author: Shen Y
Year: 2009
Journal: J Neurosci
Title: A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.
Volume: 29
Issue: 19
Pages: 6088-93
Publication
First Author: Wakeham CM
Year: 2020
Journal: J Comp Neurol
Title: Expression and distribution of trophoblast glycoprotein in the mouse retina.
Volume: 528
Issue: 10
Pages: 1660-1671
Publication
First Author: Hughes S
Year: 2012
Journal: Eur J Neurosci
Title: Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception.
Volume: 35
Issue: 1
Pages: 34-43
Publication
First Author: Miller AJ
Year: 2004
Journal: Cancer Res
Title: Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma.
Volume: 64
Issue: 2
Pages: 509-16
Publication
First Author: Xiong WH
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: The Effect of PKCα on the Light Response of Rod Bipolar Cells in the Mouse Retina.
Volume: 56
Issue: 8
Pages: 4961-74
Publication
First Author: Ray TA
Year: 2014
Journal: J Neurosci
Title: GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.
Volume: 34
Issue: 18
Pages: 6334-43
Publication  
First Author: Hasan N
Year: 2020
Journal: eNeuro
Title: LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.
Volume: 7
Issue: 1
Publication
First Author: Staaf S
Year: 2010
Journal: Gene Expr Patterns
Title: Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.
Volume: 10
Issue: 1
Pages: 65-74
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Duncan LM
Year: 1998
Journal: Cancer Res
Title: Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis.
Volume: 58
Issue: 7
Pages: 1515-20
Publication
First Author: Fang D
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Expression and Up-regulation of alternatively spliced transcripts of melastatin, a melanoma metastasis-related gene, in human melanoma cells.
Volume: 279
Issue: 1
Pages: 53-61
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716826
Stage: TS26
Assay Id: MGI:6711225
Age: embryonic day 18.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6711225
Age: postnatal day 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6711225
Age: postnatal day 5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6711225
Age: postnatal day 12
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6711225
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1715520
Stage: TS20
Assay Id: MGI:4458102
Age: embryonic day 12.0
Image: 6
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1715522
Stage: TS22
Assay Id: MGI:4458102
Age: embryonic day 14.0
Image: 6
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1715526
Stage: TS26
Assay Id: MGI:4458102
Age: embryonic day 18.0
Image: 6
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666820
Stage: TS20
Assay Id: MGI:4457730
Age: embryonic day 12.0
Image: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:4457730
Age: embryonic day 14.0
Image: 1
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666826
Stage: TS26
Assay Id: MGI:4457730
Age: embryonic day 18.0
Image: 1
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Female
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:4457730
Age: postnatal day 0
Image: 1
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457730
Age: postnatal day 4
Image: 1
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457730
Age: postnatal day 12
Image: 1
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457730
Age: postnatal adult
Image: 1
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666820
Stage: TS20
Assay Id: MGI:4458102
Age: embryonic day 12.0
Image: 6
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:4458102
Age: embryonic day 14.0
Image: 6
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666826
Stage: TS26
Assay Id: MGI:4458102
Age: embryonic day 18.0
Image: 6
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:4458102
Age: postnatal day 0
Image: 6
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458102
Age: postnatal day 4
Image: 6
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458102
Age: postnatal day 12
Image: 6
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458102
Age: postnatal adult
Image: 6
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4822326
Age: embryonic day 17.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4822326
Age: embryonic day 18.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822326
Age: postnatal day 0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822326
Age: postnatal day 2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822326
Age: postnatal day 4
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822326
Age: postnatal day 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4821977
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822326
Age: postnatal day 8
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6711186
Assay Type: RT-PCR
Annotation Date: 2021-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Stage: TS28
Assay Id: MGI:6711219
Age: postnatal adult
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1679827
Stage: TS27
Assay Id: MGI:4458102
Age: postnatal day 0
Image: 6
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:4457688
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1679828
Stage: TS28
Assay Id: MGI:4458102
Age: postnatal day 4
Image: 6
Detected: false
Specimen Num: 10