|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 125 for Trpm6

<< First    < Previous  |  Next >    Last >>
0.153s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: The TRPM subfamily of TRP channels includes TRPM6, which is a bifunctional protein comprising a TRP cation channel segment ion channel fused to a kinase domain with homology to the family of atypical alpha kinases []. The TRPM6 channel kinase plays a central role in systemic Mg(2+) homeostasis, and loss-of-function mutations in the human TRPM6 gene give rise to hypomagnesemia with secondary hypocalcemia (HSH) []. TRPM6 may have a role in neural tube closure during development, since mice with TRPM6 gene defects show neural tube defects and embryonic mortality [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Walder RY
Year: 2009
Journal: Hum Mol Genet
Title: Mice defective in Trpm6 show embryonic mortality and neural tube defects.
Volume: 18
Issue: 22
Pages: 4367-75
Publication
First Author: Schlingmann KP
Year: 2007
Journal: Biochim Biophys Acta
Title: TRPM6 and TRPM7--Gatekeepers of human magnesium metabolism.
Volume: 1772
Issue: 8
Pages: 813-21
Publication
First Author: Cao G
Year: 2008
Journal: Curr Biol
Title: RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain.
Volume: 18
Issue: 3
Pages: 168-76
Publication    
First Author: Chubanov V
Year: 2016
Journal: Elife
Title: Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.
Volume: 5
Publication
First Author: Nair AV
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy.
Volume: 109
Issue: 28
Pages: 11324-9
Publication  
First Author: Chubanov V
Year: 2014
Journal: Handb Exp Pharmacol
Title: TRPM6.
Volume: 222
Pages: 503-20
Publication
First Author: Voets T
Year: 2004
Journal: J Biol Chem
Title: TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
Volume: 279
Issue: 1
Pages: 19-25
Publication
First Author: Cuffe JS
Year: 2015
Journal: PLoS One
Title: Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.
Volume: 10
Issue: 2
Pages: e0117978
Protein
Organism: Mus musculus
Length: 2028  
Fragment?: false
Protein
Organism: Mus musculus
Length: 2028  
Fragment?: false
Publication
First Author: Woudenberg-Vrenken TE
Year: 2011
Journal: Nephron Physiol
Title: Transient receptor potential melastatin 6 knockout mice are lethal whereas heterozygous deletion results in mild hypomagnesemia.
Volume: 117
Issue: 2
Pages: p11-9
Publication
First Author: Nie M
Year: 2018
Journal: J Biol Chem
Title: Uromodulin regulates renal magnesium homeostasis through the ion channel transient receptor potential melastatin 6 (TRPM6).
Volume: 293
Issue: 42
Pages: 16488-16502
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal adult
Image: 6
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal day 12
Image: 6
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal day 4
Image: 6
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:4458107
Age: postnatal day 0
Image: 6
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Stage: TS26
Assay Id: MGI:4458107
Age: embryonic day 18.0
Image: 6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:4458107
Age: embryonic day 14.0
Image: 6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Stage: TS20
Assay Id: MGI:4458107
Age: embryonic day 12.0
Image: 6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457755
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457755
Age: postnatal day 12
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:4457755
Age: postnatal day 4
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:4457755
Age: postnatal day 0
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Stage: TS26
Assay Id: MGI:4457755
Age: embryonic day 18.0
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:4457755
Age: embryonic day 14.0
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Stage: TS20
Assay Id: MGI:4457755
Age: embryonic day 12.0
Image: 1
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:4398820
Age: embryonic day 18.5
Specimen Num: 15
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:4398820
Age: embryonic day 17.5
Specimen Num: 14
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:4398820
Age: embryonic day 16.5
Specimen Num: 13
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4398820
Age: embryonic day 15.5
Specimen Num: 12
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:4398820
Age: embryonic day 14.5
Specimen Num: 11
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:4398820
Age: embryonic day 13.5
Specimen Num: 10
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:4398820
Age: embryonic day 12.5
Specimen Num: 9
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4398820
Age: embryonic day 11.5
Specimen Num: 8
GXD Expression      
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:4398820
Age: embryonic day 10.5
Detected: true
Specimen Num: 7
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:160399
Stage: TS09
Assay Id: MGI:4398820
Age: embryonic day 6.5
Specimen Num: 3
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:4398820
Age: embryonic day 5.5
Specimen Num: 2
GXD Expression      
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160396
Stage: TS06
Assay Id: MGI:4398820
Age: embryonic day 4.5
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4398820
Age: embryonic day 6.5
Specimen Num: 3
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4398820
Age: embryonic day 5.5
Specimen Num: 2
GXD Expression      
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4398820
Age: embryonic day 4.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4398824
Assay Type: RT-PCR
Annotation Date: 2009-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4398826
Age: embryonic day 18.5
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:4398824
Assay Type: RT-PCR
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4398826
Age: embryonic day 18.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4398824
Assay Type: RT-PCR
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4398826
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715526
Stage: TS26
Assay Id: MGI:4458107
Age: embryonic day 18.0
Image: 6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715522
Stage: TS22
Assay Id: MGI:4458107
Age: embryonic day 14.0
Image: 6
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715520
Stage: TS20
Assay Id: MGI:4458107
Age: embryonic day 12.0
Image: 6
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:160429
Stage: TS09
Assay Id: MGI:4398820
Age: embryonic day 6.5
Specimen Num: 3
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:160428
Stage: TS08
Assay Id: MGI:4398820
Age: embryonic day 5.5
Specimen Num: 2
GXD Expression      
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160426
Stage: TS06
Assay Id: MGI:4398820
Age: embryonic day 4.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822332
Age: postnatal day 8
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822332
Age: postnatal day 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822332
Age: postnatal day 4
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822332
Age: postnatal day 2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822332
Age: postnatal day 0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4822332
Age: embryonic day 18.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4821984
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4822332
Age: embryonic day 17.0
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1679828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal adult
Image: 6
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1679828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal day 12
Image: 6
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1679828
Stage: TS28
Assay Id: MGI:4458107
Age: postnatal day 4
Image: 6
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:4457693
Assay Type: RT-PCR
Annotation Date: 2010-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1679827
Stage: TS27
Assay Id: MGI:4458107
Age: postnatal day 0
Image: 6
Detected: true
Specimen Num: 8
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3604015
Stage: TS15
Assay Id: MGI:4398820
Age: embryonic day 9.5
Specimen Num: 6
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:4398820
Age: embryonic day 8.5
Specimen Num: 5
GXD Expression        
Probe: MGI:4398823
Assay Type: Northern blot
Annotation Date: 2009-12-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3604011
Stage: TS11
Assay Id: MGI:4398820
Age: embryonic day 7.5
Specimen Num: 4
Publication
First Author: Ryazanov AG
Year: 1999
Journal: Curr Biol
Title: Alpha-kinases: a new class of protein kinases with a novel catalytic domain.
Volume: 9
Issue: 2
Pages: R43-5
Publication
First Author: Staaf S
Year: 2010
Journal: Gene Expr Patterns
Title: Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.
Volume: 10
Issue: 1
Pages: 65-74
Publication  
First Author: Ramsey IS
Year: 2006
Journal: Annu Rev Physiol
Title: An introduction to TRP channels.
Volume: 68
Pages: 619-47
Publication
First Author: Asai Y
Year: 2010
Journal: J Assoc Res Otolaryngol
Title: A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.
Volume: 11
Issue: 1
Pages: 27-37
Publication
First Author: Lechner SG
Year: 2009
Journal: EMBO J
Title: Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.
Volume: 28
Issue: 10
Pages: 1479-91
Publication      
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database