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Search results 1 to 100 out of 965 for Trps1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: The TRPS1 gene encodes a multi zinc-finger nuclear regulator of chondrocyte proliferation and differentiation []. Mutations in the gene cause trichorhinophalangeal syndrome (TRPS), an autosomal dominant skeletal dysplasia []. The Trps1 protein also acts as regulator of histone deacetylation, interacting with two histone deacetylases, Hdac1 and Hdac4, thereby increasing their activity [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: true
Publication  
First Author: Dias C
Year: 2013
Journal: Case Rep Genet
Title: Trichorhinophalangeal Syndrome Type I: A Patient with Two Novel and Different Mutations in the TRPS1 Gene.
Volume: 2013
Pages: 748057
Publication
First Author: Kaiser FJ
Year: 2004
Journal: Eur J Hum Genet
Title: Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal.
Volume: 12
Issue: 2
Pages: 121-6
Publication
First Author: Wuelling M
Year: 2013
Journal: Cell Cycle
Title: The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis.
Volume: 12
Issue: 14
Pages: 2219-32
Protein
Organism: Mus musculus/domesticus
Length: 1281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 1281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 994  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1285  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1096  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1035  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
GXD Expression    
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Anterior (upper)
Specimen Label: 3f Trps1 Anterior (upper)
Specimen Num: 1
GXD Expression    
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Middle (upper)
Specimen Label: 3f Trps1 Middle (upper)
Specimen Num: 3
GXD Expression    
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Middle (lower)
Specimen Label: 3f Trps1 Middle (lower)
Specimen Num: 4
GXD Expression    
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Posterior (lower)
Specimen Label: 3f Trps1 Posterior (lower)
Specimen Num: 6
GXD Expression    
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Anterior (lower)
Specimen Label: 3f Trps1 Anterior (lower)
Specimen Num: 2
GXD Expression
Probe: MGI:7581912
Assay Type: RNA in situ
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7581961
Age: embryonic day 14.5
Image: 3f Trps1 Posterior (upper)
Note: Expression medially in anterior half of posterior region of secondary palate.
Specimen Label: 3f Trps1 Posterior (upper)
Detected: true
Specimen Num: 5
Publication
First Author: Kaiser FJ
Year: 2003
Journal: J Biol Chem
Title: The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.
Volume: 278
Issue: 40
Pages: 38780-5
Protein
Organism: Mus musculus/domesticus
Length: 1240  
Fragment?: false
Publication  
First Author: Kunath M
Year: 2002
Journal: Mech Dev
Title: Expression of Trps1 during mouse embryonic development.
Volume: 119 Suppl 1
Pages: S117-20
Publication  
First Author: Socorro M
Year: 2020
Journal: Bone
Title: Trps1 transcription factor represses phosphate-induced expression of SerpinB2 in osteogenic cells.
Volume: 141
Pages: 115673
Publication
First Author: Suemoto H
Year: 2007
Journal: Dev Biol
Title: Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling.
Volume: 312
Issue: 2
Pages: 572-81
Publication
First Author: Kuzynski M
Year: 2014
Journal: J Biol Chem
Title: Dual role of the Trps1 transcription factor in dentin mineralization.
Volume: 289
Issue: 40
Pages: 27481-93
Publication
First Author: Gai Z
Year: 2010
Journal: J Am Soc Nephrol
Title: Trps1 haploinsufficiency promotes renal fibrosis by increasing Arkadia expression.
Volume: 21
Issue: 9
Pages: 1468-76
Publication
First Author: Nomir AG
Year: 2016
Journal: Genesis
Title: Fate mapping of Trps1 daughter cells during cardiac development using novel Trps1-Cre mice.
Volume: 54
Issue: 7
Pages: 379-88
Publication
First Author: Fantauzzo KA
Year: 2008
Journal: Hum Mol Genet
Title: A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice.
Volume: 17
Issue: 22
Pages: 3539-51
Publication
First Author: Gai Z
Year: 2009
Journal: J Am Soc Nephrol
Title: Trps1 functions downstream of Bmp7 in kidney development.
Volume: 20
Issue: 11
Pages: 2403-11
Publication
First Author: Michikami I
Year: 2012
Journal: Cell Tissue Res
Title: Trps1 is necessary for normal temporomandibular joint development.
Volume: 348
Issue: 1
Pages: 131-40
Publication
First Author: Fantauzzo KA
Year: 2008
Journal: Gene Expr Patterns
Title: Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling.
Volume: 8
Issue: 2
Pages: 51-7
Publication
First Author: Malik TH
Year: 2001
Journal: EMBO J
Title: Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.
Volume: 20
Issue: 7
Pages: 1715-25
Publication
First Author: Piscopo DM
Year: 2009
Journal: J Biol Chem
Title: Identification of the GATA factor TRPS1 as a repressor of the osteocalcin promoter.
Volume: 284
Issue: 46
Pages: 31690-703
Publication
First Author: Cornelissen LM
Year: 2020
Journal: Genes Dev
Title: TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development.
Volume: 34
Issue: 3-4
Pages: 179-193
Publication
First Author: Ackert-Bicknell CL
Year: 2012
Journal: Bone
Title: Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.
Volume: 50
Issue: 5
Pages: 1188-95
Publication
First Author: Wuelling M
Year: 2020
Journal: Dev Biol
Title: Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy.
Volume: 457
Issue: 1
Pages: 104-118
Publication
First Author: Sun Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression.
Volume: 456
Issue: 3
Pages: 721-6
Publication
First Author: Gui T
Year: 2013
Journal: Dev Biol
Title: The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.
Volume: 377
Issue: 2
Pages: 415-27
Publication
First Author: Fantauzzo KA
Year: 2012
Journal: Development
Title: Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis.
Volume: 139
Issue: 1
Pages: 203-14
Publication  
First Author: Cho KY
Year: 2019
Journal: Front Physiol
Title: Trps1 Regulates Development of Craniofacial Skeleton and Is Required for the Initiation of Palatal Shelves Fusion.
Volume: 10
Pages: 513
Publication
First Author: Nishioka K
Year: 2008
Journal: Bone
Title: Trps1 deficiency enlarges the proliferative zone of growth plate cartilage by upregulation of Pthrp.
Volume: 43
Issue: 1
Pages: 64-71
Publication
First Author: Goss M
Year: 2019
Journal: Mol Genet Metab
Title: Trps1 transcription factor regulates mineralization of dental tissues and proliferation of tooth organ cells.
Volume: 126
Issue: 4
Pages: 504-512
Publication
First Author: Fantauzzo KA
Year: 2012
Journal: PLoS Genet
Title: Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis.
Volume: 8
Issue: 11
Pages: e1003002
Publication
First Author: Itoh S
Year: 2008
Journal: Genes Cells
Title: Trps1 plays a pivotal role downstream of Gdf5 signaling in promoting chondrogenesis and apoptosis of ATDC5 cells.
Volume: 13
Issue: 4
Pages: 355-63
Publication
First Author: Kaiser FJ
Year: 2003
Journal: Hum Mol Genet
Title: Nuclear interaction of the dynein light chain LC8a with the TRPS1 transcription factor suppresses the transcriptional repression activity of TRPS1.
Volume: 12
Issue: 11
Pages: 1349-58
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191513
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Trps1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191513
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Trps1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191513
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Trps1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191513
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Trps1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191513
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Trps1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191513
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Trps1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6185907
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191513
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Trps1
Detected: true
Specimen Num: 7
Publication
First Author: Malik TH
Year: 2002
Journal: Mol Cell Biol
Title: Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes.
Volume: 22
Issue: 24
Pages: 8592-600
Publication
First Author: Wang L
Year: 2014
Journal: PLoS One
Title: Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.
Volume: 9
Issue: 1
Pages: e84485
Publication
First Author: Ishimori N
Year: 2008
Journal: J Bone Miner Res
Title: Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene.
Volume: 23
Issue: 9
Pages: 1529-37
Publication
First Author: Wuelling M
Year: 2009
Journal: Dev Biol
Title: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.
Volume: 328
Issue: 1
Pages: 40-53
Publication
First Author: Napierala D
Year: 2012
Journal: J Bone Miner Res
Title: Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice.
Volume: 27
Issue: 8
Pages: 1735-45
Publication  
First Author: Katayama K
Year: 2009
Journal: BMC Genet
Title: Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalities.
Volume: 10
Pages: 60
Publication
First Author: Mobley CG
Year: 2015
Journal: J Dent Res
Title: Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation.
Volume: 94
Issue: 8
Pages: 1128-34
Publication
First Author: Perdomo J
Year: 2002
Journal: Eur J Biochem
Title: The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.
Volume: 269
Issue: 23
Pages: 5885-92
Publication
First Author: Napierala D
Year: 2008
Journal: Hum Mol Genet
Title: Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.
Volume: 17
Issue: 14
Pages: 2244-54
UniProt Feature
Begin: 1
Description: Zinc finger transcription factor Trps1
Type: chain
End: 1281
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3816178
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816982
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3816178
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816982
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816178
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816982
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3816178
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816982
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: false
Specimen Num: 4