|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 689 for Tsc1

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
7248 | TSC1
Type: gene
Organism: human
•
•
•
•
•
Gene
464818 | TSC1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
533440 | TSC1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
417166 | TSC1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
714645 | TSC1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
100380126 | tsc1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
60445 | Tsc1
Type: gene
Organism: rat
•
•
•
•
•
Gene
480688 | TSC1
Type: gene
Organism: dog, domestic
•
•
•
•
•
HT Sample
TSC1
         
Organism Name: mouse, laboratory
Curation Status: Not curated (Transgenic sample)
•
•
•
•
•
Protein Coding Gene
MGI:1929183 | Tsc1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7439945
Assay Type: Western blot
Annotation Date: 2023-03-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7439948
Age: embryonic day 16.5
Image: 5
Specimen Label: Tsc1 cKO
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7439945
Assay Type: Western blot
Annotation Date: 2023-03-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7439948
Age: embryonic day 16.5
Image: 5
Specimen Label: Tsc1 cKO
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7439945
Assay Type: Western blot
Annotation Date: 2023-03-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7439948
Age: embryonic day 16.5
Image: 5
Specimen Label: Tsc1 cKO
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7439945
Assay Type: Western blot
Annotation Date: 2023-03-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7439948
Age: embryonic day 16.5
Image: 5
Specimen Label: Tsc1 cKO
Specimen Num: 9
•
•
•
•
•
Publication
23696872 | J:221022
First Author: Prabhakar S
Year: 2013
Journal: PLoS One
Title: Stochastic model of Tsc1 lesions in mouse brain.
Volume: 8
Issue: 5
Pages: e64224
•
•
•
•
•
Publication
29522719 | J:271435
First Author: Chen S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Tsc1 controls the development and function of alveolar macrophages.
Volume: 498
Issue: 3
Pages: 592-596
•
•
•
•
•
Publication
25175012 | J:274167
 
First Author: Zhu L
Year: 2014
Journal: Nat Commun
Title: TSC1 controls macrophage polarization to prevent inflammatory disease.
Volume: 5
Pages: 4696
•
•
•
•
•
Publication
17355907 | J:123206
First Author: Yasui S
Year: 2007
Journal: Mol Cell Neurosci
Title: The TSC1 gene product hamartin interacts with NADE.
Volume: 35
Issue: 1
Pages: 100-8
•
•
•
•
•
Publication
26159807 | J:238381
First Author: Fang C
Year: 2015
Journal: Cell Physiol Biochem
Title: Tsc1 is a Critical Regulator of Macrophage Survival and Function.
Volume: 36
Issue: 4
Pages: 1406-18
•
•
•
•
•
Publication
26296742 | J:291268
First Author: Wu H
Year: 2016
Journal: J Am Soc Nephrol
Title: Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney Growth.
Volume: 27
Issue: 4
Pages: 1145-58
•
•
•
•
•
Publication
31088250 | J:289730
First Author: Liu W
Year: 2019
Journal: Open Biol
Title: Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice.
Volume: 9
Issue: 5
Pages: 180262
•
•
•
•
•
Publication
24270422 | J:207832
First Author: Park Y
Year: 2013
Journal: J Clin Invest
Title: TSC1 regulates the balance between effector and regulatory T cells.
Volume: 123
Issue: 12
Pages: 5165-78
•
•
•
•
•
Publication
22891340 | J:188573
First Author: Xie DL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Tumor suppressor TSC1 is critical for T-cell anergy.
Volume: 109
Issue: 35
Pages: 14152-7
•
•
•
•
•
Publication
27593484 | J:333623
First Author: Yang T
Year: 2016
Journal: Cell Mol Immunol
Title: TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.
Volume: 13
Issue: 5
Pages: 640-50
•
•
•
•
•
Publication
12205640 | J:82532
First Author: Uhlmann EJ
Year: 2002
Journal: Ann Neurol
Title: Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures.
Volume: 52
Issue: 3
Pages: 285-96
•
•
•
•
•
Publication
22021912 | J:199987
First Author: Fu C
Year: 2012
Journal: Cereb Cortex
Title: GABAergic interneuron development and function is modulated by the Tsc1 gene.
Volume: 22
Issue: 9
Pages: 2111-9
•
•
•
•
•
Publication
22763451 | J:186699
First Author: Tsai PT
Year: 2012
Journal: Nature
Title: Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Volume: 488
Issue: 7413
Pages: 647-51
•
•
•
•
•
Publication
26000908 | J:235410
First Author: Ci X
Year: 2015
Journal: PLoS One
Title: TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation.
Volume: 10
Issue: 5
Pages: e0127527
•
•
•
•
•
Publication
31676823 | J:281566
First Author: Malik R
Year: 2019
Journal: Nat Commun
Title: Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons.
Volume: 10
Issue: 1
Pages: 4994
•
•
•
•
•
Publication
30696882 | J:275477
First Author: Wu Z
Year: 2019
Journal: Sci Rep
Title: Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse.
Volume: 9
Issue: 1
Pages: 837
•
•
•
•
•
Publication
25425965 | J:298256
First Author: Ding L
Year: 2014
Journal: Neoplasia
Title: Neurogenin 3-directed cre deletion of Tsc1 gene causes pancreatic acinar carcinoma.
Volume: 16
Issue: 11
Pages: 909-17
•
•
•
•
•
Publication
23664552 | J:201553
First Author: Normand EA
Year: 2013
Journal: Neuron
Title: Temporal and mosaic Tsc1 deletion in the developing thalamus disrupts thalamocortical circuitry, neural function, and behavior.
Volume: 78
Issue: 5
Pages: 895-909
•
•
•
•
•
Publication
22068588 | J:179742
First Author: Feliciano DM
Year: 2012
Journal: Hum Mol Genet
Title: Postnatal neurogenesis generates heterotopias, olfactory micronodules and cortical infiltration following single-cell Tsc1 deletion.
Volume: 21
Issue: 4
Pages: 799-810
•
•
•
•
•
Publication
27425891 | J:240823
 
First Author: Robens BK
Year: 2016
Journal: Neurobiol Dis
Title: Minute amounts of hamartin wildtype rescue the emergence of tuber-like lesions in conditional Tsc1 ablated mice.
Volume: 95
Pages: 134-44
•
•
•
•
•
Publication
21403402 | J:172004
First Author: Feliciano DM
Year: 2011
Journal: J Clin Invest
Title: Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice.
Volume: 121
Issue: 4
Pages: 1596-607
•
•
•
•
•
Publication
25639352 | J:232674
First Author: Fang F
Year: 2015
Journal: J Bone Miner Res
Title: Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion.
Volume: 30
Issue: 7
Pages: 1195-205
•
•
•
•
•
Publication
33957945 | J:329598
First Author: Deng Y
Year: 2021
Journal: J Neuroinflammation
Title: Conditional knockout of Tsc1 in RORγt-expressing cells induces brain damage and early death in mice.
Volume: 18
Issue: 1
Pages: 107
•
•
•
•
•
Publication
29127155 | J:259136
First Author: Woodford MR
Year: 2017
Journal: EMBO J
Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Volume: 36
Issue: 24
Pages: 3650-3665
•
•
•
•
•
Publication
34380034 | J:316945
First Author: Benthall KN
Year: 2021
Journal: Cell Rep
Title: Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning.
Volume: 36
Issue: 6
Pages: 109511
•
•
•
•
•
Publication
21765414 | J:176473
First Author: Yang K
Year: 2011
Journal: Nat Immunol
Title: The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.
Volume: 12
Issue: 9
Pages: 888-97
•
•
•
•
•
Publication
29358671 | J:303477
First Author: Xu S
Year: 2018
Journal: Cell Death Differ
Title: TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42.
Volume: 25
Issue: 9
Pages: 1549-1566
•
•
•
•
•
Publication
28079897 | J:277484
First Author: Luo Y
Year: 2017
Journal: Cell Death Dis
Title: Tsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response.
Volume: 8
Issue: 1
Pages: e2553
•
•
•
•
•
Publication
21828270 | J:174417
First Author: Zhou J
Year: 2011
Journal: Genes Dev
Title: Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.
Volume: 25
Issue: 15
Pages: 1595-600
•
•
•
•
•
Publication
34259631 | J:308504
   
First Author: Dalal JS
Year: 2021
Journal: Elife
Title: Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts.
Volume: 10
•
•
•
•
•
Publication
34135323 | J:337399
First Author: Amegandjin CA
Year: 2021
Journal: Nat Commun
Title: Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
Volume: 12
Issue: 1
Pages: 3653
•
•
•
•
•
Publication
23749404 | J:203971
First Author: Mietzsch U
Year: 2013
Journal: J Comp Neurol
Title: Comparative analysis of Tsc1 and Tsc2 single and double radial glial cell mutants.
Volume: 521
Issue: 16
Pages: 3817-31
•
•
•
•
•
Publication
25548102 | J:219817
First Author: Leech JD
Year: 2015
Journal: Mol Cancer Res
Title: A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas.
Volume: 13
Issue: 3
Pages: 548-55
•
•
•
•
•
Publication
15601645 | J:96138
First Author: Meikle L
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.
Volume: 14
Issue: 3
Pages: 429-35
•
•
•
•
•
Publication
16286931 | J:103933
First Author: Tavazoie SF
Year: 2005
Journal: Nat Neurosci
Title: Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.
Volume: 8
Issue: 12
Pages: 1727-34
•
•
•
•
•
Publication
10806479 | J:124755
First Author: Lamb RF
Year: 2000
Journal: Nat Cell Biol
Title: The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.
Volume: 2
Issue: 5
Pages: 281-7
•
•
•
•
•
Publication
26795955 | J:250192
 
First Author: Qin Z
Year: 2016
Journal: Sci Rep
Title: Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
Volume: 6
Pages: 19587
•
•
•
•
•
Publication
25271321 | J:216437
First Author: Shrestha S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.
Volume: 111
Issue: 41
Pages: 14858-63
•
•
•
•
•
Publication
23335988 | J:195705
First Author: Huang L
Year: 2013
Journal: PLoS One
Title: Specific disruption of Tsc1 in ovarian granulosa cells promotes ovulation and causes progressive accumulation of corpora lutea.
Volume: 8
Issue: 1
Pages: e54052
•
•
•
•
•
Publication
32309432 | J:301191
 
First Author: Yang C
Year: 2020
Journal: Biomed Res Int
Title: Mesenchymal Stem Cell-Specific and Preosteoblast-Specific Ablation of TSC1 in Mice Lead to Severe and Slight Spinal Dysplasia, Respectively.
Volume: 2020
Pages: 4572687
•
•
•
•
•
Publication
24633152 | J:215111
First Author: Pilipow K
Year: 2014
Journal: PLoS One
Title: Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals.
Volume: 9
Issue: 3
Pages: e91952
•
•
•
•
•
Publication
24614103 | J:209612
First Author: Wu J
Year: 2014
Journal: J Clin Invest
Title: iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
Volume: 124
Issue: 4
Pages: 1685-98
•
•
•
•
•
Publication
11875047 | J:75243
First Author: Kwiatkowski DJ
Year: 2002
Journal: Hum Mol Genet
Title: A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells.
Volume: 11
Issue: 5
Pages: 525-34
•
•
•
•
•
Publication
24129405 | J:208733
First Author: Ma A
Year: 2014
Journal: Hum Mol Genet
Title: Tsc1 deficiency-mediated mTOR hyperactivation in vascular endothelial cells causes angiogenesis defects and embryonic lethality.
Volume: 23
Issue: 3
Pages: 693-705
•
•
•
•
•
Publication
21212099 | J:169239
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
•
•
•
•
•
Publication
16912167 | J:112107
First Author: Wilson C
Year: 2006
Journal: Cancer Res
Title: Tsc1 haploinsufficiency without mammalian target of rapamycin activation is sufficient for renal cyst formation in Tsc1+/- mice.
Volume: 66
Issue: 16
Pages: 7934-8
•
•
•
•
•
Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
•
•
•
•
•
Publication
22025691 | J:180260
First Author: Goto J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Volume: 108
Issue: 45
Pages: E1070-9
•
•
•
•
•
Publication
30733194 | J:274206
First Author: Wu L
Year: 2019
Journal: Cancer Res
Title: Loss of FOXP3 and TSC1 Accelerates Prostate Cancer Progression through Synergistic Transcriptional and Posttranslational Regulation of c-MYC.
Volume: 79
Issue: 7
Pages: 1413-1425
•
•
•
•
•
Publication
21062901 | J:167241
First Author: Zeng LH
Year: 2011
Journal: Hum Mol Genet
Title: Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.
Volume: 20
Issue: 3
Pages: 445-54
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191516
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tsc1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191516
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tsc1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191516
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tsc1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191516
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tsc1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191516
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tsc1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191516
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tsc1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6185918
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191516
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tsc1
Detected: true
Specimen Num: 6
•
•
•
•
•
Publication
17522300 | J:121858
First Author: Meikle L
Year: 2007
Journal: J Neurosci
Title: A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
Volume: 27
Issue: 21
Pages: 5546-58
•
•
•
•
•
Publication
34732708 | J:337363
First Author: Jarmas AE
Year: 2021
Journal: Nat Commun
Title: Progenitor translatome changes coordinated by Tsc1 increase perception of Wnt signals to end nephrogenesis.
Volume: 12
Issue: 1
Pages: 6332
•
•
•
•
•
Publication
20616807 | J:186339
First Author: Kang YJ
Year: 2011
Journal: Cell Death Differ
Title: The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
Volume: 18
Issue: 1
Pages: 133-44
•
•
•
•
•
Publication
23475984 | J:211231
First Author: Daikoku T
Year: 2013
Journal: Mol Hum Reprod
Title: Conditional deletion of Tsc1 in the female reproductive tract impedes normal oviductal and uterine function by enhancing mTORC1 signaling in mice.
Volume: 19
Issue: 7
Pages: 463-72
•
•
•
•
•
Publication
29897930 | J:262829
First Author: Centini R
Year: 2018
Journal: PLoS One
Title: Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
Volume: 13
Issue: 6
Pages: e0197973
•
•
•
•
•
Publication
11438694 | J:70463
First Author: Kobayashi T
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.
Volume: 98
Issue: 15
Pages: 8762-7
•
•
•
•
•
Publication
24574959 | J:242056
 
First Author: Weston MC
Year: 2014
Journal: Front Mol Neurosci
Title: Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures.
Volume: 7
Pages: 1
•
•
•
•
•
Publication
34964695 | J:339463
First Author: Cho CS
Year: 2022
Journal: Autophagy
Title: Simultaneous loss of TSC1 and DEPDC5 in skeletal and cardiac muscles produces early-onset myopathy and cardiac dysfunction associated with oxidative damage and SQSTM1/p62 accumulation.
Volume: 18
Issue: 10
Pages: 2303-2322
•
•
•
•
•
Publication
32375878 | J:317669
First Author: Haji N
Year: 2020
Journal: Mol Autism
Title: Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Volume: 11
Issue: 1
Pages: 29
•
•
•
•
•
Publication
32927859 | J:306401
 
First Author: Guijarro MV
Year: 2020
Journal: Cells
Title: Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells.
Volume: 9
Issue: 9
•
•
•
•
•
Publication
36547785 | J:340850
First Author: Ghassib I
Year: 2023
Journal: Transgenic Res
Title: Off-target activity of the 8 kb Dmp1-Cre results in the deletion of Tsc1 gene in mouse intestinal mesenchyme.
Volume: 32
Issue: 1-2
Pages: 135-141
•
•
•
•
•
Publication
33071758 | J:313985
 
First Author: Wundrach D
Year: 2020
Journal: Front Mol Neurosci
Title: A Human TSC1 Variant Screening Platform in Gabaergic Cortical Interneurons for Genotype to Phenotype Assessments.
Volume: 13
Pages: 573409
•
•
•
•
•
Publication
35645731 | J:325114
 
First Author: Serra I
Year: 2022
Journal: Front Mol Neurosci
Title: Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.
Volume: 15
Pages: 831687
•
•
•
•
•
Publication
34777691 | J:321388
 
First Author: Rao YQ
Year: 2021
Journal: Oxid Med Cell Longev
Title: mTORC1 Activation in Chx10-Specific Tsc1 Knockout Mice Accelerates Retina Aging and Degeneration.
Volume: 2021
Pages: 6715758
•
•
•
•
•
Publication
28250050 | J:239666
First Author: Hägglund AC
Year: 2017
Journal: Dis Model Mech
Title: A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development.
Volume: 10
Issue: 3
Pages: 245-257
•
•
•
•
•
Publication
15851742 | J:101140
First Author: Ess KC
Year: 2005
Journal: Neurology
Title: Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex.
Volume: 64
Issue: 8
Pages: 1446-9
•
•
•
•
•
Publication
30305629 | J:268518
First Author: He R
Year: 2018
Journal: Nat Commun
Title: Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery.
Volume: 9
Issue: 1
Pages: 4183
•
•
•
•
•
Publication
36082078 | J:333492
 
First Author: Liang Y
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Lower ghrelin levels does not impact the metabolic benefit induced by Roux-en-Y gastric bypass.
Volume: 13
Pages: 891379
•
•
•
•
•
Publication
23049940 | J:192111
First Author: Gui YS
Year: 2012
Journal: PLoS One
Title: SPC-Cre-ERT2 transgenic mouse for temporal gene deletion in alveolar epithelial cells.
Volume: 7
Issue: 9
Pages: e46076
•
•
•
•
•
Publication
22362037 | J:183777
First Author: Shin J
Year: 2012
Journal: Blood
Title: Regulation of mast cell survival and function by tuberous sclerosis complex 1.
Volume: 119
Issue: 14
Pages: 3306-14
•
•
•
•
•
Publication
27039827 | J:236822
 
First Author: Yan B
Year: 2016
Journal: Nat Commun
Title: mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
Volume: 7
Pages: 11151
•
•
•
•
•
Publication
30067967 | J:270817
First Author: Drusian L
Year: 2018
Journal: Cell Rep
Title: mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma.
Volume: 24
Issue: 5
Pages: 1093-1104.e6
•
•
•
•
•
Publication
17714952 | J:134889
First Author: Zeng LH
Year: 2007
Journal: Neurobiol Dis
Title: Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex.
Volume: 28
Issue: 2
Pages: 184-96
•
•
•
•
•
Publication
23664616 | J:197979
First Author: Bateup HS
Year: 2013
Journal: Neuron
Title: Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis.
Volume: 78
Issue: 3
Pages: 510-22
•
•
•
•
•
Publication
31506280 | J:282628
First Author: Zarei M
Year: 2019
Journal: J Exp Med
Title: Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.
Volume: 216
Issue: 11
Pages: 2635-2652
•
•
•
•
•
Publication
21709159 | J:179182
First Author: Wu Q
Year: 2011
Journal: J Immunol
Title: The tuberous sclerosis complex-mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells.
Volume: 187
Issue: 3
Pages: 1106-12
•
•
•
•
•
Publication
29294307 | J:262105
First Author: Luo Y
Year: 2018
Journal: Exp Cell Res
Title: Tsc1-dependent transcriptional programming of dendritic cell homeostasis and function.
Volume: 363
Issue: 1
Pages: 73-83
•
•
•
•
•
Publication
31780742 | J:283832
First Author: Kosillo P
Year: 2019
Journal: Nat Commun
Title: Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility.
Volume: 10
Issue: 1
Pages: 5426
•
•
•
•
•
Publication
29898392 | J:270677
First Author: Benthall KN
Year: 2018
Journal: Cell Rep
Title: Corticostriatal Transmission Is Selectively Enhanced in Striatonigral Neurons with Postnatal Loss of Tsc1.
Volume: 23
Issue: 11
Pages: 3197-3208
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom