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Search results 1 to 100 out of 260 for Tshr

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
7253 | TSHR
Type: gene
Organism: human
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Gene
453077 | TSHR
Type: gene
Organism: chimpanzee
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Gene
281553 | TSHR
Type: gene
Organism: cattle
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Gene
428900 | TSHR
Type: gene
Organism: chicken
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Gene
560609 | tshr
Type: gene
Organism: zebrafish
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Gene
574251 | TSHR
Type: gene
Organism: macaque, rhesus
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Gene
100492843 | tshr
Type: gene
Organism: frog, western clawed
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Gene
key_36204 | TSHR
Type: gene
Organism: pig, domestic
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Gene
25360 | Tshr
Type: gene
Organism: rat
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Gene
403968 | TSHR
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:98849 | Tshr
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
     
Probe: MGI:3793953
Assay Type: RT-PCR
Annotation Date: 2008-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706826
Stage: TS26
Assay Id: MGI:3793957
Age: embryonic day 18.5
Specimen Label: TshR B6
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3793953
Assay Type: RT-PCR
Annotation Date: 2008-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706826
Stage: TS26
Assay Id: MGI:3793957
Age: embryonic day 18.5
Specimen Label: TshR DHTP/B6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3793953
Assay Type: RT-PCR
Annotation Date: 2008-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706826
Stage: TS26
Assay Id: MGI:3793957
Age: embryonic day 18.5
Specimen Label: TshR B6/Sv-F1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:3793953
Assay Type: RT-PCR
Annotation Date: 2008-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706826
Stage: TS26
Assay Id: MGI:3793957
Age: embryonic day 18.5
Specimen Label: TshR DHTP/B6/Sv-F1
Detected: true
Specimen Num: 14
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Publication
29421660 | J:270324
First Author: Zhou L
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.
Volume: 497
Issue: 1
Pages: 39-45
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Publication
20152797 | J:329174
First Author: Elgadi A
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Tissue-specific knockout of TSHr in white adipose tissue increases adipocyte size and decreases TSH-induced lipolysis.
Volume: 393
Issue: 3
Pages: 526-30
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Publication
22334716 | J:183796
First Author: Nakahara M
Year: 2012
Journal: Endocrinology
Title: Adoptive transfer of antithyrotropin receptor (TSHR) autoimmunity from TSHR knockout mice to athymic nude mice.
Volume: 153
Issue: 4
Pages: 2034-42
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Publication
11833606 | J:329173
First Author: Sprenkle PM
Year: 2001
Journal: J Assoc Res Otolaryngol
Title: Consequences of hypothyroidism on auditory system function in Tshr mutant (hyt) mice.
Volume: 2
Issue: 4
Pages: 312-29
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Publication
11833607 | J:329182
First Author: Sprenkle PM
Year: 2001
Journal: J Assoc Res Otolaryngol
Title: Development of auditory brainstem responses (ABRs) in Tshr mutant mice derived from euthyroid and hypothyroid dams.
Volume: 2
Issue: 4
Pages: 330-47
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Publication
11833608 | J:263616
First Author: Sprenkle PM
Year: 2001
Journal: J Assoc Res Otolaryngol
Title: Prevention of auditory dysfunction in hypothyroid Tshr mutant mice by thyroxin treatment during development.
Volume: 2
Issue: 4
Pages: 348-61
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Publication
31184281 | J:296992
First Author: McLachlan SM
Year: 2019
Journal: Thyroid
Title: A Mouse Thyrotropin Receptor A-Subunit Transgene Expressed in Thyroiditis-Prone Mice May Provide Insight into Why Graves' Disease Only Occurs in Humans.
Volume: 29
Issue: 8
Pages: 1138-1146
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Publication
22996689 | J:192466
First Author: Baliram R
Year: 2012
Journal: J Clin Invest
Title: Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling.
Volume: 122
Issue: 10
Pages: 3737-41
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Publication
31179344 | J:289257
 
First Author: Yang Y
Year: 2019
Journal: J Diabetes Res
Title: The Adverse Effects of Thyrotropin Absence on Pancreatic β Cell Function in Mice.
Volume: 2019
Pages: 9536032
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Publication
7794253 | J:26080
First Author: Drvota V
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Evidence for the presence of functional thyrotropin receptor in cardiac muscle.
Volume: 211
Issue: 2
Pages: 426-31
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Publication
31998431 | J:291446
 
First Author: Wang X
Year: 2020
Journal: Oxid Med Cell Longev
Title: Thyroid Stimulating Hormone Triggers Hepatic Mitochondrial Stress through Cyclophilin D Acetylation.
Volume: 2020
Pages: 1249630
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Publication
14567913 | J:86156
First Author: Abe E
Year: 2003
Journal: Cell
Title: TSH is a negative regulator of skeletal remodeling.
Volume: 115
Issue: 2
Pages: 151-62
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Publication
8170469 | J:16854
First Author: Stein SA
Year: 1994
Journal: Mol Endocrinol
Title: Identification of a point mutation in the thyrotropin receptor of the hyt/hyt hypothyroid mouse.
Volume: 8
Issue: 2
Pages: 129-38
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Publication
12432094 | J:80513
First Author: Marians RC
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice.
Volume: 99
Issue: 24
Pages: 15776-81
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Publication
25016105 | J:328793
 
First Author: Mouri A
Year: 2014
Journal: Psychoneuroendocrinology
Title: Thyrotoropin receptor knockout changes monoaminergic neuronal system and produces methylphenidate-sensitive emotional and cognitive dysfunction.
Volume: 48
Pages: 147-61
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Publication
20555026 | J:329175
First Author: Nakahara M
Year: 2010
Journal: Endocrinology
Title: Enhanced response to mouse thyroid-stimulating hormone (TSH) receptor immunization in TSH receptor-knockout mice.
Volume: 151
Issue: 8
Pages: 4047-54
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Publication
23665701 | J:289778
First Author: Wang T
Year: 2013
Journal: Endocr J
Title: Decreased fasting blood glucose is associated with impaired hepatic glucose production in thyroid-stimulating hormone receptor knockout mice.
Volume: 60
Issue: 8
Pages: 941-50
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Publication
24065308 | J:329097
First Author: Huang W
Year: 2014
Journal: Endocrine
Title: Functional thyrotropin receptor expression in the ventricle and the effects on ventricular BNP secretion.
Volume: 46
Issue: 2
Pages: 328-39
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Publication
22916127 | J:190054
First Author: Endo T
Year: 2012
Journal: PLoS One
Title: Dominant negative effect of mutated thyroid stimulating hormone receptor (P556L) causes hypothyroidism in C.RF-Tshr(hyt/wild) mice.
Volume: 7
Issue: 8
Pages: e42358
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Publication
22496347 | J:187112
First Author: Endo T
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Expression of functional TSH receptor in white adipose tissues of hyt/hyt mice induces lipolysis in vivo.
Volume: 302
Issue: 12
Pages: E1569-75
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Publication
18559984 | J:139995
First Author: Endo T
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis.
Volume: 295
Issue: 2
Pages: E514-8
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Publication
23880310 | J:203889
First Author: Endo T
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Excess TSH causes abnormal skeletal development in young mice with hypothyroidism via suppressive effects on the growth plate.
Volume: 305
Issue: 5
Pages: E660-6
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Publication
2556796 | J:32290
First Author: Parmentier M
Year: 1989
Journal: Science
Title: Molecular cloning of the thyrotropin receptor.
Volume: 246
Issue: 4937
Pages: 1620-2
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Publication
10479389 | J:57620
First Author: Patibandla SA
Year: 1999
Journal: J Autoimmun
Title: Comparison of immune responses to extracellular domains of mouse and human thyrotropin receptor.
Volume: 13
Issue: 2
Pages: 205-13
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Publication
25559747 | J:337999
 
First Author: Ma S
Year: 2015
Journal: Sci Rep
Title: Thyrotropin and obesity: increased adipose triglyceride content through glycerol-3-phosphate acyltransferase 3.
Volume: 5
Pages: 7633
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Publication
19299442 | J:148712
First Author: Rivas M
Year: 2009
Journal: Mol Endocrinol
Title: The DREAM protein is associated with thyroid enlargement and nodular development.
Volume: 23
Issue: 6
Pages: 862-70
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Publication
27179782 | J:235763
First Author: Zhang T
Year: 2016
Journal: Biochem Biophys Res Commun
Title: TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
Volume: 476
Issue: 2
Pages: 75-81
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Publication
32812397 | J:329096
First Author: Lundbäck V
Year: 2020
Journal: Physiol Rep
Title: Adipose-specific inactivation of thyroid stimulating hormone receptors in mice modifies body weight, temperature and gene expression in adipocytes.
Volume: 8
Issue: 16
Pages: e14538
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Publication
11440271 | J:70498
First Author: Neumann S
Year: 2001
Journal: Horm Metab Res
Title: Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
Volume: 33
Issue: 5
Pages: 263-9
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Publication
11796491 | J:74980
First Author: Nguyen LQ
Year: 2002
Journal: Endocrinology
Title: Cloning of the cat TSH receptor and evidence against an autoimmune etiology of feline hyperthyroidism.
Volume: 143
Issue: 2
Pages: 395-402
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Publication
28212844 | J:248725
 
First Author: Li Y
Year: 2017
Journal: Mol Cell Endocrinol
Title: Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Volume: 446
Pages: 70-80
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Publication
14630711 | J:105588
First Author: Pichurin PN
Year: 2004
Journal: Endocrinology
Title: Thyrotropin receptor knockout mice: studies on immunological tolerance to a major thyroid autoantigen.
Volume: 145
Issue: 3
Pages: 1294-301
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Publication
26389690 | J:232751
First Author: Atkins SJ
Year: 2015
Journal: Endocrinology
Title: Disrupted TSH Receptor Expression in Female Mouse Lung Fibroblasts Alters Subcellular IGF-1 Receptor Distribution.
Volume: 156
Issue: 12
Pages: 4731-40
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Publication
11312274 | J:70138
First Author: Govaerts C
Year: 2001
Journal: J Biol Chem
Title: A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor.
Volume: 276
Issue: 25
Pages: 22991-9
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Publication
16908863 | J:112918
First Author: Hase H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: TNFalpha mediates the skeletal effects of thyroid-stimulating hormone.
Volume: 103
Issue: 34
Pages: 12849-54
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Publication
18218727 | J:134080
First Author: Yamoah K
Year: 2008
Journal: Mol Endocrinol
Title: High-mobility group box proteins modulate tumor necrosis factor-alpha expression in osteoclastogenesis via a novel deoxyribonucleic acid sequence.
Volume: 22
Issue: 5
Pages: 1141-53
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Publication
12907760 | J:86315
First Author: Moeller LC
Year: 2003
Journal: Mol Endocrinol
Title: Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.
Volume: 17
Issue: 11
Pages: 2295-302
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Publication
21220306 | J:168249
First Author: Franco AT
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
Volume: 108
Issue: 4
Pages: 1615-20
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Publication
19589858 | J:158141
First Author: Unfried C
Year: 2009
Journal: Endocrinology
Title: Impact of melatonin and molecular clockwork components on the expression of thyrotropin beta-chain (Tshb) and the Tsh receptor in the mouse pars tuberalis.
Volume: 150
Issue: 10
Pages: 4653-62
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Publication
9075728 | J:39893
First Author: Vlase H
Year: 1997
Journal: Endocrinology
Title: Folding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain.
Volume: 138
Issue: 4
Pages: 1658-66
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Publication
12432093 | J:80538
First Author: Postiglione MP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland.
Volume: 99
Issue: 24
Pages: 15462-7
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Protein Coding Gene
MGP_CAROLIEiJ_G0018002 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019288 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019900 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029760 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018847 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
28874841 | J:255541
First Author: Aghajanian P
Year: 2017
Journal: Sci Rep
Title: Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation.
Volume: 7
Issue: 1
Pages: 10432
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Publication
34276566 | J:320985
 
First Author: Latif R
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Long Term Rescue of the TSH Receptor Knock-Out Mouse - Thyroid Stem Cell Transplantation Restores Thyroid Function.
Volume: 12
Pages: 706101
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Publication
25933205 | J:235247
First Author: Liu S
Year: 2015
Journal: PLoS One
Title: AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.
Volume: 10
Issue: 5
Pages: e0124951
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Publication
- | J:221489
     
First Author: Reyna C
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for freckle
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Publication
- | J:213054
     
First Author: Dionne LA
Year: 2014
Journal: MGI Direct Data Submission
Title: The hypothyroid 2 Jackson mutation
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Publication
- | J:210510
     
First Author: Harris BS
Year: 2014
Journal: MGI Direct Data Submission
Title: A spontaneous mutation in thyroid stimulating hormone receptor that allows partial fertility in both females and males
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Publication
7209519 | J:6479
First Author: Beamer WJ
Year: 1981
Journal: Science
Title: Inherited primary hypothyroidism in mice.
Volume: 212
Issue: 4490
Pages: 61-3
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Publication
10575115 | J:110962
First Author: Li D
Year: 1999
Journal: Hear Res
Title: Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse.
Volume: 138
Issue: 1-2
Pages: 65-72
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Publication
11530227 | J:85902
First Author: Kincaid AE
Year: 2001
Journal: Neuroscience
Title: Spontaneous circling behavior and dopamine neuron loss in a genetically hypothyroid mouse.
Volume: 105
Issue: 4
Pages: 891-8
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Publication
7956935 | J:21594
First Author: Solé E
Year: 1994
Journal: Endocrinology
Title: Thyroid hormone controls the cell-specific expression of the kidney androgen-regulated protein gene in S3 mouse kidney cells.
Volume: 135
Issue: 5
Pages: 2120-9
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Publication
10570273 | J:111014
First Author: Foster MP
Year: 1999
Journal: J Immunol
Title: Proliferation of bone marrow pro-B cells is dependent on stimulation by the pituitary/thyroid axis.
Volume: 163
Issue: 11
Pages: 5883-90
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Publication
35098920 | J:322640
   
First Author: Gomez GA
Year: 2022
Journal: Elife
Title: Differences in pathways contributing to thyroid hormone effects on postnatal cartilage calcification versus secondary ossification center development.
Volume: 11
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Publication
16780814 | J:111112
First Author: Song L
Year: 2006
Journal: Brain Res
Title: Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshrhyt mutant mice.
Volume: 1101
Issue: 1
Pages: 59-72
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Publication
11690529 | J:72929
First Author: Jiang JY
Year: 2001
Journal: Reproduction
Title: Characteristics of infertility in female hypothyroid (hyt) mice.
Volume: 122
Issue: 5
Pages: 695-700
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Publication
8575993 | J:30383
First Author: O'Malley BW Jr
Year: 1995
Journal: Hear Res
Title: Hearing loss and cochlear abnormalities in the congenital hypothyroid (hyt/hyt) mouse.
Volume: 88
Issue: 1-2
Pages: 181-9
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Publication
7789342 | J:26725
First Author: Gu WX
Year: 1995
Journal: Endocrinology
Title: The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.
Volume: 136
Issue: 7
Pages: 3146-53
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Publication
9183515 | J:41267
First Author: Biesiada E
Year: 1996
Journal: Adv Neuroimmunol
Title: Biology of the congenitally hypothyroid hyt/hyt mouse.
Volume: 6
Issue: 4
Pages: 309-46
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Publication
2590150 | J:32748
First Author: Laffan EW
Year: 1989
Journal: Behav Neural Biol
Title: Development of rotorod performance in normal and congenitally hypothyroid mutant mice.
Volume: 52
Issue: 3
Pages: 411-6
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Publication
- | J:32749
 
First Author: Southard JL
Year: 1977
Journal: Mouse News Lett
Title: Petite (pet)
Volume: 56
Pages: 41
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Publication
8372095 | J:20026
First Author: Erf GF
Year: 1993
Journal: Proc Soc Exp Biol Med
Title: Immune development in young-adult C.RF-hyt mice is affected by congenital and maternal hypothyroidism.
Volume: 204
Issue: 1
Pages: 40-8
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Publication
10231871 | J:55839
First Author: Khan JY
Year: 1999
Journal: Pediatr Res
Title: Effect of primary congenital hypothyroidism upon expression of genes mediating murine brain glucose uptake.
Volume: 45
Issue: 5 Pt 1
Pages: 718-25
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Publication
7072984 | J:6748
First Author: Beamer WG
Year: 1982
Journal: Anat Rec
Title: Defective thyroid ontogenesis in fetal hypothyroid (hyt/hyt) mice.
Volume: 202
Issue: 3
Pages: 387-93
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Publication
- | J:13864
 
First Author: Beamer WG
Year: 1980
Journal: Mouse News Lett
Title: Petite (pet) to hypothyroid (hyt).
Volume: 63
Pages: 20
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Publication
8807634 | J:33604
First Author: Solé E
Year: 1996
Journal: Mol Cell Endocrinol
Title: Effects of thyroid hormone on the androgenic expression of KAP gene in mouse kidney.
Volume: 119
Issue: 2
Pages: 147-59
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Publication
2541503 | J:32289
First Author: Libert F
Year: 1989
Journal: Science
Title: Selective amplification and cloning of four new members of the G protein-coupled receptor family.
Volume: 244
Issue: 4904
Pages: 569-72
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