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Search results 1 to 100 out of 373 for Tslp

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1.071s

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
85480 | TSLP
Type: gene
Organism: human
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Gene
688621 | Tslp
Type: gene
Organism: rat
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Gene
607671 | TSLP
Type: gene
Organism: dog, domestic
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Gene
737202 | TSLP
Type: gene
Organism: chimpanzee
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Gene
617637 | TSLP
Type: gene
Organism: cattle
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Gene
706194 | TSLP
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1855696 | Tslp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029189 | TSLP
Type: Family
Description: Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells []. TSLP has proliferative effects on the myeloid cell line []and may initiate asthma or atopic dermatitis responses by directly activating mast cells [].
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Publication
11480573 | J:70816
First Author: Quentmeier H
Year: 2001
Journal: Leukemia
Title: Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation.
Volume: 15
Issue: 8
Pages: 1286-92
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Protein
Q9JIE6
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
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Publication
11418668 | -
First Author: Reche PA
Year: 2001
Journal: J Immunol
Title: Human thymic stromal lymphopoietin preferentially stimulates myeloid cells.
Volume: 167
Issue: 1
Pages: 336-43
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Publication
17242164 | -
First Author: Allakhverdi Z
Year: 2007
Journal: J Exp Med
Title: Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells.
Volume: 204
Issue: 2
Pages: 253-8
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Publication
19557146 | J:150647
First Author: Demehri S
Year: 2009
Journal: PLoS Biol
Title: Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma.
Volume: 7
Issue: 5
Pages: e1000067
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Publication
14512322 | J:87635
First Author: Osborn MJ
Year: 2004
Journal: Blood
Title: Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis.
Volume: 103
Issue: 3
Pages: 843-51
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Publication
32304753 | J:329422
First Author: Lai JF
Year: 2020
Journal: J Allergy Clin Immunol
Title: TSLP drives acute TH2-cell differentiation in lungs.
Volume: 146
Issue: 6
Pages: 1406-1418.e7
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Publication
21841801 | J:176058
First Author: Siracusa MC
Year: 2011
Journal: Nature
Title: TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.
Volume: 477
Issue: 7363
Pages: 229-33
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Publication
22585305 | J:187770
First Author: Zhang Y
Year: 2012
Journal: Eur J Immunol
Title: DC-derived TSLP promotes Th2 polarization in LPS-primed allergic airway inflammation.
Volume: 42
Issue: 7
Pages: 1735-43
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Publication
32600615 | J:305051
First Author: Ohno T
Year: 2020
Journal: Biochem Biophys Res Commun
Title: TSLP is a negative regulator of RANKL-induced osteoclastogenesis.
Volume: 530
Issue: 3
Pages: 508-512
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Publication
21484783 | J:177311
First Author: Kitajima M
Year: 2011
Journal: Eur J Immunol
Title: TSLP enhances the function of helper type 2 cells.
Volume: 41
Issue: 7
Pages: 1862-71
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Publication
16172260 | J:107431
First Author: Al-Shami A
Year: 2005
Journal: J Exp Med
Title: A role for TSLP in the development of inflammation in an asthma model.
Volume: 202
Issue: 6
Pages: 829-39
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Publication
24094650 | J:334117
First Author: Wilson SR
Year: 2013
Journal: Cell
Title: The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch.
Volume: 155
Issue: 2
Pages: 285-95
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Publication
17702899 | J:149105
First Author: Chappaz S
Year: 2007
Journal: Blood
Title: Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice.
Volume: 110
Issue: 12
Pages: 3862-70
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Publication
31723054 | J:297307
 
First Author: Li S
Year: 2019
Journal: JCI Insight
Title: TSLP protects against liver I/R injury via activation of the PI3K/Akt pathway.
Volume: 4
Issue: 22
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Publication
22832486 | J:196493
First Author: Leyva-Castillo JM
Year: 2013
Journal: J Invest Dermatol
Title: TSLP produced by keratinocytes promotes allergen sensitization through skin and thereby triggers atopic march in mice.
Volume: 133
Issue: 1
Pages: 154-63
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Publication
31480519 | J:280281
 
First Author: Han NR
Year: 2019
Journal: J Clin Med
Title: TSLP Exacerbates Septic Inflammation via Murine Double Minute 2 (MDM2) Signaling Pathway.
Volume: 8
Issue: 9
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Publication
31227217 | J:291701
First Author: Liu D
Year: 2019
Journal: Biochem Biophys Res Commun
Title: TSLP promote M2 macrophages polarization and cardiac healing after myocardial infarction.
Volume: 516
Issue: 2
Pages: 437-444
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Publication
37525585 | J:344370
First Author: Tanaka Y
Year: 2023
Journal: Eur J Immunol
Title: Skin-derived TSLP stimulates skin migratory dendritic cells to promote the expansion of regulatory T cells.
Volume: 53
Issue: 10
Pages: e2350390
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Publication
23437132 | J:197193
First Author: Jang S
Year: 2013
Journal: PLoS One
Title: TSLP promotes induction of Th2 differentiation but is not necessary during established allergen-induced pulmonary disease.
Volume: 8
Issue: 2
Pages: e56433
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Publication
19273626 | J:146749
First Author: Taylor BC
Year: 2009
Journal: J Exp Med
Title: TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.
Volume: 206
Issue: 3
Pages: 655-67
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Publication
36050303 | J:344134
First Author: Segaud J
Year: 2022
Journal: Nat Commun
Title: Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march.
Volume: 13
Issue: 1
Pages: 4703
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Publication
24751726 | J:214773
First Author: Han NR
Year: 2014
Journal: J Invest Dermatol
Title: TSLP induces mast cell development and aggravates allergic reactions through the activation of MDM2 and STAT6.
Volume: 134
Issue: 10
Pages: 2521-2530
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Publication
18711124 | J:138973
First Author: He R
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: TSLP acts on infiltrating effector T cells to drive allergic skin inflammation.
Volume: 105
Issue: 33
Pages: 11875-80
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Publication
38053996 | J:347966
 
First Author: Wang ZY
Year: 2023
Journal: Front Immunol
Title: Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.
Volume: 14
Pages: 1273182
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Publication
26573878 | J:247183
First Author: Elder MJ
Year: 2016
Journal: Eur J Immunol
Title: TSLP production by dendritic cells is modulated by IL-1β and components of the endoplasmic reticulum stress response.
Volume: 46
Issue: 2
Pages: 455-63
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Publication
34925342 | J:322032
 
First Author: Lee WJ
Year: 2021
Journal: Front Immunol
Title: Cutaneous Neuroimmune Interactions of TSLP and TRPV4 Play Pivotal Roles in Dry Skin-Induced Pruritus.
Volume: 12
Pages: 772941
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Publication
18566323 | J:138719
First Author: Jensen CT
Year: 2008
Journal: Blood
Title: FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis.
Volume: 112
Issue: 6
Pages: 2297-304
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Publication
23213237 | J:193098
First Author: Negishi H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction.
Volume: 109
Issue: 51
Pages: 21016-21
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Publication
36107619 | J:331385
 
First Author: Yao W
Year: 2022
Journal: JCI Insight
Title: Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment.
Volume: 7
Issue: 21
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Publication
28730605 | J:286861
First Author: Sugita J
Year: 2017
Journal: Immun Inflamm Dis
Title: Contributions of Interleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival inflammation model.
Volume: 5
Issue: 4
Pages: 515-525
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Publication
25172162 | J:319108
 
First Author: Kumar S
Year: 2014
Journal: Toxicology
Title: Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation.
Volume: 325
Pages: 42-51
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Publication
19155513 | J:144318
First Author: Headley MB
Year: 2009
Journal: J Immunol
Title: TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses.
Volume: 182
Issue: 3
Pages: 1641-7
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Publication
18461563 | J:136211
First Author: Miyata M
Year: 2008
Journal: Eur J Immunol
Title: Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis.
Volume: 38
Issue: 6
Pages: 1487-92
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Publication
23363980 | J:194548
First Author: Kim BS
Year: 2013
Journal: Sci Transl Med
Title: TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation.
Volume: 5
Issue: 170
Pages: 170ra16
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Publication
30575775 | J:268469
First Author: Hiraishi Y
Year: 2018
Journal: Sci Rep
Title: IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation.
Volume: 8
Issue: 1
Pages: 18052
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Publication
19666528 | J:151957
First Author: Massacand JC
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function.
Volume: 106
Issue: 33
Pages: 13968-73
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Publication
28115699 | J:240878
First Author: Ganti KP
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium.
Volume: 114
Issue: 6
Pages: E951-E960
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Publication
28701507 | J:251327
First Author: Han M
Year: 2017
Journal: J Immunol
Title: The Innate Cytokines IL-25, IL-33, and TSLP Cooperate in the Induction of Type 2 Innate Lymphoid Cell Expansion and Mucous Metaplasia in Rhinovirus-Infected Immature Mice.
Volume: 199
Issue: 4
Pages: 1308-1318
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Publication
23698100 | J:202873
First Author: Yockey LJ
Year: 2013
Journal: J Invest Dermatol
Title: The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation.
Volume: 133
Issue: 12
Pages: 2714-2721
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Publication
21490155 | J:173224
First Author: Olkhanud PB
Year: 2011
Journal: J Immunol
Title: Thymic stromal lymphopoietin is a key mediator of breast cancer progression.
Volume: 186
Issue: 10
Pages: 5656-62
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Publication
19017958 | J:142196
First Author: Rochman Y
Year: 2008
Journal: J Immunol
Title: The role of thymic stromal lymphopoietin in CD8+ T cell homeostasis.
Volume: 181
Issue: 11
Pages: 7699-705
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Publication
24723460 | J:328378
First Author: Proctor WR
Year: 2014
Journal: Hepatology
Title: Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice.
Volume: 60
Issue: 5
Pages: 1741-52
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Publication
37427591 | J:338858
 
First Author: Messerschmidt JL
Year: 2023
Journal: JCI Insight
Title: TSLP/dendritic cell axis promotes CD4+ T cell tolerance to the gut microbiome.
Volume: 8
Issue: 13
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Publication
15263024 | J:108209
First Author: Al-Shami A
Year: 2004
Journal: J Exp Med
Title: A role for thymic stromal lymphopoietin in CD4(+) T cell development.
Volume: 200
Issue: 2
Pages: 159-68
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Publication
21820333 | J:175844
First Author: Reardon C
Year: 2011
Journal: Immunity
Title: Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation.
Volume: 35
Issue: 2
Pages: 223-35
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GO Term
GO:0071925 | thymic stromal lymphopoietin production
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Publication
22354320 | J:199558
First Author: Han H
Year: 2012
Journal: Mucosal Immunol
Title: Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma.
Volume: 5
Issue: 3
Pages: 342-51
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Publication
29339496 | J:257761
First Author: Ochiai S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells.
Volume: 115
Issue: 5
Pages: 1033-1038
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Publication
18664628 | J:140217
First Author: Mazzucchelli R
Year: 2008
Journal: Blood
Title: Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
Volume: 112
Issue: 8
Pages: 3283-92
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Publication
22281511 | J:182756
First Author: Iseki M
Year: 2012
Journal: Int Immunol
Title: Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4.
Volume: 24
Issue: 3
Pages: 183-95
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Publication
25365222 | J:219531
First Author: Han H
Year: 2014
Journal: J Clin Invest
Title: Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis.
Volume: 124
Issue: 12
Pages: 5442-52
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Publication
29556001 | J:282434
First Author: Kuan EL
Year: 2018
Journal: Nat Immunol
Title: A tumor-myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer.
Volume: 19
Issue: 4
Pages: 366-374
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Publication
17974483 | J:130293
First Author: Lin Y
Year: 2008
Journal: Clin Immunol
Title: TSLP-induced placental DC activation and IL-10(+) NK cell expansion: comparative study based on BALB/c x C57BL/6 and NOD/SCID x C57BL/6 pregnant models.
Volume: 126
Issue: 1
Pages: 104-17
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Publication
23275605 | J:193032
First Author: Han H
Year: 2013
Journal: J Immunol
Title: Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages.
Volume: 190
Issue: 3
Pages: 904-12
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Publication
23079658 | J:192029
First Author: Di Piazza M
Year: 2012
Journal: Cancer Cell
Title: Loss of cutaneous TSLP-dependent immune responses skews the balance of inflammation from tumor protective to tumor promoting.
Volume: 22
Issue: 4
Pages: 479-93
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Publication
34326208 | J:324860
 
First Author: Choa R
Year: 2021
Journal: Science
Title: Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion.
Volume: 373
Issue: 6554
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Publication
38030609 | J:343267
First Author: Lee SH
Year: 2023
Journal: Nat Commun
Title: Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis.
Volume: 14
Issue: 1
Pages: 7852
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Publication
26927668 | J:234571
First Author: Demehri S
Year: 2016
Journal: J Clin Invest
Title: Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis.
Volume: 126
Issue: 4
Pages: 1458-70
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Publication
8566050 | J:33087
First Author: Ray RJ
Year: 1996
Journal: Eur J Immunol
Title: Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro.
Volume: 26
Issue: 1
Pages: 10-6
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Publication
26310839 | J:246803
First Author: Mizutani N
Year: 2015
Journal: Immunology
Title: Thymic stromal lymphopoietin-induced interleukin-17A is involved in the development of IgE-mediated atopic dermatitis-like skin lesions in mice.
Volume: 146
Issue: 4
Pages: 568-81
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Publication
11733384 | J:72982
First Author: Taneda S
Year: 2001
Journal: Am J Pathol
Title: Cryoglobulinemic glomerulonephritis in thymic stromal lymphopoietin transgenic mice.
Volume: 159
Issue: 6
Pages: 2355-69
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Publication
33514510 | J:303897
First Author: Malinczak CA
Year: 2021
Journal: J Immunol
Title: TSLP-Driven Chromatin Remodeling and Trained Systemic Immunity after Neonatal Respiratory Viral Infection.
Volume: 206
Issue: 6
Pages: 1315-1328
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Publication
23079659 | J:192028
First Author: Demehri S
Year: 2012
Journal: Cancer Cell
Title: Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin.
Volume: 22
Issue: 4
Pages: 494-505
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Publication
24632570 | J:245289
First Author: Verstraete K
Year: 2014
Journal: Nat Struct Mol Biol
Title: Structural basis of the proinflammatory signaling complex mediated by TSLP.
Volume: 21
Issue: 4
Pages: 375-82
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Publication
21690322 | J:179117
First Author: Kashyap M
Year: 2011
Journal: J Immunol
Title: Thymic stromal lymphopoietin is produced by dendritic cells.
Volume: 187
Issue: 3
Pages: 1207-11
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Publication
15263090 | J:91802
First Author: Vosshenrich CA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.
Volume: 101
Issue: 30
Pages: 11070-5
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Publication
18060034 | J:130832
First Author: Seshasayee D
Year: 2007
Journal: J Clin Invest
Title: In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Volume: 117
Issue: 12
Pages: 3868-78
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Publication
24157859 | J:319026
 
First Author: Kabata H
Year: 2013
Journal: Nat Commun
Title: Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.
Volume: 4
Pages: 2675
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Publication
18507503 | J:139386
First Author: Demehri S
Year: 2008
Journal: PLoS Biol
Title: Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.
Volume: 6
Issue: 5
Pages: e123
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Publication
10974033 | J:64348
First Author: Sims JE
Year: 2000
Journal: J Exp Med
Title: Molecular cloning and biological characterization of a novel murine lymphoid growth factor.
Volume: 192
Issue: 5
Pages: 671-80
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Publication
24284909 | J:261257
 
First Author: Leyva-Castillo JM
Year: 2013
Journal: Nat Commun
Title: Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade.
Volume: 4
Pages: 2847
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Publication
21242516 | J:169154
First Author: Lei L
Year: 2011
Journal: J Immunol
Title: Thymic stromal lymphopoietin interferes with airway tolerance by suppressing the generation of antigen-specific regulatory T cells.
Volume: 186
Issue: 4
Pages: 2254-61
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Publication
19188585 | J:144466
First Author: Zhang Z
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.
Volume: 106
Issue: 5
Pages: 1536-41
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Publication
17237387 | J:143658
First Author: Omori M
Year: 2007
Journal: J Immunol
Title: Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin.
Volume: 178
Issue: 3
Pages: 1396-404
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Publication
23872715 | J:200080
First Author: Noti M
Year: 2013
Journal: Nat Med
Title: Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.
Volume: 19
Issue: 8
Pages: 1005-13
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Publication
20173025 | J:160104
First Author: Larson RP
Year: 2010
Journal: J Immunol
Title: Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.
Volume: 184
Issue: 6
Pages: 2974-84
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Publication
29752758 | J:339021
First Author: Nam SY
Year: 2018
Journal: Clin Exp Allergy
Title: Src-type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin-induced allergic rhinitis.
Volume: 48
Issue: 7
Pages: 875-889
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Publication
24560412 | J:287018
First Author: Noti M
Year: 2014
Journal: J Allergy Clin Immunol
Title: Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.
Volume: 133
Issue: 5
Pages: 1390-9, 1399.e1-6
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Publication
24489089 | J:209796
First Author: Shane HL
Year: 2014
Journal: J Immunol
Title: A direct and nonredundant role for thymic stromal lymphopoietin on antiviral CD8 T cell responses in the respiratory mucosa.
Volume: 192
Issue: 5
Pages: 2261-70
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Publication
19427817 | J:151454
First Author: Knisz J
Year: 2009
Journal: Clin Immunol
Title: Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation.
Volume: 132
Issue: 2
Pages: 277-84
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Publication
28092372 | J:259948
First Author: Kashiwagi M
Year: 2017
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