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Search results 1 to 76 out of 76 for Tsx

0.035s
Type Details Score
Protein Domain
Type: Family
Description: The Tsx gene resides at the X-inactivation centre and once thought to encode a protein expressed in testis. However, this was disputed upon further analysis. ORF and immunostaining analysis concluded that Tsx may be non-coding. Tsx long transcript is abundantly expressed in meiotic germ cells, embryonic stem cells, and brain [].
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Anguera MC
Year: 2011
Journal: PLoS Genet
Title: Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain.
Volume: 7
Issue: 9
Pages: e1002248
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
Publication
First Author: Simmler MC
Year: 1996
Journal: Hum Mol Genet
Title: A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich region containing a new testis specific gene Tsx.
Volume: 5
Issue: 11
Pages: 1713-26
Publication
First Author: Cunningham DB
Year: 1998
Journal: Dev Biol
Title: The mouse Tsx gene is expressed in Sertoli cells of the adult testis and transiently in premeiotic germ cells during puberty.
Volume: 204
Issue: 2
Pages: 345-60
Publication
First Author: Chureau C
Year: 2002
Journal: Genome Res
Title: Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine.
Volume: 12
Issue: 6
Pages: 894-908
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Unhavaithaya Y
Year: 2009
Journal: J Biol Chem
Title: MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation.
Volume: 284
Issue: 10
Pages: 6507-19
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Deng W
Year: 2002
Journal: Dev Cell
Title: miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis.
Volume: 2
Issue: 6
Pages: 819-30
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Beyret E
Year: 2011
Journal: Dev Biol
Title: Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse.
Volume: 355
Issue: 2
Pages: 215-26
Publication
First Author: Costoya JA
Year: 2004
Journal: Nat Genet
Title: Essential role of Plzf in maintenance of spermatogonial stem cells.
Volume: 36
Issue: 6
Pages: 653-9
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Debrand E
Year: 1999
Journal: Mol Cell Biol
Title: Functional analysis of the DXPas34 locus, a 3' regulator of Xist expression.
Volume: 19
Issue: 12
Pages: 8513-25
Publication
First Author: Morey C
Year: 2004
Journal: EMBO J
Title: The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene.
Volume: 23
Issue: 3
Pages: 594-604
Publication
First Author: Rowntree RK
Year: 2006
Journal: Mol Cell Biol
Title: Mapping of DNA replication origins to noncoding genes of the X-inactivation center.
Volume: 26
Issue: 10
Pages: 3707-17
Publication
First Author: Bao J
Year: 2013
Journal: Biol Reprod
Title: Expression profiling reveals developmentally regulated lncRNA repertoire in the mouse male germline.
Volume: 89
Issue: 5
Pages: 107
GXD Expression  
Probe: MGI:5707836
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707858
Age: postnatal adult
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5707836
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707858
Age: postnatal adult
Image: S2C
Specimen Label: S2C
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5707836
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707858
Age: postnatal adult
Image: S2D
Specimen Label: S2D
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5816888
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-08
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5816886
Age: postnatal adult
Specimen Label: 3D
Detected: true
Specimen Num: 1
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Bremer E
Year: 1990
Journal: Gene
Title: Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli.
Volume: 96
Issue: 1
Pages: 59-65
Protein Domain
Type: Family
Description: The tsx gene of Escherichia coli encodes an outer membrane protein, Tsx,which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides []. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. The putative mature form of Tsx contains 272 residues with a calculated Mr of31418. The Tsx sequence shows an even distribution of charged residuesand lacks extensive hydrophobic stretches []. Tsx shows no significant similarities to the channel-forming proteins OmpC, OmpF, PhoE and LamB from the E. coli outer membrane.
UniProt Feature
Begin: 1
Description: Testis-specific protein TSX
Type: chain
End: 144
Protein Domain
Type: Homologous_superfamily
Description: The tsx gene of Escherichia coli encodes an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides []. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. The putative mature form of Tsx contains 272 residues with a calculated Mr of 31418. The Tsx sequence shows an even distribution of charged residues and lacks extensive hydrophobic stretches []. Tsx shows no significant similarities to the channel-forming proteins OmpC, OmpF, PhoE and LamB from the E. coli outer membrane.This entry also contains related proteins of unknown function.
Protein Domain
Type: Family
Description: The tsx gene of Escherichia coli encodes an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides []. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. The putative mature form of Tsx contains 272 residues with a calculated Mrof 31418. The Tsx sequence shows an even distribution of charged residues and lacks extensive hydrophobic stretches []. Tsx shows no significant similarities to the channel-forming proteins OmpC, OmpF, PhoE and LamB from the E. coli outer membrane.This entry also contains related proteins of unknown function.
Publication
First Author: Barnéoud-Arnoulet A
Year: 2010
Journal: J Bacteriol
Title: Interaction of the colicin K bactericidal toxin with components of its import machinery in the periplasm of Escherichia coli.
Volume: 192
Issue: 22
Pages: 5934-42
Publication
First Author: Pilsl H
Year: 1995
Journal: J Bacteriol
Title: Strong function-related homology between the pore-forming colicins K and 5.
Volume: 177
Issue: 23
Pages: 6973-7
Protein Domain
Type: Family
Description: Colicins are bacterial toxins produced by Escherichia coli strains and are active against E. coli or related strains. These bacterial antibiotic toxins play an important role in the E. coli colonization of environmental niches. Colicin K uses the Tsx nucleoside-specific receptor for binding at the cell surface, the OmpA protein for translocation through the outer membrane, and the TolABQR proteins for the transit through the periplasm. The N-terminal domain interacts with components of its import machinery, including the TolB and TolQ proteins []. Members of this family are colicin K immunity proteins. These proteins are able to protect a cell against colicin K [].
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89